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Human IL-8/CXCL8 Antibody

Catalog #: MAB208
180 Citations 10 Reviews Datasheet / COA / SDS
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MAB208-SP
MAB208-100
MAB208-500
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Detection of Human IL-8/CXCL8 by Western Blot.
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Citations (180)
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Reviews (10)
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Human IL-8/CXCL8 Antibody Summary

Species Reactivity
Human
Specificity
Detects human IL-8/CXCL8 in ELISAs and Western blots. In Western blots, 100% cross-reactivity with recombinant porcine IL-8/CXCL8 and no cross-reactivity with recombinant rat CXCL3/CINC-2 alpha is observed.
Source
Monoclonal Mouse IgG1 Clone # 6217
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human IL-8/CXCL8
Ser28-Ser99
Accession # P10145
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
3 µg/mL
THP‑1 human acute monocytic leukemia cell line treated (+) with PMA and LPS
Simple Western
50 µg/mL
Human PBMC conditioned media treated with LPS
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Immunocytochemistry
8-25 µg/mL
See below
Intracellular Staining by Flow Cytometry
0.25 µg/106 cells
Human peripheral blood mononuclear cells treated with LPS, fixed with paraformaldehyde, and permeabilized with saponin

Human IL-8/CXCL8 Sandwich Immunoassay

Recommended Concentration
Reagent
ELISA Capture (Matched Antibody Pair)
2-8 µg/mL 

Use in combination with:

Detection Reagent: Human IL-8/CXCL8 Biotinylated Antibody (Catalog # BAF208)

Standard: Recombinant Human IL-8/CXCL8 Protein (Catalog # 208-IL)

Neutralization
Measured by its ability to neutralize IL-8/CXCL8-induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CXCR2. The Neutralization Dose (ND50) is typically 0.08-0.4 µg/mL in the presence of 20 ng/mL Recombinant Human IL-8/CXCL8.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot View Larger

Detection of Human IL-8/CXCL8 by Western Blot. Western blot shows lysates of THP‑1 human acute monocytic leukemia cell line untreated (-) or treated (+) with 200 nM PMA and 10 ug/mL LPS for 24 hours and 3 hours. PVDF membrane was probed with 3 µg/mL of Mouse Anti-Human IL-8/CXCL8 Monoclonal Antibody (Catalog # MAB208) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (HAF018). A specific band was detected for IL-8/CXCL8 at approximately 10 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1.

Immunocytochemistry IL-8/CXCL8 antibody in Human PBMCs by Immunocytochemistry (ICC). View Larger

IL-8/CXCL8 in Human PBMCs. IL-8/CXCL8 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) using Mouse Anti-Human IL-8/CXCL8 Monoclonal Antibody (Catalog # MAB208) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Simple Western Detection of Human IL-8/CXCL8 antibody by Simple Western<sup>TM</sup>. View Larger

Detection of Human IL-8/CXCL8 by Simple WesternTM. Simple Western lane view shows human PBMC conditioned media untreated (-) or treated (+) with 1 μg/mL LPS for 24 hrs, loaded at 0.2 mg/mL. A specific band was detected for IL-8/CXCL8 at approximately 8 kDa (as indicated) using 50 µg/mL of Mouse Anti-Human IL-8/CXCL8 Monoclonal Antibody (Catalog # MAB208). This experiment was conducted under reducing conditions and using the 2-40 kDa separation system.

Neutralization Chemotaxis Induced by IL-8/CXCL8 and Neutralization by Human IL-8/CXCL8 Antibody. View Larger

Chemotaxis Induced by IL-8/CXCL8 and Neutralization by Human IL-8/CXCL8 Antibody. Recombinant Human IL-8/CXCL8 (Catalog # 208-IL) chemoattracts the BaF3 mouse pro-B cell line transfected with human CXCR2 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Human IL-8/CXCL8 (20 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human IL-8/CXCL8 Monoclonal Antibody (Catalog # MAB208). The ND50 is typically 0.08-0.4 µg/mL.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-8/CXCL8

CXCL8, also known as IL-8, is a CXC chemokine that is a potent chemoattractant for neutrophils and has a wide range of other pro-inflammatory effects.

Long Name
Interleukin 8
Entrez Gene IDs
3576 (Human); 396880 (Porcine); 403850 (Canine); 493836 (Feline)
Alternate Names
3-10C; AMCF-I; C-X-C motif chemokine 8; CXCL8; CXCL8SCYB8; Emoctakin; GCP1; GCP-1TSG-1; IL8; IL-8; interleukin 8; K60; LAI; LECT; LUCT; LYNAP; MDNCF; MDNCFb-ENAP; member 8; MONAP; MONAPGCP1; NAF; NAP1; NAP-1NAP1; NCF; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; TCF; TSG1

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Citations for Human IL-8/CXCL8 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

180 Citations: Showing 1 - 10
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  1. Novel Function of Cancer Stem Cell Marker ALDH1A3 in Glioblastoma: Pro-Angiogenesis through Paracrine PAI-1 and IL-8
    Authors: Chen Z, Will R, Kim SN et al.
    Cancers (Basel)
  2. Short-term EGFR blockade enhances immune-mediated cytotoxicity of EGFR mutant lung cancer cells: rationale for combination therapies
    Authors: Charli Dominguez, Kwong-Yok Tsang, Claudia Palena
    Cell Death & Disease
  3. Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition
    Authors: Mahito Sadaie, Christian Dillon, Masako Narita, Masashi Narita, Andrew R J Young, Claire J Cairney et al.
    Molecular Biology of the Cell
  4. Interleukin-8 Secreted by Glioblastoma Cells Induces Microvascular Hyperpermeability Through NO Signaling Involving S-Nitrosylation of VE-Cadherin and p120 in Endothelial Cells
    Authors: Anita Guequén, Patricia Zamorano, Francisco Córdova, Tania Koning, Angelo Torres, Pamela Ehrenfeld et al.
    Frontiers in Physiology
  5. Pathogen Evasion of Chemokine Response Through Suppression of CXCL10
    Authors: Alejandro L. Antonia, Kyle D. Gibbs, Esme D. Trahair, Kelly J. Pittman, Amelia T. Martin, Benjamin H. Schott et al.
    Frontiers in Cellular and Infection Microbiology
  6. Multiplexed protein analysis using encoded antibody-conjugated microbeads
    Authors: Nora Theilacker, Eric E. Roller, Kristopher D. Barbee, Matthias Franzreb, Xiaohua Huang
    Journal of The Royal Society Interface
  7. The GAG-Binding Peptide MIG30 Protects against Liver Ischemia-Reperfusion in Mice
    Authors: Thiago Henrique Caldeira Oliveira, Vincent Vanheule, Sofie Vandendriessche, Fariba Poosti, Mauro Martins Teixeira, Paul Proost et al.
    International Journal of Molecular Sciences
  8. Cholesterol crystals induce inflammatory cytokines expression in a human retinal pigment epithelium cell line by activating the NF-kappa B pathway
    Authors: Yijun Hu, Haijiang Lin, Bernard Dib, Alp Atik, Peggy Bouzika, Christopher Lin et al.
    Discov Med
  9. Loss of androgen receptor signaling in prostate cancer‐associated fibroblasts (CAFs) promotes CCL2‐ and CXCL8‐mediated cancer cell migration
    Authors: Bianca Cioni, Ekaterina Nevedomskaya, Monique H. M. Melis, Johan van Burgsteden, Suzan Stelloo, Emma Hodel et al.
    Molecular Oncology
  10. Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis
    Authors: Sugong Chen, Robert C. Fisher, Steven Signs, L. Alex Molina, Anitha K. Shenoy, Maria-Cecilia Lopez et al.
    Oncotarget
  11. Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage
    Authors: Juan Antonio Fafián-Labora, Jose Antonio Rodríguez-Navarro, Ana O’Loghlen
    Cell Metabolism
  12. Biological Characterization of Commercial Recombinantly Expressed Immunomodulating Proteins Contaminated with Bacterial Products in the Year 2020: The SAA3 Case
    Authors: S Abouelasra, M De Bondt, N Berghmans, M Gouwy, VLS de Oliveir, SC Oliveira, FA Amaral, P Proost, J Van Damme, S Struyf, M De Buck
    Mediators Inflamm., 2020-07-06;2020(0):6087109.
  13. IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib
    Authors: Romaine I. Fernando, Duane H. Hamilton, Charli Dominguez, Justin M. David, Kristen K. McCampbell, Claudia Palena
    Oncotarget
  14. A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment
    Authors: R. C. Cornelison, J. X. Yuan, K. M. Tate, A. Petrosky, G. F. Beeghly, M. Bloomfield et al.
    npj Precision Oncology
  15. Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response
    Authors: Edmée Eyraud, Elise Maurat, Jean-Marc Sac-Epée, Pauline Henrot, Maeva Zysman, Pauline Esteves et al.
    eLife
  16. CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells
    Authors: Amy Sinclair, Laura Park, Mansi Shah, Mark Drotar, Simon Calaminus, Lisa E. M. Hopcroft et al.
    Blood
  17. Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation
    Authors: Britt-Marie Sundblad, Britt-Marie Sundblad, Bettina Levänen, Bettina Midander, Anneli Midander, Anneli Julander et al.
    International Journal of Chronic Obstructive Pulmonary Disease
  18. SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells
    Authors: Hoai-Nga Thi Nguyen, Marie Kawahara, Cat-Khanh Vuong, Mizuho Fukushige, Toshiharu Yamashita, Osamu Ohneda
    Frontiers in Oncology
  19. Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers
    Authors: Pamela J. Maxwell, Melanie McKechnie, Christopher W. Armstrong, Judith M. Manley, Chee Wee Ong, Jenny Worthington et al.
    Molecular Cancer Research
  20. Cystathionine-beta -synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation
    Authors: Haoran Zhu, Keefe T Chan, Xinran Huang, Carmelo Cerra, Shaun Blake, Anna S Trigos et al.
    eLife
  21. ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade
    Authors: Valerio Ciccone, Erika Terzuoli, Emma Ristori, Arianna Filippelli, Marina Ziche, Lucia Morbidelli et al.
    International Journal of Molecular Medicine
  22. Synergism between Hedgehog-GLI and EGFR Signaling in Hedgehog-Responsive Human Medulloblastoma Cells Induces Downregulation of Canonical Hedgehog-Target Genes and Stabilized Expression of GLI1
    Authors: Frank Götschel, Daniela Berg, Wolfgang Gruber, Christian Bender, Markus Eberl, Myriam Friedel et al.
    PLoS ONE
  23. The Dominant Role of IL-8 as an Angiogenic Driver in a Three-Dimensional Physiological Tumor Construct for Drug Testing
    Authors: Pamela H.S. Tan, Su Shin Chia, Siew Lok Toh, James C.H. Goh, Saminathan Suresh Nathan
    Tissue Engineering Part A
  24. High tumor levels of IL6 and IL8 abrogate preclinical efficacy of the gamma -secretase inhibitor, RO4929097
    Authors: Wei He, Leopoldo Luistro, Daisy Carvajal, Melissa Smith, Tom Nevins, Xuefeng Yin et al.
    Molecular Oncology
  25. Serum Amyloid A1 (SAA1) Revisited: Restricted Leukocyte-Activating Properties of Homogeneous SAA1
    Authors: Sara Abouelasrar Salama, Mirre De Bondt, Mieke De Buck, Nele Berghmans, Paul Proost, Vivian Louise Soares Oliveira et al.
    Frontiers in Immunology
  26. CAR T-Cells Targeting the Integrin alpha v beta 6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies
    Authors: Lynsey M. Whilding, Leena Halim, Benjamin Draper, Ana C. Parente-Pereira, Tomasz Zabinski, David Marc Davies et al.
    Cancers (Basel)
  27. A novel microRNA-182/Interleukin-8 regulatory axis controls osteolytic bone metastasis of lung cancer
    Authors: Ming-Na Zhao, Ling-Fei Zhang, Zhen Sun, Li-Hua Qiao, Tao Yang, Yi-Zhe Ren et al.
    Cell Death & Disease
  28. Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance
    Authors: Kelvin Yin, Daniel Patten, Sarah Gough, Susana de Barros Gonçalves, Adelyne Chan, Ioana Olan et al.
    Genes & Development
  29. Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts
    Authors: A Krishnamur, AJ Ytterberg, M Sun, K Sakuraba, J Steen, V Joshua, NK Tarasova, V Malmström, H Wähämaa, B Réthi, AI Catrina
    J. Immunol., 2019-04-24;0(0):.
  30. ERK3/MAPK6 controls IL-8 production and chemotaxis
    Authors: Katarzyna Bogucka, Malvika Pompaiah, Federico Marini, Harald Binder, Gregory Harms, Manuel Kaulich et al.
    eLife
  31. MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8
    Authors: Dipa Bhaumik, Gary K. Scott, Shiruyeh Schokrpur, Christopher K. Patil, Arturo V. Orjalo, Francis Rodier et al.
    ImpactJ
  32. Chemokine receptor engineering of T cells with CXCR2 improves homing towards subcutaneous human melanomas in xenograft mouse model
    Authors: Manja Idorn, Signe Koggersbøl Skadborg, Lauge Kellermann, Hólmfrídur Rósa Halldórsdóttir, Gitte Holmen Olofsson, Özcan Met et al.
    OncoImmunology
  33. Induction of Chemokines by Hepatitis C Virus Proteins: Synergy of the Core Protein with Interleukin-1 beta and Interferon-gamma in Liver Bystander Cells
    Authors: Sara Abouelasrar Salama, Mieke Gouwy, Alexandra De Zutter, Noëmie Pörtner, Lotte Vanbrabant, Nele Berghmans et al.
    Journal of Interferon & Cytokine Research
  34. The Cytoprotective Effects of Human Endothelial Progenitor Cell-Conditioned Medium against an Ischemic Insult Are Not Dependent on VEGF and IL-8
    Authors: Stefano Di Santo, Anna-Lena Fuchs, Ramesh Periasamy, Stefanie Seiler, Hans Rudolf Widmer
    Cell Transplantation
  35. Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
    Authors: Akilan Krishnamurthy, Vijay Joshua, Aase Haj Hensvold, Tao Jin, Meng Sun, Nancy Vivar et al.
    Annals of the Rheumatic Diseases
  36. Application of the Mirrorball High-Sensitivity Cytometer to Multiplexed Assays for Antibody Drug Discovery
    Authors: Elizabeth England, Philip Newton, Frances Neal, Lisa Kitching, Caroline Colley, Christine J. Rossant
    J Biomol Screen
  37. Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival
    Authors: M Dietachmay, A Rathakrish, O Karpiuk, F von Zweydo, T Engleitner, V Fernández-, P Schenk, M Ueffing, R Rad, M Eilers, CJ Gloeckner, K Clemm von, F Bassermann
    Nat Commun, 2020-03-09;11(1):1268.
  38. Bone marrow-derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition.
    Authors: Pietrovito L, Leo A, Gori V et al.
    Mol Oncol.
  39. Acceleration of clear cell renal cell carcinoma growth in mice following bevacizumab/Avastin treatment: the role of CXCL cytokines
    Authors: R Grepin, M Guyot, M Jacquin, J Durivault, E Chamorey, A Sudaka et al.
    Oncogene
  40. Protein kinase D1-mediated classical protein secretory pathway regulates oncogene Ras-induced senescent response
    Authors: Y Su, P Wang, H Shen, Z Sun, C Xu, G Li, T Tong, J Chen
    J. Cell. Sci., 2018-03-16;0(0):.
  41. Interleukin‑8 released by cancer‑associated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells
    Authors: Suyanee Thongchot, Pranisa Jamjuntra, Suwanit Therasakvichya, Malee Warnnissorn, Alessandra Ferraresi, Peti Thuwajit et al.
    International Journal of Oncology
  42. Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet Allotransplantation
    Authors: Maria Hårdstedt, Susanne Lindblom, Alex Karlsson-Parra, Bo Nilsson, Olle Korsgren
    Cell Transplantation
  43. Catecholamines Promote Ovarian Cancer Progression through Secretion of CXC-Chemokines
    Authors: Kim, HJ;Chang, HK;Lee, YM;Heo, K;
    International journal of molecular sciences
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  44. Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation
    Authors: Shen, CJ;Chan, RH;Lin, BW;Li, NC;Huang, YH;Chang, WC;Chen, BK;
    Theranostics
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  45. Suppression of TGF beta -Induced Interleukin-6 Secretion by Sinulariolide from Soft Corals through Attenuation of the p38-NF-kB Pathway in Carcinoma Cells
    Authors: Yang, JL;Lin, WL;Tai, SB;Ciou, YS;Chung, CL;Chen, JJ;Liu, PF;Lin, MW;Chen, CL;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  46. High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer
    Authors: Fu, X;Pereira, R;Liu, CC;De Angelis, C;Shea, MJ;Nanda, S;Qin, L;Mitchell, T;Cataldo, ML;Veeraraghavan, J;Sethunath, V;Giuliano, M;Gutierrez, C;Győrffy, B;Trivedi, MV;Cohen, O;Wagle, N;Nardone, A;Jeselsohn, R;Rimawi, MF;Osborne, CK;Schiff, R;
    Cell reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  47. IL8 derived from macrophages inhibits CD8+ T-cell function by downregulating TIM3 expression through IL8-CXCR2 axis in patients with advanced colorectal cancer
    Authors: Zhao, C;Wang, D;Li, Z;Zhang, Z;Xu, Y;Liu, J;Lei, Q;Han, D;Huo, Y;Liu, S;Li, L;Zhang, Y;
    International immunopharmacology
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC, Neutralization
  48. Discovery of senolytics using machine learning
    Authors: Smer-Barreto, V;Quintanilla, A;Elliott, RJR;Dawson, JC;Sun, J;Campa, VM;Lorente-Macías, Á;Unciti-Broceta, A;Carragher, NO;Acosta, JC;Oyarzún, DA;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  49. Gastric cancer cell-originated small extracellular vesicle induces metabolic reprogramming of BM-MSCs through ERK-PPAR?-CPT1A signaling to potentiate lymphatic metastasis
    Authors: Huang, J;Wang, X;Wen, J;Zhao, X;Wu, C;Wang, L;Cao, X;Dong, H;Xu, X;Huang, F;Zhu, W;Wang, M;
    Cancer cell international
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  50. RanBP1: A Potential Therapeutic Target for Cancer Stem Cells in Lung Cancer and Glioma
    Authors: YJ Kahm, IG Kim, RK Kim
    International Journal of Molecular Sciences, 2023-04-06;24(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  51. Effect of teriparatide on drug treatment of tuberculous spondylitis: an experimental study
    Authors: S Lee, YJ Seo, JY Choi, X Che, HJ Kim, SY Eum, MS Hong, SK Lee, DC Cho
    Scientific Reports, 2022-12-15;12(1):21667.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Capture
  52. CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype
    Authors: W Zeng, L Xiong, W Wu, S Li, J Liu, L Yang, L Lao, P Huang, M Zhang, H Chen, N Miao, Z Lin, Z Liu, X Yang, J Wang, P Wang, E Song, Y Yao, Y Nie, J Chen, D Huang
    Oncogene, 2022-11-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  53. Modeling human HSV infection via a vascularized immune-competent skin-on-chip platform
    Authors: S Sun, L Jin, Y Zheng, J Zhu
    Nature Communications, 2022-09-19;13(1):5481.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Neutralization
  54. The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells
    Authors: MF Santolla, M Talia, F Cirillo, D Scordamagl, S De Rosis, A Spinelli, AM Miglietta, B Nardo, G Filippelli, EM De Frances, A Belfiore, R Lappano, M Maggiolini
    Cells, 2022-08-04;11(15):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance
    Authors: R Islam, J Mishra, NS Polavaram, S Bhattachar, Z Hong, S Bodas, S Sharma, A Bouska, T Gilbreath, AM Said, LM Smith, BA Teply, MH Muders, SK Batra, K Datta, S Dutta
    Oncogene, 2022-07-19;40(3):111097.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  56. Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
    Authors: T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen, F Tran, P Griebel, D Albrecht, A Ahmed, M Suarez-Car, A Jiménez-Sá, T Beikert, A Tietz-Dahl, AN Menevse, G Schmidt, M Brom, JHW Pahl, W Antonopoul, M Miller, RL Perez, F Bestvater, NA Giese, P Beckhove, P Rosenstiel, D Jäger, O Strobel, D Pe'er, N Halama, J Debus, A Cerwenka, PE Huber
    Science Advances, 2022-03-23;8(12):eabh4050.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  57. Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence
    Authors: E Lieschke, Z Wang, C Chang, CE Weeden, GL Kelly, A Strasser
    Cell Death and Differentiation, 2022-03-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  58. Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4
    Authors: F Yang, XQ Liu, JZ He, SP Xian, PF Yang, ZY Mai, M Li, Y Liu, XD Zhang
    Journal of Cellular and Molecular Medicine, 2022-02-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy
    Authors: RM Urbantat, C Jelgersma, S Brandenbur, M Nieminen-K, I Kremenetsk, J Zollfrank, S Mueller, K Rubarth, A Koch, P Vajkoczy, G Acker
    International Journal of Molecular Sciences, 2021-10-16;22(20):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  60. Extracellular Hsp90alpha Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer
    Authors: Q Hou, S Chen, Q An, B Li, Y Fu, Y Luo
    International Journal of Molecular Sciences, 2021-07-20;22(14):.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: Co-Immunoprecipitation, ICC, IHC, Western Blot
  61. COX2 regulates senescence secretome composition and senescence surveillance through PGE2
    Authors: S Gonçalves, K Yin, Y Ito, A Chan, I Olan, S Gough, L Cassidy, E Serrao, S Smith, A Young, M Narita, M Hoare
    Cell Reports, 2021-03-16;34(11):108860.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  62. Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair
    Authors: H Israelov, O Ravid, D Atrakchi, D Rand, S Elhaik, Y Bresler, R Twitto-Gre, L Omesi, S Liraz-Zalt, F Gosselet, M Schnaider, I Cooper
    J Neuroinflammation, 2020-09-09;17(1):267.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  63. Chemotherapy-induced IL-8 upregulates MDR1/ABCB1 in tumor blood vessels and results in unfavorable outcome
    Authors: H Kikuchi, N Maishi, DA Annan, M Towfik Ala, R Ibrahim Ha, M Sato, M Morimoto, R Takeda, K Ishizuka, R Matsumoto, T Akino, K Tsuchiya, T Abe, T Osawa, N Miyajima, S Maruyama, T Harabayash, M Azuma, K Yamashiro, K Ameda, A Kashiwagi, Y Matsuno, Y Hida, N Shinohara, K Hida
    Cancer Res., 2020-06-14;0(0):.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: IHC, Neutralization
  64. Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
    Authors: Q Ji, L Zhou, H Sui, L Yang, X Wu, Q Song, R Jia, R Li, J Sun, Z Wang, N Liu, Y Feng, X Sun, G Cai, Y Feng, J Cai, Y Cao, G Cai, Y Wang, Q Li
    Nat Commun, 2020-03-05;11(1):1211.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  65. Microenvironmental IL1beta promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
    Authors: R Eyre, DG Alférez, A Santiago-G, K Spence, JC McConnell, C Hart, BM Simões, D Lefley, C Tulotta, J Storer, A Gurney, N Clarke, M Brown, SJ Howell, AH Sims, G Farnie, PD Ottewell, RB Clarke
    Nat Commun, 2019-11-01;10(1):5016.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  66. Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells
    Authors: LM Ashander, S Lie, Y Ma, E Rochet, JM Washington, JM Furtado, B Appukuttan, JR Smith
    Invest. Ophthalmol. Vis. Sci., 2019-11-01;60(14):4652-4660.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  67. Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization
    Authors: A Schulz, L Jiang, L de Vor, M Ehrström, F Wermeling, L Eidsmo, K Melican
    Cell Rep, 2019-10-29;29(5):1074-1081.e5.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Blocking
  68. TCR- or Cytokine-Activated CD8+ Mucosal-Associated Invariant T Cells Are Rapid Polyfunctional Effectors That Can Coordinate Immune Responses
    Authors: R Lamichhane, M Schneider, SM de la Harp, TWR Harrop, RF Hannaway, PK Dearden, JR Kirman, JDA Tyndall, AJ Vernall, JE Ussher
    Cell Rep, 2019-09-17;28(12):3061-3076.e5.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  69. Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3
    Authors: M Borghesan, J Fafián-Lab, O Eleftheria, P Carpintero, M Paez-Ribes, G Vizcay-Bar, A Swisa, D Kolodkin-G, P Ximénez-Em, R Lowe, B Martín-Mar, H Peinado, J Muñoz, RA Fleck, Y Dor, I Ben-Porath, A Vossenkamp, D Muñoz-Espi, A O'Loghlen
    Cell Rep, 2019-06-25;27(13):3956-3971.e6.
    Species: Human
    Sample Types: Cell Lysates, Extracellular Vesicles
    Applications: ICC, Western Blot
  70. Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging
    Authors: DP Muñoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lope, M Kawahara, AM Freund, F Rodier, JD Wu, PY Desprez, DH Raulet, PS Nelson, LJ van 't Vee, J Campisi, JP Coppé
    JCI Insight, 2019-06-11;5(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  71. The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection
    Authors: L Miarka, C Hauser, O Helm, D Holdhof, S Beckinger, JH Egberts, JP Gundlach, L Lenk, S Rahn, W Mikulits, A Trauzold, S Sebens
    Cancers (Basel), 2019-05-29;11(6):.
    Species: Human
    Sample Types: Transfected Whole Cells
    Applications: Neutralization
  72. Differentiated fibrocytes assume a functional mesenchymal phenotype with regenerative potential
    Authors: C Ling, K Nishimoto, Z Rolfs, LM Smith, BL Frey, NV Welham
    Sci Adv, 2019-05-08;5(5):eaav7384.
    Species: Rat
    Sample Types: In Vivo
    Applications: Bioassay
  73. Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity
    Authors: EP Reeves, DM Dunlea, K McQuillan, CA O'Dwyer, TP Carroll, R Saldova, PR Akepati, MR Wormald, OJ McElvaney, V Shutchaida, M Henry, P Meleady, J Keenan, DC Liberti, DN Kotton, PM Rudd, AA Wilson, NG McElvaney
    J. Immunol., 2019-02-22;0(0):.
    Species: Human
    Sample Types: Protein
    Applications: Binding Assay
  74. Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth
    Authors: J Zhang, H Li, Q Wu, Y Chen, Y Deng, Z Yang, L Zhang, B Liu
    Redox Biol, 2019-02-06;22(0):101116.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Neutralization
  75. Varicella Zoster Virus Induces Differential Cell-Type Specific Responses in Human Corneal Epithelial Cells and Keratocytes
    Authors: CN Como, AN Bubak, AM Blackmon, D Jones, NH Mueller, R Davidson, MA Nagel
    Invest. Ophthalmol. Vis. Sci., 2019-02-01;60(2):704-711.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  76. L-selectin expression is regulated by CXCL8-induced reactive oxygen species produced during human neutrophil rolling
    Authors: MJ Domínguez-, E Armas-Gonz, A Herrera-Ga, M Arce-Franc, M Feria, M Vicente-Ma, A Martínez-R, F Sánchez-Ma, F Díaz-Gonzá
    Eur. J. Immunol., 2018-12-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  77. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
    Authors: SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali
    Nat Commun, 2018-08-15;9(1):3267.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  78. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases
    Authors: B Gril, AN Paranjape, S Woditschka, E Hua, EL Dolan, J Hanson, X Wu, W Kloc, E Izycka-Swi, R Duchnowska, R P?ksa, W Biernat, J Jassem, N Nayyar, PK Brastianos, OM Hall, CJ Peer, WD Figg, GT Pauly, C Robinson, S Difilippan, E Bialecki, P Metellus, JP Schneider, PS Steeg
    Psychoneuroendocrinology, 2018-07-13;9(1):2705.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  79. ShRNA-mediated knock-down of CXCL8 inhibits tumor growth in colorectal liver metastasis
    Authors: A Kumar, M Cherukumil, SH Mahmoudpou, K Brand, OR Bandapalli
    Biochem. Biophys. Res. Commun., 2018-04-23;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  80. DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis
    Authors: Q Liu, A Li, S Yu, S Qin, N Han, RG Pestell, X Han, K Wu
    J Hematol Oncol, 2018-04-10;11(1):53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Age-Related Changes to Human Tear Composition
    Authors: A Micera, A Di Zazzo, G Esposito, R Longo, W Foulsham, R Sacco, R Sgrulletta, S Bonini
    Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2024-2031.
    Species: Human
    Sample Types: Tears
    Applications: Western Blot
  82. Intestinal mucin activates human dendritic cells and IL-8 production in a glycan-specific manner
    Authors: F Melo-Gonza, TM Fenton, C Forss, C Smedley, A Goenka, AS MacDonald, DJ Thornton, MA Travis
    J. Biol. Chem., 2018-03-26;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  83. Galectin-3 is an amplifier of the interleukin-1?-mediated inflammatory response in corneal keratinocytes
    Authors: Y Uchino, AM Woodward, J Mauris, K Peterson, P Verma, UJ Nilsson, J Rajaiya, P Argüeso
    Immunology, 2018-02-15;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Western Blot
  84. HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome
    Authors: S di Martino, CA Amoreo, B Nuvoli, R Galati, S Strano, F Facciolo, G Alessandri, HI Pass, G Ciliberto, G Blandino, R De Maria, M Cioce
    Oncogene, 2018-01-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Inhibition
  85. Endothelial cell leptin receptors, leptin and interleukin-8 in the pathogenesis of preeclampsia: An in-vitro study
    Authors: S Arl?er
    Turk J Obstet Gynecol, 2017-12-30;14(4):220-227.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  86. Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease
    Authors: J Ikari, AJ Nelson, J Obaid, A Giron-Mart, K Ikari, F Makino, S Iwasawa, Y Gunji, M Farid, X Wang, H Basma, D Demeo, C Feghali-Bo, O Holz, K Rabe, X Liu, SI Rennard
    PLoS ONE, 2017-09-07;12(9):e0184039.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development (Capture)
  87. Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease
    Authors: MM White, P Geraghty, E Hayes, S Cox, W Leitch, B Alfawaz, GM Lavelle, OJ McElvaney, R Flannery, J Keenan, P Meleady, M Henry, M Clynes, C Gunaratnam, NG McElvaney, EP Reeves
    EBioMedicine, 2017-08-16;23(0):173-184.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Development (Capture)
  88. Human adipose-derived mesenchymal stem cell-secreted CXCL1 and CXCL8 facilitate breast tumor growth by promoting angiogenesis
    Authors: Y Wang, J Liu, Q Jiang, J Deng, F Xu, X Chen, F Cheng, Y Zhang, Y Yao, Z Xia, X Xu, X Su, M Huang, L Dai, Y Yang, S Zhang, D Yu, RC Zhao, Y Wei, H Deng
    Stem Cells, 2017-06-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  89. Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells
    Authors: B Tian, A Al-Moujahe, P Bouzika, Y Hu, S Notomi, P Tsoka, JW Miller, H Lin, DG Vavvas
    Sci Rep, 2017-05-24;7(1):2329.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  90. Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling
    Authors: HB Song, HO Jun, JH Kim, YH Lee, MH Choi, JH Kim
    PLoS ONE, 2017-04-13;12(4):e0175159.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Neutralization
  91. Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells
    Authors: J Liu, G Song, X Lin, X Pang, T Meng
    Exp Ther Med, 2017-02-21;13(4):1447-1455.
    Species: Human
    Sample Types: Whole Cells
    Applications: Functional Assay
  92. Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation
    Authors: CM Henry, SJ Martin
    Mol. Cell, 2017-02-16;65(4):715-729.e5.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  93. Histone Deacetylase (HDAC) Inhibition Induces I?B Kinase (IKK)-dependent Interleukin-8/CXCL8 Expression in Ovarian Cancer Cells
    Authors: HR Gatla, Y Zou, MM Uddin, B Singha, P Bu, A Vancura, I Vancurova
    J. Biol. Chem., 2017-02-06;292(12):5043-5054.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  94. Novel augmentation by bufalin of protein kinase C-induced cyclooxygenase-2 and IL-8 production in human breast cancer cells
    Authors: Yuh-Lin Wu
    Innate Immun, 2016-11-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Human pancreatic cancer cells induce a MyD88-dependent stromal response to promote a tumor-tolerant immune microenvironment
    Cancer Res., 2016-11-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells
    Int J Mol Sci, 2016-08-19;17(8):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  97. NOTCH1 mediates a switch between two distinct secretomes during senescence
    Authors: M Hoare, Y Ito, TW Kang, MP Weekes, NJ Matheson, DA Patten, S Shetty, AJ Parry, S Menon, R Salama, R Antrobus, K Tomimatsu, W Howat, PJ Lehner, L Zender, M Narita
    Nat. Cell Biol, 2016-08-15;18(9):979-92.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  98. Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells
    Sci Rep, 2016-08-10;6(0):31087.
    Species: Bacteria - E. Coli
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation
  99. The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer
    Authors: Z Jing, H Xu, X Chen, Q Zhong, J Huang, Y Zhang, W Guo, Z Yang, S Ding, P Chen, Z Huang
    PLoS ONE, 2016-04-14;11(4):e0152789.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  100. Chemokine CCL15 Mediates Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Hepatocellular Carcinoma.
    Authors: Gao Y, Zhou Z, Lu S, Huang X, Zhang C, Jiang R, Yao A, Sun B, Wang X
    Stem Cells, 2016-01-13;34(4):1112-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  101. Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop.
    Authors: Chen L, Min L, Wang X, Zhao J, Chen H, Qin J, Chen W, Shen Z, Tang Z, Gan Q, Ruan Y, Sun Y, Qin X, Gu J
    Cancer Res, 2015-07-21;75(18):3832-41.
    Species: Human, Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Neutralization
  102. Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer.
    Authors: Takeuchi S, Baghdadi M, Tsuchikawa T, Wada H, Nakamura T, Abe H, Nakanishi S, Usui Y, Higuchi K, Takahashi M, Inoko K, Sato S, Takano H, Shichinohe T, Seino K, Hirano S
    Cancer Res, 2015-05-07;75(13):2629-40.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Neutralization
  103. Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines.
    Authors: Gouwy M, De Buck M, Portner N, Opdenakker G, Proost P, Struyf S, Van Damme J
    Eur J Immunol, 2014-12-01;45(1):101-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  104. Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition.
    Authors: Voltolini C, Battersby S, Novembri R, Torricelli M, Severi F, Petraglia F, Norman J
    Endocrinology, 2014-11-26;156(2):670-9.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development (Capture)
  105. The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis.
    Authors: McElvaney O, O'Reilly N, White M, Lacey N, Pohl K, Gerlza T, Bergin D, Kerr H, McCarthy C, O'Brien M, Adage T, Kungl A, Reeves E, McElvaney N
    Mol Immunol, 2014-11-02;63(2):550-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk.
    Authors: Kuravi S, McGettrick H, Satchell S, Saleem M, Harper L, Williams J, Rainger G, Savage C
    J Immunol, 2014-05-28;193(1):234-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  107. Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis.
    Authors: Moelants, Eva A V, Loozen, Gitte, Mortier, Anneleen, Martens, Erik, Opdenakker, Ghislain, Mizgalska, Danuta, Szmigielski, Borys, Potempa, Jan, Van Damme, Jo, Teughels, Wim, Proost, Paul
    Infect Immun, 2014-03-31;82(6):2511-9.
    Species: Bacteria - Porphyromonas gingivalis
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development (Detection)
  108. Chemokine CXCL8 promotes HIV-1 replication in human monocyte-derived macrophages and primary microglia via nuclear factor-kappaB pathway.
    Authors: Mamik M, Ghorpade A
    PLoS ONE, 2014-03-24;9(3):e92145.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  109. Interleukin-1-induced activation of the small GTPase Rac1 depends on receptor internalization and regulates gene expression.
    Authors: Windheim M, Hansen B
    Cell Signal, 2013-09-28;26(1):49-55.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  110. CD82/KAI expression prevents IL-8-mediated endothelial gap formation in late-stage melanomas.
    Authors: Khanna, P, Chung, C-Y, Neves, R I, Robertson, G P, Dong, C
    Oncogene, 2013-07-22;33(22):2898-908.
    Species: Human
    Sample Types: Cell Culture Supernates, Cell Lysates
    Applications: ELISA Development (Capture), Western Blot
  111. Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam.
    Authors: Nakajima N, Van Tin N, Sato Y, Thach H, Katano H, Diep P, Kumasaka T, Thuy N, Hasegawa H, San L, Kawachi S, Liem N, Suzuki K, Sata T
    Mod Pathol, 2012-11-23;26(3):357-69.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  112. Macrophages induce differentiation of plasma cells through CXCL10/IP-10.
    J. Exp. Med., 2012-09-17;209(10):1813-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  113. Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
    Authors: Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam T, Leypoldt F, Simova O, Thom V, Friese M, Prinz I, Holscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T
    Blood, 2012-09-13;120(18):3793-802.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  114. Monocytes Induce STAT3 Activation in Human Mesenchymal Stem Cells to Promote Osteoblast Formation.
    Authors: Nicolaidou V, Wong MM, Redpath AN
    PLoS ONE, 2012-07-03;7(7):e39871.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  115. Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages.
    Authors: Meda C, Molla F, De Pizzol M
    J. Immunol., 2012-03-21;188(8):4081-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  116. Daily exposure to dust alters innate immunity.
    Authors: Sahlander K, Larsson K, Palmberg L
    PLoS ONE, 2012-02-15;7(2):e31646.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Development
  117. Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
    Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
    Mucosal Immunol, 2011-12-21;5(2):140-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  118. Protection from RNA and DNA viruses by IL-32.
    Authors: Zepp JA, Nold-Petry CA, Dinarello CA, Nold MF
    J. Immunol., 2011-02-23;186(7):4110-8.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Electrochemiluminescent Assay
  119. TH17 cytokines induce human airway smooth muscle cell migration.
    Authors: Chang Y, Al-Alwan L, Risse PA, Roussel L, Rousseau S, Halayko AJ, Martin JG, Hamid Q, Eidelman DH
    J. Allergy Clin. Immunol., 2011-02-22;127(4):1046-53.e1-2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  120. Suppression of TNF-alpha and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.
    Authors: Kalliolias GD, Gordon RA, Ivashkiv LB
    J. Immunol., 2010-10-22;185(11):7047-56.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  121. Quantitative Validation and Comparison of Multiplex Cytokine Kits
    Authors: Joanna L. Richens, Richard A. Urbanowicz, Rebecca Metcalf, Jonathan Corne, Paul O’Shea, Lucy Fairclough
    J Biomol Screen
  122. Quantitative Validation and Comparison of Multiplex Cytokine Kits
    Authors: Joanna L. Richens, Richard A. Urbanowicz, Rebecca Metcalf, Jonathan Corne, Paul O’Shea, Lucy Fairclough
    J Biomol Screen
  123. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
    Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
    J. Immunol., 2010-03-24;184(0):5263-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  124. IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.
    Authors: Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG
    J. Immunol., 2009-12-21;184(3):1642-52.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  125. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
    Authors: Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, Raza SR, Freund A, Campeau E, Davalos AR, Campisi J
    Nat. Cell Biol., 2009-07-13;11(8):973-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  126. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
    Authors: Hu H, Kwun J, Aizenstein BD, Knechtle SJ
    Transplantation, 2009-06-27;87(12):1814-20.
    Species: Human
    Sample Types: Urine
    Applications: Antibody Array Development
  127. Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.
    Authors: Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009-06-12;297(2):L388-400.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  128. Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma.
    Authors: Osei-Kumah A, Smith R, Clifton VL
    Cytokine, 2008-07-17;43(2):187-93.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Development
  129. IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis.
    Authors: Skov L, Beurskens FJ, Zachariae CO, Reitamo S, Teeling J, Satijn D, Knudsen KM, Boot EP, Hudson D, Baadsgaard O, Parren PW, van de Winkel JG
    J. Immunol., 2008-07-01;181(1):669-79.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  130. Endogenous IL-32 controls cytokine and HIV-1 production.
    Authors: Nold MF, Nold-Petry CA, Pott GB, Zepp JA, Saavedra MT, Kim SH, Dinarello CA
    J. Immunol., 2008-07-01;181(1):557-65.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Electrochemiluminescent Assay
  131. Expression of CXCL8, CXCR1, and CXCR2 in neurons and glial cells of the human and rabbit retina.
    Authors: Goczalik I, Ulbricht E, Hollborn M, Raap M, Uhlmann S, Weick M, Pannicke T, Wiedemann P, Bringmann A, Reichenbach A, Francke M
    Invest. Ophthalmol. Vis. Sci., 2008-06-14;49(10):4578-89.
    Species: Human, Rabbit
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  132. Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
    Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
    J. Clin. Invest., 2007-12-01;117(12):3664-3672.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  133. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines.
    Authors: Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA
    Clin. Chem., 2007-11-01;53(11):2010-2.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Development
  134. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays.
    Authors: Pfleger C, Schloot N, ter Veld F
    J. Immunol. Methods, 2007-10-22;329(1):214-8.
    Species: Human
    Sample Types: Serum
    Applications: Luminex Development
  135. Eotaxin-2 and colorectal cancer: a potential target for immune therapy.
    Authors: Cheadle EJ, Riyad K, Subar D, Rothwell DG, Ashton G, Batha H, Sherlock DJ, Hawkins RE, Gilham DE
    Clin. Cancer Res., 2007-10-01;13(19):5719-28.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: ELISA Development
  136. Ultrasensitive flow-based immunoassays using single-molecule counting.
    Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
    Clin. Chem., 2007-09-21;53(11):1990-5.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Development
  137. Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells.
    Authors: Fitzgerald DC, Meade KG, McEvoy AN, Lillis L, Murphy EP, Machugh DE, Baird AW
    Vet. Immunol. Immunopathol., 2007-01-09;116(1):59-68.
    Species: Bovine
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  138. Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts.
    Authors: Hatfield K, Ryningen A, Corbascio M, Bruserud O
    Int. J. Cancer, 2006-11-15;119(10):2313-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  139. L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion.
    Authors: Abe Y, Fornage M, Yang CY, Bui-Thanh NA, Wise V, Chen HH, Rangaraj G, Ballantyne CM
    Atherosclerosis, 2006-10-04;192(1):56-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  140. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors.
    Authors: Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjostedt A, Edebro H, Forsman M, Bystrom M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK
    Infect. Immun., 2006-09-18;74(12):6730-8.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  141. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.
    Authors: Rofstad EK, Mathiesen B, Kindem K, Galappathi K
    Cancer Res., 2006-07-01;66(13):6699-707.
    Species: Complex Species Category
    Sample Types:
    Applications: Neutralization
  142. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
    Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
    Clin. Immunol., 2006-06-16;120(2):220-31.
    Species: Human
    Sample Types: Blister Fluid, Cell Culture Supernates
    Applications: ELISA Development, Neutralization
  143. Circulating CD34+ progenitor cells modulate host angiogenesis and inflammation in vivo.
    Authors: Popa ER, Harmsen MC, Tio RA, van der Strate BW, Brouwer LA, Schipper M, Koerts J, De Jongste MJ, Hazenberg A, Hendriks M, van Luyn MJ
    J. Mol. Cell. Cardiol., 2006-06-14;41(1):86-96.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  144. PAPP-A and osteoprotegerin, together with interleukin-8 and RANTES, are elevated in the peritoneal fluid of women with endometriosis.
    Authors: Bersinger NA, von Roten S, Wunder DM, Raio L, Dreher E, Mueller MD
    Am. J. Obstet. Gynecol., 2006-04-25;195(1):103-8.
    Species: Human
    Sample Types: Peritoneal Fluid
    Applications: ELISA Development
  145. Proteinase-activated receptor2 agonists upregulate granulocyte colony-stimulating factor, IL-8, and VCAM-1 expression in human bronchial fibroblasts.
    Authors: Ramachandran R, Morice AH, Compton SJ
    Am. J. Respir. Cell Mol. Biol., 2006-02-23;35(1):133-41.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  146. Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells.
    Authors: Edwards MR, Johnson MW, Johnston SL
    Am. J. Respir. Cell Mol. Biol., 2006-01-19;34(5):616-24.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  147. Increased ENA-78 in the follicular fluid of patients with endometriosis.
    Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
    Acta Obstet Gynecol Scand, 2006-01-01;85(3):336-42.
    Species: Human
    Sample Types: Follicular Fluid
    Applications: ELISA Development
  148. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
    Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
    J. Immunol., 2005-11-01;175(9):6177-89.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Neutralization
  149. Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis.
    Authors: Ren Y, Lin CL, Li Z, Chen XY, Huang X, Lui V, Nicholls J, Lan HY, Tam PK
    Histopathology, 2005-06-01;46(6):659-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  150. Interleukin-6 and interleukin-8 in cervical fluid in a population of Swedish women in preterm labor: relationship to microbial invasion of the amniotic fluid, intra-amniotic inflammation, and preterm delivery.
    Authors: Holst RM, Mattsby-Baltzer I, Wennerholm UB, Hagberg H, Jacobsson B
    Acta Obstet Gynecol Scand, 2005-06-01;84(6):551-7.
    Species: Human
    Sample Types: Amniotic Fluid
    Applications: ELISA Development
  151. The activation of IL-8 receptors in cultured guinea pig Muller glial cells is modified by signals from retinal pigment epithelium.
    Authors: Malgorzata Goczalik I, Raap M, Weick M, Milenkovic I, Heidmann J, Enzmann V, Wiedemann P, Reichenbach A, Francke M
    J. Neuroimmunol., 2005-04-01;161(1):49-60.
    Species: Guinea Pig
    Sample Types: Whole Cells
    Applications: ICC
  152. GCP-2/CXCL6 synergizes with other endothelial cell-derived chemokines in neutrophil mobilization and is associated with angiogenesis in gastrointestinal tumors.
    Authors: Penninckx F, Ectors N
    Exp. Cell Res., 2005-02-15;303(2):331-42.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  153. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
    Authors: Phillips TM
    Electrophoresis, 2004-06-01;25(10):1652-9.
    Species: Human
    Sample Types: Serum
    Applications: Affinity Chromatography
  154. 17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells.
    Authors: Bengtsson AK, Ryan EJ, Giordano D, Magaletti DM, Clark EA
    Blood, 2004-05-13;104(5):1404-10.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  155. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
    Authors: Copeland S, Siddiqui J, Remick D
    J. Immunol. Methods, 2004-01-01;284(1):99-106.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Array Development
  156. ELR+ CXC chemokines in human milk.
    Authors: Maheshwari A, Christensen RD, Calhoun DA
    Cytokine, 2003-11-07;24(3):91-102.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  157. Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta.
    Authors: Park JS, 107290, Kim YS, Jee YK, Myong NH, Lee KY
    Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models, 2003-05-01;57(5):463-9.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  158. Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells.
    Authors: Hurst SM, McLoughlin RM, Monslow J, Owens S, Morgan L, Fuller GM, Topley N, Jones SA
    J. Immunol., 2002-11-01;169(9):5244-51.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  159. Expression of functional CCR and CXCR chemokine receptors in podocytes.
    Authors: Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H
    J. Immunol., 2002-06-15;168(12):6244-52.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  160. Metabolic replacement of kidney function in uremic animals with a bioartificial kidney containing human cells.
    Authors: Humes HD, Fissell WH, Weitzel WF, Buffington DA, Westover AJ, MacKay SM, Gutierrez JM
    Am. J. Kidney Dis., 2002-05-01;39(5):1078-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: ELISA Development
  161. Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain.
    Authors: Hirst SJ, Hallsworth MP, Peng Q
    Am. J. Respir. Crit. Care Med., 2002-04-15;165(8):1161-71.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  162. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
    Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
    Immunity, 2001-06-01;14(6):705-14.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA Development
  163. Chemoattractant factors in breast milk from allergic and nonallergic mothers.
    Authors: Bottcher MF, Jenmalm MC, Bjorksten B, Garofalo RP
    Pediatr. Res., 2000-05-01;47(5):592-7.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Development
  164. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment
    Authors: Mirella Georgouli, Cecilia Herraiz, Eva Crosas-Molist, Bruce Fanshawe, Oscar Maiques, Anna Perdrix et al.
    Cell
  165. Autophagy-based unconventional secretion of HMGB1 in glioblastoma promotes chemosensitivity to temozolomide through macrophage M1-like polarization
    Authors: Li Z, Fu WJ, Chen XQ et al.
    Journal of experimental & clinical cancer research : CR
  166. Expression of human papillomavirus type 16 E7 is sufficient to significantly increase expression of angiogenic factors but is not sufficient to induce endothelial cell migration
    Authors: Joanna Walker, Lucy Clare Smiley, David Ingram, Ann Roman
    Virology
  167. Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway
    Authors: X Sun, B Shi, H Zheng, L Min, J Yang, X Li, X Liao, W Huang, M Zhang, S Xu, Z Zhu, H Cui, X Liu
    Cell Death Dis, 2018-02-15;9(3):260.
  168. Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma
    Authors: Dan Huang, Yan Ding, Ming Zhou, Brian I. Rini, David Petillo, Chao-Nan Qian et al.
    Cancer Research
  169. Endothelial P2Y2 receptor regulates LPS-induced neutrophil transendothelial migration in vitro
    Authors: Filip Kukulski, Fethia Ben Ben Yebdri, Fariborz Bahrami, Michel Fausther, Alain Tremblay, Jean Sévigny
    Molecular Immunology
  170. Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization
    Authors: Jie Ji, Swapna Upadhyay, Xiaomiao Xiong, Maria Malmlöf, Thomas Sandström, Per Gerde et al.
    Particle and Fibre Toxicology
  171. PHF11 expression and cellular distribution is regulated by the Toll-Like Receptor 3 Ligand Polyinosinic:Polycytidylic Acid in HaCaT keratinocytes
    Authors: Pauline Muscat, Karessa Mercado, Kathryn Payne, Hardip Chahal, Graham Jones
    BMC Immunology
  172. Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production
    Authors: Ravi Holani, Anshu Babbar, Graham A. D. Blyth, Fernando Lopes, Humberto Jijon, Derek M. McKay et al.
    Gut Microbes
  173. Schwann cells promote the migration and invasion of colorectal cancer cells via the activated NF-kappa B/IL-8 axis in the tumor microenvironment
    Authors: Shuhai Chen, Mingyou Chen
    Frontiers in Oncology
  174. Human neutrophils depend on extrinsic factors produced by monocytes for their survival response to TLR4 stimulation
    Authors: Shuvasree SenGupta, Madhavi J Rane, Silvia M Uriarte, Cassandra Woolley, Thomas C Mitchell
    Innate Immunity
  175. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
    Authors: Vinit Kumar, Laxminarasimha Donthireddy, Douglas Marvel, Thomas Condamine, Fang Wang, Sergio Lavilla-Alonso et al.
    Cancer Cell
  176. Mitochondrial DNA has a pro-inflammatory role in AMD
    Authors: Bernard Dib, Haijiang Lin, Daniel E. Maidana, Bo Tian, John B. Miller, Peggy Bouzika et al.
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  177. Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study
    Authors: Michael Lichtenauer, Michael Mildner, Konrad Hoetzenecker, Matthias Zimmermann, Bruno Karl Podesser, Wolfgang Sipos et al.
    Basic Research in Cardiology
  178. IFNgamma induces JAK1/STAT1/p65 NFkappaB-dependent interleukin-8 expression in ovarian cancer cells, resulting in their increased migration
    Authors: S Padmanabha, B Gaire, Y Zou, MM Uddin, D DeLeon, I Vancurova
    The international journal of biochemistry & cell biology, 2021-10-06;141(0):106093.
  179. Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients
    Authors: Antonia Patsialou, Yarong Wang, Juan Lin, Kathleen Whitney, Sumanta Goswami, Paraic A Kenny et al.
    Breast Cancer Research
  180. N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM
    Authors: G Kaufman, D Skrtic
    Int J Mol Sci, 2020-10-03;21(19):.

FAQs

  1. Are mouse or rat CXCL8/IL-8 products offered?

    • Mouse and rat do not have a gene which encodes CXCL8/IL-8. In mouse, the functional homologs to human CXCL8/IL-8 are CXCL1/KC and CXCL2/MIP-2. In rat, the functional homolog to CXCL8/human IL-8 is CXCL3/CINC-2.

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Human IL-8/CXCL8 Antibody
By Anonymous on 08/13/2023
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Colon cancer tissue Species: Human

IF of CXCL8 was done using dilution of 1:2000 in 2.5% horse serum/PBS and incubated at 4 degree overnight, and AF488 conjugated secondary antibody was used for 1h at RT.

Human IL-8/CXCL8 Antibody
By Anonymous on 08/06/2021
Application: IHC Sample Tested: Brain tumor Species: Human

Yellow arrows on the picture indicate staining in tumor cells.

Human IL-8/CXCL8 Antibody
By Anonymous on 07/30/2021
Application: WB Sample Tested: macrophage Species: Human
Human IL-8/CXCL8 Antibody
By Anonymous on 03/16/2020
Application: Func Sample Tested: Whole Cells Species: Human
Functional Assay Human IL-8/CXCL8 Antibody MAB208
Human IL-8/CXCL8 Antibody
By Anonymous on 05/27/2019
Application: B/N Sample Tested: Breast cancer cells,Serum-free Cell Culture Media Species: Human
Human IL-8/CXCL8 Antibody
By Anonymous on 11/10/2018
Application: ELISA Sample Tested: Plasma Species: Human
Human IL-8/CXCL8 Antibody
By Zoia Levashova on 11/01/2018
Application: MSD assay Sample Tested: Vitreous humor Species: Cynomolgus Monkey and Porcine

After biotinylation, used as a capture reagent according to the manufacturer’s protocol (Meso Scale Diagnostics LLC).
A: Paired with SulfoTag-modified AF-208-NA as a detection antibody. Calibration curves with Recombinant Human IL-8 (208-IL-010/CF) is shown (dynamic range 1.6-25,000 pg/ml).
B: Paired with SulfoTag-modified MAB-535 to detect porcine IL-8. Calibration curves with Recombinant Porcine IL-8 (535-IN/CF) is shown (dynamic range 1.6-25,000 pg/ml).

Other Human IL-8/CXCL8 Antibody MAB208
Human IL-8/CXCL8 Antibody
By Prasanna Ekambaram on 05/11/2018
Application: B/N Sample Tested: Breast cancer cells Species: Human

We used this IL8 neutralizing antibody (600 ng/mL) as part of an antibody cocktail containing several other antibodies to neutralize IL8 present in the Conditioned Medium (CM) from BT549 Cells treated with Angiotensin II.
CM (+/- IL8 Neutralizing ab Cocktail) was used to further look at Endothelial (HUVEC) Cell migration using Incucyte Chemotaxis Assay.
Cancer Res; 78(5) March 1, 2018 (Fig 6F)

Block/Neutralize Human IL-8/CXCL8 Antibody MAB208
Human IL-8/CXCL8 Antibody
By Leslie Priddy on 04/03/2018
Application: ELISA Sample Tested: Serum Species: Human
Human IL-8/CXCL8 Antibody
By Michelle Chen on 04/26/2017
Application: B/N Sample Tested: Neutrophils Species: Human