Calcitonin (human)

Catalog #: 6031 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
6031/500U

1 Image

Description: Endogenous calcitonin agonist; inhibits bone resorption

Purity: ≥95%

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Biological Activity

Calcitonin (human) is an endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.

Technical Data

M.Wt:

3417.87

Formula:

C₁₅₁H₂₂₆N₄₀O₄₅S₃

Sequence:

CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP

(Modifications: Pro-32 = C-terminal amide, Disulfide bridge: 1-7)

Solubility:

Soluble to 2 mg/ml in water

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

21215-62-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Calcitonin and amylin receptor peptide interaction mechanisms.
Lee et al.
J.Biol.Chem., 2016;291:16416
Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development.
Bower et al.
Br.J.Pharmacol., 2016;173:1883
Calcitonin. A review of experimental and clinical investigations.
Foster
Postgrad.Med.J., 1968;44:411

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