Human CCK-AR Alexa Fluor® 594-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB2680T-100UG
R&D Systems Antibodies
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Human CCK-AR Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human CCK‑A R. Stains human CCK-A R transfectants but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2a Clone # 377251
Immunogen
NS0 mouse myeloma cell line transfected with human CCK‑A R
Met1-Gln428
Accession # P32238
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Human CCK‑A R transfected cells

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CCK-AR

Cholecystokinin A Receptor (CCK-A R) is one of two 7TM receptors for cholecystokinin peptide hormones. This GPCR is involved in gallbladder contraction, insulin secretion, and central nervous system function. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction. Human CCK-A R shares 89% aa sequence identity with mouse and rat CCK-A R.

Long Name
Cholecystokinin Receptor, Type A
Entrez Gene IDs
886 (Human); 12425 (Mouse)
Alternate Names
CCK1R; CCK1-R; CCK-A R; CCK-A receptor; CCK-A; CCKAR; CCK-AR; CCKRA; cholecystokinin A receptor; cholecystokinin receptor type A; cholecystokinin type-A receptor; Cholecystokinin-1 receptor

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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