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Human ICAM-1/CD54 (NP_000192) VersaClone cDNA

Catalog #: RDC1030
2 Citations Datasheet / COA / SDS
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RDC1030
R&D Systems VersaClone cDNA Plasmids
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Human ICAM-1/CD54 (NP_000192) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: ICAM-1/CD54

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.

Long Name
Intercellular Adhesion Molecule 1
Entrez Gene IDs
3383 (Human); 15894 (Mouse); 25464 (Rat)
Alternate Names
BB2; CD54 antigen; CD54; cell surface glycoprotein P3.58; human rhinovirus receptor; ICAM1; ICAM-1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule 1; Major group rhinovirus receptor; P3.58

Citations for Human ICAM-1/CD54 (NP_000192) VersaClone cDNA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Construction of a Vero Cell Line Expressing Human ICAM1 for the Development of Rhinovirus Vaccines
    Authors: WJP van den Br, B Monica, D Limpens, D Rockx-Brou, M de Boer, D Oosterhoff
    Viruses, 2022-10-12;14(10):.  2022-10-12
  2. NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis
    Authors: K Saga, J Park, K Nimura, N Kawamura, A Ishibashi, N Nonomura, Y Kaneda
    J. Exp. Clin. Cancer Res., 2019-10-16;38(1):416.  2019-10-16

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