Human BMP-2 Antibody Summary
Gln283-Arg396
Accession # P12643
Applications
Human BMP-2 Sandwich Immunoassay
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: BMP-2
BMP-2 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor beta (TGF-beta ) superfamily, BMPs were originally identified as protein regulators of cartilage and bone formation. However, they have since been shown to be involved in embryogenesis and morphogenesis of various tissues and organs.
Product Datasheets
Citations for Human BMP-2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
11
Citations: Showing 1 - 10
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Osteogenic differentiation of human mesenchymal stromal cells and fibroblasts differs depending on tissue origin and replicative senescence
Authors: V Grotheer, N Skrynecki, L Oezel, J Grassmann, J Windolf, CV Suschek
Scientific Reports, 2021-06-07;11(1):11968.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Selective endocytosis of recombinant human BMPs through cell surface heparan sulfate proteoglycans in CHO cells: BMP-2 and BMP-7
Authors: MG Kim, CL Kim, YS Kim, JW Jang, GM Lee
Scientific Reports, 2021-02-09;11(1):3378.
Species: Hamster
Sample Types: Cell Lysates
Applications: Western Blot -
TNF? drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling
Authors: LA Hurst, BJ Dunmore, L Long, A Crosby, R Al-Lamki, J Deighton, M Southwood, X Yang, MZ Nikolic, B Herrera, GJ Inman, JR Bradley, AA Rana, PD Upton, NW Morrell
Nat Commun, 2017-01-13;8(0):14079.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Osteogenic Surface Modification Based on Functionalized Poly-P-Xylylene Coating.
Authors: Chang C, Yeh S, Lee B, Chen C, Su C, Lin Y, Liu C, Chen H
PLoS ONE, 2015-09-17;10(9):e0137017.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay -
Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade.
Authors: Du Y, Xiao Q, Yip HK
Invest. Ophthalmol. Vis. Sci., 2010-02-03;51(7):3764-73.
Species: Mouse
Sample Types: Tissue Homogenates, Whole Tissue
Applications: IHC, Western Blot -
Periodontal regeneration using ex vivo autologous stem cells engineered to express the BMP-2 gene: an alternative to alveolaplasty.
Authors: Chen YL, Chen PK, Jeng LB, Huang CS, Yang LC, Chung HY, Chang SC
Gene Ther., 2008-08-14;15(22):1469-77.
Species: Rabbit
Sample Types: Cell Lysates
Applications: Western Blot -
Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
Authors: Kane R, Godson C, O'Brien C
Mol. Vis., 2008-06-20;14(0):1138-48.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Targeting of bone morphogenetic protein growth factor complexes to fibrillin.
Authors: Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bachinger HP, Sakai LY
J. Biol. Chem., 2008-03-13;283(20):13874-88.
Species: Human
Sample Types: Recombinant Protein
Applications: Western Blot -
Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin.
Authors: Kuns-Hashimoto R, Kuninger D, Nili M, Rotwein P
Am. J. Physiol., Cell Physiol., 2008-02-20;294(4):C994-C1003.
Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
Sample Types: Cell Culture Supernates, Whole Cells
Applications: ICC, Immunoprecipitation -
Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism.
Authors: Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller ET
Cancer Res., 2005-09-15;65(18):8274-85.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer.
Authors: Kayed H, Kleeff J, Keleg S, Guo J, Ketterer K, Berberat P, Giese N, Esposito I, Giese T, Buchler M, Friess H
Int J Cancer, 2004-07-10;110(5):668-76.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot
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