Human LMTK2 Antibody

Catalog # Availability Size / Price Qty
MAB5147
MAB5147-SP
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Human LMTK2 Antibody Summary

Species Reactivity
Human
Specificity
Detects human LMTK2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human AATK is observed.
Source
Monoclonal Rat IgG2B Clone # 465222
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human LMTK2
Ala93-Tyr284
Accession # Q8IWU2
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human LMTK2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: LMTK2

LMTK2 (lemur tyrosine kinase 2), also known as KPI-2 (kinase/phosphatase inhibitor 2), cprk (cdk5-regulated kinase) or Brek (brain-enriched kinase), is a 210 kDa type I transmembrane ser/thr kinase that is a member of the lemur family of kinases with long (lemur-like) C-terminal cytoplasmic tails. It is expressed mainly in the brain and is enriched in perinatal neurons, but is also found in germ cells. Amino acids (aa) 93‑284 of human LMTK2 share 93% and 92% aa identity with mouse and rat LMTK2, respectively.

Long Name
Lemur Tyrosine Kinase 2, Serine/Threonine-protein Kinase LMTK2
Entrez Gene IDs
22853 (Human); 231876 (Mouse); 304286 (Rat)
Alternate Names
AATK2; AATYK2FLJ46659; Apoptosis-associated tyrosine kinase 2; Brain-enriched kinase; BREK; BREKCDK5/p35-regulated kinase; CPRK; EC 2.7.11; KIAA1079hBREK; kinase phosphatase inhibitor 2; Kinase/phosphatase/inhibitor 2; KPI-2; KPI2EC 2.7.11.1; lemur tyrosine kinase 2Serine/threonine-protein kinase KPI-2; LMR2; LMR2cyclin-dependent kinase 5/p35-regulated kinase; LMTK2; serine/threonine-protein kinase LMTK2

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