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Diltiazem hydrochloride

Catalog #: 0685
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
0685/1G
Diltiazem hydrochloride | CAS No. 33286-22-5 | Cav1.x Channel Blockers
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Description: CaV1.x blocker

Chemical Name: (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride

Purity: ≥98%

Product Details
Citations (5)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Diltiazem hydrochloride is an antihypertensive and cardioprotective agent; an inhibitor of L-type Ca2+ channels.

Technical Data

M.Wt:
450.98
Formula:
C22H26N2O4S.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
33286-22-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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⚠ WARNING: This product can expose you to chemicals including Diltiazem hydrochloride, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citations for Diltiazem hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Diltiazem hydrochloride include:

5 Citations: Showing 1 - 5

  1. DTZ improves contractile properties of skeletal muscle in dysferlin-deficient BLAJ mice, but does not reduce contraction-induced muscle damage.
    Authors: Begam Et al.
    Physiol Rep  2018;6:e13727
  2. Resveratrol enhances the inotropic effect but inhibits the proarrhythmic effect of sympathomimetic agents in rat myocardium.
    Authors: Hernández-Cascales
    PeerJ  2017;5:e3113
  3. Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes.
    Authors: Lobeck Et al.
    Virology  2016;499:185
  4. Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
    Authors: Cramer Et al.
    PLoS One  2015;35:5664
  5. Dissecting out the complex Ca2+-mediated phenylephrine-induced contractions of mouse aortic segments.
    Authors: Fransen Et al.
    Brain Behav  2015;10:e0121634

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