Carvedilol

Catalog # Availability Size / Price Qty
2685/50
Carvedilol | CAS No. 72956-09-3 | Non-selective Adrenergic beta Receptor Antagonists
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Description: Potent and non-selective β antagonist; also potent α1 antagonist
Alternative Names: BM 14190

Chemical Name: 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol

Purity: ≥98%

Product Details
Citations (3)
Reviews

Biological Activity

Carvedilol is a potent β-adrenoceptor and α1-adrenoceptor antagonist (Ki values are 0.81, 0.96 and 2.2 nM for β1-, β2- and α1-adrenoceptors respectively) that displays antihypertensive and peripheral vasodilatory activity. Blocks cardiac inward-rectifier K+ (KIR) channels, voltage-dependent Ca2+ channels and exhibits antioxidant properties at higher concentrations.

Technical Data

M.Wt:
406.47
Formula:
C24H26N2O4
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
72956-09-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Carvedilol

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3 Citations: Showing 1 - 3

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