Nuclear Hormone Receptors
Nuclear hormone receptors are key targets for drug development as many are implicated in diabetes and other endocrine disorders as well as cancer. These molecules are ligand-dependent transcription factors that regulate gene expression in response to a wide range of developmental, physiological, and environmental cues. R&D Systems offers the most complete selection of highly specific monoclonal antibodies to the nuclear hormone receptor protein family available.
- Androgen R/NR3C4
- CAR/NR1I3
- COUP-TF I/NR2F1
- COUP-TF II/NR2F2
- DAX1/NR0B1
- EAR2/NR2F6
- ER alpha/NR3A1
- ER beta/NR3A2
- ERR alpha/NR3B1
- ERR beta/NR3B2
- ERR gamma/NR3B3
- FXR/NR1H4
- GCNF/NR6A1
- GR/NR3C1
- HNF-4 alpha/NR2A1
- HNF-4 gamma/NR2A2
- LRH-1/NR5A2
- LXR alpha/NR1H3
- LXR beta/NR1H2
- Mineralocorticoid R/NR3C2
- NGFI-B alpha/Nur77/NR4A1
- NGFI-B gamma/NOR-1/NR4A3
- Nurr1/NGFI-B beta/NR4A2
- PNR/NR2E3
- PPAR alpha/NR1C1
- PPAR gamma/NR1C3
- PPAR delta/NR1C2
- Progesterone R/NR3C3
- Progesterone R B/NR3C3
- PXR/NR1I2
- RAR alpha/NR1B1
- RAR beta/NR1B2
- RAR gamma/NR1B3
- Rev-erb A alpha/NR1D1
- Rev-erb beta/NR1D2
- ROR/NR1F1-3 (pan)
- ROR alpha/NR1F1
- ROR beta/NR1F2
- ROR gamma/RORC/NR1F3
- ROR gamma t/RORC2/NR1F3
- ROR/NR1F Agonists
- ROR/NR1F Antagonists
- Additional ROR/NR1F Compounds
- RXR alpha/NR2B1
- RXR beta/NR2B2
- RXR gamma/NR2B3
- SF-1/NR5A1
- SHP/NR0B2
- TLX/NR2E1
- TR alpha/NR1A1
- TR beta 1/NR1A2
- TR2/NR2C1
- TR4/NR2C2
- VDR/NR1I1