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FURA-2AM

Catalog #: 2220
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2220/1
FURA-2AM | CAS No. 108964-32-5 | Ion Indicators
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Description: Fluorescent Ca2+ indicator

Chemical Name: 2-[6-[bis[2-[(Acetyloxy)methoxy]-2-oxoethyl]amino]-5-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-2-benzofuranyl]-5-oxazolecarboxylic acid (acetyloxy)methyl ester

Purity: ≥95%

Product Details
Citations (3)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

FURA-2AM is a fluorescent ratiometric Ca2+ indicator (Kd Ca2+ = 145 nM). FURA-2AM is selective for Ca2+ over other divalent cations Mg2+, Zn2+, Fe2+ and Mn2+. FURA-2AM binds to free intracellular calcium and is used to determine [Ca2+]i concentration.

This product is typically prepared in DMSO. F 127 (Cat. No. 6253) for the solubilization of FURA-2AM is also available.

Technical Data

M.Wt:
1001.85
Formula:
C44H47N3O24
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
108964-32-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for FURA-2AM

The citations listed below are publications that use Tocris products. Selected citations for FURA-2AM include:

3 Citations: Showing 1 - 3

  1. Niclosamide repurposed for the treatment of inflammatory airway disease.
    Authors: Cabrita Et al.
    JCI Insight  2019;4
  2. KA attenuates the Na+-dependent Ca2+ overload in rabbit ventricular myocytes in vitro by inhibiting late Na+ and L-type Ca2+ currents.
    Authors: Luo Et al.
    Mol Neurodegener  2015;36:1327
  3. Characterisation of AmphiAmR11, an amphioxus (Branchiostoma floridae) D2-DA-like G protein-coupled receptor.
    Authors: Bayliss and Evans
    PLoS One  2013;8:e80833

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