Human GR/NR3C1 Antibody (Clone H8031)

Name: Human GR/NR3C1 Antibody (Clone H8031)
Brand: R&D Systems
SKU: PP-H8031-00
Rating: 5 (1 reviews)

Catalog #: PP-H8031-00 1 Review Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
PP-H8031-00

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human GR/NR3C1 Antibody (Clone H8031) Summary

Species Reactivity

Human

Source

Monoclonal Mouse IgG2a Clone # H8031

Formulation

A liquid formulation in physiologic saline with 0.1% NaN₃.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: GR/NR3C1

Glucocorticoid receptor (GR; NR3C1) is a member of the steroid receptor family. GR are expressed in almost all human tissues and organs. GR bind to its sequences as a homodimer. Two different forms, GR-alpha and GR-beta, differing in their C-terminal parts were isolated. GR-alpha is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GR-beta does not bind glucocorticoids.

Long Name

Glucocorticoid Receptor

Entrez Gene IDs

2908 (Human)

Alternate Names

GCR; glucocorticoid receptor; GR; GRGCCR; GRLNuclear receptor subfamily 3 group C member 1; NR3C1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); nuclear receptor subfamily 3, group C, member 1