Human IL-12 p70 Quantikine ELISA Kit Summary
Product Summary
Precision
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 20 | 20 | 20 |
Mean (pg/mL) | 21.2 | 228 | 447 | 21 | 126 | 246 |
Standard Deviation | 0.3 | 3.5 | 4.9 | 1.5 | 5.6 | 8.1 |
CV% | 1.4 | 1.5 | 1.1 | 7.1 | 4.4 | 3.3 |
Urine
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 20 | 20 | 20 |
Mean (pg/mL) | 25.7 | 202 | 436 | 19.9 | 115 | 223 |
Standard Deviation | 1.6 | 4.8 | 10.1 | 1.9 | 8.3 | 13.2 |
CV% | 6.2 | 2.4 | 2.3 | 9.5 | 7.2 | 5.9 |
Recovery
The recovery of human IL-12 spiked to three different levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Media (n=5) | 90 | 81-96 |
Citrate Plasma (n=5) | 90 | 82-94 |
EDTA Plasma (n=5) | 101 | 96-109 |
Heparin Plasma (n=5) | 99 | 89-109 |
Serum (n=5) | 100 | 89-106 |
Urine (n=5) | 89 | 85-92 |
Linearity
Scientific Data
Preparation and Storage
Background: IL-12 p70
Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.
Assay Procedure
Refer to the product- Prepare all reagents, working standards, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 50 µL of the appropriate Assay Diluent to each well.
- Add 200 µL of Standard, control, or sample to each well. Cover with a plate sealer.
- For Cell Culture Supernate, Serum & Plasma Samples: Incubate at room temperature for 2 hours.
For Urine Samples: Incubate at room temperature for 1.5 hours. - Aspirate each well and wash, repeating the process twice for a total of 3 washes.
- Add 200 µL of Conjugate to each well, and cover with a new plate sealer.
- For Cell Culture Supernate, Serum & Plasma Samples: Incubate at room temperature for 2 hours.
For Urine Samples: Incubate at room temperature for 1.5 hours. - Aspirate and wash 3 times.
- Add 200 µL Substrate Solution to each well. Incubate at room temperature for 20 minutes. PROTECT FROM LIGHT.
- Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Human IL-12 p70 Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Safety and Efficacy of IL-12 Plasmid DNA Transfection into Pig Skin: Supportive Data for Human Clinical Trials on Gene Therapy and Vaccination
Authors: Lampreht Tratar, U;Jesenko, T;Omerzel, M;Seliskar, A;Stupan, U;Djokic, M;Sredensek, J;Trotovsek, B;Sersa, G;Cemazar, M;
International journal of molecular sciences
Species: Xenograft
Sample Types: Tissue Homogenates
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Combination IFNbeta and membrane-stable CD40L maximize tumor dendritic cell activation and lymph node trafficking to elicit systemic T-cell immunity
Authors: H Zheng, X Yu, ML Ibrahim, D Foresman, M Xie, JO Johnson, TA Boyle, B Ruffell, BA Perez, SJ Antonia, N Ready, AN Saltos, MJ Cantwell, AA Beg
Cancer Immunology Research, 2023-04-03;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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WT1 Pulsed Human CD141+ Dendritic Cell Vaccine Has High Potential in Solid Tumor-Targeted Immunotherapy
Authors: SY Cho, SM Jeong, YJ Jeon, SJ Yang, JE Hwang, BM Yoo, HS Kim
International Journal of Molecular Sciences, 2023-01-12;24(2):.
Species: Human
Sample Types: Cell Culture Supernates
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Potential Protective Role of Galectin-3 in Patients with Gonarthrosis and Diabetes Mellitus: A Cross-Sectional Study
Authors: J Milosevic, M Jurisevic, V Grbovic, I Jovanovic, N Gajovic, A Jurisic-Sk
International Journal of Environmental Research and Public Health, 2022-09-13;19(18):.
Species: Human
Sample Types: Serum
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Mesothelin?specific T cell cytotoxicity against triple negative breast cancer is enhanced by 40s ribosomal protein subunit 3?treated self?differentiated dendritic cells
Authors: N Jirapongwa, S Thongchot, W Chiraphapp, T Chieochans, D Sa-Nguanra, M Warnnissor, P Thuwajit, PT Yenchitsom, C Thuwajit
Oncology reports, 2022-05-26;48(1):.
Species: Human
Sample Types: Cell Culture Supernates
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Nanoplastics affect the inflammatory cytokine release by primary human monocytes and dendritic cells
Authors: A Weber, A Schwiebs, H Solhaug, J Stenvik, AM Nilsen, M Wagner, B Relja, HH Radeke
Environment international, 2022-03-15;163(0):107173.
Species: Human
Sample Types: Cell Culture Supernates
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Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma
Authors: DH Lee, HK Park, HR Lee, H Sohn, S Sim, HJ Park, YS Shin, YK Kim, Y Choi, HS Park
Clinical and translational allergy, 2022-03-01;12(3):e12138.
Species: Human
Sample Types: Cell Culture Supernates
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Glioma Stem Cells Upregulate CD39 Expression to Escape Immune Response through SOX2 Modulation
Authors: B Liu, Y Cao, Y Li, H Ma, M Yang, Q Zhang, G Li, K Zhang, Y Wu, Y Zhou, W Yang, T Sun
Cancers, 2022-02-03;14(3):.
Species: Human
Sample Types: Cell Culture Supernates
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Non-Clinical In Vitro Evaluation of Antibiotic Resistance Gene-Free Plasmids Encoding Human or Murine IL-12 Intended for First-in-Human Clinical Study
Authors: S Kos, M Bosnjak, T Jesenko, B Markelc, U Kamensek, K Znidar, U Matkovic, A Rencelj, G Sersa, R Hudej, A Tuljak, M Peterka, M Cemazar
Pharmaceutics, 2021-10-19;13(10):.
Species: Human
Sample Types: Cell Culture Supernates
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Macrophages exert homeostatic actions in pregnancy to protect against preterm birth and fetal inflammatory injury
Authors: N Gomez-Lope, V Garcia-Flo, PY Chin, HM Groome, MT Bijland, KR Diener, R Romero, SA Robertson
JCI Insight, 2021-10-08;6(19):.
Species: Human
Sample Types: Cell Culture Supernates
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Association of Sarcopenia and Gut Microbiota Composition in Older Patients with Advanced Chronic Kidney Disease, Investigation of the Interactions with Uremic Toxins, Inflammation and Oxidative Stress
Authors: E Margiotta, L Caldiroli, ML Callegari, F Miragoli, F Zanoni, S Armelloni, V Rizzo, P Messa, S Vettoretti
Toxins, 2021-07-08;13(7):.
Species: Human
Sample Types: Serum
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Association between the uremic toxins indoxyl-sulfate and p-cresyl-sulfate with sarcopenia and malnutrition in elderly patients with advanced chronic kidney disease
Authors: L Caldiroli, S Armelloni, A Eskander, P Messa, V Rizzo, E Margiotta, M Cesari, S Vettoretti
Experimental gerontology, 2021-01-30;147(0):111266.
Species: Human
Sample Types: Serum
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Oxidized LDL Disrupts Metabolism and Inhibits Macrophage Survival by Activating a miR-9/Drp1/Mitochondrial Fission Signaling Pathway
Authors: T Xin, C Lu, J Zhang, J Wen, S Yan, C Li, F Zhang, J Zhang
Oxid Med Cell Longev, 2020-11-01;2020(0):8848930.
Species: Human
Sample Types: Cell Culture Supernates
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Comparative analysis of the tear protein profile in herpes simplex virus type 1 epithelial keratitis
Authors: H Yang, X Yang, Y Wang, X Zheng, Y Zhang, Y Shao
BMC Ophthalmol, 2020-08-31;20(1):355.
Species: Human
Sample Types: Tears
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Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations
Authors: P Ruscitti, P Di Benedet, O Berardicur, N Panzera, N Grazia, AR Lizzi, P Cipriani, Y Shoenfeld, R Giacomelli
Sci Rep, 2020-07-22;10(1):12232.
Species: Human
Sample Types: Cell Culture Supernates
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Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review
Authors: M Herrera, C Vera, Y Keynan, ZV Rueda
J Immunol Res, 2020-04-21;2020(0):8074183.
Species: Human
Sample Types: Plasma
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Dioscin attenuates oxLDL uptake and the inflammatory reaction of dendritic cells under high glucose conditions by blocking p38 MAPK
Authors: Y Li, Y Li, T Yang, M Wang
Mol Med Rep, 2019-11-06;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer
Authors: MJ Kim, BH Chi, JJ Yoo, YM Ju, YM Whang, IH Chang
PLoS ONE, 2019-10-22;14(10):e0223689.
Species: Human
Sample Types: Cell Culture Supernates
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Sarcopenia is Associated with Malnutrition but Not with Systemic Inflammation in Older Persons with Advanced CKD
Authors: S Vettoretti, L Caldiroli, S Armelloni, C Ferrari, M Cesari, P Messa
Nutrients, 2019-06-19;11(6):.
Species: Human
Sample Types: Serum
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Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging
Authors: DP Muñoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lope, M Kawahara, AM Freund, F Rodier, JD Wu, PY Desprez, DH Raulet, PS Nelson, LJ van 't Vee, J Campisi, JP Coppé
JCI Insight, 2019-06-11;5(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Circulating growth/differentiation factor 15 is associated with human CD56bright natural killer cell dysfunction and nosocomial infection in severe systemic inflammation
Authors: H Kleinertz, M Hepner-Sch, S Ehnert, M Claus, R Halbgebaue, L Boller, M Huber-Lang, P Cinelli, C Kirschning, S Flohé, A Sander, C Waydhas, S Vonderhage, M Jäger, M Dudda, C Watzl, SB Flohé
EBioMedicine, 2019-04-13;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Plasma levels of TNF-?, IL-6, IFN-?, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD)
Authors: S Clayton, E Cauble, A Kumar, N Patil, D Ledford, N Kolliputi, MF Lopes-Vire, D Castell, J Richter
BMC Gastroenterol, 2019-02-11;19(1):28.
Species: Human
Sample Types: Plasma
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Mesenchymal stem cell transplantation ameliorates Sj�gren's syndrome via suppressing IL-12 production by dendritic cells
Authors: B Shi, J Qi, G Yao, R Feng, Z Zhang, D Wang, C Chen, X Tang, L Lu, W Chen, L Sun
Stem Cell Res Ther, 2018-11-08;9(1):308.
Species: Human
Sample Types: Serum
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Snail-overexpressing Cancer Cells Promote M2-Like Polarization of Tumor-Associated Macrophages by Delivering MiR-21-Abundant Exosomes
Authors: CH Hsieh, SK Tai, MH Yang
Neoplasia, 2018-07-02;20(8):775-788.
Species: Human
Sample Types: Exosomes
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Factors Influencing the Differentiation of Human Monocytic Myeloid-Derived Suppressor Cells Into Inflammatory Macrophages
Authors: D Bayik, D Tross, DM Klinman
Front Immunol, 2018-03-26;9(0):608.
Species: Human
Sample Types: Cell Culture Supernates
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Clinically Usable Interleukin 12 Plasmid without an Antibiotic Resistance Gene: Functionality and Toxicity Study in Murine Melanoma Model
Authors: U Kamensek, N Tesic, G Sersa, M Cemazar
Cancers (Basel), 2018-02-27;10(3):.
Species: Mouse
Sample Types: Cell Culture Supernates
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HCMV requires EGFR signaling to enter and initiate the early steps in the establishment of latency in CD34+ human progenitor cells
Authors: Jung Heon Kim
J. Virol, 2017-02-14;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations
Authors: Y Wang, CS Ma, Y Ling, A Bousfiha, Y Camcioglu, S Jacquot, K Payne, E Crestani, R Roncagalli, A Belkadi, G Kerner, L Lorenzo, C Deswarte, M Chrabieh, E Patin, QB Vincent, I Müller-Fle, B Fleckenste, F Ailal, L Quintana-M, S Fraitag, MA Alyanakian, M Leruez-Vil, C Picard, A Puel, J Bustamante, S Boisson-Du, M Malissen, B Malissen, L Abel, A Hovnanian, LD Notarangel, E Jouanguy, SG Tangye, V Béziat, JL Casanova
J. Exp. Med., 2016-09-19;213(11):2413-2435.
Species: Human
Sample Types: Whole Blood
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Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.
Authors: Paoloni M, Mazcko C, Selting K, Lana S, Barber L, Phillips J, Skorupski K, Vail D, Wilson H, Biller B, Avery A, Kiupel M, LeBlanc A, Bernhardt A, Brunkhorst B, Tighe R, Khanna C
PLoS ONE, 2015-06-19;10(6):e0129954.
Species: Human
Sample Types: Serum
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Live attenuated B. pertussis BPZE1 rescues the immune functions of Respiratory Syncytial virus infected human dendritic cells by promoting Th1/Th17 responses.
Authors: Schiavoni I, Fedele G, Quattrini A, Bianco M, Schnoeller C, Openshaw P, Locht C, Ausiello C
PLoS ONE, 2014-06-26;9(6):e100166.
Species: Human
Sample Types: Cell Culture Supernates
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Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity.
Authors: Krishnan G, Chatterjee N
Mol Cell Neurosci, 2014-01-11;59(0):10-23.
Species: Human
Sample Types: Cell Culture Supernates
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Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy.
Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
Br J Cancer, 2013-11-14;110(1):26-33.
Species: Human
Sample Types: Plasma
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Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages.
Authors: Haselow K, Bode J, Wammers M, Ehlting C, Keitel V, Kleinebrecht L, Schupp A, Haussinger D, Graf D
J Leukoc Biol, 2013-08-29;94(6):1253-64.
Species: Human
Sample Types: Cell Culture Supernates
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Efficacy of oncolytic adenovirus expressing suicide genes and interleukin-12 in preclinical model of prostate cancer.
Authors: Freytag, S O, Barton, K N, Zhang, Y
Gene Ther, 2013-07-11;20(12):1131-9.
Species: Human
Sample Types: Cell Culture Supernates
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Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission.
Authors: Beck B, Dorfel D, Lichtenegger FS, Geiger C, Lindner L, Merk M, Schendel DJ, Subklewe M
J Transl Med, 2011-09-13;9(0):151.
Species: Human
Sample Types: Cell Culture Supernates
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HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.
Authors: Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC
Leukemia, 2010-11-19;25(1):161-8.
Species: Human
Sample Types: Cell Culture Supernates
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Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma.
Authors: Vyth-Dreese FA, Sein J, van de Kasteele W, Dellemijn TA, van den Bogaard C, Nooijen WJ, de Gast GC, Haanen JB, Bex A
Clin. Exp. Immunol., 2010-10-05;162(3):447-59.
Species: Human
Sample Types: Plasma
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CD14-independent responses induced by a synthetic lipid A mimetic.
Authors: Legat A, Thomas S, Hermand P, Van Mechelen M, Goldman M, De Wit D
Eur J Immunol, 2010-03-01;40(3):797-802.
Species: Human
Sample Types: Cell Culture Supernates
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Immunologic markers as predictors of tuberculosis-associated immune reconstitution inflammatory syndrome in HIV and tuberculosis coinfected persons in Thailand.
Authors: Tieu HV, Ananworanich J, Avihingsanon A, Apateerapong W, Sirivichayakul S, Siangphoe U, Klongugkara S, Boonchokchai B, Hammer SM, Manosuthi W
AIDS Res. Hum. Retroviruses, 2009-11-01;25(11):1083-9.
Species: Human
Sample Types: Serum
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Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
Authors: Chase JC, Celli J, Bosio CM
Infect. Immun., 2008-11-03;77(1):180-95.
Species: Human
Sample Types: Cell Culture Supernates
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Cerebrospinal fluid levels of interleukin-6 and interleukin-12 in children with meningitis.
Authors: Hsieh CC, Lu JH, Chen SJ, Lan CC, Chow WC, Tang RB
Cytotechnology, 2008-09-25;25(4):461-5.
Species: Human
Sample Types: CSF
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In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22.
Authors: Olsnes AM, Ryningen A, Ersvaer E, Bruserud Ø
J. Interferon Cytokine Res., 2008-05-01;28(5):297-310.
Species: Human
Sample Types: Cell Culture Supernates
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Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.
Authors: Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S
Eur. J. Immunol., 2008-04-01;38(4):1012-23.
Species: Human
Sample Types: Cell Culture Supernates
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Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma.
Authors: Little RF, Aleman K, Kumar P, Wyvill KM, Pluda JM, Read-Connole E, Wang V, Pittaluga S, Catanzaro AT, Steinberg SM, Yarchoan R
Blood, 2007-09-10;110(13):4165-71.
Species: Human
Sample Types: Serum
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Translocation of bacterial DNA from Gram-positive microorganisms is associated with a species-specific inflammatory response in serum and ascitic fluid of patients with cirrhosis.
Authors: Frances R, Gonzalez-Navajas JM, Zapater P, Munoz C, Cano R, Pascual S, Santana F, Marquez D, Perez-Mateo M, Such J
Clin. Exp. Immunol., 2007-09-05;150(2):230-7.
Species: Human
Sample Types: Serum
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Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells.
Authors: Irhimeh MR, Fitton JH, Lowenthal RM
Exp. Hematol., 2007-06-01;35(6):989-94.
Species: Human
Sample Types: Plasma
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Chemokines CXCL10 and CXCL11 in the cerebrospinal fluid of patients with tick-borne encephalitis.
Authors: Lepej SZ, Misic-Majerus L, Jeren T, Rode OD, Remenar A, Sporec V, Vince A
Acta Neurol. Scand., 2007-02-01;115(2):109-14.
Species: Human
Sample Types: CSF
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IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production.
Authors: Vaknin-Dembinsky A, Balashov K, Weiner HL
J. Immunol., 2006-06-15;176(12):7768-74.
Species: Human
Sample Types: Cell Culture Supernates
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Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction.
Authors: Spensieri F, Fedele G, Fazio C, Nasso M, Stefanelli P, Mastrantonio P, Ausiello CM
Infect. Immun., 2006-05-01;74(5):2831-8.
Species: Human
Sample Types: Cell Culture Supernates
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Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer.
Authors: Ferrandina G, Ranelletti FO, Legge F, Salutari V, Martinelli E, Fattorossi A, Lorusso D, Zannoni G, Vellone V, Paglia A, Scambia G
Clin. Cancer Res., 2006-04-01;12(7):2055-60.
Species: Human
Sample Types: Plasma
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Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma.
Authors: Yoshikawa H, Sato K, Edahiro S, Furukawa Y, Maruta T, Iwasa K, Watanabe H, Takaoka S, Suzuki Y, Takamori M, Yamada M
J. Neuroimmunol., 2006-03-29;175(1):169-75.
Species: Human
Sample Types: Serum
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Chemokines indicate allergic bronchopulmonary aspergillosis in patients with cystic fibrosis.
Authors: Hartl D, Latzin P, Zissel G, Krane M, Krauss-Etschmann S, Griese M
Am. J. Respir. Crit. Care Med., 2006-03-16;173(12):1370-6.
Species: Human
Sample Types: Serum
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C-reactive protein and vascular cell adhesion molecule-1 as markers of severity in sickle cell disease.
Authors: Makis AC, Hatzimichael EC, Stebbing J, Bourantas KL
Arch. Intern. Med., 2006-02-13;166(3):366-8.
Species: Human
Sample Types: Plasma
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Interleukin-12 and interleukin-16 in periodontal disease.
Authors: Tsai IS, Tsai CC, Ho YP, Ho KY, Wu YM, Hung CC
Cytokine, 2005-07-07;31(1):34-40.
Species: Human
Sample Types:
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Effect of piceatannol in human monocyte-derived dendritic cells in vitro.
Authors: Takei M, Umeyama A, Arihara S, Matsumoto H
J Pharm Sci, 2005-05-01;94(5):974-82.
Species: Human
Sample Types: Cell Culture Supernates
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Manipulation of host cytokine network by ticks: a potential gateway for pathogen transmission.
Authors: Hajnicka V, Vancova I, Kocakova P, Slovak M, Gasperik J, Slavikova M, Hails RS, Labuda M, Nuttall PA
Parasitology, 2005-03-01;130(0):333-42.
Species: Human
Sample Types: Saliva
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Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b.
Authors: Jensen J, Krakauer M, Sellebjerg F
Cytokine, 2005-01-07;29(1):24-30.
Species: Human
Sample Types: Plasma
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Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
Authors: Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W
J. Immunol., 2004-10-01;173(7):4433-42.
Species: Human
Sample Types: Cell Culture Supernates
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Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients.
Authors: Saeki S, Matsuse H, Kondo Y, Machida I, Kawano T, Tomari S, Obase Y, Fukushima C, Kohno S
J. Allergy Clin. Immunol., 2004-09-01;114(3):538-44.
Species: Human
Sample Types: Cell Culture Supernates
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Production of interferon gamma in respiratory syncytial virus infection of humans is not associated with interleukins 12 and 18.
Authors: Garofalo RP, Hintz KH, Hill V, Ogra PL, Welliver RC
J. Med. Virol., 2004-06-01;73(2):289-94.
Species: Human
Sample Types: Tissue Secretion
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Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.
Authors: Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N
J. Virol., 2004-06-01;78(12):6151-61.
Species: Primate - Pan troglodytes (Chimpanzee)
Sample Types: Cell Culture Supernates
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Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: a pilot study.
Authors: Ciprandi G, Tosca MA, Milanese M, Caligo G, Ricca V
Pediatr Allergy Immunol, 2004-04-01;15(2):148-51.
Species: Human
Sample Types: Nasal Lavage Fluid
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Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries.
Authors: Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL
J. Androl., 2004-03-01;25(2):250-4.
Species: Human
Sample Types: Seminal Plasma
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Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria.
Authors: Chaiyaroj SC, Rutta AS, Muenthaisong K, Watkins P, Na Ubol M, Looareesuwan S
Acta Trop., 2004-02-01;89(3):319-27.
Species: Human
Sample Types: Plasma
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NK cells regulate CD8+ T cell effector function in response to an intracellular pathogen.
Authors: Vankayalapati R, Klucar P, Wizel B, Weis SE, Samten B, Safi H, Shams H, Barnes PF
J. Immunol., 2004-01-01;172(1):130-7.
Species: Human
Sample Types: Cell Culture Supernates
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HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection.
Authors: Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T
J. Immunol., 2002-12-01;169(11):6361-8.
Species: Human
Sample Types: Cell Culture Supernates
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Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma.
Authors: Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G
Int. J. Cancer, 2002-09-10;101(2):183-9.
Species: Human
Sample Types: Ascites Fluid
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Local immunostimulation induced by intravesical administration of autologous interferon-gamma-activated macrophages in patients with superficial bladder cancer.
Authors: Pages F, Lebel-Binay S, Vieillefond A, Deneux L, Cambillau M, Soubrane O, Debre B, Tardy D, Lemonne JL, Abastado JP, Fridman WH, Thiounn N
Clin. Exp. Immunol., 2002-02-01;127(2):303-9.
Species: Human
Sample Types: Urine
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Cytokine profile in Behcet's disease patients. Relationship with disease activity.
Authors: Hamzaoui K, Hamzaoui A, Guemira F, Bessioud M, Hamza M, Ayed K
Scand. J. Rheumatol., 2002-01-01;31(4):205-10.
Species: Human
Sample Types: Serum
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Mature dendritic cells infiltrate the T cell-rich region of oral mucosa in chronic periodontitis: in situ, in vivo, and in vitro studies.
Authors: Jotwani R, 175, Palucka AK, Al-Quotub M, Nouri-Shirazi M, Kim J, Bell D, Banchereau J, Cutler CW
2001-10-15;167(8):4693-700.
Species: Human
Sample Types:
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Interleukin-11 induces Th2 polarization of human CD4(+) T cells.
Authors: Curti A, Ratta M, Corinti S, Girolomoni G, Ricci F, Tazzari P, Siena M, Grande A, Fogli M, Tura S, Lemoli RM
Blood, 2001-05-01;97(9):2758-63.
Species: Human
Sample Types: Cell Culture Supernates
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Natural interferon alpha/beta-producing cells link innate and adaptive immunity.
Authors: Kadowaki N, Antonenko S, Lau JY, Liu YJ
J. Exp. Med., 2000-07-17;192(2):219-26.
Species: Human
Sample Types: Cell Culture Supernates
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