Human/Mouse/Rat SOX2 Antibody

Catalog # Availability Size / Price Qty
MAB2018
MAB2018-SP
Best Seller
E‑Cadherin and SOX2 in BG01V Human Stem Cells.
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Product Details
Citations (182)
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Human/Mouse/Rat SOX2 Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human, mouse, and rat SOX2 in Western blots.
Source
Monoclonal Mouse IgG2A Clone # 245610
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human SOX2
Gly135-Met317
Accession # P48431
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
See below
Simple Western
4 µg/mL
See below
Immunohistochemistry
3-15 µg/mL
Immersion fixed paraffin-embedded sections of glioblastoma
CyTOF-reported
Zunder, E.R. et al. (2015) Cell Stem Cell 16: 323. Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Immunocytochemistry
8-25 µg/mL
See below
Intracellular Staining by Flow Cytometry
0.25 µg/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunocytochemistry E-Cadherin and SOX2 antibody in BG01V Human Stem Cells by Immunocytochemistry (ICC). View Larger

E‑Cadherin and SOX2 in BG01V Human Stem Cells. E-Cadherin and SOX2 were detected in BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human E-Cadherin Antigen Affinity-purified Polyclonal Antibody (AF648) and 10 µg/mL Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for E-Cadherin using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and for SOX2 using the NorthernLights 493-conjugated Anti-Mouse Secondary Antibody (green; NL009). Cells were counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Western Blot Detection of Human, Mouse, and Rat SOX2 antibody by Western Blot. View Larger

Detection of Human, Mouse, and Rat SOX2 by Western Blot. Western blot shows lysates of NTera-2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, D3 mouse embryonic stem cell line, and rat cortical stem cells. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (HAF018). A specific band was detected for SOX2 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunocytochemistry SOX2 antibody in BG01V Human Embryonic Stem Cells by Immunocytochemistry (ICC). View Larger

SOX2 in BG01V Human Embryonic Stem Cells. SOX2 was detected in immersion fixed BG01V human embryonic stem cells using Mouse Anti-Human/ Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (yellow; NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Intracellular Staining by Flow Cytometry Detection of SOX2 antibody in NTera-2 Human Cell Line antibody by Flow Cytometry. View Larger

Detection of SOX2 in NTera‑2 Human Cell Line by Flow Cytometry. NTera-2 human testicular embryonic carcinoma cell line was stained with Mouse Anti-Human/ Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018, filled histogram) or isotype control antibody (MAB003, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (F0102B). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (FC005). View our protocol for Staining Intracellular Molecules.

Simple Western Detection of Human SOX2 antibody by Simple Western<SUP>TM</SUP>. View Larger

Detection of Human SOX2 by Simple WesternTM. Simple Western lane view shows lysates of BG01V human embryonic stem cells, loaded at 0.2 mg/mL. A specific band was detected for SOX2 at approximately 50 kDa (as indicated) using 4 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Immunohistochemistry View Larger

Detection of SOX2 in glioblastoma. SOX2 was detected in immersion fixed paraffin-embedded sections of glioblastoma using Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to nuclei in cancer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SOX2

SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-6).

References
  1. Graham, V. et al. (2003) Neuron 39:749.
  2. Avilion, A.A. et al. (2003) Genes Dev. 17:126.
  3. Kishi, M. et al. (2000) Development 127:791.
  4. Yuan, H. et al. (1995) Genes Dev. 9:2635.
  5. Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
  6. Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.
Long Name
Transcription Factor SOX2
Entrez Gene IDs
6657 (Human)
Alternate Names
ANOP3; MCOPS3; MGC2413; SOX2; SRY (sex determining region Y)-box 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2

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Citations for Human/Mouse/Rat SOX2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

182 Citations: Showing 1 - 10
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  1. Synaptic plasticity in human thalamocortical assembloids.
    Authors: Mary H Patton, Kristen T Thomas, Ildar T Bayazitov, Kyle D Newman, Nathaniel B Kurtz, Camenzind G Robinson, Cody A Ramirez, Alexandra J Trevisan, Jay B Bikoff, Samuel T Peters, Shondra M Pruett-Miller, Yanbo Jiang, Andrew B Schild, Anjana Nityanandam, Stanislav S Zakharenko
    Cell Rep
    Species: Human
    Sample Types: Organoid
    Applications: Immunohistochemistry
  2. Derivation of an induced pluripotent stem cell line (FDCHi014-A) from PBMCs of a seven-year-old patient with a truncating NOVA2 variant (c.625del)
    Authors: Yin, T;Qian, Y;Zhang, X;Liao, Y;Wu, B;Wang, S;Wang, H;
    Stem cell research
    Species: Human hepegivirus
    Sample Types: Whole Cells
    Applications: Immunocytochemistry
  3. Elevated FOXG1 in glioblastoma stem cells cooperates with Wnt/?-catenin to induce exit from quiescence
    Authors: Robertson, FL;O'Duibhir, E;Gangoso, E;Bressan, RB;Bulstrode, H;Marqu�s-Torrej�n, M�;Ferguson, KM;Blin, C;Grant, V;Alfazema, N;Morrison, GM;Pollard, SM;
    Cell reports
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  4. Generation of induced pluripotent stem cell line (UKWNLi008) derived from a patient carrying a c.1678C>G variant in the transient receptor potential cation channel subfamily A member (TRPA1) gene potentially associated with small fiber neuropathy
    Authors: NM Schottmann, K Klug, E Klopocki, N Üçeyler
    Stem Cell Research, 2023-04-12;69(0):103094.
    Species: Human
    Sample Types: Transfected Whole Cells
    Applications: ICC
  5. Generation of an induced pluripotent stem cell line from an aortic dissection patient carrying MCTP2/c.2635T�>�G mutation
    Authors: W Feng, C Li, Y Li, J Yang, R Fan
    Stem Cell Research, 2023-02-26;68(0):103058.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages
    Authors: MF Wells, J Nemesh, S Ghosh, JM Mitchell, MR Salick, CJ Mello, D Meyer, O Pietilaine, F Piccioni, EJ Guss, K Raghunatha, M Tegtmeyer, D Hawes, A Neumann, KA Worringer, D Ho, S Kommineni, K Chan, BK Peterson, JJ Raymond, JT Gold, MT Siekmann, E Zuccaro, R Nehme, A Kaykas, K Eggan, SA McCarroll
    Cell Stem Cell, 2023-02-15;0(0):.
    Species: Human
    Sample Types: Organoid, Whole Cells
    Applications: ICC, IHC
  7. Identification of therapeutic sensitivities in a spheroid drug combination screen of Neurofibromatosis Type I associated High Grade Gliomas
    Authors: J Dougherty, K Harvey, A Liou, K Labella, D Moran, S Brosius, T De Raedt
    PLoS ONE, 2023-02-02;18(2):e0277305.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  8. Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation
    Authors: KW Govek, S Chen, P Sgourdou, Y Yao, S Woodhouse, T Chen, MV Fuccillo, DJ Epstein, PG Camara
    Cell Reports, 2022-12-06;41(10):111768.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  9. CHRDL1 Regulates Stemness in Glioma Stem-like Cells
    Authors: I Berglar, S Hehlgans, A Wehle, C Roth, C Herold-Men, F Rödel, D Kögel, B Linder
    Cells, 2022-12-03;11(23):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  10. A TNFR1-UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop
    Authors: Z Xiao, G Shi, S Xi, AK Singh, J Willette-B, X Li, F Zhu, L Su, X Wu, DS Schrump, Y Hu
    Cell Death & Disease, 2022-10-21;13(10):885.
    Species: Moose
    Sample Types: Cell Lysates
    Applications: Western Blot
  11. Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for beta cell replacement
    Authors: R Chimienti, T Baccega, S Torchio, F Manenti, S Pellegrini, A Cospito, A Amabile, MT Lombardo, P Monti, V Sordi, A Lombardo, M Malnati, L Piemonti
    Cell Reports, 2022-09-27;40(13):111423.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  12. SerpinB3 drives cancer stem cell survival in glioblastoma
    Authors: A Lauko, J Volovetz, SM Turaga, D Bayik, DJ Silver, K Mitchell, EE Mulkearns-, DC Watson, K Desai, M Midha, J Hao, K McCortney, A Steffens, U Naik, MS Ahluwalia, S Bao, C Horbinski, JS Yu, JD Lathia
    Cell Reports, 2022-09-13;40(11):111348.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  13. Inhibition of the Phospholipase Cepsilon-c-Jun N-Terminal Kinase Axis Suppresses Glioma Stem Cell Properties
    Authors: M Okada, Y Nakagawa-S, Y Mitobe, A Sugai, K Togashi, S Suzuki, C Kitanaka
    International Journal of Molecular Sciences, 2022-08-07;23(15):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Western Blot
  14. p38 MAPK-dependent phosphorylation of transcription factor SOX2 promotes an adaptive response to BRAF inhibitors in melanoma cells
    Authors: S Pietrobono, R De Paolo, D Mangiameli, A Marranci, I Battisti, C Franchin, G Arrigoni, D Melisi, L Poliseno, B Stecca
    The Journal of Biological Chemistry, 2022-08-07;298(9):102353.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP, Immunoprecipitation
  15. A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development
    Authors: V Benedetti, F Banfi, M Zaghi, R Moll-Diaz, L Massimino, L Argelich, E Bellini, S Bido, S Muggeo, G Ordazzo, G Mastrotota, M Moneta, A Sessa, V Broccoli
    Science Advances, 2022-08-03;8(31):eabn3986.
    Species: Human
    Sample Types: Cell Lysate
    Applications: Western Blot
  16. HDAC Class I Inhibitor Domatinostat Preferentially Targets Glioma Stem Cells over Their Differentiated Progeny
    Authors: Y Nakagawa-S, S Saitoh, Y Mitobe, A Sugai, K Togashi, S Suzuki, C Kitanaka, M Okada
    International Journal of Molecular Sciences, 2022-07-22;23(15):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  17. Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient
    Authors: J Lotila, T Hyvärinen, H Skottman, L Airas, S Narkilahti, S Hagman
    Oncogene, 2022-07-11;63(0):102865.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  18. Integrating Oxygen and 3D Cell Culture System: A Simple Tool to Elucidate the Cell Fate Decision of hiPSCs
    Authors: RR Khadim, RK Vadivelu, T Utami, FG Torizal, M Nishikawa, Y Sakai
    International Journal of Molecular Sciences, 2022-06-30;23(13):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  19. Changes in the Expression of Smooth Muscle Cell-Related Genes in Human Dermal Sheath Cup Cells Associated with the Treatment Outcome of Autologous Cell-Based Therapy for Male and Female Pattern Hair Loss
    Authors: Y Yoshida, M Takahashi, H Yamanishi, Y Nakazawa, J Kishimoto, M Ohyama
    International Journal of Molecular Sciences, 2022-06-27;23(13):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  20. Identification of adeno-associated virus variants for gene transfer into human neural cell types by parallel capsid screening
    Authors: LJ Flitsch, K Börner, C Stüllein, S Ziegler, V Sonntag-Bu, E Wiedtke, V Semkova, SWC Au Yeung, J Schlee, M Hajo, M Mathews, BS Ludwig, S Kossatz, H Kessler, D Grimm, O Brüstle
    Scientific Reports, 2022-05-19;12(1):8356.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  21. Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Cav1.3-encoding CACNA1D gene
    Authors: M Tisch, M Carmen De, M Suarez-Cub, C Fauth, M Defrancesc, J Zschocke, K Günther, F Edenhofer
    Stem Cell Research, 2022-04-09;61(0):102784.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  22. Generation and characterization of induced pluripotent stem cell line (IBBISTi004-A) from an Angelman syndrome patient carrying a class II deletion of the maternal chromosome 15q11.2-q13
    Authors: C Maranga, C Pereira, AC Raposo, A Vieira, S Duarte, EP Bekman, I Milagre, ST da Rocha
    Stem Cell Research, 2022-03-21;61(0):102757.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  23. Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A�>�G of unknown pathogenicity in Fabry disease
    Authors: M Breyer, T Klein, K Klug, E Klopocki, N Üçeyler
    Stem Cell Research, 2022-03-14;61(0):102747.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  24. Differences in stem cell marker and osteopontin expression in primary and recurrent glioblastoma
    Authors: B Polat, G Wohlleben, R Kosmala, D Lisowski, F Mantel, V Lewitzki, M Löhr, R Blum, P Herud, M Flentje, CM Monoranu
    Cancer Cell International, 2022-02-19;22(1):87.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  25. Smoothened/AMP-Activated Protein Kinase Signaling in Oligodendroglial Cell Maturation
    Authors: A Del Giovan, M Russo, L Tirou, H Faure, M Ruat, S Balestri, C Sposato, F Basoli, A Rainer, A Kassoussi, E Traiffort, A Ragnini-Wi
    Frontiers in Cellular Neuroscience, 2022-01-10;15(0):801704.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  26. G-quadruplex DNA structures in human stem cells and differentiation
    Authors: KG Zyner, A Simeone, SM Flynn, C Doyle, G Marsico, S Adhikari, G Portella, D Tannahill, S Balasubram
    Nature Communications, 2022-01-10;13(1):142.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  27. Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats
    Authors: IC Han, LR Bohrer, KN Gibson-Cor, LA Wiley, A Shrestha, BE Harman, C Jiao, EH Sohn, R Wendland, BN Allen, KS Worthingto, RF Mullins, EM Stone, BA Tucker
    Cell Transplantation, 2022-01-01;31(0):9636897221104.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  28. Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids
    Authors: M Notaras, A Lodhi, F Dündar, P Collier, NM Sayles, H Tilgner, D Greening, D Colak
    Molecular Psychiatry, 2021-11-17;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  29. Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis
    Authors: F Pecori, N Kondo, C Ogura, T Miura, M Kume, Y Minamijima, K Yamamoto, S Nishihara
    Cell Reports, 2021-07-13;36(2):109361.
    Species: Human, Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  30. Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936�T�>�A) mutation in JAGGED-1
    Authors: BM Brooks, M Pradhan, YS Cheng, K Gorshkov, A Farkhondeh, CZ Chen, J Beers, C Liu, K Baumgaerte, S Rodems, W Zheng
    Stem Cell Research, 2021-06-24;54(0):102447.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  31. Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids
    Authors: M Notaras, A Lodhi, E Barrio-Alo, C Foord, T Rodrick, D Jones, H Fang, D Greening, D Colak
    Molecular Psychiatry, 2021-06-22;0(0):.
    Species: Human
    Sample Types: Organoids
    Applications: IHC
  32. Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls
    Authors: L Ma, M Schmidt, EM Morrow
    Stem Cell Research, 2021-06-18;54(0):102435.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  33. RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability
    Authors: F Xiong, R Wang, JH Lee, S Li, SF Chen, Z Liao, LA Hasani, PT Nguyen, X Zhu, J Krakowiak, DF Lee, L Han, KL Tsai, Y Liu, W Li
    Cell Research, 2021-06-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  34. Generation of an induced pluripotent stem cell line (TRNDi012-B) from Fibrodysplasia Ossificans Progressiva (FOP) patient carrying a heterozygous mutation c. 617G�>�A in the ACVR1 gene
    Authors: X Huang, A Roeder, R Li, J Beers, C Liu, J Zou, PB Yu, W Zheng
    Stem Cell Research, 2021-06-07;54(0):102424.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  35. Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway
    Authors: YC Lin, MS Kumar, N Ramesh, EN Anderson, AT Nguyen, B Kim, S Cheung, JA McDonough, WC Skarnes, R Lopez-Gonz, JE Landers, NL Fawzi, IRA Mackenzie, EB Lee, JA Nickerson, D Grunwald, UB Pandey, DA Bosco
    Nature Neuroscience, 2021-05-31;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  36. An induced pluripotent stem cell line (NCATS-CL9075) from a patient carrying compound heterozygote mutations, p.R390P and p.L318P, in the NGLY1 gene
    Authors: M Pradhan, A Farkhondeh, YS Cheng, M Xu, J Beers, J Zou, C Liu, M Might, S Rodems, K Baumgärtel, W Zheng
    Stem Cell Research, 2021-05-20;54(0):102400.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  37. Comparative evaluation of isogenic mesodermal and ectomesodermal chondrocytes from human iPSCs for cartilage regeneration
    Authors: MS Lee, MJ Stebbins, H Jiao, HC Huang, EM Leiferman, BE Walczak, SP Palecek, EV Shusta, WJ Li
    Science Advances, 2021-05-19;7(21):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  38. Generation of an induced pluripotent stem cell line (TRNDi030-A) from a patient with Farber disease carrying a homozygous p. Y36C (c. 107 A>G) mutation in ASAH1
    Authors: BM Brooks, CD Yeh, J Beers, C Liu, YS Cheng, K Gorshkov, J Zou, W Zheng, CZ Chen
    Stem Cell Research, 2021-05-12;53(0):102387.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  39. Generation of Alagille syndrome derived induced pluripotent stem cell line carrying heterozygous mutation in the JAGGED-1 gene at splicing site (Chr20: 10,629,709C>A) before exon 11
    Authors: W Zhu, YS Cheng, M Xu, A Farkhondeh, J Beers, J Zou, C Liu, K Baumgaerte, S Rodems, W Zheng
    Stem Cell Research, 2021-04-27;53(0):102366.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  40. Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation
    Authors: TP Silva, CA Pereira, AC Raposo, AR Oliveira, M Arez, JMS Cabral, I Milagre, M Carmo-Fons, STD Rocha
    Stem Cell Research, 2021-04-23;53(0):102364.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  41. Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis
    Authors: MA Khuu, T Nallamothu, CI Castro-Riv, A Arias-Cavi, CC Szujewski, AJ Garcia Iii
    Scientific Reports, 2021-03-16;11(1):6005.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  42. Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
    Authors: RB Bressan, B Southgate, KM Ferguson, C Blin, V Grant, N Alfazema, JC Wills, MA Marques-To, GM Morrison, J Ashmore, F Robertson, CAC Williams, L Bradley, A von Kriegs, RA Anderson, SR Tomlinson, SM Pollard
    Cell Stem Cell, 2021-02-24;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  43. Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c.3612delA
    Authors: TP Silva, CA Pereira, AR Oliveira, AC Raposo, M Arez, JMS Cabral, I Milagre, M Carmo-Fons, ST da Rocha
    Stem Cell Research, 2021-02-11;52(0):102242.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  44. Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties
    Authors: V Pasquale, G Ducci, G Campioni, A Ventrici, C Assalini, S Busti, M Vanoni, R Vago, E Sacco
    Cells, 2020-12-11;9(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  45. Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdown in human neurons
    Authors: ST Chen, WJ Lai, WJ Zhang, QP Chen, LB Zhou, KF So, LL Shi
    Neural Regen Res, 2020-12-01;15(12):2335-2343.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  46. ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL
    Authors: S Pietrobono, G Anichini, C Sala, F Manetti, LL Almada, S Pepe, RM Carr, BD Paradise, JN Sarkaria, JI Davila, L Tofani, I Battisti, G Arrigoni, L Ying, C Zhang, H Li, A Meves, ME Fernandez-, B Stecca
    Nat Commun, 2020-11-17;11(1):5865.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  47. Generation of an induced pluripotent stem cell line from an Alstr�m Syndrome patient with ALMS1 mutation (c.3902C�>�A, c.6436C�>�T) and a gene correction isogenic iPSC line
    Authors: X Ji, Q Tang, C Tang, Z Wu, L Ma, X Guo, G Cheng, Y Chen, T Yang, M Xiong, W Zhou
    Stem Cell Res, 2020-11-17;49(0):102089.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  48. Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem cells via Wnt receptor endocytosis
    Authors: F Pecori, Y Akimoto, H Hanamatsu, JI Furukawa, Y Shinohara, Y Ikehara, S Nishihara
    J. Cell. Sci., 2020-10-23;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  49. Four induced pluripotent stem cell lines (TRNDi021-C, TRNDi023-D, TRNDi024-D and TRNDi025-A) generated from fibroblasts of four healthy individuals
    Authors: X Xu, M Pradhan, M Xu, YS Cheng, J Beers, KL Linask, Y Lin, W Zheng, J Zou
    Stem Cell Res, 2020-10-01;49(0):102011.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  50. Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome
    Authors: SR Sripathy, Y Wang, RL Moses, A Fatemi, DA Batista, BJ Maher
    Stem Cell Res, 2020-09-17;48(0):102001.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  51. An interphase pool of KIF11 localizes at the basal bodies of primary cilia and a reduction in KIF11 expression alters cilia dynamics
    Authors: AA Zalenski, S Majumder, K De, M Venere
    Sci Rep, 2020-08-18;10(1):13946.
    Species: Human
    Sample Types: Complex Sample Type, Whole Tissue
    Applications: IHC
  52. Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
    Authors: L Muzio, R Sirtori, D Gornati, S Eleuteri, A Fossaghi, D Brancaccio, L Manzoni, L Ottoboni, L Feo, A Quattrini, E Mastrangel, L Sorrentino, E Scalone, G Comi, L Marinelli, N Riva, M Milani, P Seneci, G Martino
    Nat Commun, 2020-07-31;11(1):3848.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  53. The self-renewal dental pulp stem cell microtissues challenged by a toxic dental monomer
    Authors: G Kaufman, NM Kiburi, D Skrtic
    Biosci. Rep., 2020-06-26;40(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  54. Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
    Authors: M Mehdipour, C Skinner, N Wong, M Lieb, C Liu, J Etienne, C Kato, D Kiprov, MJ Conboy, IM Conboy
    Aging (Albany NY), 2020-05-30;12(10):8790-8819.
  55. Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer
    Authors: I Gomes, BP de Almeida, S Dâmaso, A Mansinho, I Correia, S Henriques, R Cruz-Duart, G Vilhais, P Félix, P Alves, P Corredeira, NL Barbosa-Mo, L Costa, S Casimiro
    Oncotarget, 2020-05-12;11(19):1714-1728.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  56. Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates
    Authors: N Micali, SK Kim, M Diaz-Busta, G Stein-O'Br, S Seo, JH Shin, BG Rash, S Ma, Y Wang, NA Olivares, JI Arellano, KR Maynard, EJ Fertig, AJ Cross, RW Bürli, NJ Brandon, DR Weinberger, JG Chenoweth, DJ Hoeppner, N Sestan, P Rakic, C Colantuoni, RD McKay
    Cell Rep, 2020-05-05;31(5):107599.
    Species: Human
    Sample Types:
    Applications: IF
  57. Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells
    Authors: R Kitajima, R Nakai, T Imamura, T Kameda, D Kozuka, H Hirai, H Ito, H Imai, M Imamura
    Stem Cell Res, 2020-02-28;44(0):101749.
    Species: Pan troglodytes (Chimpanzee)
    Sample Types: Whole Cells
    Applications: ICC
  58. An induced pluripotent stem cell line (TRNDi001-D) from a Niemann-Pick disease type C1 (NPC1) patient carrying a homozygous p. I1061T (c. 3182T>C) mutation in the NPC1 gene
    Authors: R Li, M Pradhan, M Xu, A Roeder, J Beers, J Zou, C Liu, FD Porter, W Zheng
    Stem Cell Res, 2020-02-19;44(0):101737.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  59. PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain
    Authors: L Su, X Lei, H Ma, C Feng, J Jiang, J Jiao
    Cell Death Differ., 2020-02-03;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  60. Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy
    Authors: H Hengel, C Bosso-Lefè, G Grady, E Szenker-Ra, H Li, S Pierce, É Lebigot, TT Tan, MY Eio, G Narayanan, KH Utami, M Yau, N Handal, W Deigendesc, R Keimer, HM Marzouqa, M Gunay-Aygu, MJ Muriello, H Verhelst, S Weckhuysen, S Mahida, S Naidu, TG Thomas, JY Lim, ES Tan, D Haye, MAAP Willemsen, R Oegema, WG Mitchell, TM Pierson, MV Andrews, MC Willing, LH Rodan, TS Barakat, M van Slegte, RH Gavrilova, D Martinelli, T Gilboa, AM Tamim, MO Hashem, MD AlSayed, MM Abdulrahim, M Al-Owain, A Awaji, AAH Mahmoud, EA Faqeih, AA Asmari, SM Algain, LA Jad, HM Aldhalaan, I Helbig, DA Koolen, A Riess, I Kraegeloh-, P Bauer, S Gulsuner, H Stamberger, AYJ Ng, S Tang, S Tohari, B Keren, LE Schultz-Ro, EW Klee, S Barresi, M Tartaglia, H Mor-Shaked, S Maddirevul, A Begtrup, A Telegrafi, R Pfundt, R Schüle, B Ciruna, C Bonnard, MA Pouladi, JC Stewart, A Claridge-C, DJ Lefeber, FS Alkuraya, AS Mathuru, B Venkatesh, JJ Barycki, MA Simpson, SS Jamuar, L Schöls, B Reversade
    Nat Commun, 2020-01-30;11(1):595.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  61. Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures
    Authors: T Hyvärinen, A Hyysalo, FE Kapucu, L Aarnos, A Vinogradov, SJ Eglen, L Ylä-Outine, S Narkilahti
    Sci Rep, 2019-11-20;9(1):17125.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  62. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of long QT syndrome type 1
    Authors: M Mura, F Bastaroli, M Corli, M Ginevrino, F Calabrò, M Boni, L Crotti, EM Valente, PJ Schwartz, M Gnecchi
    Stem Cell Res, 2019-11-20;42(0):101658.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  63. Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs
    Authors: E Grall, V Gourain, A Naïr, E Martin, MC Birling, JN Freund, I Duluc
    Cell Death Dis, 2019-10-24;10(11):812.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  64. Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
    Authors: A Stubb, C Guzmán, E Närvä, J Aaron, TL Chew, M Saari, M Miihkinen, G Jacquemet, J Ivaska
    Nat Commun, 2019-10-18;10(1):4756.
    Species: Human
    Sample Types: Whole Cells
    Applications: Western Blot
  65. ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation
    Authors: NM Peñaranda-, C Meijer, Y Liang, BM Dijkstra, R Aguirre-Ga, WFA den Dunnen, FAE Kruyt
    Cell Death Dis, 2019-09-18;10(10):690.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  66. An induced pluripotent stem cell line (TRNDi010-C) from a patient carrying a homozygous p.R401X mutation in the NGLY1 gene
    Authors: S Yang, YS Cheng, R Li, M Pradhan, J Hong, J Beers, J Zou, C Liu, M Might, S Rodems, W Zheng
    Stem Cell Res, 2019-07-09;39(0):101496.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  67. Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations
    Authors: J Yao, X Wu, D Zhang, L Wang, L Zhang, EX Reynolds, C Hernandez, KI Boström, Y Yao
    J. Clin. Invest., 2019-06-24;130(0):.
    Species: Human, Mouse
    Sample Types: Tissue Homogenates, Whole Cells
    Applications: ChIP, ChIP-Seq, Flow Cytometry, ICC, Western Blot
  68. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
    Authors: M Huang, J Tailor, Q Zhen, AH Gillmor, ML Miller, H Weishaupt, J Chen, T Zheng, EK Nash, LK McHenry, Z An, F Ye, Y Takashima, J Clarke, H Ayetey, FMG Cavalli, B Luu, BS Moriarity, S Ilkhanizad, L Chavez, C Yu, KM Kurian, T Magnaldo, N Sevenet, P Koch, SM Pollard, P Dirks, MP Snyder, DA Largaespad, YJ Cho, JJ Phillips, FJ Swartling, AS Morrissy, M Kool, SM Pfister, MD Taylor, A Smith, WA Weiss
    Cell Stem Cell, 2019-06-13;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  69. Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner
    Authors: L Zurkirchen, S Varum, S Giger, A Klug, J Häusel, R Bossart, M Zemke, C Cantù, ZK Atak, N Zamboni, K Basler, L Sommer
    Nat Commun, 2019-05-16;10(1):2192.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  70. An induced pluripotent stem cell line (TRNDi009-C) from a Niemann-Pick disease type A patient carrying a heterozygous p.L302P (c.905 T>C) mutation in the SMPD1 gene
    Authors: A Baskfield, R Li, J Beers, J Zou, C Liu, W Zheng
    Stem Cell Res, 2019-05-15;38(0):101461.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  71. The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line
    Authors: S Howden, H Hosseini F, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman
    Stem Cell Res, 2019-05-04;38(0):101453.
    Species: Human
    Sample Types: Whole Cells
  72. CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons
    Authors: C Calatayud, G Carola, I Fernández-, M Valtorta, S Jiménez-De, M Díaz, J Soriano-Fr, G Cappellett, J García-San, Á Raya, A Consiglio
    Sci Rep, 2019-05-02;9(1):6811.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  73. Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene
    Authors: J Hong, M Xu, R Li, YS Cheng, J Kouznetsov, J Beers, C Liu, J Zou, W Zheng
    Stem Cell Res, 2019-04-25;37(0):101451.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  74. User-defined morphogen patterning for directing human cell fate stratification
    Authors: MC Regier, JJ Tokar, JW Warrick, L Pabon, E Berthier, DJ Beebe, KR Stevens
    Sci Rep, 2019-04-23;9(1):6433.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  75. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi005-A from a patient carrying the KCNQ1-R190W mutation
    Authors: M Mura, YK Lee, F Pisano, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
    Stem Cell Res, 2019-04-13;37(0):101437.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  76. Generation of an induced pluripotent stem cell line (TRNDi004-I) from a Niemann-Pick disease type B patient carrying a heterozygous mutation of p.L43_A44delLA in the SMPD1 gene
    Authors: A Baskfield, R Li, J Beers, J Zou, C Liu, W Zheng
    Stem Cell Res, 2019-04-12;37(0):101436.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  77. A human induced pluripotent stem cell line (TRNDi007-B) from an infantile onset Pompe patient carrying p.R854X mutation in the GAA gene
    Authors: YS Cheng, R Li, A Baskfield, J Beers, J Zou, C Liu, W Zheng
    Stem Cell Res, 2019-04-11;37(0):101435.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  78. Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness
    Authors: SFB Fadhlullah, NBA Halim, JYT Yeo, RLY Ho, P Um, BT Ang, C Tang, WH Ng, DM Virshup, IAW Ho
    Oncogene, 2019-04-09;38(27):5367-5380.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  79. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi004-A from a carrier of the KCNQ1-R594Q mutation
    Authors: M Mura, YK Lee, F Pisano, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
    Stem Cell Res, 2019-03-27;37(0):101431.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  80. An induced pluripotent stem cell line (TRNDi006-A) from a MPS IIIB patient carrying homozygous mutation of p.Glu153Lys in the NAGLU gene
    Authors: W Huang, M Xu, R Li, A Baskfield, J Kouznetsov, J Beers, J Zou, C Liu, W Zheng
    Stem Cell Res, 2019-03-23;37(0):101427.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  81. SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma
    Authors: M Sherman-Sa, H Onallah, A Holth, R Reich, B Davidson
    Gynecol. Oncol., 2019-03-21;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  82. A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma
    Authors: BW Stringer, BW Day, RCJ D'Souza, PR Jamieson, KS Ensbey, ZC Bruce, YC Lim, K Goasdoué, C Offenhäuse, S Akgül, S Allan, T Robertson, P Lucas, G Tollesson, S Campbell, C Winter, H Do, A Dobrovic, PL Inglis, RL Jeffree, TG Johns, AW Boyd
    Sci Rep, 2019-03-20;9(1):4902.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  83. Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death
    Authors: MA Ajmone-Cat, A Onori, C Toselli, E Stronati, M Morlando, I Bozzoni, E Monni, Z Kokaia, G Lupo, L Minghetti, S Biagioni, E Cacci
    Sci Rep, 2019-03-14;9(1):4572.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  84. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi007-A from a Long QT Syndrome type 1 patient carrier of two common variants in the NOS1AP gene
    Authors: M Mura, F Pisano, M Stefanello, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, PA Brink, M Gnecchi
    Stem Cell Res, 2019-03-06;36(0):101416.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  85. Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids
    Authors: H Kim, HJ Park, H Choi, Y Chang, H Park, J Shin, J Kim, CJ Lengner, YK Lee, J Kim
    Stem Cell Reports, 2019-02-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  86. Generation of an induced pluripotent stem cell line (TRNDi005-A) from a Mucopolysaccharidosis Type IVA (MPS IVA) patient carrying compound heterozygous p.R61W and p.WT405del mutations in the GALNS gene
    Authors: R Li, A Baskfield, J Beers, J Zou, C Liu, CJ Alméciga-D, W Zheng
    Stem Cell Res, 2019-02-15;36(0):101408.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  87. Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy
    Authors: T Klein, K Klug, L Henkel, CK Kwok, F Edenhofer, E Klopocki, I Kurth, N Üçeyler
    Stem Cell Res, 2019-02-02;35(0):101396.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  88. The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer
    Authors: S Melissarid, E Wiechec, M Magan, MV Jain, MK Chung, L Farnebo, K Roberg
    Cancer Cell Int., 2019-01-14;19(0):16.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  89. Single-cell transcriptomic analysis of mouse neocortical development
    Authors: L Loo, JM Simon, L Xing, ES McCoy, JK Niehaus, J Guo, ES Anton, MJ Zylka
    Nat Commun, 2019-01-11;10(1):134.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  90. Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene
    Authors: R Li, A Baskfield, Y Lin, J Beers, J Zou, C Liu, F Jaffré, AE Roberts, EA Ottinger, MI Kontaridis, W Zheng
    Stem Cell Res, 2018-12-26;34(0):101374.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  91. Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene
    Authors: R Li, M Pradhan, M Xu, A Baskfield, A Farkhondeh, YS Cheng, J Beers, J Zou, C Liu, M Might, S Rodems, W Zheng
    Stem Cell Res, 2018-12-05;34(0):101362.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  92. Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation
    Authors: CP Cui, Y Zhang, C Wang, F Yuan, H Li, Y Yao, Y Chen, C Li, W Wei, CH Liu, F He, Y Liu, L Zhang
    Nat Commun, 2018-11-07;9(1):4648.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  93. Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient
    Authors: S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, D Bachiller
    Stem Cell Res, 2018-11-01;33(0):180-184.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  94. Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
    Authors: M Jeong, M O'Reilly, NK Kirkwood, J Al-Aama, M Lako, CJ Kros, L Armstrong
    Cell Death Dis, 2018-09-11;9(9):922.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  95. Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata)
    Authors: R Nakai, M Ohnuki, K Kuroki, H Ito, H Hirai, R Kitajima, T Fujimoto, M Nakagawa, W Enard, M Imamura
    Sci Rep, 2018-08-15;8(1):12187.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: ICC
  96. The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo
    Authors: SU Vay, LJ Flitsch, M Rabenstein, R Rogall, S Blaschke, J Kleinhaus, N Reinert, A Bach, GR Fink, M Schroeter, MA Rueger
    J Neuroinflammation, 2018-08-13;15(1):226.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  97. Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708?G?>?C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene
    Authors: T Klein, K Günther, CK Kwok, F Edenhofer, N Üçeyler
    Stem Cell Res, 2018-08-10;31(0):222-226.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  98. Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel
    Authors: X Gao, JJ Yourick, RL Sprando
    Stem Cell Res, 2018-07-27;31(0):193-196.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  99. Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation
    Authors: S Kwak, TW Kim, BH Kang, JH Kim, JS Lee, HT Lee, IY Hwang, J Shin, JH Lee, EJ Cho, HD Youn
    Nucleic Acids Res., 2018-07-27;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  100. Differential response in novel stem cell niches of the brain following cervical spinal cord injury and traumatic brain injury
    Authors: A Falnikar, J Stratton, R Lin, CE Andrews, A Tyburski, VA Trovillion, C Gottschalk, B Ghosh, L Iacovitti, MB Elliott, AC Lepore
    J. Neurotrauma, 2018-06-07;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  101. The non-canonical Wnt-PCP pathway shapes the caudal neural plate
    Authors: B López-Esco, JM Caro-Vega, DS Vijayragha, TF Plageman, JA Sanchez-Al, RC Moreno, D Savery, J Márquez-Ri, LA Davidson, P Ybot-Gonzá
    Development, 2018-05-08;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  102. INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice
    Authors: O Le, L Palacio, G Bernier, I Batinic-Ha, G Hickson, C Beauséjour
    Stem Cell Reports, 2018-04-26;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  103. TFAP2C regulates transcription in human naive pluripotency by opening enhancers
    Authors: WA Pastor, W Liu, D Chen, J Ho, R Kim, TJ Hunt, A Lukianchik, X Liu, JM Polo, SE Jacobsen, AT Clark
    Nat. Cell Biol., 2018-04-25;20(5):553-564.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  104. Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease
    Authors: JY Lee, SH Han, MH Park, B Baek, IS Song, MK Choi, Y Takuwa, H Ryu, SH Kim, X He, EH Schuchman, JS Bae, HK Jin
    Nat Commun, 2018-04-16;9(1):1479.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  105. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi002-A from a patient affected by the Jervell and Lange-Nielsen syndrome and carrier of two compound heterozygous mutations on the KCNQ1 gene
    Authors: M Mura, YK Lee, M Ginevrino, R Zappatore, F Pisano, M Boni, F Dagradi, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
    Stem Cell Res, 2018-04-07;29(0):157-161.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  106. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi003-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1
    Authors: M Mura, M Ginevrino, R Zappatore, F Pisano, M Boni, S Castellett, L Crotti, EM Valente, PJ Schwartz, M Gnecchi
    Stem Cell Res, 2018-04-06;29(0):170-173.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  107. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation
    Authors: NS Corsini, AM Peer, P Moeseneder, M Roiuk, TR Burkard, HC Theussl, I Moll, JA Knoblich
    Cell Stem Cell, 2018-04-05;22(4):543-558.e12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  108. Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity
    Authors: D Poppe, J Doerr, M Schneider, R Wilkens, JA Steinbeck, J Ladewig, A Tam, DE Paschon, PD Gregory, A Reik, CE Müller, P Koch, O Brüstle
    Stem Cells Transl Med, 2018-03-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  109. Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas
    Authors: C Aaberg-Jes, MD Sørensen, ALSA Matos, JM Moreira, N Brünner, A Knudsen, BW Kristensen
    BMC Cancer, 2018-03-09;18(1):270.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  110. Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs
    Authors: M Chen, SH Laursen, M Habekost, CH Knudsen, SH Buchholdt, J Huang, F Xu, X Liu, L Bolund, Y Luo, P Nissen, F Febbraro, M Denham
    Front Cell Dev Biol, 2018-02-06;6(0):5.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  111. Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein
    Authors: G V?fély, T Berecz, E Szabó, K Szebényi, E Hathy, TI Orbán, B Sarkadi, L Homolya, MC Marchetto, JM Réthelyi, Á Apáti
    Mol. Cell. Neurosci., 2018-02-06;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  112. Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
    Authors: A Yachie-Kin, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, PW Zandstra
    Mol. Syst. Biol., 2018-01-29;14(1):e7952.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  113. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
    Authors: M Naumann, A Pal, A Goswami, X Lojewski, J Japtok, A Vehlow, M Naujock, R Günther, M Jin, N Stanslowsk, P Reinhardt, J Sternecker, M Frickenhau, F Pan-Montoj, E Storkebaum, I Poser, A Freischmid, JH Weishaupt, K Holzmann, D Troost, AC Ludolph, TM Boeckers, S Liebau, S Petri, N Cordes, AA Hyman, F Wegner, SW Grill, J Weis, A Storch, A Hermann
    Nat Commun, 2018-01-23;9(1):335.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  114. FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury
    Authors: A Alastrue-A, FJ Rodriguez-, EL Mocholi, F De Giorgio, S Erceg, V Moreno-Man
    Int J Mol Sci, 2018-01-09;19(1):.
    Species: Rat
    Sample Types: Cell Lysates
    Applications: Western Blot
  115. Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson's disease, as an anti-cancer stem cell drug
    Authors: M Okada, H Takeda, H Sakaki, K Kuramoto, S Suzuki, T Sanomachi, K Togashi, S Seino, C Kitanaka
    Oncotarget, 2017-10-24;8(55):94872-94882.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  116. FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1
    Authors: K Hirano, M Namihira
    FEBS Open Bio, 2017-10-17;7(12):1932-1942.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  117. Laminin ?5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro
    Authors: A Hyysalo, M Ristola, ME Mäkinen, S Häyrynen, M Nykter, S Narkilahti
    Stem Cell Res, 2017-09-12;24(0):118-127.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  118. Generation of an ASGR1 homozygous mutant human embryonic stem cell line WAe001-A-6 using CRISPR/Cas9
    Authors: Y Xu, Y Wu, D Guo, G Gao, K Lai, F Yang, K Wang, H Wu, L Lai, J Li, K Xu, YX Li
    Stem Cell Res, 2017-05-19;22(0):29-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  119. Nicotinamide metabolism regulates glioblastoma stem cell maintenance
    Authors: J Jung, LJY Kim, X Wang, Q Wu, T Sanvoranar, CG Hubert, BC Prager, LC Wallace, X Jin, SC Mack, JN Rich
    JCI Insight, 2017-05-18;2(10):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  120. HIF1? regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia
    Authors: P Wang, C Lan, S Xiong, X Zhao, Y Shan, R Hu, W Wan, S Yu, B Liao, G Li, J Wang, D Zou, B Chen, H Feng, N Wu
    Oncotarget, 2017-04-25;8(17):28074-28092.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  121. Spatial development of gingival fibroblasts and dental pulp cells: Effect of extracellular matrix
    Authors: G Kaufman, D Skrtic
    Tissue Cell, 2017-04-10;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  122. Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
    Authors: X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJ Kim, BC Prager, WA Flavahan, X Liu, M Singer, CG Hubert, TE Miller, W Zhou, Z Huang, X Fang, A Regev, ML Suvà, TH Hwang, JW Locasale, S Bao, JN Rich
    Nat. Neurosci, 2017-03-27;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  123. Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa
    Authors: TP Sharma, LA Wiley, SS Whitmore, KR Anfinson, CM Cranston, DJ Oppedal, HT Daggett, RF Mullins, BA Tucker, EM Stone
    Stem Cell Res, 2017-03-18;21(0):58-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  124. Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo
    Authors: SS Jensen, SA Petterson, B Halle, C Aaberg-Jes, BW Kristensen
    BMC Cancer, 2017-03-07;17(1):178.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  125. A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity
    Authors: G Riddick, S Kotliarova, V Rodriguez, HS Kim, A Linkous, AJ Storaska, S Ahn, J Walling, G Belova, HA Fine
    Sci Rep, 2017-03-03;7(0):43605.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  126. A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases
    Authors: I Karakikes, V Termglinch, DA Cepeda, J Lee, S Diecke, A Hendel, I Itzhaki, M Ameen, R Shrestha, H Wu, N Ma, NY Shao, T Seeger, NA Woo, KD Wilson, E Matsa, MH Porteus, V Sebastiano, JC Wu
    Circ. Res, 2017-02-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  127. Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma
    Authors: R Bayat Mokh, N Baluch, M Ka Hon Tsu, S Kumar, T S Homayoun, K Aitken, B Das, S Baruchel, H Yeger
    BMC Cancer, 2017-02-24;17(1):156.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  128. Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding
    Authors: S Falk, S Bugeon, J Ninkovic, GA Pilz, MP Postiglion, H Cremer, JA Knoblich, M Götz
    Neuron, 2017-02-22;93(4):777-791.e3.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  129. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells
    Authors: T Yamashita, Y Miyamoto, Y Bando, T Ono, S Kobayashi, A Doi, T Araki, Y Kato, T Shirakawa, Y Suzuki, J Yamauchi, S Yoshida, N Sato
    PLoS ONE, 2017-02-13;12(2):e0171947.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  130. Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
    Authors: AG Alvarado, PS Thiagaraja, EE Mulkearns-, DJ Silver, JS Hale, TJ Alban, SM Turaga, A Jarrar, O Reizes, MS Longworth, MA Vogelbaum, JD Lathia
    Cell Stem Cell, 2017-01-12;20(4):450-461.e4.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  131. RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells
    Authors: HO King, T Brend, HL Payne, A Wright, TA Ward, K Patel, T Egnuni, LF Stead, A Patel, H Wurdak, SC Short
    Stem Cell Reports, 2017-01-10;8(1):125-139.
    Species: Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  132. SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis
    PLoS Biol., 2016-11-23;14(11):e1002581.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  133. ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA
    Oncogene, 2016-09-19;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  134. Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9
    Stem Cell Res, 2016-09-16;17(2):430-432.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  135. Generation of a TLE3 heterozygous knockout human embryonic stem cell line using CRISPR-Cas9
    Stem Cell Res, 2016-09-15;17(2):441-443.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  136. Enhancing the Three-Dimensional Structure of Adherent Gingival Fibroblasts and Spheroids via a Fibrous Protein-Based Hydrogel Cover
    Cells Tissues Organs (Print), 2016-08-30;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  137. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A
    Stem Cells Transl Med, 2016-08-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  138. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness
    Sci Rep, 2016-07-29;6(0):30742.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  139. Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells
    Authors: Annabelle Congras
    Sci Rep, 2016-06-01;6(0):27059.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: IHC
  140. Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion
    Stem Cells, 2016-05-27;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  141. Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype
    PLoS ONE, 2016-05-12;11(5):e0155106.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  142. Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiation.
    Authors: Garriock R, Chalamalasetty R, Kennedy M, Canizales L, Lewandoski M, Yamaguchi T
    Development, 2015-05-01;142(9):1628-38.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  143. SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
    Authors: Kim, Dohoon, Fiske, Brian P, Birsoy, Kivanc, Freinkman, Elizavet, Kami, Kenjiro, Possemato, Richard, Chudnovsky, Yakov, Pacold, Michael, Chen, Walter W, Cantor, Jason R, Shelton, Laura M, Gui, Dan Y, Kwon, Manjae, Ramkissoon, Shakti H, Ligon, Keith L, Kang, Seong Wo, Snuderl, Matija, Vander Heiden, Matthew, Sabatini, David M
    Nature, 2015-04-08;520(7547):363-7.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  144. Isolation of cancer stem cells from three human glioblastoma cell lines: characterization of two selected clones.
    Authors: Iacopino F, Angelucci C, Piacentini R, Biamonte F, Mangiola A, Maira G, Grassi C, Sica G
    PLoS ONE, 2014-08-14;9(8):e105166.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  145. Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency.
    Authors: Onishi K, Tonge P, Nagy A, Zandstra P
    Stem Cell Reports, 2014-06-06;3(1):156-68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  146. Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.
    Authors: Yan K, Wu Q, Yan D, Lee C, Rahim N, Tritschler I, DeVecchio J, Kalady M, Hjelmeland A, Rich J
    Genes Dev, 2014-05-01;28(10):1085-100.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  147. Fluoxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro.
    Authors: Sousa-Ferreira L, Aveleira C, Botelho M, Alvaro A, Pereira de Almeida L, Cavadas C
    PLoS ONE, 2014-03-05;9(3):e88917.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  148. A single-cell and feeder-free culture system for monkey embryonic stem cells.
    Authors: Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, Kato H, Torii R, Sato N
    PLoS ONE, 2014-02-05;9(2):e88346.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: ICC
  149. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.
    Authors: Miao, H, Gale, N W, Guo, H, Qian, J, Petty, A, Kaspar, J, Murphy, A J, Valenzuela, D M, Yancopoulos, G, Hambardzumyan, D, Lathia, J D, Rich, J N, Lee, J, Wang, B
    Oncogene, 2014-02-03;34(5):558-67.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  150. Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape.
    Authors: Sherwood, Richard, Hashimoto, Tatsunor, O'Donnell, Charles, Lewis, Sophia, Barkal, Amira A, van Hoff, John Pet, Karun, Vivek, Jaakkola, Tommi, Gifford, David K
    Nat Biotechnol, 2014-01-19;32(2):171-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  151. Chondroitin sulfate is indispensable for pluripotency and differentiation of mouse embryonic stem cells.
    Authors: Izumikawa, Tomomi, Sato, Ban, Kitagawa, Hiroshi
    Sci Rep, 2014-01-15;4(0):3701.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC, Western Blot
  152. Zrf1 is required to establish and maintain neural progenitor identity.
    Authors: Aloia L, Di Stefano B, Sessa A, Morey L, Santanach A, Gutierrez A, Cozzuto L, Benitah S, Graf T, Broccoli V, Di Croce L
    Genes Dev, 2014-01-15;28(2):182-97.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  153. Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex.
    Authors: Minamide, Ryohei, Fujiwara, Kazushir, Hasegawa, Koichi, Yoshikawa, Kazuaki
    PLoS ONE, 2014-01-02;9(1):e84460.
    Species: Mouse
    Sample Types: Tissue Homogenates, Whole Cells, Whole Tissue
    Applications: ICC, IHC-P, Western Blot
  154. The subventricular zone is able to respond to a demyelinating lesion after localized radiation.
    Authors: Capilla-Gonzalez V, Guerrero-Cazares H, Bonsu J, Gonzalez-Perez O, Achanta P, Wong J, Garcia-Verdugo J, Quinones-Hinojosa A
    Stem Cells, 2014-01-01;32(1):59-69.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  155. Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4.
    Authors: Volonte A, Di Tomaso T, Spinelli M, Todaro M, Sanvito F, Albarello L, Bissolati M, Ghirardelli L, Orsenigo E, Ferrone S, Doglioni C, Stassi G, Dellabona P, Staudacher C, Parmiani G, Maccalli C
    J Immunol, 2013-11-25;192(1):523-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  156. Oct4 is required ~E7.5 for proliferation in the primitive streak.
    Authors: DeVeale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, Onishi K, Tomilin A, Pevny L, Zandstra P, Nagy A, van der Kooy D
    PLoS Genet, 2013-11-14;9(11):e1003957.
    Species: Mouse
    Sample Types: Embryo
    Applications: IHC-P
  157. Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb.
    Authors: Li, Tan, Pan, Yung-Wei, Wang, Wenbin, Abel, Glen, Zou, Junhui, Xu, Lihong, Storm, Daniel R, Xia, Zhengui
    PLoS ONE, 2013-04-22;8(4):e61948.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  158. Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.
    Authors: Najm, Fadi J, Lager, Angela M, Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V, Factor, Daniel C, Karl, Robert T, Maeda, Tadao, Miller, Robert H, Tesar, Paul J
    Nat Biotechnol, 2013-04-14;31(5):426-33.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  159. Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus.
    Authors: Haan, Niels, Goodman, Timothy, Najdi-Samiei, Alaleh, Stratford, Christin, Rice, Ritva, El Agha, Elie, Bellusci, Saverio, Hajihosseini, Mohammad
    J Neurosci, 2013-04-03;33(14):6170-80.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  160. Embryonic stem cell-based modeling of tau pathology in human neurons.
    Authors: Mertens J, Stuber K, Poppe D, Doerr J, Ladewig J, Brustle O, Koch P
    Am J Pathol, 2013-03-13;182(5):1769-79.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  161. Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium.
    Authors: Hayashi, Ryuhei, Ishikawa, Yuki, Ito, Miyuki, Kageyama, Tomofumi, Takashiba, Kuniko, Fujioka, Tsuyoshi, Tsujikawa, Motokazu, Miyoshi, Hiroyuki, Yamato, Masayuki, Nakamura, Yukio, Nishida, Kohji
    PLoS ONE, 2012-09-24;7(9):e45435.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  162. REST regulates oncogenic properties of glioblastoma stem cells.
    Authors: Kamal MM, Sathyan P, Singh SK, Zinn PO, Marisetty AL, Liang S, Gumin J, El-Mesallamy HO, Suki D, Colman H, Fuller GN, Lang FF, Majumder S
    Stem Cells, 2012-03-01;30(3):405-14.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  163. Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects.
    Authors: Mahar I, Tan S, Davoli MA, Dominguez-Lopez S, Qiang C, Rachalski A, Turecki G, Mechawar N
    PLoS ONE, 2011-10-19;6(10):e26610.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  164. Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells.
    Authors: Lathia JD, Gallagher J, Myers JT
    PLoS ONE, 2011-09-22;6(9):e24807.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  165. Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel.
    Authors: Hibino N, Villalona G, Pietris N
    FASEB J., 2011-05-12;25(8):2731-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  166. Human haploid cells differentiated from meiotic competent clonal germ cell lines that originated from embryonic stem cells.
    Authors: West FD, Mumaw JL, Gallegos-Cardenas A, Young A, Stice SL
    Stem Cells Dev., 2010-12-02;20(6):1079-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  167. Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells.
    Authors: Kambal A, Mitchell G, Cary W, Gruenloh W, Jung Y, Kalomoiris S, Nacey C, McGee J, Lindsey M, Fury B, Bauer G, Nolta JA, Anderson JS
    Mol. Ther., 2010-11-30;19(3):584-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  168. Paternal recognition of adult offspring mediated by newly generated CNS neurons.
    Authors: Mak GK, Weiss S
    Nat. Neurosci., 2010-05-09;13(6):753-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  169. Noninvasive imaging of endogenous neural stem cell mobilization in vivo using positron emission tomography.
    Authors: Rueger MA, Backes H, Walberer M, Neumaier B, Ullrich R, Simard ML, Emig B, Fink GR, Hoehn M, Graf R, Schroeter M
    J. Neurosci., 2010-05-05;30(18):6454-60.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  170. Diagnostic utility of novel stem cell markers SALL4, OCT4, NANOG, SOX2, UTF1, and TCL1 in primary mediastinal germ cell tumors.
    Authors: Liu A, Cheng L, Du J, Peng Y, Allan RW, Wei L, Li J, Cao D
    Am. J. Surg. Pathol., 2010-05-01;34(5):697-706.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  171. Epigenetic changes to human umbilical cord blood cells cultured with three proteins indicate partial reprogramming to a pluripotent state.
    Authors: Wong CJ, Casper RF, Rogers IM
    Exp. Cell Res., 2010-01-22;316(6):927-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  172. The intracellular distribution of the ES cell totipotent markers OCT4 and Sox2 in adult stem cells differs dramatically according to commercial antibody used.
    J. Cell. Biochem., 2009-04-01;106(5):867-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  173. Efficient Serum-Free Derivation of Oligodendrocyte Precursors from Neural Stem Cell-Enriched Cultures.
    Authors: Rao RC, Boyd J, Padmanabhan R, Chenoweth JG, McKay RD
    Stem Cells, 2009-01-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  174. Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
    Authors: Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, Ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP
    J. Neurosci., 2008-12-17;28(51):13978-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  175. Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells.
    Authors: Neganova I, Zhang X, Atkinson S, Lako M
    Oncogene, 2008-09-22;28(1):20-30.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  176. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
    Authors: Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL
    Nat. Cell Biol., 2008-06-22;10(7):837-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  177. Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria.
    Authors: Gunther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K
    Oncogene, 2007-11-26;27(20):2897-909.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry, ICC
  178. Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1.
    Authors: Hattori Y, Ohta S, Hamada K, Yamada-Okabe H, Kanemura Y, Matsuzaki Y, Okano H, Kawakami Y, Toda M
    Biochem. Biophys. Res. Commun., 2007-10-15;364(4):737-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  179. Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy.
    Authors: Schmitz M, Temme A, Senner V, Ebner R, Schwind S, Stevanovic S, Wehner R, Schackert G, Schackert HK, Fussel M, Bachmann M, Rieber EP, Weigle B
    Br. J. Cancer, 2007-03-20;96(8):1293-301.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells, Whole Tissue
    Applications: ICC, IHC-P, Western Blot
  180. Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage.
    Authors: Pankratz MT, Li XJ, Lavaute TM, Lyons EA, Chen X, Zhang SC
    Stem Cells, 2007-03-01;25(6):1511-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  181. Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue.
    Authors: Shin S, Sun Y, Liu Y, Khaner H, Svant S, Cai J, Xu QX, Davidson BP, Stice SL, Smith AK, Goldman SA, Reubinoff BE, Zhan M, Rao MS, Chesnut JD
    Stem Cells, 2007-02-01;25(5):1298-306.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  182. Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats.
    Authors: Kobayashi T, Ahlenius H, Thored P, Kobayashi R, Kokaia Z, Lindvall O
    Stroke, 2006-07-27;37(9):2361-7.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC

FAQs

  1. What is the light chain of Human/Mouse/Rat SOX2 Antibody, Catalog #s MAB2018, MAB2018R and IC2018?

    • Catalog #s MAB2018, MAB2018R and IC2018 all have a kappa light chain.

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Human/Mouse/Rat SOX2 Antibody
By Anonymous on 08/06/2021
Application: ICC/IF Sample Tested: glioblastoma cells Species: Human

On the photo SOX2 is red, nuclear DAPI is blue.


Human/Mouse/Rat SOX2 Antibody
By Shuba Krishnan on 10/18/2018
Application: ICC/IF Sample Tested: iPS2 human induced pluripotent stem cells Species: Human

Cells: human induced pluripotent stem cells
Primary antibody: anti-human SOX2 (1:200), O/N incubation at 4 degrees
Secondary antibody: anti-mouse AF488


Human/Mouse/Rat SOX2 Antibody
By Anonymous on 02/16/2017
Application: IHC Sample Tested: Brain (forebrain) Species: Mouse

Red: sox2. Green: ki67. Blue: DAPI. Postnatal day 7 sub-ventricular zone. 2% PFA fixed. Heat-mediated antigen retrieval. Blocked with 10% donkey serum, 0.5% Triton in PBS for 1h. Dilution 1:100.


Human/Mouse/Rat SOX2 Antibody
By Anonymous on 02/03/2017
Application: ICC/IF Sample Tested: Neural progenitor cells Species: Human

Human/Mouse SOX2 Antibody
By Anonymous on 12/15/2016
Application: ICC/IF Sample Tested: Induced pluripotent stem cells Species: Human

I used this antibody to test Sox2 expression in iPS cells derived from fibroblasts of Sanfilippo syndrome C patients.


Human/Mouse SOX2 Antibody
By Anonymous on 10/26/2015
Application: WB Sample Tested: Human cells Species: Human

Specificity: Specific
Sensitivity: Sensitive
Buffer: 5% BSA in TBST
Dilution: 1/1000


Human/Mouse SOX2 Antibody
By Anonymous on 10/26/2015
Application: ICC/IF Sample Tested: human NSC Species: Human

Specificity: Specific
Sensitivity: Reasonably sensitive
Buffer: 1% BSA + 0.3% Triton X-100 in PBS
Dilution: 1/100


Human/Mouse SOX2 Antibody
By Anonymous on 10/26/2015
Application: ICC/IF Sample Tested: human fibroblast and neural stem cells Species: Human

Specificity: Specific
Sensitivity: Reasonably sensitive
Buffer: 1% BSA + 0.3% Triton X-100 in PBS
Dilution: 1/100