Human GPR31 (EAW47505) VersaClone cDNA

Catalog #: RDC0645 Datasheet / COA / SDS

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RDC0645

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Human GPR31 (EAW47505) VersaClone cDNA Summary

Specifications

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: GPR31

GPR31 is a plasma membrane G protein-coupled receptor (GPCR) that displays high affinity for 12-lipoxygenase-derived product 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-(S)-HETE). Knocking down GPR31 specifically inhibited 12-(S)-HETE-stimulated cell invasion. The diverse biological activities mediated by 12-(S)-HETE suggest that it functions as a critical signaling molecule in the regulation of physiological processes. 12-(S)-HETE/GPR31 binding leads to the activation of ERK1/2, MEK, and NF-kB.

Long Name

G-Protein-Coupled Receptor 31

Entrez Gene IDs

2853 (Human); 436440 (Mouse); 292310 (Rat)

Alternate Names

12-HETER; bA517H2.2 (G protein-coupled receptor 31); G protein-coupled receptor 31; GPR31; HETER1; probable G-protein coupled receptor 31

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