This eBook provides a primer on the history, current state, and future use of cell based 2 D and 3 D model systems for toxicology, drug screening, and disease modeling. Included are chapters on primary cells, cell lines, stem cells, 3 D cell culture models, and more complex tissue and organ modeling systems.
Key Topics
- Primary and cell lines for toxicology
- Pluripotent stem cell models
- 2 D vs. 3 D cell culture
- Organoid benefits and challenges
- Future models and challenges
- Toxicology assays
Infographics and Interactive Features for Cell Culture Models
- ADME/Tox specifications
- Commonly-used cell lines, categorized by organ
- 2 D vs. 3 D model systems
- Organoid reagent guide
Related Information
Organoid and 3-D Cell Culture Resources and Reagents
Induced Pluripotent Stem Cell (iPSC) Reagents
Cultrex Basement Membrane Extracts and Extracellular Matrices