Canine/Equine CD44 Antibody Summary
Accession # Q28284
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
![Detection of CD44 antibody in Canine Monocytes antibody by Flow Cytometry. Detection of CD44 antibody in Canine Monocytes antibody by Flow Cytometry.](https://resources.rndsystems.com/images/datasheets/antibody/CD44_MAB5449_Flow_Cytometry_8531.jpg)
Detection of CD44 in Canine Monocytes by Flow Cytometry. Canine blood-derived monocytes were stained with Mouse Anti-Canine/Equine CD44 Monoclonal Antibody (Catalog # MAB5449, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (Catalog # F0101B).
![Detection of CD44 antibody in Equine PBMCs antibody by Flow Cytometry. Detection of CD44 antibody in Equine PBMCs antibody by Flow Cytometry.](https://resources.rndsystems.com/images/datasheets/antibody/CD44_MAB5449_Flow_Cytometry_15103.jpg)
Detection of CD44 in Equine PBMCs by Flow Cytometry. Equine peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Canine/Equine CD44 Monoclonal Antibody (Catalog # MAB5449, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B).
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CD44
Canine CD44 is a ubiquitously expressed 85‑90 kDa transmembrane glycoprotein that binds to hyaluronan and is involved in matrix adhesion, lymphocyte activation, and lymph node homing. The CD44 protein is expressed as a family of molecular isoforms generated by alternate splicing and variable posttranslational modification. Within the N‑terminal invariant portion of the ECD (aa 14‑191), canine CD44 shares 90%, 83%, and 82% identity with human, mouse, and rat CD44, respectively.
Product Datasheets
Citations for Canine/Equine CD44 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
10
Citations: Showing 1 - 10
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Inhibition of protein tyrosine phosphatase improves mitochondrial bioenergetics and dynamics, reduces oxidative stress, and enhances adipogenic differentiation potential in metabolically impaired progenitor stem cells
Authors: Katarzyna Kornicka-Garbowska, Lynda Bourebaba, Michael Röcken, Krzysztof Marycz
Cell Communication and Signaling
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Cladophora glomerata methanolic extract promotes chondrogenic gene expression and cartilage phenotype differentiation in equine adipose-derived mesenchymal stromal stem cells affected by metabolic syndrome
Authors: L Bourebaba, I Michalak, M Baouche, K Kucharczyk, K Marycz
Stem Cell Res Ther, 2019-12-17;10(1):392.
Species: Equine
Sample Types: Whole Cells
Applications: Flow Cytometry -
5-Azacytidine and Resveratrol Enhance Chondrogenic Differentiation of Metabolic Syndrome-Derived Mesenchymal Stem Cells by Modulating Autophagy
Authors: K Marycz, JMI Houston, C Weiss, M Röcken, K Kornicka
Oxid Med Cell Longev, 2019-05-12;2019(0):1523140.
Species: Equine
Sample Types: Whole Cells
Applications: Flow Cytometry -
5-Azacytydine and resveratrol reverse senescence and ageing of adipose stem cells via modulation of mitochondrial dynamics and autophagy
Authors: K Kornicka, J Sz?apka-Ko, A ?mieszek, K Marycz
J. Cell. Mol. Med., 2018-10-28;23(1):237-259.
Species: Equine
Sample Types: Whole Cells
Applications: Flow Cytometry -
Combination of resveratrol and 5-azacytydine improves osteogenesis of metabolic syndrome mesenchymal stem cells
Authors: K Marycz, K Kornicka, JM Irwin-Hous, C Weiss
J. Cell. Mol. Med., 2018-07-12;0(0):.
Species: Equine
Sample Types: Whole Cells
Applications: Flow Cytometry -
Evaluation of Oxidative Stress and Mitophagy during Adipogenic Differentiation of Adipose-Derived Stem Cells Isolated from Equine Metabolic Syndrome (EMS) Horses
Authors: K Marycz, C Weiss, A ?mieszek, K Kornicka
Stem Cells Int, 2018-06-06;2018(0):5340756.
Species: Equine
Sample Types: Whole Cells
Applications: Flow Cytometry -
Macroautophagy and Selective Mitophagy Ameliorate Chondrogenic Differentiation Potential in Adipose Stem Cells of Equine Metabolic Syndrome: New Findings in the Field of Progenitor Cells Differentiation
Authors: K Marycz, K Kornicka, J Grzesiak, A ?mieszek, J Sz?apka
Oxid Med Cell Longev, 2016-12-08;2016(0):3718468.
Applications: Flow Cytometry -
Equine metabolic syndrome impairs adipose stem cells osteogenic differentiation by predominance of autophagy over selective mitophagy
J Cell Mol Med, 2016-09-14;0(0):.
Species: Equine
Sample Types: Whole Cells
Applications: Flow Cytometry -
Canine and Equine Mesenchymal Stem Cells Grown in Serum Free Media Have Altered Immunophenotype.
Authors: Clark K, Kol A, Shahbenderian S, Granick J, Walker N, Borjesson D
Stem Cell Rev, 2016-04-01;12(2):245-56.
Species: Canine
Sample Types: Whole Cells
Applications: Flow Cytometry -
MSI-1436 improves EMS adipose derived progenitor stem cells in the course of adipogenic differentiation through modulation of ER stress, apoptosis, and oxidative stress
Authors: Bourebaba L, Kornicka-Garbowska K, Al Naem M et al
Stem Cell Res Ther
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