Angiotensin (1-7)
Purity: ≥95%
Biological Activity
Angiotensin (1-7) is an endogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats.
Lemos et al.
Br.J.Pharmacol., 2002;135:1743 -
Angiotensin-(1-7): an update.
Santos et al.
Regul.Pept., 2000;91:45 -
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas.
Santos et al.
Proc.Natl.Acad.Sci.U.S.A., 2003;100:8258
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Citation for Angiotensin (1-7)
The citations listed below are publications that use Tocris products. Selected citations for Angiotensin (1-7) include:
1 Citation: Showing 1 - 1
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FGF21 Prevents Angiotensin II-Induced Hypertension and Vascular Dysfunction by Activation of ACE2/Angiotensin-(1-7) Axis in Mice.
Authors: Pan Et al.
Cell Metab 2018;27:1323
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