Cetrorelix acetate New
Purity: ≥95%
Biological Activity
Cetrorelix acetate is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist (KD = 0.202 nM, IC50 = 1.21 nM). Suppresses production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, which inhibits ovulation. Exhibits antiproliferative effects and displays efficacy against hormone-sensitive cancers in vivo. Also exhibits anxiolytic and antidepressant activity in vivo.Technical Data
(Modifications: X-1 = D-2-Nal and N-terminal Ac, Phe-2 = 4-Cl-D-Phe, X-3 = 3-(3-Pyridyl)-D-Ala), X-6 = D-Cit, Ala-10 = D-Ala and C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
Characterization of gonadotropin-releasing hormone analogs based on a sensitive cellular luciferase reporter gene assay.
Beckers et al.
Anal.Biochem., 1997;251:17 -
Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer.
Grundker and Emons
Reprod.Biol.Endocrinol., 2003;1:65 -
Effects of the LHRH antagonist cetro. on the brain function in mice.
Telegdy et al.
Neuropeptides, 2009;43:229
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsReviews for Cetrorelix acetate
There are currently no reviews for this product. Be the first to review Cetrorelix acetate and earn rewards!
Have you used Cetrorelix acetate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
