Phenamil
Chemical Name: 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt
Purity: ≥99%
Biological Activity
Phenamil is a TRPP3 channel inhibitor (IC50 = 0.14 μM). Also inhibits epithelial Na+ channels (Kd = 0.4 nM for a high affinity site on the epithelial Na+ channel). Derivative of amiloride (Cat. No. 0890).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Biochemical identification of two types of phenamil binding sites associated with amiloride-sensitive Na+ channels.
Barbry et al.
Biochemistry., 1989;28:3744 -
Inhibition of TRPP3 channel by amil. and analogs.
Dai et al.
Mol.Pharmacol., 2007;72:1576
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Phenamil
There are currently no reviews for this product. Be the first to review Phenamil and earn rewards!
Have you used Phenamil?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
