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3',2'-cGAMP sodium salt

Catalog #: 7718 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7718/359U
3',2'-cGAMP sodium salt | STING/TMEM173
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Description: Induces expression of STING and STING-related genes; antiviral

Chemical Name: 3',2'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt

Purity: ≥98%

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Biological Activity

3',2'-cGAMP sodium salt is a second messenger in the antiviral immune response in Drosophila melanogaster and in bacteria. 3',2'-cGAMP is selective for Drosophila stimulator of interferon genes (dSTING); induces expression of STING and STING-related genes. After injection of drosophila C virus dsRNA into Drosophila, 3',2'-cGAMP activates STING-dependent antiviral immunity in vivo, reduces viral RNA load and increases survival. In bacteria 3',2'-cGAMP activates DNA degradation of AsCap5 and LlCap5.

Technical Data

M.Wt:
718.38
Formula:
C20H22N10Na2O13P2
Solubility:
Soluble to 10 mM in water
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:
  • This product is sold in units of 359μg, equivalent to 0.5μmol.

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