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Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
Potent and selective group I mGlu antagonist
Selective non-competitive mGlu1 antagonist
Highly potent, mGlu1-selective non-competitive antagonist
Competitive group I mGlu antagonist; also weak group II agonist
Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336)
Selective mGlu1a antagonist
Potent group I mGlu antagonist
Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)
Potent and selective mGlu5 antagonist
Non-selective mGlu antagonist
Selective mGlu1 antagonist
High affinity human mGlu5 antagonist
Potent and selective mGlu5 antagonist; brain penetrant
mGlu5 antagonist; orally bioavailable and brain penetrant