Human CD11c PerCP-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB1777C-100
FAB1777C-025
Detection of CD11c in Human Blood Monocytes by Flow Cytometry.
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Human CD11c PerCP-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human CD11c in flow cytometry.
Source
Monoclonal Mouse IgG1 Clone # ICRF 3.9
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Rheumatoid synovial fluid cells and human monocyte-derived fibronectin
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
PerCP (Peridinin-chlorophyll Protein Complex) (Excitation= 482 and 564 nm, Emission= 675 nm)
Purity
Protein A or G purified from hybridoma culture supernatant

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CD11c antibody in Human Blood Monocytes antibody by Flow Cytometry. View Larger

Detection of CD11c in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CD11c PerCP-conjugated Monoclonal Antibody (Catalog # FAB1777C, filled histogram) or isotype control antibody (Catalog # IC002C, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD11c

Integrin alpha X, also known as CD11c, heterodimerizes with Integrin beta 2, also known as CD18. The CD11c/CD18 complex binds fibrinogen and has been reported to be a receptor for iC3b (1‑3) .

References
  1. Hogg, N. et al. (1986) Eur. J. Immunol. 16(3):240.
  2. Knapp, W.B. et al. eds. (1989) Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.
  3. Stacker, S.A. and T.A. Springer, J. Immunol. (1991) 146(2):648.
Entrez Gene IDs
3687 (Human); 16411 (Mouse); 64350 (Rat)
Alternate Names
95 alpha chain; 95; 95, alpha subunit; CD11 antigen-like family member C; CD11c antigen; CD11c; CD11Cleu M5, alpha subunit; Integrin alpha X; integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); ITGAX; Leu M5; Leukocyte adhesion glycoprotein p150; Leukocyte adhesion receptor p150; leukocyte surface antigen p150; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain; p150,95 alpha; SLEB6

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