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Trazodone hydrochloride

Catalog #: 6336 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6336/50
Trazodone hydrochloride | CAS No. 25332-39-2 | 5-HT2A Receptor Antagonists
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Description: 5-HT2A and α1 adrenoceptor antagonist; also enhances neural differentiation; antidepressant and neuroprotectant

Chemical Name: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride

Purity: ≥99%

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Biological Activity

Trazodone hydrochloride is a 5-HT2A and α1 adrenoceptor antagonist. Enhances neuronal differentiation of mouse and human neural progenitor cells. Also inhibits PERK/eIF2α-P-mediated reduction in protein synthesis and restores memory deficits in a mouse dementia model. Antidepressant and neuroprotectant.

Technical Data

M.Wt:
408.32
Formula:
C19H22ClN5O.HCl
Solubility:
Soluble to 20 mM in water and to 50 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
25332-39-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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