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Chlormezanone

Catalog #: 0456 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
0456/50
Chlormezanone | CAS No. 80-77-3 | GABA-A Receptor Benzodiazepines
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Description: Positive allosteric modulator of benzodiazepine site

Chemical Name: 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one-1,1-dioxide

Purity: ≥99%

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Biological Activity

Chlormezanone is a anxiolytic and skeletal muscle relaxant that acts at the benzodiazepine site of GABAA receptors.

Technical Data

M.Wt:
273.73
Formula:
C11H12ClNO3S
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
80-77-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Use of conditioned taste aversion as a conflict model: effects of anxiolytic drugs.
    Ervin and Cooper
    J.Pharmacol.Exp.Ther., 1988;245:137
  2. Comparative study in mice of tetrazepam and other centrally active skeletal muscle relaxants.
    Simiand et al.
    Arch.Int.Pharmacodyn.Ther., 1989;297:272

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