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FMK 9a

Catalog #: 7496 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7496/2
Description: Potent ATG4B/autophagin-1 inhibitor; also inhibits calpain and cathepsin B

Chemical Name: N-[(1S)-2-[(3-Fluoro-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-1-naphthalenecarboxamide

Purity: ≥90%

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Biological Activity

FMK 9a is a potent ATG4B/autophagin-1 inhibitor (IC50 values are 73 nM and 80 nM in cell-based LRA and TR-FRET assays, respectively). Also inhibits calpain and cathepsin B (IC50 vales 96 nM and 200 nM, respectively).

Technical Data

M.Wt:
392.43
Formula:
C23H21FN2O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥90%
Storage:
Store at -20°C
CAS No:
1955550-51-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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