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Human/Mouse Active Caspase-3 Antibody

Catalog #: AF835
203 Citations 5 Reviews Datasheet / COA / SDS
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AF835
AF835-SP
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Caspase‑3 in Jurkat Human Cell Line.
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Citations (203)
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Reviews (5)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse Active Caspase-3 Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Distinguishes apoptotic cells from non-apoptotic cells in immunohistochemistry. Detects the p17 subunit of Caspase-3, but does not detect the precursor form in Western blot. We recommend R&D Systems Affinity Purified Anti-Caspase-3 (Catalog # AF-605-NA) or Monoclonal Anti-Cleaved-Caspase-3 (Catalog # MAB835) for Western blot applications.
Source
Polyclonal Rabbit IgG
Purification
Antigen Affinity-purified
Immunogen
KLH-coupled human Caspase-3 synthetic peptide
CRGTELDCGIETD
Accession # P42574
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Immunohistochemistry
1-15 µg/mL
See below
Immunocytochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunocytochemistry Caspase‑3 antibody in Jurkat Human Cell Line by Immunocytochemistry (ICC). View Larger

Caspase‑3 in Jurkat Human Cell Line. Caspase‑3 was detected in immersion fixed anti-FAS treated Jurkat human acute T cell leukemia cell line using 0.3 µg/mL Human/Mouse Active Caspase‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF835) for 3 hours at room temperature. Cells were stained (red) and counterstained (green). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Immunocytochemistry Caspase-3 antibody in Jurkat Human Cell Line by Immunocytochemistry (ICC). View Larger

Caspase‑3 in Jurkat Human Cell Line. Caspase-3 was detected in immersion fixed Jurkat human acute T cell leukemia cell line stimulated with staurosporin using Human/Mouse Active Caspase-3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF835) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rabbit IgG Secondary Antibody (yellow; Catalog # NL004) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Immunohistochemistry Caspase-3 antibody in Human Colon Cancer Tissue by Immunohistochemistry (IHC-P). View Larger

Caspase‑3 in Human Colon Cancer Tissue. Caspase-3 was detected in immersion fixed paraffin-embedded sections of human colon cancer tissue using Rabbit Anti-Human/Mouse Active Caspase-3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF835) at 1 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Caspase-3

Caspase-3 (Cysteine-aspartic acid protease 3/Casp3; also Yama, apopain and CPP32) is a 29 kDa heterodimer that belongs to the peptidase C14A family of enzymes. It is widely expressed, and considered to be the major executioner caspase in the apoptotic cascade. Human procaspase-3 is a 32 kDa, 277 amino acid (aa) protein and is normally an inactive homodimer. Following cell stress/activation, procaspase-3 undergoes proteolysis to generate an N-terminal 148 aa p17/17 kDa subunit (aa 29-175), plus a 102 aa C-terminal p12/12 kDa subunit. These subunits noncovalently heterodimerize, and associate with another p17/p12 heterodimer to form an active enzyme. There is one potential variant that shows an alternative start site nine aa upstream of the standard start site coupled with a 21 aa substitution for aa 162-277. Over aa 29-175, human and mouse caspase-3 share 87% aa identity.

Entrez Gene IDs
836 (Human); 12367 (Mouse)
Alternate Names
Apopain; apoptosis-related cysteine protease; CASP3; CASP-3; caspase 3, apoptosis-related cysteine peptidase; Caspase3; Caspase-3; CPP32; CPP-32; CPP32B; CPP32SREBP cleavage activity 1; Cysteine protease CPP32; EC 3.4.22; EC 3.4.22.56; LICE-1; PARP cleavage protease; procaspase3; Protein Yama; SCA-1; YAMA

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Citations for Human/Mouse Active Caspase-3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

203 Citations: Showing 1 - 10
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  1. Analysis of gene and protein expression in the endometrium for validation of an ex vivo model of the equine uterus using PCR, digital and visual histopathology
    Authors: Köhne, M;Diel, E;Packeiser, EM;Böttcher, D;Tönissen, A;Unruh, C;Goericke-Pesch, S;Ulrich, R;Sieme, H;
    Theriogenology
    Species: Eubacterium plexicaudatum
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  2. Early IGF-1 receptor inhibition in mice mimics preterm human brain disorders and reveals a therapeutic target
    Authors: Potenzieri, A;Uccella, S;Preiti, D;Pisoni, M;Rosati, S;Lavarello, C;Bartolucci, M;Debellis, D;Catalano, F;Petretto, A;Nobili, L;Fellin, T;Tucci, V;Ramenghi, LA;Savardi, A;Cancedda, L;
    Science advances
    Species: Murine polyomavirus strain A3
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  3. Mice Mutated in the Third Fibronectin Domain of L1 Show Enhanced Hippocampal Neuronal Cell Death, Astrogliosis and Alterations in Behavior
    Authors: Congiu, L;Granato, V;Jakovcevski, I;Kleene, R;Fernandes, L;Freitag, S;Kneussel, M;Schachner, M;Loers, G;
    Biomolecules
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  4. Human Bone Marrow-Derived Mesenchymal Stromal Cells Reduce the Severity of Experimental Necrotizing Enterocolitis in a Concentration-Dependent Manner
    Authors: L Provitera, A Tomaselli, G Raffaeli, S Crippa, C Arribas, I Amodeo, S Gulden, GS Amelio, V Cortesi, F Manzoni, G Cervellini, J Cerasani, C Menis, N Pesenti, M Tripodi, L Santi, M Maggioni, C Lonati, S Oldoni, F Algieri, F Garrido, ME Bernardo, F Mosca, G Cavallaro
    Cells, 2023-02-27;12(5):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression
    Authors: P Martino, R Sunkara, N Heitman, M Rangl, A Brown, N Saxena, L Grisanti, D Kohan, M Yanagisawa, M Rendl
    Nature Cell Biology, 2023-01-30;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  6. Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation
    Authors: D Piekna-Prz, D Na, J Zhang, C Baker, JM Ashton, PM White
    Frontiers in Cellular Neuroscience, 2023-01-06;16(0):1096872.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  7. p53/p21 pathway activation contributes to the ependymal fate decision downstream of GemC1
    Authors: G Ortiz-Álva, A Fortoul, A Srivastava, MX Moreau, B Bouloudi, C Mailhes-Ha, N Delgehyr, M Faucourt, M Bahin, C Blugeon, M Breau, V Géli, F Causeret, A Meunier, N Spassky
    Cell Reports, 2022-12-13;41(11):111810.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  8. Antitumor activity of photodynamic therapy with tetracationic derivative of synthetic bacteriochlorin in spheroid culture of liver and colon cancer cells
    Authors: SS Karshieva, EG Glinskaya, AA Dalina, EV Akhlyustin, EA Makarova, YD Khesuani, NS Chmelyuk, MA Abakumov, DA Khochenkov, VA Mironov, GA Meerovich, EA Kogan, EV Koudan
    Photodiagnosis and photodynamic therapy, 2022-11-15;0(0):103202.
    Species: Human
    Sample Types: Spheroids
    Applications: IHC
  9. Senescence plays a role in Myotonic Dystrophy type 1
    Authors: M García-Pug, A Saenz-Anto, G Gerenu, A Arrieta, R Fernandez-, M Zulaica, A Saenz, J Elizazu, G Nogales-Ga, SM Gadalla, MJ Araúzo-Bra, A Lopez de M, A Matheu
    JCI Insight, 2022-10-10;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  10. Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
    Authors: EG Vasquez, N Nasreddin, GN Valbuena, EJ Mulholland, HL Belnoue-Da, HR Eggington, RO Schenck, VM Wouters, P Wirapati, K Gilroy, TRM Lannagan, DJ Flanagan, AK Najumudeen, S Omwenga, AMB McCorry, A Easton, VH Koelzer, JE East, D Morton, L Trusolino, T Maughan, AD Campbell, MB Loughrey, PD Dunne, P Tsantoulis, DJ Huels, S Tejpar, OJ Sansom, SJ Leedham
    Cell Stem Cell, 2022-08-04;29(8):1213-1228.e8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  11. Smooth muscle cell specific NEMO deficiency inhibits atherosclerosis in ApoE-/- mice
    Authors: T Imai, TM Van, M Pasparakis, A Polykratis
    Scientific Reports, 2022-07-22;12(1):12538.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  12. RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer
    Authors: AE Hall, SÖ Pohl, P Cammareri, S Aitken, NT Younger, M Raponi, CV Billard, AB Carrancio, A Bastem, P Freile, F Haward, IR Adams, JF Caceres, P Preyzner, A von Kriegs, MG Dunlop, FV Din, KB Myant
    Nature Communications, 2022-05-19;13(1):2791.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  13. Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity
    Authors: RJ Krawetz, YE Wu, KL Bertram, A Shonak, AO Masson, G Ren, C Leonard, M Kapoor, JR Matyas, PT Salo
    Cell Death & Disease, 2022-05-18;13(5):470.
    Species: Human, Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  14. Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis
    Authors: R Belgacemi, S Danopoulos, G Deutsch, I Glass, V Dormoy, S Bellusci, D Al Alam
    International Journal of Molecular Sciences, 2022-05-09;23(9):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  15. Immunohistochemical Expression of Oxidative Stress and Apoptosis Markers in Archived Liver Specimens from Dogs with Chronic Hepatitis
    Authors: P Yamkate, JA Lidbury, JM Steiner, JS Suchodolsk, PR Giaretta
    Journal of comparative pathology, 2022-04-01;193(0):25-36.
    Species: Canine
    Sample Types: Whole Tissue
    Applications: IHC
  16. Ruscogenins Improve CD-Like Enteritis by Inhibiting Apoptosis of Intestinal Epithelial Cells and Activating Nrf2/NQO1 Pathway
    Authors: H Wen, X Zhang, Q Li, J Huang, G Liu, J Zhao, Y Liu, L Shen, Y Li, K Yang, L Zuo, J Li, J Nian, P Xiang, H Zhao, L Yu, M Liu, Z Geng, X Song
    Oxidative Medicine and Cellular Longevity, 2022-03-10;2022(0):4877275.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC/IF
  17. Angiogenesis depends upon EPHB4-mediated export of collagen IV from vascular endothelial cells
    Authors: D Chen, ED Hughes, TL Saunders, J Wu, MN Hernández, T Makinen, PD King
    JCI Insight, 2022-02-22;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  18. Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis
    Authors: C Lee, J Kim, J Han, D Oh, M Kim, H Jeong, TJ Kim, SW Kim, JN Kim, YS Seo, A Suzuki, JH Kim, Y Jung
    Nature Communications, 2022-01-31;13(1):578.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  19. T cell apoptosis characterizes severe Covid-19 disease
    Authors: S André, M Picard, R Cezar, F Roux-Dalva, A Alleaume-B, C Soundaramo, AS Cruz, A Mendes-Fri, C Gotti, M Leclercq, A Nicolas, A Tauzin, A Carvalho, C Capela, J Pedrosa, AG Castro, L Kundura, P Loubet, A Sotto, L Muller, JY Lefrant, C Roger, PG Claret, S Duvnjak, TA Tran, G Racine, O Zghidi-Abo, P Nioche, R Silvestre, A Droit, F Mammano, P Corbeau, J Estaquier
    Cell Death and Differentiation, 2022-01-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  20. Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration
    Authors: P Flora, MY Li, PM Galbo, M Astorkia, D Zheng, E Ezhkova
    PloS Genetics, 2021-12-14;17(12):e1009948.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  21. BET Proteins Regulate Expression of Osr1 in Early Kidney Development
    Authors: J Schreiber, N Liaukouska, L Fuhrmann, AT Hauser, M Jung, TB Huber, N Wanner
    Biomedicines, 2021-12-10;9(12):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  22. Peptide backbone modifications of amyloid beta (1-40) impact fibrillation behavior and neuronal toxicity
    Authors: B Schwarze, A Korn, C Höfling, U Zeitschel, M Krueger, S Ro beta ner, D Huster
    Scientific Reports, 2021-12-09;11(1):23767.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  23. Regenerative Polarity of the Fin Ray in Zebrafish Caudal Fin and Related Tissue Formation on the Cut Surface
    Authors: W Nakajima, S Nakanishi, R Hosoya, T Uemoto, S Ohgo, N Wada
    Journal of developmental biology, 2021-11-19;9(4):.
    Species: Zebrafish
    Sample Types: Whole Tissue
    Applications: IHC
  24. Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma
    Authors: M Dottermusc, P Sumis?awsk, J Krevet, M Middelkamp, H Vo beta, B Siebels, H Bartsch, K Sotlar, P Meyer, S Frank, A Korshunov, M Glatzel, U Schüller, JE Neumann
    Oncogenesis, 2021-11-16;10(11):78.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  25. Recapitulating cholangiopathy-associated necroptotic cell death in vitro using human cholangiocyte organoids
    Authors: S Shi, MMA Verstegen, HP Roest, AI Ardisasmit, W Cao, FJM Roos, PE de Ruiter, M Niemeijer, Q Pan, JNM IJzermans, LJW van der La
    Cellular and Molecular Gastroenterology and Hepatology, 2021-10-23;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IF
  26. Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion
    Authors: C Junqueira, R Dariolli, J Haydak, S Kang, T Hannah, RJ Wiener, S DeFronzo, R Tejero, GL Gusella, A Ramakrishn, R Alves Dias, A Wojcinski, S Kesari, L Shen, EA Sobie, JP Rodrigues, EU Azeloglu, H Zou, RH Friedel
    Nature Communications, 2021-10-14;12(1):6019.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  27. USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma
    Authors: EJ Ruiz, A Pinto-Fern, AP Turnbull, L Lan, TM Charlton, HC Scott, A Damianou, G Vere, EM Riising, C Da Costa, WW Krajewski, D Guerin, JD Kearns, S Ioannidis, M Katz, C McKinnon, J O'Connell, N Moncaut, I Rosewell, E Nye, N Jones, C Heride, M Gersch, M Wu, CJ Dinsmore, TR Hammonds, S Kim, D Komander, S Urbe, MJ Clague, BM Kessler, A Behrens
    Elife, 2021-10-12;10(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  28. Sprague Dawley Rats Gaining Weight on a High Energy Diet Exhibit Damage to Taste Tissue Even after Return to a Healthy Diet
    Authors: F Harnischfe, F O'Connell, M Weiss, B Axelrod, A Hajnal, K Czaja, PM Di Lorenzo, R Dando
    Nutrients, 2021-08-31;13(9):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  29. A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis
    Authors: D Pradella, G Deflorian, A Pezzotta, A Di Matteo, E Belloni, D Campolungo, A Paradisi, M Bugatti, W Vermi, M Campioni, A Chiapparin, L Scietti, F Forneris, C Giampietro, N Volf, M Rehman, S Zacchigna, MP Paronetto, A Pistocchi, A Eichmann, P Mehlen, C Ghigna
    Nature Communications, 2021-08-11;12(1):4872.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  30. Umbilical cord blood therapy modulates neonatal hypoxic ischemic brain injury in both females and males
    Authors: TR Penny, Y Pham, AE Sutherland, J Lee, G Jenkin, MC Fahey, SL Miller, CA McDonald
    Scientific Reports, 2021-08-04;11(1):15788.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  31. Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression
    Authors: HM Schmitt, RL Fehrman, ME Maes, H Yang, LW Guo, CL Schlamp, HR Pelzel, RW Nickells
    Investigative Ophthalmology & Visual Science, 2021-08-02;62(10):14.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  32. Meiotic Silencing in Pigs: A Case Study in a Translocated Azoospermic Boar
    Authors: N Mary, A Calgaro, H Barasc, N Bonnet, S Ferchaud, I Raymond-Le, A Ducos, A Pinton
    Genes, 2021-07-27;12(8):.
    Species: Porcine
    Sample Types: Whole Tissue
    Applications: IHC
  33. Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells
    Authors: A Soni, D Klütsch, X Hu, J Houtman, N Rund, A McCloskey, J Mertens, ST Schafer, H Amin, T Toda
    Cells, 2021-07-26;10(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  34. Curcumin Attenuates Environment-Derived Osteoarthritis by Sox9/NF-kB Signaling Axis
    Authors: C Buhrmann, A Brockmuell, AL Mueller, P Shayan, M Shakibaei
    International Journal of Molecular Sciences, 2021-07-16;22(14):.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Immunoprecipitation, Western Blot
  35. Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis
    Authors: ML Wegscheid, C Anastasaki, KA Hartigan, OM Cobb, JB Papke, JN Traber, SM Morris, DH Gutmann
    Cell Reports, 2021-07-06;36(1):109315.
    Species: Human
    Sample Types: Organoids
    Applications: IHC
  36. Evidence That Tumor Microenvironment Initiates Epithelial-To-Mesenchymal Transition and Calebin A can Suppress it in Colorectal Cancer Cells
    Authors: C Buhrmann, A Brockmuell, C Harsha, AB Kunnumakka, P Kubatka, BB Aggarwal, M Shakibaei
    Frontiers in Pharmacology, 2021-07-02;12(0):699842.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  37. MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling
    Authors: H Nakashima, K Tsujimura, K Irie, T Imamura, CA Trujillo, M Ishizu, M Uesaka, M Pan, H Noguchi, K Okada, K Aoyagi, T Andoh-Noda, H Okano, AR Muotri, K Nakashima
    Cell Reports, 2021-05-18;35(7):109124.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: ICC
  38. G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic
    Authors: T Ingwersen, C Linnenberg, E D'Acunto, S Temori, I Paolucci, D Wasilewski, B Mohammadi, J Kirchmair, RC Glen, E Miranda, M Glatzel, G Galliciott
    Scientific Reports, 2021-04-22;11(1):8766.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  39. Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality
    Authors: MT Dang, MV Gonzalez, KS Gaonkar, KS Rathi, P Young, S Arif, L Zhai, Z Alam, S Devalaraja, TKJ To, IW Folkert, P Raman, JL Rokita, D Martinez, JN Taroni, JA Shapiro, CS Greene, C Savonen, F Mafra, H Hakonarson, T Curran, M Haldar
    Cell Reports, 2021-03-30;34(13):108917.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  40. Chronic exposure to IL-6 induces a desensitized phenotype of the microglia
    Authors: M Recasens, B Almolda, J Pérez-Clau, IL Campbell, B González, B Castellano
    Journal of Neuroinflammation, 2021-01-22;18(1):31.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  41. Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy
    Authors: M Tajan, M Hennequart, EC Cheung, F Zani, AK Hock, N Legrave, ODK Maddocks, RA Ridgway, D Athineos, A Suárez-Bon, RL Ludwig, L Novellasde, N Angelis, VSW Li, G Vlachogian, N Valeri, N Mainolfi, V Suri, A Friedman, M Manfredi, K Blyth, OJ Sansom, KH Vousden
    Nature Communications, 2021-01-14;12(1):366.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  42. Individual-oocyte transcriptomic analysis shows that genotoxic chemotherapy depletes human primordial follicle reserve�in vivo by triggering proapoptotic pathways without growth activation
    Authors: S Titus, KJ Szymanska, B Musul, V Turan, E Taylan, R Garcia-Mil, S Mehta, K Oktay
    Scientific Reports, 2021-01-11;11(1):407.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  43. Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice
    Authors: KM Schukken, Y Zhu, PL Bakker, MH Koster, L Harkema, SA Youssef, A de Bruin, F Foijer
    Scientific Reports, 2021-01-08;11(1):68.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  44. ABL001, a Bispecific Antibody Targeting VEGF and DLL4, with Chemotherapy, Synergistically Inhibits Tumor Progression in Xenograft Models
    Authors: DH Yeom, YS Lee, I Ryu, S Lee, B Sung, HB Lee, D Kim, JH Ahn, E Ha, YS Choi, SH Lee, WK You
    International Journal of Molecular Sciences, 2020-12-29;22(1):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  45. Pantoprazole impairs fracture healing in aged mice
    Authors: MM Menger, P Bremer, C Scheuer, MF Rollmann, BJ Braun, SC Herath, M Orth, T Später, T Pohlemann, MD Menger, T Histing
    Scientific Reports, 2020-12-23;10(1):22376.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  46. Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons
    Authors: Y Arioka, E Shishido, I Kushima, T Suzuki, R Saito, A Aiba, D Mori, N Ozaki
    EBioMedicine, 2020-12-17;63(0):103138.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  47. Naringenin exerts anticancer effects by inducing tumor cell death and inhibiting angiogenesis in malignant melanoma
    Authors: J Choi, DH Lee, H Jang, SY Park, JW Seol
    International Journal of Medical Sciences, 2020-10-18;17(18):3049-3057.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  48. Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon
    Authors: B Di Marco, EE Crouch, B Shah, C Duman, MF Paredes, C Ruiz de Al, EJ Huang, J Alfonso
    Cell Rep, 2020-10-13;33(2):108256.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  49. Effects of the Delta Opioid Receptor Agonist DADLE in a Novel Hypoxia-Reoxygenation Model on Human and Rat-Engineered Heart Tissue: A Pilot Study
    Authors: S Funcke, TR Werner, M Hein, BM Ulmer, A Hansen, T Eschenhage, MN Hirt
    Biomolecules, 2020-09-11;10(9):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  50. Inhibition of DDR1 enhances in vivo chemosensitivity in KRAS-mutant lung adenocarcinoma
    Authors: MJ Nokin, E Darbo, C Travert, B Drogat, A Lacouture, S San José, N Cabrera, B Turcq, V Prouzet-Ma, M Falcone, A Villanueva, H Wang, M Herfs, M Mosteiro, PA Jänne, JL Pujol, A Maraver, M Barbacid, E Nadal, D Santamaría, C Ambrogio
    JCI Insight, 2020-08-06;5(15):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  51. Characterization of a new small-molecule inhibitor of HDAC6 in glioblastoma
    Authors: J Auzmendi-I, A Saenz-Anto, I Mikelez-Al, E Carrasco-G, M Tellaetxe-, CH Lawrie, N Sampron, AL Cortajaren, A Matheu
    Cell Death Dis, 2020-06-02;11(6):417.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  52. Targeting Actomyosin Contractility Suppresses Malignant Phenotypes of Acute Myeloid Leukemia Cells
    Authors: F Chang, SJ Kong, L Wang, BK Choi, H Lee, C Kim, JM Kim, K Park
    Int J Mol Sci, 2020-05-14;21(10):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  53. Erbb4 Is Required for Cerebellar Developmentand Malignant Phenotype of Medulloblastoma
    Authors: J Aldaregia, P Errarte, A Olazagoiti, M Gimeno, JJ Uriz, TR Gershon, I Garcia, A Matheu
    Cancers (Basel), 2020-04-17;12(4):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  54. Ex Vivo MRI Analytical Methods and Brain Pathology in Preterm Lambs Treated with Postnatal Dexamethasone �
    Authors: NJ Yates, KW Feindel, A Mehnert, R Beare, S Quick, D Blache, JJ Pillow, RW Hunt
    Brain Sci, 2020-04-03;10(4):.
    Species: Lamb
    Sample Types: Whole Tissue
    Applications: IHC
  55. Hypoxia-induced complement dysregulation is associated with microvascular impairments in mouse tracheal transplants
    Authors: MA Khan, T Shamma, S Kazmi, A Altuhami, HA Ahmed, AM Assiri, DC Broering
    J Transl Med, 2020-03-31;18(1):147.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  56. Embryonic Barcoding of Equipotent Mammary Progenitors Functionally Identifies Breast Cancer Drivers
    Authors: Z Ying, S Beronja
    Cell Stem Cell, 2020-02-13;0(0):.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  57. SOX9 promotes tumor progression through the axis BMI1-p21CIP
    Authors: P Aldaz, M Otaegi-Uga, A Saenz-Anto, M Garcia-Pug, M Moreno-Val, JM Flores, D Gerovska, MJ Arauzo-Bra, N Samprón, A Matheu, E Carrasco-G
    Sci Rep, 2020-01-15;10(1):357.
    Species: Human
    Sample Types: Whole Cells
    Applications: IF
  58. Neurovascular effects of umbilical cord blood-derived stem cells in growth-restricted newborn lambs : UCBCs for perinatal brain injury
    Authors: A Malhotra, M Castillo-M, BJ Allison, AE Sutherland, I Nitsos, Y Pham, CA McDonald, MC Fahey, GR Polglase, G Jenkin, SL Miller
    Stem Cell Res Ther, 2020-01-08;11(1):17.
  59. Expression of apoptotic and proliferation factors in gastric mucosa of patients with systemic sclerosis correlates with form of the disease
    Authors: K Boric, S Mardesic, D Martinovic, M Radic, I Tadin Hadj, K Vukojevic, I Kosovic, I Solic, S Zekic Toma, M Saraga-Bab
    Sci Rep, 2019-12-05;9(1):18461.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  60. NF-kappaB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells
    Authors: LG Jones, A Vaida, LM Thompson, FI Ikuomola, JH Caamaño, MD Burkitt, F Miyajima, JM Williams, BJ Campbell, DM Pritchard, CA Duckworth
    Cell Death Dis, 2019-11-26;10(12):896.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  61. Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs
    Authors: E Grall, V Gourain, A Naïr, E Martin, MC Birling, JN Freund, I Duluc
    Cell Death Dis, 2019-10-24;10(11):812.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  62. Kidins220/ARMS controls astrocyte calcium signaling and neuron-astrocyte communication
    Authors: F Jaudon, M Chiacchiar, M Albini, S Ferroni, F Benfenati, F Cesca
    Cell Death Differ., 2019-10-17;27(5):1505-1519.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: ICC
  63. Aberrant DNA Polymerase Beta Enhances H. pylori Infection Induced Genomic Instability and Gastric Carcinogenesis in Mice
    Authors: S Zhao, M Thakur, AW Klattenhof, D Kidane
    Cancers (Basel), 2019-06-18;11(6):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  64. TBC1D24 regulates axonal outgrowth and membrane trafficking at the growth cone in rodent and human neurons
    Authors: D Aprile, F Fruscione, S Baldassari, M Fadda, D Ferrante, A Falace, E Buhler, J Sartorelli, A Represa, P Baldelli, F Benfenati, F Zara, A Fassio
    Cell Death Differ., 2019-03-11;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  65. SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating ?-Catenin Nuclear Localization
    Authors: P Antas, L Novellasde, A Kucharska, I Massie, J Carvalho, D Oukrif, E Nye, M Novelli, VSW Li
    Cell Rep, 2019-02-26;26(9):2266-2273.e4.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  66. Aging differentially modulates the Wnt pro-survival signalling pathways in vascular smooth muscle cells
    Authors: BA Brown, GM Connolly, CEJ Mill, H Williams, GD Angelini, JL Johnson, SJ George
    Aging Cell, 2018-12-12;0(0):e12844.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  67. Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells
    Authors: O Bover, T Justo, PNG Pereira, J Facucho-Ol, JM Inácio, JS Ramalho, IJ Domian, JA Belo
    PLoS ONE, 2018-10-03;13(10):e0205108.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  68. Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation
    Authors: RK Zwick, MC Rudolph, BA Shook, B Holtrup, E Roth, V Lei, A Van Keymeu, V Seewaldt, S Kwei, J Wysolmersk, MS Rodeheffer, V Horsley
    Nat Commun, 2018-09-04;9(1):3592.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  69. BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer
    Authors: M Ouarné, C Bouvard, G Boneva, C Mallet, J Ribeiro, A Desroches-, E Soleilhac, E Tillet, O Peyruchaud, S Bailly
    J. Exp. Clin. Cancer Res., 2018-08-30;37(1):209.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  70. An Adult Zebrafish Model Reveals that Mucormycosis Induces Apoptosis of Infected Macrophages
    Authors: A López-Muño, FE Nicolás, D García-Mor, AB Pérez-Oliv, MI Navarro-Me, MA Hernández-, A Herrera-Es, S Torres-Mar, RM Ruiz-Vázqu, V Garre, V Mulero
    Sci Rep, 2018-08-24;8(1):12802.
    Species: Zebrafish
    Sample Types: Whole Tissue
    Applications: IHC-P
  71. The protective effects of total paeony glycoside on ischemia/reperfusion injury in H9C2 cells via inhibition of the PI3K/Akt signaling pathway
    Authors: P Shen, J Chen, M Pan
    Mol Med Rep, 2018-07-30;18(3):3332-3340.
    Species: Rat
    Sample Types: Cell Lysates
    Applications: Western Blot
  72. Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling
    Authors: M Baek, M Kim, JS Lim, LD Morales, J Hernandez, S Mummidi, S Williams-B, IS Jang, AT Tsin, DJ Kim
    Cell Death Dis, 2018-06-28;9(7):730.
    Species: Human
    Sample Types: Whole Cells
  73. Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction
    Authors: ML Piacentino, ME Bronner
    PLoS Biol., 2018-06-27;16(6):e2004425.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: IHC-P
  74. PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification
    Authors: I Cohen, D Zhao, C Bar, VJ Valdes, KL Dauber-Dec, MB Nguyen, M Nakayama, M Rendl, WA Bickmore, H Koseki, D Zheng, E Ezhkova
    Cell Stem Cell, 2018-05-03;22(5):726-739.e7.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  75. Shared effects of DISC1 disruption and elevated WNT signaling in human cerebral organoids
    Authors: P Srikanth, VN Lagomarsin, CR Muratore, SC Ryu, A He, WM Taylor, C Zhou, M Arellano, TL Young-Pear
    Transl Psychiatry, 2018-04-12;8(1):77.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  76. Synapsin I and Synapsin II regulate neurogenesis in the dentate gyrus of adult mice
    Authors: R Barbieri, A Contestabi, MG Ciardo, N Forte, A Marte, P Baldelli, F Benfenati, F Onofri
    Oncotarget, 2018-04-10;9(27):18760-18774.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  77. The kallikrein-Kinin system modulates the progression of colorectal liver metastases in a mouse model
    Authors: PLN da Costa, D Wynne, T Fifis, L Nguyen, M Perini, C Christophi
    BMC Cancer, 2018-04-04;18(1):382.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  78. Tracking cellular and molecular changes in a species-specific manner during experimental tumor progression in vivo
    Authors: E Indersie, KB Hooks, C Capdeviell, M Fabre, N Dugot-Sena, A Desplat, S Lepreux, A Merched, CF Grosset, M Hagedorn
    Oncotarget, 2018-03-01;9(22):16149-16162.
    Species: Human
    Sample Types: Complex Sample Type
    Applications: IHC
  79. A motif within the armadillo repeat of Parkinson's-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway
    Authors: N Antoniou, D Vlachakis, A Memou, E Leandrou, PE Valkimadi, K Melachroin, DB Re, S Przedborsk, WT Dauer, L Stefanis, HJ Rideout
    Sci Rep, 2018-02-22;8(1):3455.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  80. Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres
    Authors: JM Povedano, P Martinez, R Serrano, Á Tejera, G Gómez-Lópe, M Bobadilla, JM Flores, F Bosch, MA Blasco
    Elife, 2018-01-30;7(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  81. Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells
    Authors: N Dreyer-And, AS Almeida, P Jensen, M Kamand, J Okarmus, T Rosenberg, SD Friis, A Martínez S, M Blaabjerg, BW Kristensen, T Skrydstrup, JB Gramsberge, HLA Vieira, M Meyer
    PLoS ONE, 2018-01-16;13(1):e0191207.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  82. KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS
    Authors: C Ambrogio, J Köhler, ZW Zhou, H Wang, R Paranal, J Li, M Capelletti, C Caffarra, S Li, Q Lv, S Gondi, JC Hunter, J Lu, R Chiarle, D Santamaría, KD Westover, PA Jänne
    Cell, 2018-01-11;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  83. Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression
    Authors: CA Lyon, H Williams, R Bianco, SJ Simmonds, BA Brown, KS Wadey, FCT Smith, JL Johnson, SJ George
    Sci Rep, 2017-12-11;7(1):17342.
    Species: Human, Mouse
    Sample Types: Whole Tissue
    Applications: ICC, IHC
  84. Caspase-3/-7-Specific Metabolic Precursor for Bioorthogonal Tracking of Tumor Apoptosis
    Authors: MK Shim, HY Yoon, S Lee, MK Jo, J Park, JH Kim, SY Jeong, IC Kwon, K Kim
    Sci Rep, 2017-11-30;7(1):16635.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  85. The Process of Engraftment of Myogenic Cells in Skeletal Muscles of Primates: Understanding Clinical Observations and Setting Directions in Cell Transplantation Research
    Authors: D Skuk, JP Tremblay
    Cell Transplant, 2017-11-01;26(11):1763-1779.
    Species: Primate
    Sample Types: Whole Tissue
    Applications: IHC
  86. Oxidative damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail
    Authors: M Dezest, M Le Bechec, L Chavatte, V Desauziers, B Chaput, JL Grolleau, P Descargues, C Nizard, S Schnebert, S Lacombe, AL Bulteau
    Sci Rep, 2017-09-06;7(1):10707.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC, IHC-P
  87. Glycogen synthase kinase-3 inhibition sensitizes human induced pluripotent stem cells to thiol-containing antioxidants induced apoptosis
    Authors: C Tu, R Xu, M Koleti, J Zoldan
    Stem Cell Res, 2017-07-22;23(0):182-187.
    Species: Human
    Sample Types: Whole Cells
    Applications: Functional Assay
  88. New tumor suppressor microRNAs target glypican-3 in human liver cancer
    Authors: F Cartier, E Indersie, S Lesjean, J Charpentie, KB Hooks, A Ghousein, A Desplat, N Dugot-Sena, V Trézéguet, F Sagliocco, M Hagedorn, CF Grosset
    Oncotarget, 2017-06-20;0(0):.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: IHC
  89. Loss of the Wnt receptor Frizzled7 in the gastric epithelium is deleterious and triggers rapid repopulation in vivo
    Authors: DJ Flanagan, N Barker, C Nowell, H Clevers, M Ernst, TJ Phesse, E Vincan
    Dis Model Mech, 2017-06-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  90. VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis
    Authors: JY Jang, SY Choi, I Park, DY Park, K Choe, P Kim, YK Kim, BJ Lee, M Hirashima, Y Kubota, JW Park, SY Cheng, A Nagy, YJ Park, K Alitalo, M Shong, GY Koh
    EMBO Mol Med, 2017-06-01;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  91. A role for core planar polarity proteins in cell contact-mediated orientation of planar cell division across the mammalian embryonic skin
    Authors: F Oozeer, LL Yates, C Dean, CJ Formstone
    Sci Rep, 2017-05-12;7(1):1880.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  92. Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
    Authors: Lynne A Murray, Rebecca Dunmore, Ana Camelo, Carla A Da Silva, Malin J Gustavsso, David M Habiel, Tillie L Hackett, Cory M Hogaboam, Matthew A Sleeman, Darryl A Knight
    Respiratory Research, 2017-05-03;0(0):1465-993X.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  93. Constitutive WNT/CTNNB1 activation triggers spermatogonial stem cell proliferation and germ cell depletion
    Authors: AA Chassot, M Le Rolle, M Jourden, MM Taketo, NB Ghyselinck, MC Chaboissie
    Dev. Biol., 2017-04-26;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  94. The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries
    Authors: S Grasso, J Chapelle, V Salemme, S Aramu, I Russo, N Vitale, L Verdun di, K Dallaglio, I Castellano, A Amici, G Centonze, N Sharma, S Lunardi, S Cabodi, F Cavallo, A Lamolinara, L Stramucci, E Moiso, P Provero, A Albini, A Sapino, J Staaf, PP Di Fiore, G Bertalot, S Pece, D Tosoni, S Confalonie, M Iezzi, P Di Stefano, E Turco, P Defilippi
    Nat Commun, 2017-03-16;8(0):14797.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  95. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth
    Authors: JC Klein, K Moses, G Zelinskyy, S Sody, J Buer, S Lang, I Helfrich, U Dittmer, CJ Kirschning, S Brandau
    Nat Commun, 2017-03-16;8(0):14600.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  96. Low Dose Radiation Causes Skin Cancer In Mice And Has A Differential Effect on Distinct Epidermal Stem Cells
    Authors: T Revenco, G Lapouge, V Moers, S Broh‚e, PA Sotiropoul
    Stem Cells, 2017-02-01;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  97. Combined effects of atorvastatin and aspirin on growth and apoptosis in human prostate cancer cells
    Authors: Y He, H Huang, C Farischon, D Li, Z Du, K Zhang, X Zheng, S Goodin
    Oncol. Rep, 2017-01-04;37(2):953-960.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  98. Bifidobacterium breve reduces apoptotic epithelial cell shedding in an exopolysaccharide and MyD88-dependent manner
    Authors: KR Hughes, LC Harnisch, C Alcon-Gine, S Mitra, CJ Wright, J Ketskemety, D van Sinder, AJ Watson, LJ Hall
    Open Biol, 2017-01-01;7(1):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  99. Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo
    Redox Biol, 2016-12-18;11(0):219-230.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  100. cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool
    Cell Rep, 2016-12-06;17(10):2648-2659.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  101. Activation of FADD-Dependent Neuronal Death Pathways as a Predictor of Pathogenicity for LRRK2 Mutations
    PLoS ONE, 2016-11-10;11(11):e0166053.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  102. Proliferation, differentiation and migration of SCA1(-)/CD31(-) cardiac side population cells in vitro and in vivo
    Authors: Simon X Liang
    Int. J. Cardiol., 2016-11-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  103. Axonal Cleaved Caspase-3 Regulates Axon Targeting and Morphogenesis in the Developing Auditory Brainstem
    Authors: Karina S Cramer
    Front Neural Circuits, 2016-10-24;10(0):84.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: IHC
  104. CDK7 and miR-210 Co-regulate Cell-Cycle Progression of Neural Progenitors in the Developing Neocortex
    Stem Cell Reports, 2016-07-12;7(1):69-79.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  105. Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary
    Authors: M-C De Cian
    Oncogene, 2016-06-06;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  106. Defining the cellular lineage hierarchy in the interfollicular epidermis of adult skin
    Nat. Cell Biol., 2016-05-16;18(6):619-31.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  107. Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice
    J Neurosci, 2016-04-27;36(17):4758-70.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  108. Brinp1 (-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density
    Authors: SR Berkowicz, TJ Featherby, Z Qu, A Giousoh, NA Borg, JI Heng, JC Whisstock, PI Bird
    Mol Autism, 2016-03-31;7(0):22.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  109. Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue.
    Authors: Jacob F, Yonis A, Cuello F, Luther P, Schulze T, Eder A, Streichert T, Mannhardt I, Hirt M, Schaaf S, Stenzig J, Force T, Eschenhagen T, Hansen A
    PLoS ONE, 2016-02-03;11(2):e0145937.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P
  110. Cord blood mononuclear cells prevent neuronal apoptosis in response to perinatal asphyxia in the newborn lamb
    Authors: JD Aridas, CA McDonald, MC Paton, T Yawno, AE Sutherland, I Nitsos, Y Pham, M Ditchfield, MC Fahey, F Wong, A Malhotra, M Castillo-M, K Bhakoo, EM Wallace, G Jenkin, SL Miller
    J. Physiol. (Lond.), 2015-12-14;594(5):1421-35.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  111. Apoptosis-Related Factors in the Luteal Phase of the Domestic Cat and Their Involvement in the Persistence of Corpora Lutea in Lynx.
    Authors: Amelkina O, Zschockelt L, Painer J, Serra R, Villaespesa F, Braun B, Jewgenow K
    PLoS ONE, 2015-11-24;10(11):e0143414.
    Species: Feline
    Sample Types: Whole Tissue
    Applications: IHC-P
  112. Attenuation of Cerebral Ischemic Injury in Smad1 Deficient Mice.
    Authors: Wong J, Chen L, Huang Y, Sehba F, Friedel R, Zou H
    PLoS ONE, 2015-08-28;10(8):e0136967.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  113. An essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress.
    Authors: Quereda V, Porlan E, Canamero M, Dubus P, Malumbres M
    Cell Death Differ, 2015-08-21;23(3):430-41.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  114. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice.
    Authors: Douglas T, Champagne C, Morizot A, Lapointe J, Saleh M
    J Immunol, 2015-07-27;195(5):2365-73.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  115. BMP9 and BMP10 are necessary for proper closure of the ductus arteriosus.
    Authors: Levet S, Ouarne M, Ciais D, Coutton C, Subileau M, Mallet C, Ricard N, Bidart M, Debillon T, Faravelli F, Rooryck C, Feige J, Tillet E, Bailly S
    Proc Natl Acad Sci U S A, 2015-06-08;112(25):E3207-15.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  116. Exacerbated experimental colitis in TNFAIP8-deficient mice.
    Authors: Sun H, Lou Y, Porturas T, Morrissey S, Luo G, Qi J, Ruan Q, Shi S, Chen Y
    J Immunol, 2015-05-06;194(12):5736-42.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  117. Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer.
    Authors: Brindle N, Joyce J, Rostker F, Lawlor E, Swigart-Brown L, Evan G, Hanahan D, Shchors K
    PLoS ONE, 2015-04-30;10(4):e0120348.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  118. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs.
    Authors: Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M
    J Immunol, 2015-04-24;194(11):5529-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  119. Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.
    Authors: Sesen J, Dahan P, Scotland S, Saland E, Dang V, Lemarie A, Tyler B, Brem H, Toulas C, Cohen-Jonathan Moyal E, Sarry J, Skuli N
    PLoS ONE, 2015-04-13;10(4):e0123721.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  120. Hepatocyte-specific deletion of ARNT (aryl hydrocarbon Receptor Nuclear Translocator) results in altered fibrotic gene expression in the thioacetamide model of liver injury.
    Authors: Scott C, Cha K, Rao R, Liddle C, George J, Gunton J
    PLoS ONE, 2015-03-26;10(3):e0121650.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  121. TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus.
    Authors: Matsuda T, Murao N, Katano Y, Juliandi B, Kohyama J, Akira S, Kawai T, Nakashima K
    Nat Commun, 2015-03-09;6(0):6514.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  122. Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris.
    Authors: Luyet C, Schulze K, Sayar B, Howald D, Muller E, Galichet A
    PLoS ONE, 2015-03-06;10(3):e0119809.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  123. Interactions of highly and low virulent Flavobacterium columnare isolates with gill tissue in carp and rainbow trout.
    Authors: Declercq, Annelies, Chiers, Koen, Van den Broeck, Wim, Dewulf, Jeroen, Eeckhaut, Venessa, Cornelissen, Maria, Bossier, Peter, Haesebrouck, Freddy, Decostere, Annemie
    Vet Res, 2015-03-06;46(0):25.
    Species: Fish - Cyprinus carpio (Carp), Fish - Oncorhynchus mykiss (Rainbow Trout)
    Sample Types: Whole Tissue
    Applications: IHC-P
  124. Alpha-enolase is upregulated on the cell surface and responds to plasminogen activation in mice expressing a 133p53alpha mimic.
    Authors: Sawhney S, Hood K, Shaw A, Braithwaite A, Stubbs R, Hung N, Royds J, Slatter T
    PLoS ONE, 2015-02-02;10(2):e0116270.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  125. Interfering with stem cell-specific gatekeeper functions controls tumour initiation and malignant progression of skin tumours.
    Authors: Petersson, Monika, Reuter, Karen, Brylka, Heike, Kraus, Andreas, Schettina, Peter, Niemann, Catherin
    Nat Commun, 2015-01-22;6(0):5874.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  126. Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration.
    Authors: Moyon S, Dubessy A, Aigrot M, Trotter M, Huang J, Dauphinot L, Potier M, Kerninon C, Melik Parsadaniantz S, Franklin R, Lubetzki C
    J Neurosci, 2015-01-07;35(1):4-20.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  127. Antigen dependently activated cluster of differentiation 8-positive T cells cause perforin-mediated neurotoxicity in experimental stroke.
    Authors: Mracsko E, Liesz A, Stojanovic A, Lou W, Osswald M, Zhou W, Karcher S, Winkler F, Martin-Villalba A, Cerwenka A, Veltkamp R
    J Neurosci, 2014-12-10;34(50):16784-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  128. Epidermal growth factor attenuates tubular necrosis following mercuric chloride damage by regeneration of indigenous, not bone marrow-derived cells.
    Authors: Yen T, Alison M, Goodlad R, Otto W, Jeffery R, Cook H, Wright N, Poulsom R
    J Cell Mol Med, 2014-11-11;19(2):463-73.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  129. Differential sensitivity of prefrontal cortex and hippocampus to alcohol-induced toxicity.
    Authors: Fowler, Anna-Kat, Thompson, Jeremy, Chen, Lixia, Dagda, Marisela, Dertien, Janet, Dossou, Katina S, Moaddel, Ruin, Bergeson, Susan E, Kruman, Inna I
    PLoS ONE, 2014-09-04;9(9):e106945.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  130. Erythropoietin suppresses the activation of pro-apoptotic genes in head and neck squamous cell carcinoma xenografts exposed to surgical trauma.
    Authors: Lindgren G, Ekblad L, Vallon-Christersson J, Kjellen E, Gebre-Medhin M, Wennerberg J
    BMC Cancer, 2014-09-02;14(0):648.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  131. Short term morphine exposure in vitro alters proliferation and differentiation of neural progenitor cells and promotes apoptosis via mu receptors.
    Authors: Willner D, Cohen-Yeshurun A, Avidan A, Ozersky V, Shohami E, Leker R
    PLoS ONE, 2014-07-29;9(7):e103043.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  132. Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity.
    Authors: Park D, Lee J, Park I, Choi D, Lee S, Song S, Hwang Y, Hong K, Nakaoka Y, Makinen T, Kim P, Alitalo K, Hong Y, Koh G
    J Clin Invest, 2014-07-25;124(9):3960-74.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  133. LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea.
    Authors: Deng M, Luo X, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan A, Gan L
    J Neurosci, 2014-07-23;34(30):10072-7.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  134. mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress.
    Authors: Grahammer F, Haenisch N, Steinhardt F, Sander L, Roerden M, Arnold F, Cordts T, Wanner N, Reichardt W, Kerjaschki D, Ruegg M, Hall M, Moulin P, Busch H, Boerries M, Walz G, Artunc F, Huber T
    Proc Natl Acad Sci U S A, 2014-06-23;111(27):E2817-26.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  135. Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-beta.
    Authors: Wiener Z, Band A, Kallio P, Hogstrom J, Hyvonen V, Kaijalainen S, Ritvos O, Haglund C, Kruuna O, Robine S, Louvard D, Ben-Neriah Y, Alitalo K
    Proc Natl Acad Sci U S A, 2014-05-13;111(21):E2229-36.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Tissue
    Applications: Flow Cytometry, IHC
  136. Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin.
    Authors: Krabbe C, Bak S, Jensen P, von Linstow C, Martinez Serrano A, Hansen C, Meyer M
    PLoS ONE, 2014-05-02;9(5):e96465.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  137. Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function.
    Authors: Kumar L, Chou J, Yee C, Borzutzky A, Vollmann E, von Andrian U, Park S, Hollander G, Manis J, Poliani P, Geha R
    J Exp Med, 2014-04-21;211(5):929-42.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  138. Essential role for the TRF2 telomere protein in adult skin homeostasis.
    Authors: Martinez P, Ferrara-Romeo I, Flores J, Blasco M
    Aging Cell, 2014-04-14;13(4):656-68.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  139. Pseudomonas aeruginosa-induced apoptosis in airway epithelial cells is mediated by gap junctional communication in a JNK-dependent manner.
    Authors: Losa D, Kohler T, Bellec J, Dudez T, Crespin S, Bacchetta M, Boulanger P, Hong S, Morel S, Nguyen T, van Delden C, Chanson M
    J Immunol, 2014-04-14;192(10):4804-12.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  140. Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers.
    Authors: Edlund R, Ohyama T, Kantarci H, Riley B, Groves A
    Dev Biol, 2014-03-18;390(1):1-13.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  141. Germline quality control: eEF2K stands guard to eliminate defective oocytes.
    Authors: Chu H, Liao Y, Novak J, Hu Z, Merkin J, Shymkiv Y, Braeckman B, Dorovkov M, Nguyen A, Clifford P, Nagele R, Harrison D, Ellis R, Ryazanov A
    Dev Cell, 2014-02-27;28(5):561-72.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  142. Mechanism of cystogenesis in nephrotic kidneys: a histopathological study.
    Authors: Saraga M, Vukojevic K, Krzelj V, Puretic Z, Bocina I, Durdov M, Weber S, Dworniczak B, Ljubanovic D, Saraga-Babic M
    BMC Nephrol, 2014-01-08;15(0):3.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  143. Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate.
    Authors: Brookes, Steven J, Barron, Martin J, Boot-Handford, Ray, Kirkham, Jennifer, Dixon, Michael
    Hum Mol Genet, 2013-12-20;23(9):2468-80.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  144. Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
    Authors: Fan J, Ponferrada V, Sato T, Vemaraju S, Fruttiger M, Gerhardt H, Ferrara N, Lang R
    Development, 2013-12-18;141(2):448-59.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  145. The extracellular matrix glycoprotein tenascin-R regulates neurogenesis during development and in the adult dentate gyrus of mice.
    Authors: Xu J, Xiao M, Jakovcevski I, Sivukhina E, Hargus G, Cui Y, Irintchev A, Schachner M, Bernreuther C
    J Cell Sci, 2013-12-11;127(0):641-52.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  146. Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid.
    Authors: Tzeng, Tsai-Ten, Tsay, Huey-Jen, Chang, Luping, Hsu, Chia-Lin, Lai, Tzu-Hsua, Huang, Fong-Lee, Shiao, Young-Ji
    J Biomed Sci, 2013-12-06;20(0):90.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  147. Biphasic influence of Miz1 on neural crest development by regulating cell survival and apical adhesion complex formation in the developing neural tube.
    Authors: Kerosuo L, Bronner M
    Mol Biol Cell, 2013-12-04;25(3):347-55.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: IHC
  148. The temporal and spatial profiles of cell loss following experimental spinal cord injury: effect of antioxidant therapy on cell death and functional recovery.
    Authors: Ling, Xiang, Bao, Feng, Qian, Hao, Liu, Danxia
    BMC Neurosci, 2013-11-18;14(0):146.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  149. Requirements for Aurora-A in tissue regeneration and tumor development in adult mammals.
    Authors: Perez de Castro I, Aguirre-Portoles C, Fernandez-Miranda G, Canamero M, Cowley D, Van Dyke T, Malumbres M
    Cancer Res, 2013-11-15;73(22):6804-15.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  150. Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death.
    Authors: Wahlin, Karl J, Enke, Raymond, Fuller, John A, Kalesnykas, Giedrius, Zack, Donald J, Merbs, Shannath
    PLoS ONE, 2013-11-11;8(11):e79140.
    Species: Chicken, Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  151. A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.
    Authors: Olive V, Sabio E, Bennett M, De Jong C, Biton A, McGann J, Greaney S, Sodir N, Zhou A, Balakrishnan A, Foth M, Luftig M, Goga A, Speed T, Xuan Z, Evan G, Wan Y, Minella A, He L
    Elife, 2013-10-15;2(0):e00822.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  152. Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERalpha(+) tumorigenesis.
    Authors: Chan S, Rickert C, Vermi W, Sheehan K, Arthur C, Allen J, White J, Archambault J, Lonardi S, McDevitt T, Bhattacharya D, Lorenzi M, Allred D, Schreiber R
    Cell Death Differ, 2013-09-13;21(2):234-46.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  153. Increased chondrocyte apoptosis is associated with progression of osteoarthritis in spontaneous Guinea pig models of the disease.
    Authors: Zamli Z, Adams M, Tarlton J, Sharif M
    Int J Mol Sci, 2013-08-29;14(9):17729-43.
    Species: Guinea Pig
    Sample Types: Whole Tissue
    Applications: IHC
  154. Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.
    Authors: Stott, Simon R, Metzakopian, Emmanoui, Lin, Wei, Kaestner, Klaus H, Hen, Rene, Ang, Siew-Lan
    J Neurosci, 2013-05-01;33(18):8022-34.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  155. Diet-induced obesity exacerbates auditory degeneration via hypoxia, inflammation, and apoptosis signaling pathways in CD/1 mice.
    Authors: Hwang J, Hsu C, Yu W, Liu T, Yang W
    PLoS ONE, 2013-04-26;8(4):e60730.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  156. Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-kappaB and Src protein kinase signaling pathways.
    Authors: Shakibaei M, Mobasheri A, Lueders C, Busch F, Shayan P, Goel A
    PLoS ONE, 2013-02-22;8(2):e57218.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  157. Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis.
    Cell Death Differ., 2012-05-04;19(11):1761-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  158. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy.
    Authors: McIntyre A, Patiar S, Wigfield S
    Clin. Cancer Res., 2012-04-12;18(11):3100-11.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  159. An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration.
    Authors: Chen T, Heller E, Beronja S, Oshimori N, Stokes N, Fuchs E
    Nature, 2012-04-04;485(7396):104-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  160. Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation.
    Authors: Fuxe J, Tabruyn S, Colton K, Zaid H, Adams A, Baluk P, Lashnits E, Morisada T, Le T, O'Brien S, Epstein DM, Koh GY, McDonald DM
    Am. J. Pathol., 2011-05-06;178(6):2897-909.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  161. Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain.
    Authors: Hernandez-Miranda LR, Cariboni A, Faux C, Ruhrberg C, Cho JH, Cloutier JF, Eickholt BJ, Parnavelas JG, Andrews WD
    J. Neurosci., 2011-04-20;31(16):6174-87.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  162. Two hypomorphic alleles of mouse Ass1 as a new animal model of citrullinemia type I and other hyperammonemic syndromes.
    Authors: Perez CJ, Jaubert J, Guenet JL, Barnhart KF, Ross-Inta CM, Quintanilla VC, Aubin I, Brandon JL, Otto NW, DiGiovanni J, Gimenez-Conti I, Giulivi C, Kusewitt DF, Conti CJ, Benavides F
    Am. J. Pathol., 2010-08-19;177(4):1958-68.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  163. Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death.
    Authors: Sotiropoulou PA, Candi A, Mascre G, De Clercq S, Youssef KK, Lapouge G, Dahl E, Semeraro C, Denecker G, Marine JC, Blanpain C
    Nat. Cell Biol., 2010-05-16;12(6):572-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  164. MicroRNA-183 family members regulate sensorineural fates in the inner ear.
    Authors: Li H, Kloosterman W, Fekete DM
    J. Neurosci., 2010-03-03;30(9):3254-63.
    Species: Zebrafish
    Sample Types: Whole Tissue
    Applications: IHC
  165. Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.
    Authors: Hashizume H, Falcon BL, Kuroda T, Baluk P, Coxon A, Yu D, Bready JV, Oliner JD, McDonald DM
    Cancer Res., 2010-03-02;70(6):2213-23.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  166. ALK1 signaling regulates early postnatal lymphatic vessel development.
    Authors: Niessen K, Zhang G, Ridgway JB, Chen H, Yan M
    Blood, 2009-11-10;115(8):1654-61.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  167. Mitogen-activated protein kinase-signaling regulates the ability of Muller glia to proliferate and protect retinal neurons against excitotoxicity.
    Authors: Fischer AJ, Scott MA, Ritchey ER, Sherwood P
    Glia, 2009-11-01;57(14):1538-52.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  168. Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain.
    Authors: Yawno T, Hirst JJ, Castillo-Melendez M, Walker DW
    Neuroscience, 2009-07-08;163(3):838-47.
    Species: Ovine
    Sample Types: Whole Tissue
    Applications: IHC-P
  169. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease.
    Authors: Borchers MT, Wesselkamper SC, Curull V, Ramirez-Sarmiento A, Sanchez-Font A, Garcia-Aymerich J, Coronell C, Lloreta J, Agusti AG, Gea J, Howington JA, Reed MF, Starnes SL, Harris NL, Vitucci M, Eppert BL, Motz GT, Fogel K, McGraw DW, Tichelaar JW, Orozco-Levi M
    J. Clin. Invest., 2009-02-09;119(3):636-49.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  170. Repeated ethanol exposure during late gestation alters the maturation and innate immune status of the ovine fetal lung.
    Authors: Sozo F, O'Day L, Maritz G, Kenna K, Stacy V, Brew N, Walker D, Bocking A, Brien J, Harding R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2008-12-26;296(3):L510-8.
    Species: Ovine
    Sample Types: Whole Tissue
    Applications: IHC-P
  171. A functional interaction between Irx and Meis patterns the anterior hindbrain and activates krox20 expression in rhombomere 3.
    Authors: Stedman A, Lecaudey V, Havis E, Anselme I, Wassef M, Gilardi-Hebenstreit P, Schneider-Maunoury S
    Dev. Biol., 2008-12-25;327(2):566-77.
    Species: Zebrafish
    Sample Types: Whole Tissue
    Applications: IHC
  172. Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins.
    Authors: Michaelis M, Bliss J, Arnold SC, Hinsch N, Rothweiler F, Deubzer HE, Witt O, Langer K, Doerr HW, Wels WS, Cinatl J
    Clin. Cancer Res., 2008-10-15;14(20):6531-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  173. The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis.
    Authors: Heckman CA, Holopainen T, Wirzenius M, Keskitalo S, Jeltsch M, Yla-Herttuala S, Wedge SR, Jurgensmeier JM, Alitalo K
    Cancer Res., 2008-06-15;68(12):4754-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  174. Cystic fibrosis transmembrane conductance regulator controls lung proteasomal degradation and nuclear factor-kappaB activity in conditions of oxidative stress.
    Authors: Boncoeur E, Roque T, Bonvin E, Saint-Criq V, Bonora M, Clement A, Tabary O, Henrion-Caude A, Jacquot J
    Am. J. Pathol., 2008-03-27;172(5):1184-94.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  175. Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres.
    Authors: Siegl-Cachedenier I, Flores I, Klatt P, Blasco MA
    J. Cell Biol., 2007-10-22;179(2):277-90.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  176. Cytotoxic action of phorbol esters on human pancreatic cancer cells.
    Authors: Bond JA, Gescher AJ, Verschoyle RD, Lemoine NR, Errington R, Wiltshire M, Smith PJ, Wynford-Thomas D
    Int. J. Cancer, 2007-10-01;121(7):1445-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  177. Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis.
    Authors: Benosman S, Gross I, Clarke N, Jochemsen AG, Okamoto K, Loeffler JP, Gaiddon C
    Cell Death Differ., 2007-09-07;14(12):2047-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  178. Cytochemical and ultrastructural study of anoikis and secondary necrosis in enterocytes detached in vivo.
    Authors: do Vale A, Costa-Ramos C, Silva DS, Macedo PM, Fernandes R, Sampaio P, Dos Santos NM, Silva MT
    Apoptosis, 2007-06-01;12(6):1069-83.
    Species: Fish
    Sample Types: Whole Tissue
    Applications: IHC-P
  179. Gam1-associated alterations of drug responsiveness through activation of apoptosis.
    Authors: Wu F, Chiocca S, Beck WT, Mo YY
    Mol. Cancer Ther., 2007-06-01;6(6):1823-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  180. Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep.
    Authors: Yawno T, Yan EB, Walker DW, Hirst JJ
    Neuroscience, 2007-04-20;146(4):1726-33.
    Species: Ovine
    Sample Types: Whole Tissue
    Applications: IHC-P
  181. Protein C is an autocrine growth factor for human skin keratinocytes.
    Authors: Xue M, Campbell D, Jackson CJ
    J. Biol. Chem., 2007-02-09;282(18):13610-6.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  182. Loss of vascular endothelial growth factor expression reduces vascularization, but not growth, of tumors lacking the Von Hippel-Lindau tumor suppressor gene.
    Authors: Blouw B, Haase VH, Song H, Bergers G, Johnson RS
    Oncogene, 2007-02-05;26(31):4531-40.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  183. Involvement of the Edar signaling in the control of hair follicle involution (catagen).
    Authors: Fessing MY, Sharova TY, Sharov AA, Atoyan R, Botchkarev VA
    Am. J. Pathol., 2006-12-01;169(6):2075-84.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  184. Invasive trophoblasts stimulate vascular smooth muscle cell apoptosis by a fas ligand-dependent mechanism.
    Authors: Harris LK, Keogh RJ, Wareing M, Baker PN, Cartwright JE, Aplin JD, Whitley GS
    Am. J. Pathol., 2006-11-01;169(5):1863-74.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  185. Canonical notch signaling functions as a commitment switch in the epidermal lineage.
    Authors: Blanpain C, Lowry WE, Pasolli HA, Fuchs E
    Genes Dev., 2006-11-01;20(21):3022-35.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  186. Tendon-muscle crosstalk controls muscle bellies morphogenesis, which is mediated by cell death and retinoic acid signaling.
    Authors: Rodriguez-Guzman M, Montero JA, Santesteban E, Ganan Y, Macias D, Hurle JM
    Dev. Biol., 2006-09-26;302(1):267-80.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: IHC
  187. Evolution of the androgen receptor pathway during progression of prostate cancer.
    Authors: Hendriksen PJ, Dits NF, Kokame K, Veldhoven A, van Weerden WM, Bangma CH, Trapman J, Jenster G
    Cancer Res., 2006-05-15;66(10):5012-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  188. Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice.
    Authors: Jacomy H, Fragoso G, Almazan G, Mushynski WE, Talbot PJ
    Virology, 2006-03-09;349(2):335-46.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  189. Mechanisms of apoptosis after ischemia and reperfusion: role of the renin-angiotensin system.
    Authors: Kossmehl P, Kurth E, Faramarzi S, Habighorst B, Shakibaei M, Wehland M, Kreutz R, Infanger M, J Danser AH, Grosse J, Paul M, Grimm D
    Apoptosis, 2006-03-01;11(3):347-58.
    Species: Porcine
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  190. Wnt signals mediate a fate decision between otic placode and epidermis.
    Authors: Ohyama T, Mohamed OA, Taketo MM, Dufort D, Groves AK
    Development, 2006-02-01;133(5):865-75.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  191. Expression and functional analysis of Bax inhibitor-1 in human breast cancer cells.
    Authors: Grzmil M, Kaulfuss S, Thelen P, Hemmerlein B, Schweyer S, Obenauer S, Kang TW, Burfeind P
    J. Pathol., 2006-02-01;208(3):340-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  192. Helicobacter felis and Helicobacter bizzozeronii induce gastric parietal cell loss in Mongolian gerbils.
    Authors: De Bock M, Decostere A, Hellemans A, Haesebrouck F, Ducatelle R
    Microbes Infect., 2005-10-11;8(2):503-10.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  193. Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation.
    Authors: Gueders MM, Balbin M, Rocks N, Foidart JM, Gosset P, Louis R, Shapiro S, Lopez-Otin C, Noel A, Cataldo DD
    J. Immunol., 2005-08-15;175(4):2589-97.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  194. Higher resistance of porcine trigeminal ganglion neurons towards pseudorabies virus-induced cell death compared with other porcine cell types in vitro.
    Authors: Geenen K, Favoreel HW, Nauwynck HJ
    J. Gen. Virol., 2005-05-01;86(0):1251-60.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: ICC
  195. Effects of systemically administered NT-3 on sensory neuron loss and nestin expression following axotomy.
    Authors: Kuo LT, Simpson A, Schanzer A, Tse J, An SF, Scaravilli F, Groves MJ
    J. Comp. Neurol., 2005-02-21;482(4):320-32.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  196. Apoptosis and active caspase-3 expression in human granulosa cells.
    Authors: Glamoclija V, Vilovic K, Saraga-Babic M, Baranovic A, Sapunar D
    Fertil. Steril., 2005-02-01;83(2):426-31.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC-P
  197. The pseudorabies virus US3 protein kinase possesses anti-apoptotic activity that protects cells from apoptosis during infection and after treatment with sorbitol or staurosporine.
    Authors: Geenen K, Favoreel HW, Olsen L, Enquist LW, Nauwynck HJ
    Virology, 2005-01-05;331(1):144-50.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: ICC
  198. Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block.
    Authors: Salomonsson S, Sonesson SE, Ottosson L, Muhallab S, Olsson T, Sunnerhagen M, Kuchroo VK, Thoren P, Herlenius E, Wahren-Herlenius M
    J. Exp. Med., 2005-01-03;201(1):11-7.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  199. Lactate dehydrogenase-elevating virus induces apoptosis in cultured macrophages and in spinal cords of C58 mice coincident with onset of murine amyotrophic lateral sclerosis.
    Authors: Zitterkopf NL, McNeal DW, Eyster KM, Bradley DS, Cafruny WA
    Virus Res., 2004-11-01;106(1):35-42.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC-Fr
  200. Analysis of central regulatory pathways in p53-deficient primary cultures of malignant fibrous histiocytoma exposed to ifosfamide.
    Authors: Schlott T, Taubert H, Fayyazi A, Schweyer S, Bartel F, Korabiowska M, Brinck U
    Anticancer Res., 2004-11-01;24(6):3819-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  201. Evidence of caspase-3 activation in hyposmotic stress-induced necrosis.
    Authors: Niquet J, Allen SG, Baldwin RA, Wasterlain CG
    Neurosci. Lett., 2004-02-19;356(3):225-7.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  202. Blockade of the type I IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3, and suppresses MMP-2 expression.
    Authors: Grzmil M, Hemmerlein B, Thelen P, Schweyer S, Burfeind P
    J. Pathol., 2004-01-01;202(1):50-9.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: ICC
  203. Early events in the anoikis program occur in the absence of caspase activation.
    Authors: Wang P, Valentijn AJ, Gilmore AP, Streuli CH
    J. Biol. Chem., 2003-03-05;278(22):19917-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC

FAQs

  1. What is the genus of rabbit used to produce Human/Mouse Active Caspase-3 Antibody, Catalog # AF835? 

    • The genus is Oryctolagus cuniculus.

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Reviews for Human/Mouse Active Caspase-3 Antibody

Average Rating: 4.8 (Based on 5 Reviews)

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Human/Mouse Active Caspase-3 Antibody
By Anonymous on 07/20/2021
Application: IHC Sample Tested: Kidney tissue Species: Mouse
Immunohistochemistry Human/Mouse Active Caspase-3 Antibody AF835
Human/Mouse Active Caspase-3 Antibody
By Anonymous on 07/09/2021
Application: ICC/IF Sample Tested: Squamous cell carcinoma (OSCC) cells Species: Mouse
Immunocytochemistry/Immunofluorescence Human/Mouse Active Caspase-3 Antibody AF835
Human/Mouse Active Caspase-3 Antibody
By Anonymous on 02/15/2021
Application: IHC Sample Tested: Small intestine Species: Mouse
Immunohistochemistry Human/Mouse Active Caspase-3 Antibody AF835
Human/Mouse Active Caspase-3 Antibody
By Anonymous on 12/22/2017
Application: ICC/IF Sample Tested: Spleen tissue Species: Mouse

Used to check for apoptose of macrophages

Immunocytochemistry/Immunofluorescence Human/Mouse Active Caspase-3 Antibody AF835
Human/Mouse Active Caspase-3 Antibody
By Liz Bishop on 05/17/2017
Application: IHC Sample Tested: Brain (hippocampus) Species: Rat

Active Caspase-3 (red) on fresh frozen, formaldehyde-fixed 10um sections of CA3 region of hippocampus. Good signal, but difficult to image because of high background from NeuN (green).

Immunohistochemistry Human/Mouse Active Caspase-3 Antibody AF835