Home / PDGF R alpha / Mouse PDGF R alpha Antibody

Mouse PDGF R alpha Antibody

Catalog #: AF1062
136 Citations 9 Reviews Datasheet / COA / SDS
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AF1062
AF1062-SP
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Detection of Mouse PDGF R alpha by Western Blot.
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Citations (136)
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Reviews (9)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse PDGF R alpha Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse PDGF R alpha in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) PDGF R alpha, rhPDGF R beta, and recombinant mouse PDGF R beta is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse PDGF R alpha
Leu25-Glu524 (Asp65Glu, Gly439Ala, Thr440Ala)
Accession # P26618
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
See below
Immunohistochemistry
5-15 µg/mL
See below
Neutralization
Measured by its ability to neutralize PDGF‑AA-induced proliferation in the NR6R‑3T3 mouse fibroblast cell line. The Neutralization Dose (ND50) is typically 0.2 - 1.6 µg/mL in the presence of 250 ng/mL Recombinant Human PDGF‑AA.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Mouse PDGF Ra antibody by Western Blot. View Larger

Detection of Mouse PDGF R alpha by Western Blot. Western blot shows lysates of mouse uterus tissue and mouse lung tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). Specific bands were detected for PDGF Ra at approximately 160-200 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunohistochemistry PDGF Ra antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

PDGF R alpha in Mouse Embryo. PDGF Ra was detected in immersion fixed frozen sections of mouse embryo using Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Immunohistochemistry PDGF Ra antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

PDGF R alpha in Mouse Embryo. PDGF Ra was detected in immersion fixed frozen sections of mouse embryo using 15 µg/mL Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the plasma membrane of mesenchymal cells. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Neutralization Cell Proliferation Induced by PDGF‑AA and Neutralization by Mouse PDGF R alpha Antibody. View Larger

Cell Proliferation Induced by PDGF‑AA and Neutralization by Mouse PDGF R alpha Antibody. Recombinant Human PDGF-AA (Catalog # 221-AA) stimulates proliferation in the NR6R-3T3 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by Resazurin (Catalog # AR002. Proliferation elicited by Recombinant Human PDGF-AA (250 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062). The ND50 is typically 0.2-1.6 µg/mL.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PDGF R alpha

The platelet-derived growth factor (PDGF) family consists of proteins derived from four genes (PDGF-A, -B, -C, and -D) that form disulfide-linked homodimers (PDGF-AA, -BB, -CC, and -DD) and a heterodimer (PDGF-AB) (1, 2). These proteins regulate diverse cellular functions by binding to and inducing the homo- or hetero-dimerization of two receptors (PDGF R alpha  and R beta ). Whereas alpha / alpha homo-dimerization is induced by PDGF-AA, -BB, -CC, and -AB, alpha / beta  hetero-dimerization is induced by PDGF-AB, -BB, -CC, and -DD, and beta / beta  homo-dimerization is induced only by PDGF-BB and -DD (1-4). Both PDGF R alpha  and R beta are members of the class III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for M-CSF, SCF, and Flt-3 ligand. All class III RTKs are characterized by the presence of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular region. Ligand-induced receptor dimerization results in autophosphorylation in trans resulting in the activation of several intracellular signaling pathways that can lead to cell proliferation, cell survival, cytoskeletal rearrangement, and cell migration. Many cell types, including fibroblasts and smooth muscle cells, express both the alpha  and beta  receptors. Others have only the alpha  receptors (oligodendrocyte progenitor cells, mesothelial cells, liver sinusoidal endothelial cells, astrocytes, platelets, and megakaryocytes) or only the  beta receptors (myoblasts, capillary endothelial cells, pericytes, T cells, myeloid hematopoietic cells, and macrophages) (1, 2). Recombinant mouse and human soluble PDGF R beta  bind PDGF with high affinity and are potent PDGF antagonists.

References
  1. Betsholtz, C. et al. (2001) BioEssays 23:494.
  2. Ostman, A. and A.H. Heldin (2001) Advances in Cancer Research 80:1.
  3. Gilbertson, D. et al. (2001) J. Biol. Chem. 276:27406.
  4. LaRochells, W.J. et al. (2001) Nature Cell Biol. 3:517.
Long Name
Platelet-derived Growth Factor Receptor alpha
Entrez Gene IDs
5156 (Human); 18595 (Mouse)
Alternate Names
alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; EC 2.7.10.1; MGC74795; PDGF R alpha; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA/BCR fusion; PDGF-R-alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein; RHEPDGFRA

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Citations for Mouse PDGF R alpha Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

136 Citations: Showing 1 - 10
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  1. Villification of the intestinal epithelium is driven by Foxl1
    Authors: Zhu, G;Lahori, D;Schug, J;Kaestner, KH;
    bioRxiv : the preprint server for biology
    Species: Murine polyomavirus strain A3
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  2. Fibroblasts facilitate lymphatic vessel formation in transplanted heart
    Authors: Gong, H;Wang, T;Sun, X;Zhang, Y;Qiu, Y;Sun, W;Zhang, Y;Teng, P;Hu, Y;Hu, X;Ma, L;Xu, Q;Zhao, H;
    Theranostics
    Species: Murine polyomavirus strain A3, Viral
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  3. Regulation of PDGFR?+ cells and ICC in progesterone-mediated slow colon transit in pregnant mice
    Authors: Lu, C;Luo, H;Wang, Y;Jing, S;Zhao, J;Zou, K;Wu, F;Ying, H;
    Heliyon
    Species: Murine polyomavirus strain A3
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  4. Dispensable regulation of brain development and myelination by Serpina3n
    Authors: Zhu, M;Wang, Y;Park, J;Gong, S;Guo, F;
    bioRxiv : the preprint server for biology
    Species: Murine polyomavirus strain A3
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  5. Obesity differentially effects the somatosensory cortex and striatum of TgF344-AD rats
    Authors: Ahmed, M;Lai, AY;Hill, ME;Ribeiro, JA;Amiraslani, A;McLaurin, J;
    bioRxiv : the preprint server for biology
    Species: S. agalactiae
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  6. Emergent mechanical control of vascular morphogenesis
    Authors: Whisler, J;Shahreza, S;Schlegelmilch, K;Ege, N;Javanmardi, Y;Malandrino, A;Agrawal, A;Fantin, A;Serwinski, B;Azizgolshani, H;Park, C;Shone, V;Demuren, OO;Del Rosario, A;Butty, VL;Holroyd, N;Domart, MC;Hooper, S;Szita, N;Boyer, LA;Walker-Samuel, S;Djordjevic, B;Sheridan, GK;Collinson, L;Calvo, F;Ruhrberg, C;Sahai, E;Kamm, R;Moeendarbary, E;
    Science advances
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  7. Wound infiltrating adipocytes are not myofibroblasts
    Authors: Kalgudde Gopal, S;Dai, R;Stefanska, AM;Ansari, M;Zhao, J;Ramesh, P;Bagnoli, JW;Correa-Gallegos, D;Lin, Y;Christ, S;Angelidis, I;Lupperger, V;Marr, C;Davies, LC;Enard, W;Machens, HG;Schiller, HB;Jiang, D;Rinkevich, Y;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  8. SUMOylation of PDGF receptor ? affects signaling via PLC? and STAT3, and cell proliferation
    Authors: Wang, K;Papadopoulos, N;Hamidi, A;Lennartsson, J;Heldin, CH;
    BMC molecular and cell biology
    Species: African Green Monkey, Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: Immunoprecipitation, IHC, Western Blot
  9. The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
    Authors: A Kolaj, SK Zahr, BS Wang, T Krawec, H Kazan, G Yang, DR Kaplan, FD Miller
    Cell Reports, 2023-03-15;42(3):112242.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  10. Structure, signals, and cellular elements of the mouse gastric mesenchymal niche
    Authors: E Manieri, G Tie, D Seruggia, S Madha, A Maglieri, K Huang, Y Fujiwara, K Zhang, S Orkin, R He, N McCarthy, RA Shivdasani
    bioRxiv : the preprint server for biology, 2023-02-24;0(0):.
    Species: Mouse
    Sample Types: Organoid
    Applications: IHC
  11. Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner
    Authors: K Hoeft, GJL Schaefer, H Kim, D Schumacher, T Bleckwehl, Q Long, BM Klinkhamme, F Peisker, L Koch, J Nagai, M Halder, S Ziegler, E Liehn, C Kuppe, J Kranz, S Menzel, I Costa, A Wahida, P Boor, RK Schneider, S Hayat, R Kramann
    Cell Reports, 2023-02-17;42(2):112131.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  12. Angiogenesis precedes myogenesis during regeneration following biopsy injury of skeletal muscle
    Authors: NL Jacobsen, AB Morton, SS Segal
    Skeletal Muscle, 2023-02-14;13(1):3.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  13. Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
    Authors: ME Mohr, S Li, AM Trouten, RA Stairley, PL Roddy, C Liu, M Zhang, HM Sucov, G Tao
    bioRxiv : the preprint server for biology, 2023-02-08;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  14. Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress
    Authors: Z Li, K Chen, Q Shao, H Lu, X Zhang, Y Pu, X Sun, H He, L Cao
    Journal of Neuroinflammation, 2023-01-30;20(1):16.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  15. Discoidin domain receptor 2 regulates aberrant mesenchymal lineage cell fate and matrix organization
    Authors: CA Pagani, AC Bancroft, RJ Tower, N Livingston, Y Sun, JY Hong, RN Kent, AL Strong, JH Nunez, JMR Medrano, N Patel, BA Nanes, KM Dean, Z Li, C Ge, BM Baker, AW James, SJ Weiss, RT Franceschi, B Levi
    Science Advances, 2022-12-21;8(51):eabq6152.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  16. Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke
    Authors: X Hong, Y Jian, S Ding, J Zhou, X Zheng, H Zhang, B Zhou, C Zhuang, J Wan, X Tong
    EBioMedicine, 2022-12-15;87(0):104406.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  17. Effects of MgSO4 Alone or Associated with 4-PBA on Behavior and White Matter Integrity in a Mouse Model of Cerebral Palsy: A Sex- and Time-Dependent Study
    Authors: L Legouez, B Le Dieu-Lu, S Feillet, G Riou, M Yeddou, T Plouchart, N Dourmap, MA Le Ray, S Marret, BJ Gonzalez, C Cleren
    International Journal of Molecular Sciences, 2022-12-15;23(24):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  18. DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal
    Authors: P Cattaneo, MGB Hayes, N Baumgarten, D Hecker, S Peruzzo, GS Aslan, P Kunderfran, V Larcher, L Zhang, R Contu, G Fonseca, S Spinozzi, J Chen, G Condorelli, S Dimmeler, MH Schulz, S Heinz, N Guimarães-, SM Evans
    Nature Communications, 2022-12-02;13(1):7444.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  19. Ultrastructural characteristics of oligodendrocyte precursor cells in the early postnatal mouse optic nerve observed by serial block-face scanning electron microscopy
    Authors: K Ono, H Gotoh, T Nomura, T Morita, O Baba, M Matsumoto, S Saitoh, N Ohno
    PLoS ONE, 2022-12-01;17(12):e0278118.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  20. KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF
    Authors: C Bernhardt, E Sock, F Fröb, S Hillgärtne, M Nemer, M Wegner
    Nucleic Acids Research, 2022-11-11;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  21. CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging
    Authors: T Kaya, N Mattugini, L Liu, H Ji, L Cantuti-Ca, J Wu, M Schifferer, J Groh, R Martini, S Besson-Gir, S Kaji, A Liesz, O Gokce, M Simons
    Nature Neuroscience, 2022-10-24;25(11):1446-1457.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  22. Vaccination-based immunotherapy to target profibrotic cells in liver and lung
    Authors: M Sobecki, J Chen, E Krzywinska, S Nagarajan, Z Fan, E Nelius, JM Monné Rodr, F Seehusen, A Hussein, G Moschini, EY Hajam, R Kiran, D Gotthardt, J Debbache, C Badoual, T Sato, T Isagawa, N Takeda, C Tanchot, E Tartour, A Weber, S Werner, J Loffing, L Sommer, V Sexl, C Münz, C Feghali-Bo, E Pachera, O Distler, J Snedeker, C Jamora, C Stockmann
    Cell Stem Cell, 2022-09-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC
  23. Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain
    Authors: RM Beiter, C Rivet-Noor, AR Merchak, R Bai, DM Johanson, E Slogar, K Sol-Church, CC Overall, A Gaultier
    Scientific Reports, 2022-07-28;12(1):12921.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  24. Transcriptome profiling of subepithelial PDGFRalpha cells in colonic mucosa reveals several cell-selective markers
    Authors: SE Ha, B Jin, BG Jorgensen, H Zogg, L Wei, R Singh, C Park, M Kurahashi, S Kim, G Baek, SM Poudrier, MY Lee, KM Sanders, S Ro
    PLoS ONE, 2022-05-13;17(5):e0261743.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  25. PDGFRalpha-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms
    Authors: JM Jacob, SE Di Carlo, I Stzepourgi, A Lepelletie, PD Ndiaye, H Varet, R Legendre, E Kornobis, A Benabid, G Nigro, L Peduto
    Cell Stem Cell, 2022-05-05;29(5):856-868.e5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  26. Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination
    Authors: S Ghorbani, E Jelinek, R Jain, B Buehner, C Li, BM Lozinski, S Sarkar, DK Kaushik, Y Dong, TN Wight, S Karimi-Abd, GJ Schenk, EM Strijbis, J Geurts, P Zhang, CC Ling, VW Yong
    Nature Communications, 2022-05-04;13(1):2445.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  27. Maladaptive myelination promotes generalized epilepsy progression
    Authors: JK Knowles, H Xu, C Soane, A Batra, T Saucedo, E Frost, LT Tam, D Fraga, L Ni, K Villar, S Talmi, JR Huguenard, M Monje
    Nature Neuroscience, 2022-05-02;25(5):596-606.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  28. An estrogen-sensitive fibroblast population drives abdominal muscle fibrosis in an inguinal hernia mouse model
    Authors: T Potluri, MJ Taylor, JJ Stulberg, RL Lieber, H Zhao, SE Bulun
    JCI Insight, 2022-04-19;7(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  29. Platelet-Derived PDGFB Promotes Recruitment of Cancer-Associated Fibroblasts, Deposition of Extracellular Matrix and Tgfbeta Signaling in the Tumor Microenvironment
    Authors: Y Zhang, E Manouchehr, M Herre, J Cedervall, Q Qiao, Z Miao, A Hamidi, L Hellman, M Kamali-Mog, AK Olsson
    Cancers, 2022-04-12;14(8):.
    Species: Mouse
    Sample Types: Whole Cells
  30. Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation
    Authors: S Pantasis, J Friemel, SM Brütsch, Z Hu, S Krautbauer, G Liebisch, J Dengjel, A Weber, S Werner, MR Bordoli
    Journal of Cell Science, 2022-04-12;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  31. Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing
    Authors: XR Ma, X Zhu, Y Xiao, HM Gu, SS Zheng, L Li, F Wang, ZJ Dong, DX Wang, Y Wu, C Yang, W Jiang, K Yao, Y Yin, Y Zhang, C Peng, L Gao, Z Meng, Z Hu, C Liu, L Li, HZ Chen, Y Shu, Z Ju, JW Zhao
    Nature Communications, 2022-03-09;13(1):1225.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IF
  32. Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain
    Authors: A Fernández-, P Lu, AC Geraghty, E Song, MH Lee, J Wood, B Yalç?n, KR Taylor, S Dutton, L Acosta-Alv, L Ni, D Contreras-, JR Gehlhausen, J Klein, C Lucas, T Mao, J Silva, MA Peña-Herná, A Tabachniko, T Takahashi, L Tabacof, J Tosto-Manc, E Breyman, A Kontorovic, D McCarthy, M Quezado, M Hefti, D Perl, R Folkerth, D Putrino, A Nath, A Iwasaki, M Monje
    bioRxiv : the preprint server for biology, 2022-01-10;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  33. Involvement of PAR2 in platelet-derived growth factor receptor-alpha-positive cell proliferation in the colon of diabetic mice
    Authors: YJ Li, JP Ao, X Huang, HL Lu, HY Fu, NN Song, WX Xu, J Chen
    Physiological Reports, 2021-11-01;9(21):e15099.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  34. Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling
    Authors: V Reyes Nico, JM Allaire, AB Alfonso, D Pupo Gómez, V Pomerleau, V Giroux, F Boudreau, N Perreault
    Cells, 2021-10-29;10(11):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  35. Regulation of intestinal immunity and tissue repair by enteric glia
    Authors: F Progatzky, M Shapiro, SH Chng, B Garcia-Cas, CH Classon, S Sevgi, A Laddach, AC Bon-Frauch, R Lasrado, M Rahim, EM Amaniti, S Boeing, K Shah, LJ Entwistle, A Suárez-Bon, MS Wilson, B Stockinger, V Pachnis
    Nature, 2021-10-20;599(7883):125-130.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  36. Spatial gene expression maps of the intestinal lymphoid follicle and associated epithelium identify zonated expression programs
    Authors: N Cohen, H Massalha, S Ben-Moshe, A Egozi, M Rozenberg, K Bahar Halp, S Itzkovitz
    PloS Biology, 2021-10-11;19(10):e3001214.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IF
  37. PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
    Authors: Y Wang, Y Zhang, S Zhang, B Kim, VL Hull, J Xu, P Prabhu, M Gregory, V Martinez-C, X Zhan, W Deng, F Guo
    Cell Reports, 2021-10-05;37(1):109695.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  38. NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety
    Authors: X Zhang, Y Liu, X Hong, X Li, CK Meshul, C Moore, Y Yang, Y Han, WG Li, X Qi, H Lou, S Duan, TL Xu, X Tong
    Nature Communications, 2021-09-30;12(1):5740.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  39. Sensitive timing of undifferentiation in oligodendrocyte progenitor cells and their enhanced maturation in primary visual cortex of binocularly enucleated mice
    Authors: H Shin, HD Kawai
    PLoS ONE, 2021-09-17;16(9):e0257395.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  40. Microglial ASD-related genes are involved in oligodendrocyte differentiation
    Authors: Y Takanezawa, S Tanabe, D Kato, R Ozeki, M Komoda, T Suzuki, H Baba, R Muramatsu
    Scientific Reports, 2021-09-08;11(1):17825.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  41. Molecular and functional characterization of detrusor PDGFRalpha positive cells in spinal cord injury-induced detrusor overactivity
    Authors: K Lee, SO Park, PC Choi, SB Ryoo, H Lee, LE Peri, T Zhou, RD Corrigan, AC Yanez, SB Moon, BA Perrino, KM Sanders, SD Koh
    Scientific Reports, 2021-08-11;11(1):16268.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  42. Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation
    Authors: L Cordero-Es, AM Dowbaj, TN Kohler, B Strauss, O Sarlidou, G Belenguer, C Pacini, NP Martins, R Dobie, JR Wilson-Kan, R Butler, N Prior, P Serup, F Jug, NC Henderson, F Hollfelder, M Huch
    Cell Stem Cell, 2021-08-02;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  43. Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages
    Authors: I De, V Maklakova, S Litscher, MM Boyd, LC Klemm, Z Wang, C Kendziorsk, LS Collier
    Journal of Neuroinflammation, 2021-07-19;18(1):162.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  44. Regional specialization and fate specification of bone stromal cells in skeletal development
    Authors: KK Sivaraj, HW Jeong, B Dharmaling, D Zeuschner, S Adams, M Potente, RH Adams
    Cell Reports, 2021-07-13;36(2):109352.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  45. Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality
    Authors: SC Schüler, JM Kirkpatric, M Schmidt, D Santinha, P Koch, S Di Sanzo, E Cirri, M Hemberg, A Ori, J von Maltza
    Cell Reports, 2021-06-08;35(10):109223.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  46. Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle
    Authors: A Waisman, AM Norris, M Elías Cost, D Kopinke
    Scientific Reports, 2021-06-03;11(1):11793.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  47. NF1 mutation drives neuronal�activity-dependent initiation of optic glioma
    Authors: Y Pan, JD Hysinger, T Barron, NF Schindler, O Cobb, X Guo, B Yalç?n, C Anastasaki, SB Mulinyawe, A Ponnuswami, S Scheaffer, Y Ma, KC Chang, X Xia, JA Toonen, JJ Lennon, EM Gibson, JR Huguenard, LM Liau, JL Goldberg, M Monje, DH Gutmann
    Nature, 2021-05-26;594(7862):277-282.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  48. The Impact of Fixation on the Detection of Oligodendrocyte Precursor Cell Morphology and Vascular Associations
    Authors: F Pfeiffer, A Sherafat, A Nishiyama
    Cells, 2021-05-24;10(6):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  49. PDGF-PDGFR network differentially regulates the fate, migration, proliferation, and cell cycle progression of myogenic cells
    Authors: O Contreras, A Córdova-Ca, E Brandan
    Cellular Signalling, 2021-05-08;84(0):110036.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC/IF, Western Blot
  50. Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells
    Authors: MN Wosczyna, EE Perez Carb, MW Wagner, S Paredes, CT Konishi, L Liu, TT Wang, RA Walsh, Q Gan, CS Morrissey, TA Rando
    Cell Stem Cell, 2021-05-03;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC
  51. Contribution of PDGFR&alpha-positive cells in maintenance and injury responses in mouse large vessels
    Authors: K Kimura, K Ramirez, TAV Nguyen, Y Yamashiro, A Sada, H Yanagisawa
    Scientific Reports, 2021-04-21;11(1):8683.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  52. Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
    Authors: W Mu, S Li, J Xu, X Guo, H Wu, Z Chen, L Qiao, G Helfer, F Lu, C Liu, QF Wu
    Nature Communications, 2021-04-16;12(1):2288.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  53. Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy
    Authors: L Mészáros, MJ Riemenschn, H Gassner, F Marxreiter, S von Hörste, A Hoffmann, J Winkler
    Acta neuropathologica communications, 2021-04-14;9(1):68.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  54. Identification of PDGFR&alpha-positive interstitial cells in the distal segment of the murine vas deferens
    Authors: T Hiroshige, KI Uemura, S Hirashima, K Hino, A Togo, K Ohta, T Igawa, KI Nakamura
    Scientific Reports, 2021-04-06;11(1):7553.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  55. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence
    Authors: S Choi, B Zhang, S Ma, M Gonzalez-C, D Stein, X Jin, ST Kim, YL Kang, A Besnard, A Rezza, L Grisanti, JD Buenrostro, M Rendl, M Nahrendorf, A Sahay, YC Hsu
    Nature, 2021-03-31;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  56. PDGFR&alpha: Expression and Function during Mitral Valve Morphogenesis
    Authors: K Moore, D Fulmer, L Guo, N Koren, J Glover, R Moore, C Gensemer, T Beck, J Morningsta, R Stairley, RA Norris
    Journal of cardiovascular development and disease, 2021-03-13;8(3):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  57. Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis
    Authors: D Yamakawa, D Katoh, K Kasahara, T Shiromizu, M Matsuyama, C Matsuda, Y Maeno, M Watanabe, Y Nishimura, M Inagaki
    Cell Reports, 2021-03-09;34(10):108817.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  58. Direct reprogramming of oligodendrocyte precursor cells into GABAergic inhibitory neurons by a single homeodomain transcription factor Dlx2
    Authors: LL Boshans, H Soh, WM Wood, TM Nolan, II Mandoiu, Y Yanagawa, AV Tzingounis, A Nishiyama
    Scientific Reports, 2021-02-11;11(1):3552.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  59. SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors
    Authors: G Giuliani, S Vumbaca, C Fuoco, C Gargioli, E Giorda, G Massacci, A Palma, A Reggio, F Riccio, M Rosina, M Vinci, L Castagnoli, G Cesareni
    Cell Death & Disease, 2021-01-25;12(1):122.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  60. Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain
    Authors: CL Cullen, RE Pepper, MT Clutterbuc, KA Pitman, V Oorschot, L Auderset, AD Tang, G Ramm, B Emery, J Rodger, RB Jolivet, KM Young
    Cell Reports, 2021-01-19;34(3):108641.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  61. Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis
    Authors: MD Brügger, T Valenta, H Fazilaty, G Hausmann, K Basler
    PloS Biology, 2020-12-11;18(12):e3001032.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  62. Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
    Authors: EM Floriddia, T Lourenço, S Zhang, D van Brugge, MM Hilscher, P Kukanja, JP Gonçalves, M Alt?nkök, C Yokota, E Llorens-Bo, SB Mulinyawe, M Grãos, LO Sun, J Frisén, M Nilsson, G Castelo-Br
    Nat Commun, 2020-11-17;11(1):5860.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  63. Neuronal activity-dependent myelin repair promotes motor function recovery after contusion spinal cord injury
    Authors: M Luo, Y Yin, D Li, W Tang, Y Liu, L Pan, L Yu, B Tan
    Brain Res Bull, 2020-11-14;166(0):73-81.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  64. Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin
    Authors: D Jiang, S Christ, D Correa-Gal, P Ramesh, S Kalgudde G, J Wannemache, CH Mayr, V Lupperger, Q Yu, H Ye, M Mück-Häusl, V Rajendran, L Wan, J Liu, U Mirastschi, T Volz, C Marr, HB Schiller, Y Rinkevich
    Nat Commun, 2020-11-06;11(1):5653.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  65. PDGFRA in vascular adventitial MSCs promotes neointima formation in arteriovenous fistula in chronic kidney disease
    Authors: K Song, Y Qing, Q Guo, EK Peden, C Chen, WE Mitch, L Truong, J Cheng
    JCI Insight, 2020-11-05;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: ICC, IHC, Western Blot
  66. Retinoic acid signalling in fibro/adipogenic progenitors robustly enhances muscle regeneration
    Authors: L Zhao, JS Son, B Wang, Q Tian, Y Chen, X Liu, JM de Avila, MJ Zhu, M Du
    EBioMedicine, 2020-09-24;60(0):103020.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  67. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi
    Authors: SP Hong, MJ Yang, H Cho, I Park, H Bae, K Choe, SH Suh, RH Adams, K Alitalo, D Lim, GY Koh
    Nat Commun, 2020-08-14;11(1):4102.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  68. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing
    Authors: S Abbasi, S Sinha, E Labit, NL Rosin, G Yoon, W Rahmani, A Jaffer, N Sharma, A Hagner, P Shah, R Arora, J Yoon, A Islam, A Uchida, CK Chang, JA Stratton, RW Scott, FMV Rossi, TM Underhill, J Biernaskie
    Cell Stem Cell, 2020-08-04;27(3):396-412.e6.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  69. Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases
    Authors: AF Asega, MC Menezes, D Trevisan-S, D Cajado-Car, L Bertholim, AK Oliveira, A Zelanis, SMT Serrano
    Sci Rep, 2020-07-31;10(1):12912.
    Species: Mouse
    Sample Types: Cell Lysates, Tissue Homogenates
    Applications: Western Blot
  70. BCAS1-positive immature oligodendrocytes are affected by the &alpha-synuclein-induced pathology of multiple system atrophy
    Authors: S Kaji, T Maki, J Ueda, T Ishimoto, Y Inoue, K Yasuda, M Sawamura, R Hikawa, T Ayaki, H Yamakado, R Takahashi
    Acta Neuropathol Commun, 2020-07-29;8(1):120.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  71. The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination
    Authors: A Pu, MK Mishra, Y Dong, S Ghorbaniga, EL Stephenson, KS Rawji, C Silva, H Kitagawa, S Sawcer, VW Yong
    J Neuroinflammation, 2020-07-23;17(1):220.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  72. TGF-beta-driven downregulation of the transcription factor TCF7L2 affects Wnt/beta-catenin signaling in PDGFRalpha+ fibroblasts
    Authors: O Contreras, H Soliman, M Theret, FMV Rossi, E Brandan
    J. Cell. Sci., 2020-06-19;133(12):.
    Species: Mouse, Transgenic Mouse
    Sample Types: Cell Lysates, Tissue Homogenates
    Applications: Western Blot
  73. Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth
    Authors: S Davidson, M Efremova, A Riedel, B Mahata, J Pramanik, J Huuhtanen, G Kar, R Vento-Torm, T Hagai, X Chen, MA Haniffa, JD Shields, SA Teichmann
    Cell Rep, 2020-05-19;31(7):107628.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Flow Cytometry
  74. Embryonic microglia influence developing hypothalamic glial populations
    Authors: CM Marsters, D Nesan, R Far, N Klenin, QJ Pittman, DM Kurrasch
    J Neuroinflammation, 2020-05-06;17(1):146.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  75. Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles
    Authors: J Camps, N Breuls, A Sifrim, N Giarratana, M Corvelyn, L Danti, H Grosemans, S Vanuytven, I Thiry, M Belicchi, M Meregalli, K Platko, ME MacDonald, RC Austin, R Gijsbers, G Cossu, Y Torrente, T Voet, M Sampaolesi
    Cell Rep, 2020-05-05;31(5):107597.
    Species: Human
    Sample Types: Whole Cells
  76. Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates
    Authors: N Micali, SK Kim, M Diaz-Busta, G Stein-O'Br, S Seo, JH Shin, BG Rash, S Ma, Y Wang, NA Olivares, JI Arellano, KR Maynard, EJ Fertig, AJ Cross, RW Bürli, NJ Brandon, DR Weinberger, JG Chenoweth, DJ Hoeppner, N Sestan, P Rakic, C Colantuoni, RD McKay
    Cell Rep, 2020-05-05;31(5):107599.
    Species: Human
    Sample Types:
    Applications: IF
  77. Lgr5+�telocytes are a signaling source at the intestinal villus tip
    Authors: K Bahar Halp, H Massalha, RK Zwick, AE Moor, D Castillo-A, M Rozenberg, L Farack, A Egozi, DR Miller, I Averbukh, Y Harnik, N Weinberg-C, FJ de Sauvage, I Amit, OD Klein, M Shoshkes-C, S Itzkovitz
    Nat Commun, 2020-04-22;11(1):1936.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  78. Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient
    Authors: N McCarthy, E Manieri, EE Storm, A Saadatpour, AM Luoma, VN Kapoor, S Madha, LT Gaynor, C Cox, S Keerthivas, K Wucherpfen, GC Yuan, FJ de Sauvage, SJ Turley, RA Shivdasani
    Cell Stem Cell, 2020-02-20;0(0):.
    Species: Mouse
    Sample Types: Tissue
    Applications: IHC
  79. TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung
    Authors: I Wojahn, TH Lüdtke, VM Christoffe, MO Trowe, A Kispert
    Respir. Res., 2019-12-23;20(1):292.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  80. TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation
    Authors: A Grund, M Szaroszyk, M Korf-Kling, M Malek Moha, FA Trogisch, U Schrameck, A Gigina, C Tiedje, M Gaestel, T Kraft, J Hegermann, S Batkai, T Thum, A Perrot, CD Remedios, E Riechert, M Völkers, S Doroudgar, A Jungmann, R Bauer, X Yin, M Mayr, KC Wollert, A Pich, H Xiao, HA Katus, J Bauersachs, OJ Müller, J Heineke
    EMBO Mol Med, 2019-08-30;0(0):e10018.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  81. Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice
    Authors: X Zhang, X Wang, H Yin, L Zhang, A Feng, QX Zhang, Y Lin, B Bao, LL Hernandez, GP Shi, J Liu
    Cell Rep, 2019-07-16;28(3):792-803.e4.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  82. Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
    Authors: SS Welc, I Flores, M Wehling-He, J Ramos, Y Wang, C Bertoni, JG Tidball
    Nat Commun, 2019-06-26;10(1):2788.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  83. Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B
    Authors: MW Hogarth, A Defour, C Lazarski, E Gallardo, JD Manera, TA Partridge, K Nagaraju, JK Jaiswal
    Nat Commun, 2019-06-03;10(1):2430.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  84. Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle
    Authors: MN Wosczyna, CT Konishi, EE Perez Carb, TT Wang, RA Walsh, Q Gan, MW Wagner, TA Rando
    Cell Rep, 2019-05-14;27(7):2029-2035.e5.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC frozen fixed
  85. In Situ Modification of Tissue Stem and Progenitor Cell Genomes
    Authors: JM Goldstein, M Tabebordba, K Zhu, LD Wang, KA Messemer, B Peacker, S Ashrafi Ka, M Gonzalez-C, Y Shwartz, JKW Cheng, R Xiao, T Barungi, C Albright, YC Hsu, LH Vandenberg, AJ Wagers
    Cell Rep, 2019-04-23;27(4):1254-1264.e7.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  86. Myelin repair stimulated by CNS-selective thyroid hormone action
    Authors: MD Hartley, T Banerji, IJ Tagge, LL Kirkemo, P Chaudhary, E Calkins, D Galipeau, MD Shokat, MJ DeBell, S Van Leuven, H Miller, G Marracci, E Pocius, T Banerji, SJ Ferrara, JM Meinig, B Emery, D Bourdette, TS Scanlan
    JCI Insight, 2019-04-18;4(8):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  87. PDGFR?+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland
    Authors: PA Joshi, PD Waterhouse, K Kasaian, H Fang, O Gulyaeva, HS Sul, PC Boutros, R Khokha
    Nat Commun, 2019-04-15;10(1):1760.
    Species: Mouse
    Sample Types: Whole Tissues
    Applications: IHC
  88. Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration
    Authors: X Han, Y Wang, W Pu, X Huang, L Qiu, Y Li, W Yu, H Zhao, X Liu, L He, L Zhang, Y Ji, J Lu, KO Lui, B Zhou
    Stem Cell Reports, 2019-02-14;12(3):624-638.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  89. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds
    Authors: CF Guerrero-J, PH Dedhia, S Jin, R Ruiz-Vega, D Ma, Y Liu, K Yamaga, O Shestova, DL Gay, Z Yang, K Kessenbroc, Q Nie, WS Pear, G Cotsarelis, MV Plikus
    Nat Commun, 2019-02-08;10(1):650.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  90. Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors
    Authors: L Lukjanenko, S Karaz, P Stuelsatz, U Gurriaran-, J Michaud, G Dammone, F Sizzano, O Mashinchia, S Ancel, E Migliavacc, S Liot, G Jacot, S Metairon, F Raymond, P Descombes, A Palini, B Chazaud, MA Rudnicki, CF Bentzinger, JN Feige
    Cell Stem Cell, 2019-01-24;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  91. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
    Authors: D Aran, AP Looney, L Liu, E Wu, V Fong, A Hsu, S Chak, RP Naikawadi, PJ Wolters, AR Abate, AJ Butte, M Bhattachar
    Nat. Immunol., 2019-01-14;20(2):163-172.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  92. Profiling proliferative cells and their progeny in damaged murine hearts
    Authors: K Kretzschma, Y Post, M Bannier-Hé, A Mattiotti, J Drost, O Basak, VSW Li, M van den Bo, QD Gunst, D Versteeg, L Kooijman, S van der El, JH van Es, E van Rooij, MJB van den Ho, H Clevers
    Proc. Natl. Acad. Sci. U.S.A., 2018-12-07;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr, IHC-P
  93. Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome
    Authors: S Oishi, D Harkins, ND Kurniawan, M Kasherman, L Harris, O Zalucki, RM Gronostajs, THJ Burne, M Piper
    EBioMedicine, 2018-11-29;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  94. Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration
    Authors: MJ Carr, JS Toma, APW Johnston, PE Steadman, SA Yuzwa, N Mahmud, PW Frankland, DR Kaplan, FD Miller
    Cell Stem Cell, 2018-11-29;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  95. AMPK Activation Regulates LTBP4-Dependent TGF-?1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy
    Authors: G Juban, M Saclier, H Yacoub-You, A Kernou, L Arnold, C Boisson, S Ben Larbi, M Magnan, S Cuvellier, M Théret, BJ Petrof, I Desguerre, J Gondin, R Mounier, B Chazaud
    Cell Rep, 2018-11-20;25(8):2163-2176.e6.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  96. Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1?
    Authors: SK Jensen, NJ Michaels, S Ilyntskyy, MB Keough, O Kovalchuk, VW Yong
    Cell Rep, 2018-09-18;24(12):3167-3179.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  97. Pulmonary pericytes regulate lung morphogenesis
    Authors: K Kato, R Diéguez-Hu, DY Park, SP Hong, S Kato-Azuma, S Adams, M Stehling, B Trappmann, JL Wrana, GY Koh, RH Adams
    Nat Commun, 2018-06-22;9(1):2448.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  98. Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
    Authors: SN Kim, S Akindehin, HJ Kwon, YH Son, A Saha, YS Jung, JK Seong, KM Lim, JH Sung, KR Maddipati, YH Lee
    Sci Rep, 2018-06-11;8(1):8856.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  99. Perfect chronic skeletal muscle regeneration in adult spiny mice, Acomys cahirinus
    Authors: M Maden, JO Brant, A Rubiano, AGW Sandoval, C Simmons, R Mitchell, H Collin-Hoo, J Jacobson, S Omairi, K Patel
    Sci Rep, 2018-06-11;8(1):8920.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  100. Myelination of the developing lateral olfactory tract and anterior commissure
    Authors: LN Collins, DL Hill, PC Brunjes
    J. Comp. Neurol., 2018-04-26;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  101. B-1a lymphocytes promote oligodendrogenesis during brain development
    Authors: S Tanabe, T Yamashita
    Nat. Neurosci., 2018-03-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  102. Role of P2XReceptor in Mouse Voiding Function
    Authors: W Yu, WG Hill, SC Robson, ML Zeidel
    Sci Rep, 2018-01-30;8(1):1838.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  103. Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner
    Authors: S Mitew, I Gobius, LR Fenlon, SJ McDougall, D Hawkes, YL Xing, H Bujalka, AL Gundlach, LJ Richards, TJ Kilpatrick, TD Merson, B Emery
    Nat Commun, 2018-01-22;9(1):306.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  104. Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion
    Authors: S Begolly, JA Olschowka, T Love, JP Williams, MK O'Banion
    Glia, 2017-12-30;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  105. Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination
    Authors: Y Chen, W Zhen, T Guo, Y Zhao, A Liu, JP Rubio, D Krull, JC Richardson, H Lu, R Wang
    PLoS ONE, 2017-12-18;12(12):e0189380.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  106. Colonic PDGFR? Overexpression Accompanied Forkhead Transcription Factor FOXO3 Up-Regulation in STZ-Induced Diabetic Mice
    Authors: H Lu, C Zhang, N Song, C Lu, L Tong, X Huang, YC Kim, J Chen, W Xu
    Cell. Physiol. Biochem., 2017-08-28;43(1):158-171.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  107. Transcriptome analysis of PDGFR?+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFR?+ cell hyperplasia
    Authors: SE Ha, MY Lee, M Kurahashi, L Wei, BG Jorgensen, C Park, PJ Park, D Redelman, KC Sasse, LS Becker, KM Sanders, S Ro
    PLoS ONE, 2017-08-14;12(8):e0182265.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  108. Pdgfr? functions in endothelial-derived cells to regulate neural crest cells and development of the great arteries
    Authors: H Aghajanian, YK Cho, NW Rizer, Q Wang, L Li, K Degenhardt, R Jain
    Dis Model Mech, 2017-07-14;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  109. ALS skeletal muscle shows enhanced TGF-? signaling, fibrosis and induction of fibro/adipogenic progenitor markers
    Authors: D Gonzalez, O Contreras, DL Rebolledo, JP Espinoza, B van Zunder, E Brandan
    PLoS ONE, 2017-05-16;12(5):e0177649.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: IHC, Western Blot
  110. Physiologically activated mammary fibroblasts promote postpartum mammary cancer
    Authors: Q Guo, J Minnier, J Burchard, K Chiotti, P Spellman, P Schedin
    JCI Insight, 2017-03-23;2(6):e89206.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  111. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In�Vivo
    Authors: N Guimar?es-, P Cattaneo, Y Sun, T Moore-Morr, Y Gu, ND Dalton, E Rockenstei, E Masliah, KL Peterson, WB Stallcup, J Chen, SM Evans
    Cell Stem Cell, 2017-01-19;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  112. Leptin sustains spontaneous remyelination in the adult central nervous system
    Authors: K Matoba, R Muramatsu, T Yamashita
    Sci Rep, 2017-01-16;7(0):40397.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  113. Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos
    Sci Rep, 2016-12-19;6(0):39457.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  114. Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation
    Cell Rep, 2016-11-22;17(9):2312-2325.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  115. Real-time and Non-invasive Monitoring of Embryonic Stem Cell Survival during the Development of Embryoid Bodies with Smart Nanosensor
    Authors: Dong-An Wang
    Acta Biomater, 2016-11-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  116. USP9X deletion elevates the density of oligodendrocytes within the postnatal dentate gyrus
    Authors: Michael Piper
    Neurogenesis (Austin), 2016-09-30;3(1):e1235524.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  117. Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development
    Authors: K Noda, M Kitami, K Kitami, M Kaku, Y Komatsu
    Proc Natl Acad Sci USA, 2016-04-26;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates, Whole Cells
    Applications: IHC, Western Blot
  118. Spatio-Temporal Patterns of Demyelination and Remyelination in the Cuprizone Mouse Model
    Authors: I Tagge, A O'Connor, P Chaudhary, J Pollaro, Y Berlow, M Chalupsky, D Bourdette, R Woltjer, M Johnson, W Rooney
    PLoS ONE, 2016-04-07;11(4):e0152480.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  119. AHNAK deficiency promotes browning and lipolysis in mice via increased responsiveness to ?-adrenergic signalling
    Authors: JH Shin, SH Lee, YN Kim, IY Kim, YJ Kim, DS Kyeong, HJ Lim, SY Cho, J Choi, YJ Wi, JH Choi, YS Yoon, YS Bae, JK Seong
    Sci Rep, 2016-03-18;6(0):23426.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  120. Double minute amplification of mutant PDGF receptor alpha in a mouse glioma model.
    Authors: Zou H, Feng R, Huang Y, Tripodi J, Najfeld V, Tsankova N, Jahanshahi M, Olson L, Soriano P, Friedel R
    Sci Rep, 2015-02-16;5(0):8468.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  121. Transplanted bone marrow-derived circulating PDGFRalpha+ cells restore type VII collagen in recessive dystrophic epidermolysis bullosa mouse skin graft.
    Authors: Iinuma S, Aikawa E, Tamai K, Fujita R, Kikuchi Y, Chino T, Kikuta J, McGrath J, Uitto J, Ishii M, Iizuka H, Kaneda Y
    J Immunol, 2015-01-19;194(4):1996-2003.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  122. Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development.
    Authors: Daquinag, A C, Tseng, C, Salameh, A, Zhang, Y, Amaya-Manzanares, F, Dadbin, A, Florez, F, Xu, Y, Tong, Q, Kolonin, M G
    Cell Death Differ, 2014-10-24;22(2):351-63.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  123. Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling.
    Authors: Pinto, Mauricio, Dye, Wendy W, Jacobsen, Britta M, Horwitz, Kathryn
    BMC Cancer, 2014-10-01;14(0):735.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  124. Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells.
    Authors: Ettle B, Reiprich S, Deusser J, Schlachetzki J, Xiang W, Prots I, Masliah E, Winner B, Wegner M, Winkler J
    Mol Cell Neurosci, 2014-07-11;62(0):68-78.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC, Western Blot
  125. Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.
    Authors: Moore-Morris T, Guimaraes-Camboa N, Banerjee I, Zambon A, Kisseleva T, Velayoudon A, Stallcup W, Gu Y, Dalton N, Cedenilla M, Gomez-Amaro R, Zhou B, Brenner D, Peterson K, Chen J, Evans S
    J Clin Invest, 2014-06-17;124(7):2921-34.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  126. Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
    Authors: Gibson, Erin M, Purger, David, Mount, Christop, Goldstein, Andrea K, Lin, Grant L, Wood, Lauren S, Inema, Ingrid, Miller, Sarah E, Bieri, Gregor, Zuchero, J Bradle, Barres, Ben A, Woo, Pamelyn, Vogel, Hannes, Monje, Michelle
    Science, 2014-04-10;344(6183):1252304.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  127. Nitric oxide controls fat deposition in dystrophic skeletal muscle by regulating fibro-adipogenic precursor differentiation.
    Authors: Cordani N, Pisa V, Pozzi L, Sciorati C, Clementi E
    Stem Cells, 2014-04-01;32(4):874-85.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  128. Hypoxia inducible factor-2alpha regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors.
    Authors: Duan L, Takeda K, Fong G
    PLoS ONE, 2014-01-27;9(1):e84736.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  129. Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
    Authors: Fan J, Ponferrada V, Sato T, Vemaraju S, Fruttiger M, Gerhardt H, Ferrara N, Lang R
    Development, 2013-12-18;141(2):448-59.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  130. Distinct fibroblast lineages determine dermal architecture in skin development and repair.
    Authors: Driskell R, Lichtenberger B, Hoste E, Kretzschmar K, Simons B, Charalambous M, Ferron S, Herault Y, Pavlovic G, Ferguson-Smith A, Watt F
    Nature, 2013-12-12;504(7479):277-81.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  131. Abnormal development of NG2+PDGFR-alpha+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model.
    Authors: Carter C, Vogel T, Zhang Q, Seo S, Swiderski R, Moninger T, Cassell M, Thedens D, Keppler-Noreuil K, Nopoulos P, Nishimura D, Searby C, Bugge K, Sheffield V
    Nat Med, 2012-11-18;18(12):1797-804.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Immunoprecipitation, Western Blot
  132. Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation.
    Authors: Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, Zhang Y, Zhang SZ, Ding H, Fariss RN, Becker KG, Lennartsson J, Nagai N, Cao Y, Li X
    J. Exp. Med., 2010-03-15;207(4):867-80.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  133. Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.
    Authors: Su EJ, Fredriksson L, Geyer M, Folestad E, Cale J, Andrae J, Gao Y, Pietras K, Mann K, Yepes M, Strickland DK, Betsholtz C, Eriksson U, Lawrence DA
    Nat. Med., 2008-06-22;14(7):731-7.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  134. Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis.
    Authors: Makar TK, Trisler D, Bever CT, Goolsby JE, Sura KT, Balasubramanian S, Sultana S, Patel N, Ford D, Singh IS, Gupta A, Valenzuela RM, Dhib-Jalbut S
    J. Neuroimmunol., 2008-05-08;196(1):67-81.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  135. Oligodendroglial metabotropic glutamate receptors are developmentally regulated and involved in the prevention of apoptosis.
    Authors: Luyt K, Varadi A, Durant CF, Molnar E
    J. Neurochem., 2006-07-06;99(2):641-56.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  136. Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma.
    Authors: Tejada ML, Yu L, Dong J, Jung K, Meng G, Peale FV, Frantz GD, Hall L, Liang X, Gerber HP, Ferrara N
    Clin. Cancer Res., 2006-05-01;12(9):2676-88.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P

FAQs

  1. Does Mouse PDGF R alpha Antibody, Catalog # AF1062, cross-react with rat PDGF R alpha?

    • We have not tested Catalog # AF1062 against rat samples in-house so we do not guarantee that it will detect rat PDGF R alpha. However, Uniprot indicates the homology between mouse and rat PDGF R to be 95.7%, which suggests cross-reactivity is likely. 

View all Antibody FAQs
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Mouse PDGF R alpha Antibody
By Anonymous on 05/10/2020
Application: WB Sample Tested: Adult heart Species: Mouse

3 mice hearts extractions after MI.
HSP60 was used as loading control.
There is a non specific band around 80 kDa.

Western Blot Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 05/10/2020
Application: ICC/IF Sample Tested: primary cardiac fibroblasts Species: Rat

rat primary cardiac fibroblasts, PDGFRa in red, DAPI in blue

Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 05/10/2020
Application: IHC Sample Tested: Adult heart Species: Mouse

mouse heart post MI, troponin I in green, PDGFRa in red, DAPI in blue

Immunohistochemistry Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 10/20/2019
Application: ICC/IF Sample Tested: Adult brain Species: Mouse

Dilution 1:200

Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Jun Cai on 01/16/2019
Application: ICC/IF Sample Tested: Spinal cord tissue Species: Mouse
Mouse PDGF R alpha Antibody
By Thiruloga Chandru on 07/27/2018
Application: ICC/IF Sample Tested: IPS2 induced pluripotent stem cells Species: Mouse
Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 01/25/2018
Application: WB Sample Tested: IPS2 induced pluripotent stem cells Species: Mouse
Western Blot Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 01/13/2018
Application: ICC/IF Sample Tested: Embryo Species: Mouse

differentiation assay using e12.5 mouse neural stem cells.
PDGFR (red)/ Dapi (blue)

Immunocytochemistry/Immunofluorescence Mouse PDGF R alpha Antibody AF1062
Mouse PDGF R alpha Antibody
By Anonymous on 08/10/2017
Application: IHC Sample Tested: Brain (cerebellum) tissue Species: Mouse