Human ERR gamma/NR3B3 Antibody

Catalog # Availability Size / Price Qty
PP-H6812-00
Product Details
Citations (10)
FAQs
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Human ERR gamma/NR3B3 Antibody Summary

Species Reactivity
Human
Source
Monoclonal Mouse IgG2a Clone # H6812
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ERR gamma/NR3B3

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Usher's syndrome.

Long Name
Estrogen-related Receptor gamma
Entrez Gene IDs
2104 (Human)
Alternate Names
DKFZp781L1617; ERR gamma; ERR gamma-2; ERR3; ERRG2; ERRgamma; ESRRG; Estrogen receptor-related protein 3; estrogen-related receptor gamma; FLJ16023; KIAA0832; NR3B3; Nuclear receptor subfamily 3 group B member 3

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Citations for Human ERR gamma/NR3B3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

10 Citations: Showing 1 - 10
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  1. ERR?-inducible FGF23 promotes alcoholic liver injury through enhancing CYP2E1 mediated hepatic oxidative stress
    Authors: Jung, YS;Radhakrishnan, K;Hammad, S;Müller, S;Müller, J;Noh, JR;Kim, J;Lee, IK;Cho, SJ;Kim, DK;Kim, YH;Lee, CH;Dooley, S;Choi, HS;
    Redox biology
    Species: Viral, Murine polyomavirus strain A3
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  2. ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control
    Authors: MN Khan, P Cherukuri, F Negro, A Rajput, P Fabrowski, V Bansal, C Lancelin, TI Lee, Y Bian, WP Mayer, T Akay, D Müller, S Bonn, D Farina, T Marquardt
    PloS Biology, 2022-12-21;20(12):e3001923.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  3. An Inverse Agonist GSK5182 Increases Protein Stability of the Orphan Nuclear Receptor ERRgamma via Inhibition of Ubiquitination
    Authors: SY Na, KS Kim, YS Jung, DK Kim, J Kim, SJ Cho, IK Lee, J Chung, JS Kim, HS Choi
    International Journal of Molecular Sciences, 2022-12-21;24(1):.
    Species: Human, Mouse
    Sample Types: Cell Lysates, Protein
    Applications: IHC, Immunoprecipitation
  4. Spinal Motoneuron TMEM16F Acts at C-boutons to Modulate Motor Resistance and Contributes to ALS Pathogenesis
    Authors: C Soulard, C Salsac, K Mouzat, C Hilaire, J Roussel, A Mezghrani, S Lumbroso, C Raoul, F Scamps
    Cell Rep, 2020-02-25;30(8):2581-2593.e7.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. Origin and Segmental Diversity of Spinal Inhibitory Interneurons
    Authors: LB Sweeney, JB Bikoff, MI Gabitto, S Brenner-Mo, M Baek, JH Yang, EG Tabak, JS Dasen, CR Kintner, TM Jessell
    Neuron, 2018-01-04;0(0):.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  6. Hypoxia Induces PDK4 Gene Expression through Induction of the Orphan Nuclear Receptor ERRgamma.
    Authors: Lee J, Kim E, Kim D, Lee J, Park S, Lee I, Harris R, Lee M, Choi H
    PLoS ONE, 2012-09-25;7(9):e46324.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP, Western Blot
  7. Estrogen-related receptor gamma (ERRgamma) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling.
    Authors: Kim DK, Kim JR, Koh M, Kim YD, Lee JM, Chanda D, Park SB, Min JJ, Lee CH, Park TS, Choi HS
    J. Biol. Chem., 2011-09-12;286(44):38035-42.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  8. Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation.
    Authors: Xie YB, Park JH, Kim DK, Hwang JH, Oh S, Park SB, Shong M, Lee IK, Choi HS
    J. Biol. Chem., 2009-08-18;284(42):28762-74.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation
  9. Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells.
    Authors: Spector NL, Yarden Y, Smith B, Lyass L, Trusk P, Pry K, Hill JE, Xia W, Seger R, Bacus SS
    Proc. Natl. Acad. Sci. U.S.A., 2007-06-07;104(25):10607-12.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  10. ERRgamma suppresses cell proliferation and tumor growth of androgen-sensitive and androgen-insensitive prostate cancer cells and its implication as a therapeutic target for prostate cancer.
    Authors: Yu S, Wang X, Ng CF, Chen S, Chan FL
    Cancer Res., 2007-05-15;67(10):4904-14.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot

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