Cyno Monkey IL-7RA/CD127 (ABB13531.1) VersaClone cDNA

Cyno Monkey IL-7RA/CD127 (ABB13531.1) VersaClone cDNA Summary

Specifications

Product Datasheets

Background: IL-7R alpha/CD127

The biological effects of IL-7 are mediated by the binding of IL-7 to the specific cell surface receptor complex. The functional high-affinity IL-7 receptor (IL-7 R) comprises the IL-7 R alpha chain in association with the common gamma chain (gamma c). Both IL-7 R alpha and gamma c are members of the hematopoietin receptor superfamily. Human and mouse IL-7 R alpha show 64% amino acid sequence identity. IL-7 R alpha transcripts were observed in murine spleen, thymus, fetal liver, developing T cells, B cells, mature T cells and bone marrow-derived macrophages.

Related Research Areas

• B Cell Development and Differentiation
• B Cell Markers
• Common gamma Chain Receptor Family
• Group 1 ILCs
• Group 2 ILCs
• Hematopoietic Progenitor Cell Markers
• Isolation, Culture, and Identification of Natural Killer Cells
• LTi Cells
• Lymphoid Lineage Markers
• Natural Killer T (NKT) Cells
• NCR+ILC3
• NCR-ILC3
• Receptors in the Jak/STAT Pathway
• Regulatory T Cells (Tregs)
• T Cell Cytokine Signaling