Home / Additional Cytokine Receptor Products / 6877002

6877002

Catalog #: 5602 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5602/10
5602/50
6877002 | CAS No. 433249-94-6 | Additional Cytokine Receptor Products
1 Image
Description: CD40-TRAF6 interaction inhibitor

Chemical Name: 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one

Purity: ≥99%

Product Details
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

6877002 is a CD40-TRAF6 interaction inhibitor. Suppresses CD40-induced IL-1β and IL-6 expression in macrophages in vitro. Improves insulin sensitivity, reduces adipose tissue inflammation, and ameliorates hepatosteatosis in diet-induced obese mice.

Technical Data

M.Wt:
251.32
Formula:
C17H17NO
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
433249-94-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated Ins resistance.
    Chatzigeorgiou et al.
    Proc.Natl.Acad.Sci.U.S.A., 2014;111:2686

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for 6877002

There are currently no reviews for this product. Be the first to review 6877002 and earn rewards!

Have you used 6877002?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.