Human FAK (NP_722560.1) VersaClone cDNA

Human FAK (NP_722560.1) VersaClone cDNA Summary

Specifications

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Background: FAK

FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation. Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness.

Related Research Areas

• Adhesion Molecules on Endothelial Cells
• Adhesion Molecules on VSMC
• Chemokine Receptor Intracellular Signaling
• Focal Adhesions
• GDNF Family
• Intracellular Kinases in the Akt Pathway
• Intracellular Signaling Molecules in Angiogenesis
• Kinases and Phosphatases in Endothelial Cells
• Kinases and Phosphatases in VSMC
• Mesenchymal Cells and EMT
• Repulsive Guidance Molecules and Receptors
• VEGF Family