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CoraFluor™ 1, thiol reactive

Catalog #: 8117 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8117/20U
CoraFluor™ 1, thiol reactive | Fluorescent Probes
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Description: Terbium cryptate FRET donor for TR-FRET assay development, cysteine reactive for conjugation
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Biological Activity

CoraFluor™ 1, thiol reactive is a terbium-based time-resolved Förster resonance energy transfer (TR-FRET) donor for TR-FRET assay development, such as target engagement and ternary complex assays. This product is designed with maleimide functionality to conjugate to cysteines, making it suitable for labeling biomolecules, including antibodies, nanobodies, proteins and peptides. It is exceptionally bright, providing unmatched assay sensitivity and stability in biological media over other commercially available TR-FRET donors. CoraFluor™ 1, thiol reactive is compatible with common acceptor dyes such as FAM, TMR and Cyanine 5, SE (Cat. No. 5436), enabling seamless assay integration in high throughput screening applications.

CoraFluor™ 1, amine reactive and CoraFluor™ 2, amine reactive also available.

Please refer to the protocol for further information on conjugation.

CoraFluor™ is a trademark of Bio-Techne Corp.

Optical Data for CoraFluor™ 1, thiol reactive

CoraFluor™ 1, thiol reactive Dye Spectra
λabs 338 nm
Closest Laser line 337 nm
Reactive Group Maleimide
Reactivity Thiols
Cell Permeable No
Correction Factor 280 0.157
Application Time-resolved fluorescence energy transfer (TR-FRET)

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Spectral Viewer

Technical Data

M.Wt:
1441.33
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Product Datasheets

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.