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Human CD14 ELISA Kit - Quantikine

Catalog #: DC140
130 Citations 9 Reviews Datasheet / COA / SDS
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Human CD14 ELISA Standard Curve
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Summary Precision Recovery Linearity Data Examples Product Datasheets Preparation and Storage Background Related Research Areas

Human CD14 Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Citrate Plasma (10 uL)
Sensitivity
125 pg/mL
Assay Range
250.0 - 16,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
Specificity
Natural and recombinant human sCD14
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine Human soluble CD14 Immunoassay is a 4.5 hour solid phase ELISA designed to measure human soluble CD14 in cell culture supernates, serum, and plasma. It contains recombinant human CD14 expressed from CHO cells and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained measuring natural human sCD14 showed dose-response curves that were parallel to the standard curves obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for natural human sCD14.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean (pg/mL) 1111 2158 4187 1159 2298 4346
Standard Deviation 71 104 216 86 153 209
CV% 6.4 4.8 5.2 7.4 6.7 4.8

Recovery

The recovery of sCD14 spiked to three different levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=5) 91 85-105
Citrate Plasma (n=5) 102 88-110
EDTA Plasma (n=5) 98 90-107
Heparin Plasma (n=5) 96 91-104
Serum (n=5) 98 84-107

Linearity

To assess the linearity of the assay, five samples containing or spiked with high concentrations of sCD14 were diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human CD14 ELISA Linearity

Scientific Data

N/A Human CD14 ELISA Standard Curve View Larger

Human CD14 ELISA Standard Curve

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CD14

CD14 is a glycoprotein that mediates the interaction of lipopolysaccharide (LPS, endotoxin)with cells, thereby signaling the presence of gram-negative bacteria (1-3). CD14 is eithersoluble (CD14) (4, 5) or membrane-bound (mCD14) by a glycosylphosphatidylinositol (GPI)anchor (6, 7). mCD14 is a 55 kDa glycoprotein (1), while CD14 varies from about 43 to 53 kDa,depending on the degree of glycosylation and whether it was synthesized without the anchoror was shed by phospholipase cleavage of the anchor or by proteolysis (12-14). There is noevidence for different mRNAs for m- and CD14. There is no apparent sequence homology withother proteins. The sequence of human CD14 is 63-73% identical to that of mouse, rat, or rabbitCD14 (15).

mCD14 is expressed primarily on myeloid cells, such as monocytes, macrophages andneutrophils (1-3), the cells most sensitive to LPS, and to a lesser extent on other cells, such as Bcells (8) and a circulating dendritic cell progenitor (9). CD14 appears to mediate LPS stimulationof cells that do not express mCD14 (10, 11), such as endothelial, epithelial and smooth-musclecells. CD14 is found in both serum and urine (5).
The binding of LPS to CD14 requires an acute phase protein, LPS-binding protein (LBP) (16).The relationship of mCD14, CD14, LPS and LBP is complicated. At low concentrations of LPS,LBP is essential for the binding of LPS to CD14, but at high concentrations, LBP may actuallyinhibit binding of LPS to CD14. In addition, CD14 may compete with mCD14 for LPS (17) andmay serve to help clear LPS (18). These four factors thus appear to participate in a complexfeedback mechanism of immune regulation involving both up-regulation and down-regulationof the inflammatory process triggered by LPS. It is loss of control of this mechanism thatappears to lead to septic shock. LPS-bound CD14 signals production of inflammatory cytokinesand other inflammatory proteins, but the mechanism of signal transduction is unclear. Sincea GPI anchor is not transmembrane, there presumably is another transmembrane protein oncells through which LPS-bound CD14 transmits a signal (19).
In addition to its well known role in gram-negative infections, CD14 likely serves otherfunctions as well. It recognizes soluble peptidylglycan from gram-positive cell walls (20), and ithas been reported to bind apoptotic cells and induce their phagocytosis (21).

Entrez Gene IDs:
929 (Human); 12475 (Mouse); 60350 (Rat); 100037938 (Porcine)
Alternate Names:
CD14 antigen; CD14 molecule; CD14; monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
    3. 100 µL Assay Diluent
  3.   Add 100 µL of Assay Diluent to each well.
    4. 100 µL Standard, Control, or Sample
  4.   Add 100 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 3 hours.
  5.   Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.
    6. 200 µL Conjugate
  6.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 1 hour.
  7.   Aspirate and wash 4 times.
    8. 200 µL Substrate Solution
  8.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
    9. 50 µL Stop Solution
  9.   Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Human CD14 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

130 Citations: Showing 1 - 10
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  1. HIV-associated gut microbial alterations are dependent on host and geographic context
    Authors: Rocafort, M;Gootenberg, DB;Luévano, JM;Paer, JM;Hayward, MR;Bramante, JT;Ghebremichael, MS;Xu, J;Rogers, ZH;Munoz, AR;Okello, S;Kim, JH;Sentongo, R;Wagubi, R;Lankowski, A;Maruapula, S;Zhao, G;Handley, SA;Mosepele, M;Siedner, MJ;Kwon, DS;
    Nature communications
    Species: Human hepegivirus
    Sample Types: Plasma
  2. Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys
    Authors: Q Le Hingrat, P Sette, C Xu, AR Rahmberg, L Tarnus, H Annapuredd, A Kleinman, E Brocca-Cof, R Sivanandha, S Sivanandha, T He, DJ Capreri, D Ma, JD Estes, JM Brenchley, C Apetrei, I Pandrea
    Nature Communications, 2023-02-22;14(1):979.
    Species: Primate - Chlorocebus sabaeus (Green Monkey)
    Sample Types: Plasma
  3. Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus
    Authors: LP Kincer, SB Joseph, MM Gilleece, BM Hauser, S Sizemore, S Zhou, C Di Germani, H Zetterberg, D Fuchs, SG Deeks, S Spudich, M Gisslen, RW Price, R Swanstrom
    Nature Microbiology, 2023-01-30;8(2):260-271.
    Species: Human
    Sample Types: CSF
  4. Cerebrovascular pulsatility index is higher in chronic kidney disease
    Authors: ES Oh, KA Freeberg, CN Steele, W Wang, H Farmer-Bai, ME Coppock, DR Seals, M Chonchol, MJ Rossman, DH Craighead, KL Nowak
    Physiological Reports, 2023-01-01;11(1):e15561.
    Species: Human
    Sample Types: Serum
  5. Longitudinal multi-omics analyses of the gut-liver axis reveals metabolic dysregulation in hepatitis C infection and cirrhosis
    Authors: RO Ali, GM Quinn, R Umarova, JA Haddad, GY Zhang, EC Townsend, L Scheuing, KL Hill, M Gewirtz, S Rampertaap, SD Rosenzweig, AT Remaley, JM Han, V Periwal, H Cai, PJ Walter, C Koh, EB Levy, DE Kleiner, O Etzion, T Heller
    Nature Microbiology, 2022-12-15;0(0):.
    Species: Human
    Sample Types: Serum
  6. Long-Term Associations between Human Cytomegalovirus Antibody Levels with All-Cause Mortality and Cardiovascular Outcomes in an Australian Community-Based Cohort
    Authors: S Lee, N van den Be, A Castley, M Divitini, M Knuiman, P Price, D Nolan, F Sanfilippo, G Dwivedi
    Viruses, 2022-11-29;14(12):.
    Species: Human
    Sample Types: Serum
  7. The biological activity of serum bacterial lipopolysaccharides associates with disease activity and likelihood of achieving remission in patients with rheumatoid arthritis
    Authors: J Parantaine, G Barreto, R Koivuniemi, H Kautiainen, D Nordström, E Moilanen, M Hämäläinen, M Leirisalo-, K Nurmi, KK Eklund
    Arthritis Research & Therapy, 2022-11-21;24(1):256.
    Species: Human
    Sample Types: Serum
  8. Longitudinal Assessment of Multiple Immunological and Inflammatory Parameters during Successful DAA Therapy in HCV Monoinfected and HIV/HCV Coinfected Subjects
    Authors: P Zuccalà, T Latronico, R Marocco, S Savinelli, S Vita, F Mengoni, T Tieghi, C Borgo, B Kertusha, A Carraro, G D'Ettorre, V Vullo, CM Mastroiann, GM Liuzzi, M Lichtner
    International Journal of Molecular Sciences, 2022-10-08;23(19):.
    Species: Human
    Sample Types: Plasma
  9. Circulating biomarker correlates of left atrial size and myocardial extracellular volume fraction among persons living with and without HIV
    Authors: TE Peterson, C Landon, SA Haberlen, F Bhondoekha, MW Plankey, FJ Palella, DA Piggott, JB Margolick, TT Brown, WS Post, KC Wu
    BMC cardiovascular disorders, 2022-09-03;22(1):393.
    Species: Human
    Sample Types: Serum
  10. The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence
    Authors: Z Strongin, TN Hoang, GK Tharp, AR Rahmberg, JL Harper, K Nguyen, L Franchitti, B Cervasi, M Lee, Z Zhang, EA Boritz, G Silvestri, VC Marconi, SE Bosinger, JM Brenchley, DA Kulpa, M Paiardini
    PloS Pathogens, 2022-07-22;18(7):e1010723.
    Species: Human
    Sample Types: Plasma
  11. Vascular Calcification and the Gut and Blood Microbiome in Chronic Kidney Disease Patients on Peritoneal Dialysis: A Pilot Study
    Authors: A Merino-Rib, R Araujo, L Pereira, J Campos, L Barreiros, MA Segundo, N Silva, CFFA Costa, J Quelhas-Sa, F Trindade, I Falcão-Pir, I Alencastre, IB Dumitrescu, B Sampaio-Ma
    Biomolecules, 2022-06-21;12(7):.
    Species: Human
    Sample Types: Plasma
  12. Impact of illicit opioid use on markers of monocyte activation and systemic inflammation in people living with HIV
    Authors: A Kholodnaia, K So-Armah, D Cheng, N Gnatienko, G Patts, JH Samet, M Freiberg, D Lioznov
    PLoS ONE, 2022-05-05;17(5):e0265504.
    Species: Human
    Sample Types: Serum
  13. Liver alterations are not improved by inulin supplementation in alcohol use disorder patients during alcohol withdrawal: A pilot randomized, double-blind, placebo-controlled study
    Authors: C Amadieu, L Maccioni, S Leclercq, AM Neyrinck, NM Delzenne, P de Timary, P Stärkel
    EBioMedicine, 2022-04-28;80(0):104033.
    Species: Human
    Sample Types: Plasma
  14. Inflammatory Markers after Switching to a Dual Drug Regimen in HIV-Infected Subjects: A Two-Year Follow-Up
    Authors: M Vassallo, J Durant, R Fabre, L Lotte, A Sindt, A Puchois, A De Monte, R Cezar, P Corbeau, C Pradier
    Viruses, 2022-04-28;14(5):.
    Species: Human
    Sample Types: Plasma
  15. Maternal breast milk microbiota and immune markers in relation to subsequent development of celiac disease in offspring
    Authors: J Štšepetova, K Simre, A Tagoma, O Uibo, A Peet, H Siljander, V Tillmann, M Knip, R Mändar, R Uibo
    Scientific Reports, 2022-04-22;12(1):6607.
    Species: Human
    Sample Types: Breast Milk
  16. Immune Activation in Primary Human Immunodeficiency Virus: Influence of Duration of Infection, Treatment, and Substance Use
    Authors: T Gilada, SR Schnittman, E White, J Mercader, Y Wang, S Dasgupta, R Valdez, D Pinto-Sant, S Pasalar, J Sanchez, P Gonzales, JR Lama, R Bender Ign, A Duerr
    Open forum infectious diseases, 2022-03-24;9(6):ofac155.
    Species: Human
    Sample Types: Plasma
  17. Blood-brain barrier and gut barrier dysfunction in chronic kidney disease with a focus on circulating biomarkers and tight junction proteins
    Authors: L Hernandez, LJ Ward, S Arefin, T Ebert, A Laucyte-Ci, GOING-FWD, O Heimbürger, P Barany, L Wennberg, P Stenvinkel, K Kublickien
    Scientific Reports, 2022-03-15;12(1):4414.
    Species: Human
    Sample Types: Serum
  18. Targeting the Gut Microbiota of Vertically HIV-Infected Children to Decrease Inflammation and Immunoactivation: A Pilot Clinical Trial
    Authors: T Sainz, L Diaz, D Rojo, MI Clemente, C Barbas, MJ Gosalbes, N Jimenez-He, L Escosa, S Guillen, JT Ramos, MÁ Muñoz-Fern, ML Navarro, MJ Mellado, S Serrano-Vi
    Nutrients, 2022-02-26;14(5):.
    Species: Human
    Sample Types: Plasma
  19. Maternal inflammatory and omega-3 fatty acid pathways mediate the association between socioeconomic disadvantage and childhood cognition
    Authors: W Marx, S Thomson, M O'Hely, C Symeonides, F Collier, MLK Tang, A Loughman, D Burgner, R Saffery, C Pham, T Mansell, PD Sly, P Vuillermin, S Ranganatha, AL Ponsonby, Barwon Inf
    Brain, Behavior, and Immunity, 2021-12-08;100(0):211-218.
    Species: Human
    Sample Types: Serum
  20. Translocating lipopolysaccharide correlates with the severity of enterovirus A71-induced HFMD by promoting pro-inflammation and viral IRES activity
    Authors: Y Wang, K Dan, X Xue, X Yang, X Feng, Q Yang, J Yang, B Chen
    Gut pathogens, 2021-11-22;13(1):69.
    Species: Human
    Sample Types: Serum
  21. Biomarkers of disease severity in patients with visceral leishmaniasis co-infected with HIV
    Authors: GR Ferreira, JR Santos-Oli, ML Silva-Frei, M Honda, DL Costa, AM Da-Cruz, CHN Costa
    Cytokine, 2021-10-27;149(0):155747.
    Species: Human
    Sample Types: Serum
  22. Dysbiosis of Gut Microbiota Promotes Hepatocellular Carcinoma Progression by Regulating the Immune Response
    Authors: N Zhang, Y Gou, S Liang, N Chen, Y Liu, Q He, J Zhang
    Journal of Immunology Research, 2021-10-20;2021(0):4973589.
    Species: Human
    Sample Types: Plasma
  23. A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis
    Authors: LC Alexander, G McHorse, JL Huebner, AC Bay-Jensen, MA Karsdal, VB Kraus
    Arthritis Research & Therapy, 2021-08-31;23(1):226.
    Species: Human
    Sample Types: Plasma
  24. Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms
    Authors: MJ Peluso, AN Deitchman, L Torres, NS Iyer, SE Munter, CC Nixon, J Donatelli, C Thanh, S Takahashi, J Hakim, K Turcios, O Janson, R Hoh, V Tai, Y Hernandez, EA Fehrman, MA Spinelli, M Gandhi, L Trinh, T Wrin, CJ Petropoulo, FT Aweeka, I Rodriguez-, JD Kelly, JN Martin, SG Deeks, B Greenhouse, RL Rutishause, TJ Henrich
    Cell Reports, 2021-08-06;36(6):109518.
    Species: Human
    Sample Types: Serum
  25. Soluble cluster of differentiation 14 levels elevated in bile from gallbladder cancer cases from Shanghai, China
    Authors: VL Brun, AF Corbel, AW Hsing, TJ Kemp, AL Van Dyke, A Hildesheim, B Zhu, YT Gao, LA Pinto, J Koshiol
    Scientific Reports, 2021-06-28;11(1):13405.
    Species: Human
    Sample Types: Bile
  26. Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques
    Authors: MP Wood, CI Jones, A Lippy, BG Oliver, B Walund, KA Fancher, BS Fisher, PJ Wright, JT Fuller, P Murapa, J Habib, M Mavigner, A Chahroudi, DN Sather, DH Fuller, DL Sodora
    PloS Pathogens, 2021-05-07;17(5):e1009575.
    Species: Human
    Sample Types: Plasma
  27. Inflammatory Markers During Early Treatment of Seroconverters in a Randomized Placebo-Controlled Trial of PrEP (ANRS-IPERGAY)
    Authors: S Chawki, I Charreau, A Gabassi, D Carette, E Cua, L Cotte, G Pialoux, C Pintado, L Meyer, ML Chaix, C Delaugerre, JM Molina
    Open forum infectious diseases, 2021-03-20;8(3):ofab085.
    Species: Human
    Sample Types: Plasma
  28. B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy
    Authors: S Sendic, L Mansouri, S Lundberg, A Nopp, SH Jacobson, J Lundahl
    PLoS ONE, 2021-03-19;16(3):e0248056.
    Species: Human
    Sample Types: Plasma
  29. Insomnia symptoms and biomarkers of monocyte activation, systemic inflammation, and coagulation in HIV: Veterans Aging Cohort Study
    Authors: BM Polanka, S Kundu, KA So-Armah, MS Freiberg, SK Gupta, TCB Zapolski, AT Hirsh, RJ Bedimo, MJ Budoff, AA Butt, CH Chang, SS Gottlieb, VC Marconi, JA Womack, JC Stewart
    PLoS ONE, 2021-02-09;16(2):e0246073.
    Species: Human
    Sample Types: Serum
  30. Identifying a biological signature of prenatal maternal stress
    Authors: JM Keane, AS Khashan, FP McCarthy, LC Kenny, JM Collins, SM O'Donovan, JR Brown, JF Cryan, TG Dinan, G Clarke, SM O'Mahony
    JCI Insight, 2021-01-25;0(0):.
    Species: Human
    Sample Types: Serum
  31. Identification of distinct immune activation profiles in adult humans
    Authors: R Cezar, A Winter, D Desigaud, M Pastore, L Kundura, AM Dupuy, C Cognot, T Vincent, C Reynes, C Dunyach-Re, JP Lavigne, R Sabatier, P Le Merre, E Maggia, P Corbeau
    Scientific Reports, 2020-11-30;10(1):20824.
    Species: Human
    Sample Types: Plasma
  32. The Differences between Gluten Sensitivity, Intestinal Biomarkers and Immune Biomarkers in Patients with First-Episode and Chronic Schizophrenia
    Authors: M Dzikowski, D Juchnowicz, I Dzikowska, J Rog, M Próchnicki, M Kozio?, H Karakula-J
    J Clin Med, 2020-11-18;9(11):.
    Species: Human
    Sample Types: Serum
  33. Endotoxemia coupled with heightened inflammation predicts future depressive symptoms
    Authors: AA Madison, R Andridge, AC Padin, S Wilson, MT Bailey, CM Alfano, SP Povoski, AM Lipari, DM Agnese, WE Carson, WB Malarkey, JK Kiecolt-Gl
    Psychoneuroendocrinology, 2020-10-08;122(0):104864.
    Species: Human
    Sample Types: Serum
  34. Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis
    Authors: DR Beers, W Zhao, DW Neal, JR Thonhoff, AD Thome, A Faridar, S Wen, J Wang, SH Appel
    Scientific Reports, 2020-09-17;10(1):15295.
    Species: Human
    Sample Types: Serum
  35. Interferon-alpha alters host glycosylation machinery during treated HIV infection
    Authors: LB Giron, F Colomb, E Papasavvas, L Azzoni, X Yin, M Fair, A Anzurez, M Damra, K Mounzer, JR Kostman, P Tebas, U O'Doherty, H Tateno, Q Liu, MR Betts, LJ Montaner, M Abdel-Mohs
    EBioMedicine, 2020-08-19;59(0):102945.
    Species: Human
    Sample Types: Plasma
  36. Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma
    Authors: SP Polster, A Sharma, C Tanes, AT Tang, P Mericko, Y Cao, J Carrión-Pe, R Girard, J Koskimäki, D Zhang, A Stadnik, SG Romanos, SB Lyne, R Shenkar, K Yan, C Lee, A Akers, L Morrison, M Robinson, A Zafar, K Bittinger, H Kim, JA Gilbert, ML Kahn, L Shen, IA Awad
    Nat Commun, 2020-05-27;11(1):2659.
    Species: Human
    Sample Types: Plasma
  37. Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
    Authors: S Vieira-Sil, G Falony, E Belda, T Nielsen, J Aron-Wisne, R Chakaroun, SK Forslund, K Assmann, M Valles-Col, TTD Nguyen, S Proost, E Prifti, V Tremaroli, N Pons, E Le Chateli, F Andreelli, JP Bastard, LP Coelho, N Galleron, TH Hansen, JS Hulot, C Lewinter, HK Pedersen, B Quinquis, C Rouault, H Roume, JE Salem, NB Søndertoft, S Touch, ME Dumas, SD Ehrlich, P Galan, JP Gøtze, T Hansen, JJ Holst, L Køber, I Letunic, J Nielsen, JM Oppert, M Stumvoll, H Vestergaar, JD Zucker, P Bork, O Pedersen, F Bäckhed, K Clément, J Raes
    Nature, 2020-05-06;581(7808):310-315.
    Species: Human
    Sample Types: Serum
  38. Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals
    Authors: M Nayrac, M Requena, C Loiseau, M Cazabat, B Suc, N Carrere, K Barange, L Alric, G Martin-Blo, J Izopet, P Delobel
    Mucosal Immunol, 2020-04-28;0(0):.
    Species: Human
    Sample Types: Plasma
  39. Biomarkers of Cellular Stress Do Not Associate with sCD14 in Progressive HIV and SIV Infections in Vivo
    Authors: CL Vinton, CE Starke, AM Ortiz, SH Lai, JK Flynn, O Sortino, K Knox, I Sereti, JM Brenchley
    Pathog Immun, 2020-04-24;5(1):68-88.
    Species: Human, Rhesus Macaca (Macaque)
    Sample Types: Plasma
  40. Sialylation and fucosylation modulate inflammasome-activating eIF2 Signaling and microbial translocation during HIV infection
    Authors: LB Giron, CE Tanes, MH Schleimann, PA Engen, LM Mattei, A Anzurez, M Damra, H Zhang, K Bittinger, F Bushman, A Kossenkov, PW Denton, H Tateno, A Keshavarzi, AL Landay, M Abdel-Mohs
    Mucosal Immunol, 2020-03-09;0(0):.
    Species: Human
    Sample Types: Plasma
  41. African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity
    Authors: KD Raehtz, F Barrenäs, C Xu, K Busman-Sah, A Valentine, L Law, D Ma, BB Policicchi, V Wijewardan, E Brocca-Cof, A Trichel, M Gale, BF Keele, JD Estes, C Apetrei, I Pandrea
    PLoS Pathog., 2020-03-02;16(3):e1008333.
    Species: Primate
    Sample Types: Plasma
  42. New signatures of poor CD4 cell recovery after suppressive antiretroviral therapy in HIV-1-infected individuals: involvement of miR-192, IL-6, sCD14 and miR-144
    Authors: F Hernández-, MJ Ruiz-de-Le, I Rosado-Sán, E Vázquez, M Leal, S Moreno, F Vidal, J Blanco, YM Pacheco, A Vallejo
    Sci Rep, 2020-02-19;10(1):2937.
    Species: Human
    Sample Types: Plasma
  43. HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells
    Authors: Y Wang, L Lifshitz, K Gellatly, CL Vinton, K Busman-Sah, S McCauley, P Vangala, K Kim, A Derr, S Jaiswal, A Kucukural, P McDonel, PW Hunt, T Greenough, J Houghton, M Somsouk, JD Estes, JM Brenchley, M Garber, SG Deeks, J Luban
    Nat. Immunol., 2020-02-17;21(3):274-286.
  44. Plasma FABP4 is associated with liver disease recovery during treatment-induced clearance of chronic HCV infection
    Authors: JB Gorin, DFG Malone, B Strunz, T Carlsson, S Aleman, NK Björkström, K Falconer, JK Sandberg
    Sci Rep, 2020-02-07;10(1):2081.
    Species: Human
    Sample Types: Plasma
  45. Factor Xa Inhibition Reduces Coagulation Activity but Not Inflammation Among People With HIV: A Randomized Clinical Trial
    Authors: JV Baker, J Wolfson, T Peterson, M Mooberry, M Gissel, H Mystakelis, MW Henderson, K Garcia-Mye, FS Rhame, TW Schacker, KE Brummel-Zi, I Sereti, NS Key, RP Tracy
    Open Forum Infect Dis, 2020-02-01;7(2):ofaa026.
    Species: Human
    Sample Types: Serum
  46. Impact of Raltegravir or Efavirenz on Cell-Associated Human Immunodeficiency Virus-1 (HIV-1) Deoxyribonucleic Acid and Systemic Inflammation in HIV-1/Tuberculosis Coinfected Adults Initiating Antiretroviral Therapy
    Authors: HM Delagrever, C Bauduin, N De Castro, B Grinsztejn, M Chevrier, F Jouenne, S Mourah, I Kalidi, JH Pilotto, C Brites, N Tregnago B, A Amara, L Wittkop, JM Molina, C Delaugerre
    Open Forum Infect Dis, 2020-01-11;7(2):ofz549.
    Species: Human
    Sample Types: Whole Blood
  47. Antibiotic-induced microbiome perturbations are associated with significant alterations to colonic mucosal immunity in rhesus macaques
    Authors: JA Manuzak, AS Zevin, R Cheu, B Richardson, J Modesitt, T Hensley-Mc, C Miller, AT Gustin, E Coronado, T Gott, M Fang, M Cartwright, S Wangari, B Agricola, D May, E Smith, HB Hampel, M Gale, CM Cameron, MJ Cameron, J Smedley, NR Klatt
    Mucosal Immunol, 2019-12-04;0(0):.
    Species: Human
    Sample Types: Plasma
  48. Prebiotic UG1601 mitigates constipation-related events in association with gut microbiota: A randomized placebo-controlled intervention study
    Authors: JR Chu, SY Kang, SE Kim, SJ Lee, YC Lee, MK Sung
    World J. Gastroenterol., 2019-10-28;25(40):6129-6144.
    Species: Human
    Sample Types: Serum
  49. Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests
    Authors: N Aziz, R Detels, JJ Quint, D Gjertson, T Ryner, AW Butch
    BMC Immunol., 2019-09-14;20(1):33.
    Species: Human
    Sample Types: Serum
  50. Predictors of Obesity among Gut Microbiota Biomarkers in African American Men with and without Diabetes
    Authors: E Barengolts, SJ Green, GE Chlipala, BT Layden, Y Eisenberg, M Priyadarsh, LR Dugas
    Microorganisms, 2019-09-05;7(9):.
    Species: Human
    Sample Types: Serum
  51. Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis
    Authors: DT Claiborne, EP Scully, CD Palmer, JL Prince, GN Macharia, J Kopycinski, CM Michelo, HW Wiener, R Parker, K Nganou-Mak, D Douek, M Altfeld, J Gilmour, MA Price, J Tang, W Kilembe, SA Allen, E Hunter
    PLoS Pathog., 2019-08-26;15(8):e1007981.
    Species: Human
    Sample Types: Plasma
  52. Pretransplant Levels of C-Reactive Protein,�Soluble TNF Receptor-1, and�CD38+HLADR+ CD8 T Cells Predict Risk of Allograft Rejection in HIV+ Kidney Transplant Recipients
    Authors: JF Camargo, S Pallikkuth, I Moroz, Y Natori, ML Alcaide, A Rodriguez, G Guerra, GW Burke, S Pahwa
    Kidney Int Rep, 2019-08-19;4(12):1705-1716.
    Species: Human
    Sample Types: Plamsa
  53. Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1
    Authors: C Missailidi, N Sørensen, S Ashenafi, W Amogne, E Kassa, A Bekele, M Getachew, N Gebreselas, A Aseffa, G Aderaye, J Andersson, S Brighenti, P Bergman
    Nutrients, 2019-07-21;11(7):.
    Species: Human
    Sample Types: Plasma
  54. Bacterial Translocation and Host Immune Activation in Chronic Hepatitis C Infection
    Authors: MS Moon, G Quinn, EC Townsend, RO Ali, GY Zhang, A Bradshaw, K Hill, H Guan, D Hamilton, DE Kleiner, C Koh, T Heller
    Open Forum Infect Dis, 2019-07-01;6(7):.
    Species: Human
    Sample Types: Serum
  55. Evolving understanding of cardiovascular, cerebrovascular and peripheral arterial disease in people living with HIV and role of novel biomarkers. A study of the Spanish CoRIS cohort, 2004-2015
    Authors: M Masiá, S Padilla, JA García, J García-Abe, M Fernández, I Bernardino, M Montero, J Peraire, B Pernas, F Gutiérrez
    PLoS ONE, 2019-04-26;14(4):e0215507.
    Species: Human
    Sample Types: Plasma
  56. TLR9 polymorphism correlates with immune activation, CD4 decline and plasma IP10 levels in HIV patients
    Authors: A Joshi, EB Punke, T Mehmetoglu, DP Peralta, H Garg
    BMC Infect. Dis., 2019-01-16;19(1):56.
    Species: Human
    Sample Types: Plasma
  57. Enrichment of gut-derived Fusobacterium is associated with suboptimal immune recovery in HIV-infected individuals
    Authors: SC Lee, LL Chua, SH Yap, TF Khang, CY Leng, RI Raja Azwa, SR Lewin, A Kamarulzam, YL Woo, YAL Lim, P Loke, R Rajasuriar
    Sci Rep, 2018-09-24;8(1):14277.
    Species: Human
    Sample Types: Plasma
  58. HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers
    Authors: R Sharaf, GQ Lee, X Sun, B Etemad, LM Aboukhater, Z Hu, ZL Brumme, E Aga, RJ Bosch, Y Wen, G Namazi, C Gao, EP Acosta, RT Gandhi, JM Jacobson, D Skiest, DM Margolis, R Mitsuyasu, P Volberding, E Connick, DR Kuritzkes, MM Lederman, XG Yu, M Lichterfel, JZ Li
    J. Clin. Invest., 2018-08-20;0(0):.
    Species: Human
    Sample Types: Plasma
  59. Marital distress, depression, and a leaky gut: Translocation of bacterial endotoxin as a pathway to inflammation
    Authors: JK Kiecolt-Gl, SJ Wilson, ML Bailey, R Andridge, J Peng, LM Jaremka, CP Fagundes, WB Malarkey, B Laskowski, MA Belury
    Psychoneuroendocrinology, 2018-08-04;98(0):52-60.
    Species: Human
    Sample Types: Serum
  60. The CD14 (-159 C/T) SNP is associated with sCD14 levels and allergic asthma, but not with CD14 expression on monocytes
    Authors: JJ Nieto-Font, FJ Salgado, ME San-José, MJ Cruz, A Casas-Fern, MJ Gómez-Cond, L Valdés-Cua, MÁ García-Gon, P Arias, M Nogueira, FJ González-B
    Sci Rep, 2018-03-07;8(1):4147.
    Species: Human
    Sample Types: Serum
  61. The NLRP3 Inflammasome Is Upregulated in HIV-Infected Antiretroviral Therapy-Treated Individuals with Defective Immune Recovery
    Authors: A Bandera, M Masetti, M Fabbiani, M Biasin, A Muscatello, N Squillace, M Clerici, A Gori, D Trabattoni
    Front Immunol, 2018-02-12;9(0):214.
    Species: Human
    Sample Types: Plasma
  62. Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment
    Authors: SJ Bissel, K Gurnsey, HP Jedema, NF Smith, G Wang, CW Bradberry, CA Wiley
    Retrovirology, 2018-02-01;15(1):17.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Plasma Rich Growth Factors
  63. Prior to extension, Transcriptomes of fibroblast-like Synoviocytes from extended and Polyarticular juvenile idiopathic arthritis are indistinguishable
    Authors: AC Brescia, MM Simonds, SM McCahan, KE Sullivan, CD Rose
    Pediatr Rheumatol Online J, 2018-01-08;16(1):3.
    Species: Human
    Sample Types: Synovial Fluid
  64. Monocyte activation detected prior to a diagnosis of schizophrenia in the US Military New Onset Psychosis Project (MNOPP)
    Authors: NS Weber, KL Gressitt, DN Cowan, DW Niebuhr, RH Yolken, EG Severance
    Schizophr. Res., 2018-01-06;0(0):.
    Species: Human
    Sample Types: Serum
  65. A Pilot Study of Immune Activation and Rifampin Absorption in HIV-Infected Patients without Tuberculosis Infection: A Short Report
    Authors: C Vinnard, I Manley, B Scott, M Bernui, J Adams, S Varghese, I Zentner, MA Kutzler
    Tuberc Res Treat, 2017-12-21;2017(0):2140974.
    Species: Human
    Sample Types: Plasma
  66. Elevated Neopterin Levels Predict Early Death in Older Hip-fracture Patients
    Authors: M Larsen, C Bayard, H Lepetitcor, J Cohen-Bitt, V Appay, J Boddaert, D Sauce
    EBioMedicine, 2017-11-06;0(0):.
    Species: Human
    Sample Types: Plasma
  67. Reevaluation of immune activation in the era of cART and an aging HIV-infected population
    Authors: LR de Armas, S Pallikkuth, V George, S Rinaldi, R Pahwa, KL Arheart, S Pahwa
    JCI Insight, 2017-10-19;2(20):.
    Species: Human
    Sample Types: Plasma
  68. Prospective Analysis of Lipid Composition Changes with Antiretroviral Therapy and Immune Activation in Persons Living with HIV
    Authors: MA Belury, E Bowman, J Gabriel, B Snyder, M Kulkarni, M Palettas, X Mo, JE Lake, D Zidar, SF Sieg, B Rodriguez, MP Playford, A Andrade, DR Kuritzkes, NN Mehta, MM Lederman, NT Funderburg
    Pathog Immun, 2017-10-06;2(3):376-403.
    Species: Human
    Sample Types: Plasma
  69. Impact of monotherapy on HIV-1 reservoir, immune activation, and co-infection with Epstein-Barr virus
    Authors: MR Petrara, AM Cattelan, L Sasset, R Freguja, F Carmona, S Sanavia, M Zanchetta, P Del Bianco, A De Rossi
    PLoS ONE, 2017-09-19;12(9):e0185128.
    Species: Human
    Sample Types: Plasma
  70. Quantity of alcohol drinking positively correlates with serum levels of endotoxin and markers of monocyte activation
    Authors: S Liangpunsa, E Toh, RA Ross, LE Heathers, K Chandler, A Oshodi, B McGee, E Modlik, T Linton, D Mangiacarn, C Jimenez, XC Dong, L Wang, W Tu, DE Nelson
    Sci Rep, 2017-06-30;7(1):4462.
    Species: Human
    Sample Types: Serum
  71. Changes in inflammatory biomarkers in HCV-infected patients undergoing direct acting antiviral-containing regimens with or without interferon
    Authors: C Mascia, S Vita, P Zuccalà, R Marocco, T Tieghi, S Savinelli, R Rossi, M Iannetta, I Pozzetto, C Furlan, F Mengoni, CM Mastroiann, V Vullo, M Lichtner
    PLoS ONE, 2017-06-21;12(6):e0179400.
    Species: Human
    Sample Types: Plasma
  72. Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease
    Authors: YK Yong, HY Tan, SH Jen, EM Shankar, SK Natkunam, J Sathar, R Manikam, SD Sekaran
    J Transl Med, 2017-05-31;15(1):121.
    Species: Human
    Sample Types: Plasma
  73. Association of Anisocytosis with Markers of Immune Activation and Exhaustion in Treated HIV
    Authors: SG Al-Kindi, DA Zidar, GA McComsey, CT Longenecke
    Pathog Immun, 2017-05-02;2(1):138-150.
    Species: Human
    Sample Types: Plasma
  74. Plasma IP-10 Concentrations Correlate Positively with Viraemia and Inversely with CD4 Counts in Untreated HIV Infection
    Authors: K Mhandire, T Mlambo, LS Zijenah, K Duri, K Mateveke, M Tshabalala, DZ Mhandire, C Musarurwa, PT Wekare, LR Mazengera, HT Matarira, B Stray-Pede
    Open AIDS J, 2017-04-26;11(0):24-31.
    Species: Human
    Sample Types: Plasma
  75. Impact of probiotic Saccharomyces boulardii on the gut microbiome composition in HIV-treated patients: A double-blind, randomised, placebo-controlled trial
    Authors: J Villar-Gar, R Güerri-Fer, A Moya, A González, JJ Hernández, E Lerma, A Guelar, L Sorli, JP Horcajada, A Artacho, G D Auria, H Knobel
    PLoS ONE, 2017-04-07;12(4):e0173802.
    Species: Human
    Sample Types: Serum
  76. Lower Baseline Germinal Center Activity and Preserved Th1 Immunity Are Associated With Hepatitis B Vaccine Response in Treated HIV Infection
    Authors: RM Paris, LG Milagres, E Moysi, JF Okulicz, BK Agan, A Ganesan, C Petrovas, RA Koup
    Pathog Immun, 2017-03-14;2(1):66-88.
    Species: Human
    Sample Types: Plasma
  77. Fecal Bacterial Communities in treated HIV infected individuals on two antiretroviral regimens
    Authors: S Pinto-Card, C Lozupone, O Briceño, S Alva-Herná, N Téllez, A Adriana, A Murakami-O, G Reyes-Terá
    Sci Rep, 2017-03-06;7(0):43741.
    Species: Human
    Sample Types: Plasma
  78. Interleukin-1 receptor antagonist, a biomarker of response to anti-TB treatment in HIV/TB co-infected patients
    Authors: J Nouhin, P Pean, Y Madec, MF Chevalier, C Didier, L Borand, FX Blanc, D Scott-Alga, D Laureillar, L Weiss
    J. Infect, 2017-02-09;0(0):.
    Species: Human
    Sample Types: Plasma
  79. Lack of effect of Maraviroc intensification on blood and gut reservoir
    Authors: Juan Tiraboschi
    AIDS Res. Hum. Retroviruses, 2017-02-01;0(0):.
    Species: Human
    Sample Types: Plasma
  80. Cerebrospinal fluid microglia and neurodegenerative markers in twins concordant and discordant for psychotic disorders
    Authors: Viktoria Johansson
    Eur Arch Psychiatry Clin Neurosci, 2016-12-30;0(0):.
    Species: Human
    Sample Types: CSF
  81. Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption
    Authors: Sandra E Dross
    J. Immunol, 2016-12-14;0(0):.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Plasma
  82. Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication
    PLoS Pathog, 2016-12-07;12(12):e1006048.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Plasma
  83. Increased cell-free mitochondrial DNA is a marker of ongoing inflammation and better neurocognitive function in virologically suppressed HIV-infected individuals
    Authors: Josué Pérez-Sant
    J. Neurovirol, 2016-12-05;0(0):.
    Species: Human
    Sample Types: Plasma
  84. Immune Activation and Bacterial Translocation: A Link between Impaired Immune Recovery and Frequent Visceral Leishmaniasis Relapses in HIV-Infected Patients
    PLoS ONE, 2016-12-01;11(12):e0167512.
    Species: Human
    Sample Types: Plasma
  85. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
    Authors: Valentina Cecchinato
    J. Immunol, 2016-11-28;0(0):.
    Species: Human
    Sample Types: Plasma
  86. Immune Activation at Sites of HIV/TB Co-Infection Contributes to the Pathogenesis of HIV-1 Disease
    PLoS ONE, 2016-11-21;11(11):e0166954.
    Species: Human
    Sample Types: Complex Sample Type, Plasma
  87. Soluble CD14 inhibits contractile function and insulin action in primary adult rat cardiomyocytes
    Authors: D Margriet Ouwens
    Biochim. Biophys. Acta, 2016-11-03;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  88. Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection
    Authors: M Kulkarni, E Bowman, J Gabriel, T Amburgy, E Mayne, DA Zidar, C Maierhofer, AN Turner, JA Bazan, SL Koletar, MM Lederman, SF Sieg, NT Funderburg
    Open Forum Infect Dis, 2016-10-15;3(4):ofw224.
    Species: Human
    Sample Types: Plasma
  89. Immunity in young adult survivors of childhood leukemia is more similar to elderly rather than age-matched controls: Role of cytomegalovirus (CMV)
    Eur J Immunol, 2016-05-19;0(0):.
    Species: Human
    Sample Types: Plasma
  90. HCV Specific IL-21 Producing T Cells but Not IL-17A Producing T Cells Are Associated with HCV Viral Control in HIV/HCV Coinfection
    PLoS ONE, 2016-04-28;11(4):e0154433.
    Species: Human
    Sample Types: Plasma
  91. P2X7 Receptor Inhibition Improves CD34 T-Cell Differentiation in HIV-Infected Immunological Nonresponders on c-ART
    Authors: I Menkova-Ga, H Hocini, E Foucat, P Tisserand, L Bourdery, C Delaugerre, C Benne, Y Lévy, JD Lelièvre
    PLoS Pathog, 2016-04-15;12(4):e1005571.
    Species: Human
    Sample Types: Plasma
  92. Bacteroides are associated with GALT iNKT cell function and reduction of microbial translocation in HIV-1 infection
    Authors: D Paquin-Pro, C Ching, I Vujkovic-C, D Fadrosh, L Loh, Y Huang, M Somsouk, SV Lynch, PW Hunt, DF Nixon, D SenGupta
    Mucosal Immunol, 2016-04-06;0(0):.
    Species: Human
    Sample Types: Plasma
  93. Widespread activation of immunity and pro-inflammatory programs in peripheral blood leukocytes of HIV-infected patients with impaired lung gas exchange
    Authors: K Crothers, I Petrache, C Wongtrakoo, PJ Lee, LM Schnapp, SA Gharib
    Physiol Rep, 2016-04-01;4(8):.
    Species: Human
    Sample Types: Serum
  94. Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques.
    Authors: Pandrea I, Xu C, Stock J, Frank D, Ma D, Policicchio B, He T, Kristoff J, Cornell E, Haret-Richter G, Trichel A, Ribeiro R, Tracy R, Wilson C, Landay A, Apetrei C
    PLoS Pathog, 2016-01-14;12(1):e1005384.
    Species: Human, Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
    Sample Types: Plasma
  95. Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins.
    Authors: Lakritz J, Robinson J, Polydefkis M, Miller A, Burdo T
    J Neuroinflammation, 2015-12-18;12(0):237.
    Species: Primate
    Sample Types: Plasma
  96. Late Antiretroviral Therapy (ART) Initiation Is Associated with Long-Term Persistence of Systemic Inflammation and Metabolic Abnormalities.
    Authors: Ghislain M, Bastard J, Meyer L, Capeau J, Fellahi S, Gerard L, May T, Simon A, Vigouroux C, Goujard C
    PLoS ONE, 2015-12-04;10(12):e0144317.
    Species: Human
    Sample Types: Serum
  97. Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption.
    Authors: Rothenberger, Meghan K, Keele, Brandon, Wietgrefe, Stephen, Fletcher, Courtney, Beilman, Gregory, Chipman, Jeffrey, Khoruts, Alexande, Estes, Jacob D, Anderson, Jodi, Callisto, Samuel P, Schmidt, Thomas E, Thorkelson, Ann, Reilly, Cavan, Perkey, Katherin, Reimann, Thomas G, Utay, Netanya, Nganou Makamdop, Krystell, Stevenson, Mario, Douek, Daniel C, Haase, Ashley T, Schacker, Timothy
    Proc Natl Acad Sci U S A, 2015-02-23;112(10):E1126-34.
    Species: Human
    Sample Types: Plasma
  98. Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression.
    Authors: Claiborne, Daniel T, Prince, Jessica, Scully, Eileen, Macharia, Gladys, Micci, Luca, Lawson, Benton, Kopycinski, Jakub, Deymier, Martin J, Vanderford, Thomas H, Nganou-Makamdop, Krystell, Ende, Zachary, Brooks, Kelsie, Tang, Jianming, Yu, Tianwei, Lakhi, Shabir, Kilembe, William, Silvestri, Guido, Douek, Daniel, Goepfert, Paul A, Price, Matthew, Allen, Susan A, Paiardini, Mirko, Altfeld, Marcus, Gilmour, Jill, Hunter, Eric
    Proc Natl Acad Sci U S A, 2015-02-17;112(12):E1480-9.
    Species: Human
    Sample Types: Plasma
  99. The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial.
    Authors: Somsouk, Ma, Dunham, Richard, Cohen, Michelle, Albright, Rebecca, Abdel-Mohsen, Mohamed, Liegler, Teri, Lifson, Jeffrey, Piatak, Michael, Gorelick, Robert, Huang, Yong, Wu, Yuaner, Hsue, Priscill, Martin, Jeffrey, Deeks, Steven G, McCune, Joseph M, Hunt, Peter W
    PLoS ONE, 2014-12-29;9(12):e116306.
    Species: Human
    Sample Types: Plasma
  100. Elevated plasma soluble CD14 and skewed CD16+ monocyte distribution persist despite normalisation of soluble CD163 and CXCL10 by effective HIV therapy: a changing paradigm for routine HIV laboratory monitoring?
    Authors: Castley, Alison, Berry, Cassandr, French, Martyn, Fernandez, Sonia, Krueger, Romano, Nolan, David
    PLoS ONE, 2014-12-29;9(12):e115226.
    Species: Human
    Sample Types: Plasma
  101. Shift in monocyte apoptosis with increasing viral load and change in apoptosis-related ISG/Bcl2 family gene expression in chronically HIV-1-infected subjects.
    Authors: Patro S, Pal S, Bi Y, Lynn K, Mounzer K, Kostman J, Davuluri R, Montaner L
    J Virol, 2014-10-29;89(1):799-810.
    Species: Human
    Sample Types: Plasma
  102. Coinfection with human herpesvirus 8 is associated with persistent inflammation and immune activation in virologically suppressed HIV-infected patients.
    Authors: Masia M, Robledano C, Ortiz de la Tabla V, Antequera P, Lumbreras B, Hernandez I, Gutierrez F
    PLoS ONE, 2014-08-18;9(8):e105442.
    Species: Human
    Sample Types: Plasma
  103. Progressive proximal-to-distal reduction in expression of the tight junction complex in colonic epithelium of virally-suppressed HIV+ individuals.
    Authors: Chung, Charlott, Alden, Stephani, Funderburg, Nicholas, Fu, Pingfu, Levine, Alan D
    PLoS Pathog, 2014-06-26;10(6):e1004198.
    Species: Human
    Sample Types: Plasma
  104. Pathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts.
    Authors: Mandell D, Kristoff J, Gaufin T, Gautam R, Ma D, Sandler N, Haret-Richter G, Xu C, Aamer H, Dufour J, Trichel A, Douek D, Keele B, Apetrei C, Pandrea I
    J Virol, 2014-04-02;88(12):6778-92.
    Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
    Sample Types: Plasma
  105. Reduced IgM levels and elevated IgG levels against oxidized low-density lipoproteins in HIV-1 infection.
    Authors: Yilmaz A, Jennbacken K, Fogelstrand L
    BMC Infect Dis, 2014-03-17;14(0):143.
    Species: Human
    Sample Types: Plasma
  106. Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild.
    Authors: Ma, Dongzhu, Jasinska, Anna J, Feyertag, Felix, Wijewardana, Viskam, Kristoff, Jan, He, Tianyu, Raehtz, Kevin, Schmitt, Christop, Jung, Yoon, Cramer, Jennifer, Dione, Michel, Antonio, Martin, Tracy, Russell, Turner, Trudy, Robertson, David L, Pandrea, Ivona, Freimer, Nelson, Apetrei, Cristian
    J Virol, 2014-03-12;88(10):5687-705.
    Species: Human
    Sample Types: Plasma
  107. Plasma sCD14 as a biomarker to predict pulmonary exacerbations in cystic fibrosis.
    Authors: Quon B, Ngan D, Wilcox P, Man S, Sin D
    PLoS ONE, 2014-02-20;9(2):e89341.
    Species: Human
    Sample Types: Plasma
  108. Activation of NK cells is associated with HIV-1 disease progression.
    Authors: Kuri-Cervantes L, de Oca G, Avila-Rios S, Hernandez-Juan R, Reyes-Teran G
    J Leukoc Biol, 2014-01-07;96(1):7-16.
    Species: Human
    Sample Types: Plasma
  109. Dynamics of immune reconstitution and activation markers in HIV+ treatment-naive patients treated with raltegravir, tenofovir disoproxil fumarate and emtricitabine.
    Authors: Funderburg N, Andrade A, Chan E, Rosenkranz S, Lu D, Clagett B, Pilch-Cooper H, Rodriguez B, Feinberg J, Daar E, Mellors J, Kuritzkes D, Jacobson J, Lederman M
    PLoS ONE, 2013-12-18;8(12):e83514.
    Species: Human
    Sample Types: Plasma
  110. Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.
    Authors: Hatano, Hiroyu, Yukl, Steven A, Ferre, April L, Graf, Erin H, Somsouk, Ma, Sinclair, Elizabet, Abdel-Mohsen, Mohamed, Liegler, Teri, Harvill, Kara, Hoh, Rebecca, Palmer, Sarah, Bacchetti, Peter, Hunt, Peter W, Martin, Jeffrey, McCune, Joseph M, Tracy, Russell, Busch, Michael, O'Doherty, Una, Shacklett, Barbara, Wong, Joseph K, Deeks, Steven G
    PLoS Pathog, 2013-10-10;9(10):e1003691.
    Species: Human
    Sample Types: Plasma
  111. Predictive value of liver enzymes and inflammatory biomarkers for the severity of liver fibrosis stage in HIV/HCV co-infected patients.
    Authors: Charpentier C, Champenois K, Gervais A, Landman R, Joly V, Le Gac S, Larrouy L, Damond F, Brun-Vezinet F, Descamps D, Yazdanpanah Y
    PLoS ONE, 2013-03-19;8(3):e59205.
    Species: Human
    Sample Types: Plasma
  112. Transcriptional effects of 1,25 dihydroxyvitamin D(3) physiological and supra-physiological concentrations in breast cancer organotypic culture.
    Authors: Milani C, Katayama M, de Lyra E, Welsh J, Campos L, Brentani M, Maciel M, Roela R, del Valle P, Goes J, Nonogaki S, Tamura R, Folgueira M
    BMC Cancer, 2013-03-15;13(0):119.
    Species: Human
    Sample Types: Cell Culture Supernates
  113. Decreased IL-7 responsiveness is related to oxidative stress in HIV disease.
    Authors: Kalinowska M, Bazdar D, Lederman M, Funderburg N, Sieg S
    PLoS ONE, 2013-03-07;8(3):e58764.
    Species: Human
    Sample Types: Serum
  114. SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations.
    Authors: Ma, Dongzhu, Jasinska, Anna, Kristoff, Jan, Grobler, J Paul, Turner, Trudy, Jung, Yoon, Schmitt, Christop, Raehtz, Kevin, Feyertag, Felix, Martinez Sosa, Natalie, Wijewardana, Viskam, Burke, Donald S, Robertson, David L, Tracy, Russell, Pandrea, Ivona, Freimer, Nelson, Apetrei, Cristian
    PLoS Pathog, 2013-01-17;9(1):e1003011.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Types: Plasma
  115. Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.
    Authors: Broadhurst, Mara Jan, Ardeshir, Amir, Kanwar, Bittoo, Mirpuri, Julie, Gundra, Uma Mahe, Leung, Jacqueli, Wiens, Kirsten, Vujkovic-Cvijin, Ivan, Kim, Charlie, Yarovinsky, Felix, Lerche, Nicholas, McCune, Joseph M
    Oncogene, 2012-11-15;8(11):e1003000.
    Species: Human
    Sample Types: Plasma
  116. Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome.
    Authors: Funderburg, Nicholas, Zidar, David A, Shive, Carey, Lioi, Anthony, Mudd, Joseph, Musselwhite, Laura W, Simon, Daniel I, Costa, Marco A, Rodriguez, Benigno, Sieg, Scott F, Lederman, Michael
    Blood, 2012-10-11;120(23):4599-608.
    Species: Human
    Sample Types: Plasma
  117. Relationship between microbial translocation and endothelial function in HIV infected patients.
    Authors: Blodget E, Shen C, Aldrovandi G, Rollie A, Gupta S, Stein J, Dube M
    PLoS ONE, 2012-08-30;7(8):e42624.
    Species: Human
    Sample Types: Plasma
  118. CD4 T follicular helper cell dynamics during SIV infection.
    J. Clin. Invest., 2012-08-27;122(9):3281-94.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Plasma
  119. Altered monocyte activation markers in Tourette's syndrome: a case-control study.
    Authors: Matz J, Krause DL, Dehning S, Riedel M, Gruber R, Schwarz MJ, Muller N
    BMC Psychiatry, 2012-05-18;12(0):29.
    Species: Human
    Sample Types: Serum
  120. The relationship of systemic inflammation to prior hospitalization in adult patients with cystic fibrosis.
    Authors: Ngan D, Wilcox P, Aldaabil M, Li Y, Leipsic J, Sin D, Man S
    BMC Pulm Med, 2012-02-14;12(0):3.
    Species: Human
    Sample Types: Plasma
  121. Epithelial adhesion molecules can inhibit HIV-1-specific CD8+ T-cell functions.
    Authors: Streeck H, Kwon DS, Pyo A, Flanders M, Chevalier MF, Law K, Julg B, Trocha K, Jolin JS, Anahtar MN, Lian J, Toth I, Brumme Z, Chang JJ, Caron T, Rodig SJ, Milner DA, Piechoka-Trocha A, Kaufmann DE, Walker BD, Altfeld M
    Blood, 2011-03-14;117(19):5112-22.
    Species: Human
    Sample Types: Plasma
  122. Maternal country of origin, breast milk characteristics and potential influences on immunity in offspring.
    Authors: Holmlund U, Amoudruz P, Johansson MA, Haileselassie Y, Ongoiba A, Kayentao K, Traore B, Doumbo S, Schollin J, Doumbo O, Montgomery SM, Sverremark-Ekstrom E
    Clin. Exp. Immunol., 2010-10-05;162(3):500-9.
    Species: Human
    Sample Types: Milk
  123. Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection.
    Authors: Ford ES, Greenwald JH, Richterman AG
    AIDS, 2010-06-19;24(10):1509-17.
    Species: Human
    Sample Types: Plasma
  124. Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation.
    Authors: Funderburg NT, Mayne E, Sieg SF
    Blood, 2009-10-14;115(2):161-7.
    Species: Human
    Sample Types: Plasma
  125. Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion.
    Authors: Pandrea I, Gaufin T, Brenchley JM, Gautam R, Monjure C, Gautam A, Coleman C, Lackner AA, Ribeiro RM, Douek DC, Apetrei C
    J. Immunol., 2008-11-15;181(10):6687-91.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Types: Plasma
  126. Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population.
    Authors: Miller MA, McTernan PG, Harte AL, Silva NF, Strazzullo P, Alberti KG, Kumar S, Cappuccio FP
    Atherosclerosis, 2008-07-01;203(2):494-502.
    Species: Human
    Sample Types: Plasma
  127. Breast milk fatty acids may link innate and adaptive immune regulation: analysis of soluble CD14, prostaglandin E2, and fatty acids.
    Authors: Laitinen K, Hoppu U, Hamalainen M, Linderborg K, Moilanen E, Isolauri E
    Pediatr. Res., 2006-05-01;59(5):723-7.
    Species: Human
    Sample Types: Serum
  128. CD14 is an acute-phase protein.
    Authors: Bas S, Gauthier BR, Spenato U, Stingelin S, Gabay C
    J. Immunol., 2004-04-01;172(7):4470-9.
    Species: Human
    Sample Types: Serum
  129. Reduced interferon gamma production and soluble CD14 levels in early life predict recurrent wheezing by 1 year of age.
    Authors: Guerra S, Lohman IC, Halonen M, Martinez FD, Wright AL
    Am. J. Respir. Crit. Care Med., 2003-10-02;169(1):70-6.
    Species: Human
    Sample Types: Serum
  130. TGF-beta in human milk is associated with wheeze in infancy.
    Authors: Oddy WH, Halonen M, Martinez FD, Lohman IC, Stern DA, Kurzius-Spencer M, Guerra S, Wright AL
    J. Allergy Clin. Immunol., 2003-10-01;112(4):723-8.
    Species: Human
    Sample Types: Milk

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Reviews for Human CD14 Quantikine ELISA Kit

Average Rating: 4.7 (Based on 9 Reviews)

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Human CD14 Quantikine ELISA Kit
By Jonathan Sturgeon on 03/22/2021
Sample Tested: EDTA Plasma

Great kit frequently used. R2 on standard curve >0.999 (attached). Recommended.

Human CD14 Quantikine ELISA Kit DC140
Human CD14 Quantikine ELISA Kit
By Anonymous on 03/17/2021
Sample Tested: Cerebrospinal Fluid,Serum
Human CD14 Quantikine ELISA Kit DC140
Human CD14 Quantikine ELISA Kit
By Anonymous on 11/13/2020
Sample Tested: Human serum

Easy to follow protocol.

Human CD14 Quantikine ELISA Kit DC140
Human CD14 Quantikine ELISA Kit
By APK Inmunometabolismo on 11/06/2020
Sample Tested: Cell culture supernatant
Human CD14 Quantikine ELISA Kit DC140
Human CD14 Quantikine ELISA Kit
By Anonymous on 10/03/2018
Sample Tested: EDTA Plasma
Human CD14 Quantikine ELISA Kit DC140
Human CD14 Quantikine ELISA Kit
By Anonymous on 10/03/2018
Sample Tested: EDTA Plasma
Human CD14 Quantikine ELISA Kit DC140
Human CD14 Quantikine ELISA Kit
By Leslie Priddy on 03/30/2018
Sample Tested: Serum
Human CD14 Quantikine ELISA Kit
By Anonymous on 02/08/2017
Sample Tested: Human EDTA plasma
Human CD14 Quantikine ELISA Kit DC140
Human CD14 Quantikine ELISA Kit
By Anonymous on 12/15/2016
Sample Tested: EDTA Plasma

Plasma was isolated from blood drawn in EDTA tubes from HIV+/ART subjects and from healthy HIV- controls. sCD14 levels were measured in plasma using the Quantikine elisa Human sCD14 kit (cat# DC140). Plasma was diluted 1:200 before use in assay. Assay was carried out according to protocol provided in kit.

Figure legends:
a)Standard curve for sCD14 from which plasma sCD14 values were extrapolated.
b)Quantitated data from HIV+/ART and healthy subjects measured using the kit.

Results are expressed in ng/ml and significance calculated using unpaired Mann Whitney U-test.

Human CD14 Quantikine ELISA Kit DC140