Cyno Monkey NKp44/NCR2 (NP_001306466.1) VersaClone cDNA

Catalog #: RDC3201 Datasheet / COA / SDS

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RDC3201

Cyno Monkey NKp44/NCR2 (NP_001306466.1) VersaClone cDNA

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Cyno Monkey NKp44/NCR2 (NP_001306466.1) VersaClone cDNA Summary

Specifications

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Cynomolgus Monkey

Product Datasheets

Product Datasheet

COA

SDS

Background: NKp44/NCR2

NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.

Long Name

NK Cell Activating Receptor

Entrez Gene IDs

9436 (Human); 102129442 (Cynomolgus Monkey)

Alternate Names

CD336 antigen; CD336; LY95; LY95lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); lymphocyte antigen 95 (activating NK-receptor; NK-p44); Lymphocyte antigen 95 homolog; natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; NCR2; NK cell activating receptor (NKp44); NK cell-activating receptor; NKp44; NK-p44dJ149M18.1