TumorTACS In Situ Apoptosis Detection Kit

Catalog # Availability Size / Price Qty
4815-30-K
TumorTACS In Situ Apoptosis Detection Kit_Mammary Tumor_4815-30-K
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Citations (21)
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TumorTACS In Situ Apoptosis Detection Kit Summary

TumorTACS® in situ

TumorTACS® in situ (Catalog # 4815-30-K)
Apoptotic Cells within a Mouse Mammary Tumor Identified using the Tumor TACS Kit
Mammary tumor was fixed in 4% paraformaldehyde overnight and paraffin-embedded. Five micron sections were prepared and placed onto glass microscope slides. The sample was processed following the TumorTACS Kit protocol (Catalog # 4815-30-K). Brown stained nuclei indicated apoptotic cells.

Complete kits contain Streptavidin-HRP, DAB, Methyl Green counterstain, and reagents necessary for generating positive controls. Kits are optimized for detection of apoptosis in tumor samples.

Label: Biotin/Streptavidin-HRP/DAB
Testing Format: Light Microscopy
Sample Type: Fixed cells, Embedded tissues, Frozen tissues
Size: 30 Tests


TumorTACS is a trademark of Trevigen, Inc.

Specifications

Shipping Conditions
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Storage
The product  requires storage at both -20 to -70 °C and 2 - 8 °C.  Consult the product insert for specific storage temperatures. Do not use past expiration date.

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Scientific Data

Apoptotic Cells within a Mouse Mammary Tumor Identified using the TumorTACS In Situ Apoptosis Detection Kit. Mammary tumor tissue was fixed in 4% paraformaldehyde overnight and paraffin-embedded. Five micron sections were prepared and placed onto glass microscope slides. The sample was processed following the TumorTACS Kit protocol (Catalog # 4815-30-K). Brown stained nuclei indicate apoptotic cells.

Citations for TumorTACS In Situ Apoptosis Detection Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

21 Citations: Showing 1 - 10
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  1. Renal and hepatic artery embolization with Pickering gel emulsion of lipiodol in rabbit
    Authors: H Zhang, Y Ren, H Li, C Zheng, K Qian
    BMC Cancer, 2022-12-12;22(1):1300.  2022-12-12
  2. Multi-Lens Arrays (MLA)-Assisted Photothermal Effects for Enhanced Fractional Cancer Treatment: Computational and Experimental Validations
    Authors: H Kim, H Pyo, H Kim, HW Kang
    Cancers, 2021-03-08;13(5):.  2021-03-08
  3. Co-administration of H-ferritin-doxorubicin and Trastuzumab in neoadjuvant setting improves efficacy and prevents cardiotoxicity in HER2?+?murine breast cancer model
    Authors: F Andreata, A Bonizzi, M Sevieri, M Truffi, M Monieri, L Sitia, F Silva, L Sorrentino, R Allevi, P Zerbi, B Marchini, E Longhi, R Ottria, S Casati, R Vanna, C Morasso, M Bellini, D Prosperi, F Corsi, S Mazzucchel
    Sci Rep, 2020-07-10;10(1):11425.  2020-07-10
  4. Inhibition of Heparanase Expression Results in Suppression of Invasion, Migration and Adhesion Abilities of Bladder Cancer Cells
    Authors: Y Tatsumi, M Miyake, K Shimada, T Fujii, S Hori, Y Morizawa, Y Nakai, S Anai, N Tanaka, N Konishi, K Fujimoto
    Int J Mol Sci, 2020-05-27;21(11):.  2020-05-27
  5. Tussilagone Reduces Tumorigenesis by Diminishing Inflammation in Experimental Colitis-Associated Colon Cancer
    Authors: SH Nam, JK Kim
    Biomedicines, 2020-04-11;8(4):.  2020-04-11
  6. Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma
    Authors: X Liu, J Hu, X Song, K Utpatel, Y Zhang, P Wang, X Lu, J Zhang, M Xu, T Su, L Che, J Wang, M Evert, DF Calvisi, X Chen
    Cancers (Basel), 2019-07-03;11(7):.  2019-07-03
  7. SPARC correlates with unfavorable outcome and promotes tumor growth in lung squamous cell carcinoma
    Authors: J Xu, S Yang, X Gu, H Shen, L Wang, W Xu, L Fang, Y Mao, L Xu, Y Chen, W Fan, J Wang
    Exp. Mol. Pathol., 2019-06-21;0(0):104276.  2019-06-21
  8. IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration
    Authors: P Guha, R Tyagi, S Chowdhury, L Reilly, C Fu, R Xu, AC Resnick, SH Snyder
    Cell Rep, 2019-03-05;26(10):2692-2703.e7.  2019-03-05
  9. Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression
    Authors: SP Kalainayak, P Ghosh, S Dey, KE Fitzgerald, S Sohoni, PC Konduri, M Garrossian, L Liu, L Zhang
    Sci Rep, 2019-02-05;9(1):1405.  2019-02-05
  10. Non-obstructive vas deferens and epididymis loss in cystic fibrosis rats
    Authors: ZE Plyler, SE Birket, BD Schultz, JS Hong, SM Rowe, CF Petty, MR Crowley, DK Crossman, TR Schoeb, EJ Sorscher
    Mech. Dev., 2018-11-02;155(0):15-26.  2018-11-02
  11. Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma.
    Authors: Barone T, Burkhart C, Safina A, Haderski G, Gurova K, Purmal A, Gudkov A, Plunkett R
    Neuro Oncol, 2017-02-01;19(2):186-196.  2017-02-01
  12. Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma.
    Authors: Jain S, Stroopinsky D, Yin L, Rosenblatt J, Alam M, Bhargava P, Clark R, Kupper T, Palmer K, Coll M, Rajabi H, Pyzer A, Bar-Natan M, Luptakova K, Arnason J, Joyce R, Kufe D, Avigan D
    Blood, 2015-06-05;126(3):354-62.  2015-06-05
  13. Preclinical pharmacologic evaluation of pralatrexate and romidepsin confirms potent synergy of the combination in a murine model of human T-cell lymphoma.
    Authors: Jain S, Jirau-Serrano X, Zullo K, Scotto L, Palermo C, Sastra S, Olive K, Cremers S, Thomas T, Wei Y, Zhang Y, Bhagat G, Amengual J, Deng C, Karan C, Realubit R, Bates S, O'Connor O
    Clin Cancer Res, 2015-02-12;21(9):2096-106.  2015-02-12
  14. Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways.
    Authors: Lin, Jiumao, Shen, Aling, Chen, Hongwei, Liao, Jun, Xu, Teng, Liu, Liya, Lin, Jing, Peng, Jun
    BMC Cancer, 2014-09-30;14(0):729.  2014-09-30
  15. TNF-related apoptosis-inducing ligand enhances vinorelbine-induced apoptosis and antitumor activity in a preclinical model of non-small cell lung cancer.
    Authors: Zhu K, Fang W, Chen Y, Lin S, Chen X
    Oncol Rep, 2014-07-11;32(3):1234-42.  2014-07-11
  16. Bifurcation of axons from cranial sensory neurons is disabled in the absence of Npr2-induced cGMP signaling.
    Authors: Ter-Avetisyan G, Rathjen F, Schmidt H
    J Neurosci, 2014-01-15;34(3):737-47.  2014-01-15
  17. Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma.
    Authors: Hua Y, White-Gilbertson S, Kellner J, Rachidi S, Usmani S, Chiosis G, Depinho R, Li Z, Liu B
    Clin Cancer Res, 2013-09-27;19(22):6242-51.  2013-09-27
  18. Distinct phospholipase C-beta isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure.
    Authors: Lee S, Leoni G, Neumann P, Chun J, Nusrat A, Yun C
    Mol Cell Biol, 2013-03-11;33(10):2016-28.  2013-03-11
  19. Experimental mild renal insufficiency mediates early cardiac apoptosis, fibrosis, and diastolic dysfunction: a kidney-heart connection.
    Authors: Martin F, McKie P, Cataliotti A, Sangaralingham S, Korinek J, Huntley B, Oehler E, Harders G, Ichiki T, Mangiafico S, Nath K, Redfield M, Chen H, Burnett J
    Am J Physiol Regul Integr Comp Physiol, 2011-11-09;302(2):R292-9.  2011-11-09
  20. Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells.
    Authors: Liu Y, Sun S, Owonikoko T, Sica G, Curran W, Khuri F, Deng X
    Mol Cancer Ther, 2011-11-04;11(1):45-56.  2011-11-04
  21. Recombinant VP1, an Akt inhibitor, suppresses progression of hepatocellular carcinoma by inducing apoptosis and modulation of CCL2 production.
    Authors: Chen TA, Wang JL, Hung SW, Chu CL, Cheng YC, Liang SM
    PLoS ONE, 2011-08-03;6(8):e23317.  2011-08-03

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