Human NKG2C/CD159c PE-conjugated Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
Detection of NKG2C/CD159c in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A) and either (A) Mouse Anti-Human NKG2C/CD159c PE-conjugated Monoclonal Antibody (Catalog # FAB138P) or (B) Mouse IgG1Phycoerythrin Isotype Control (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: NKG2C/CD159c
Human NKG2C (NK cell Group 2 isoform C; Killer cell lectin-like receptor subfamily C, member 2) is a member of the C-type lectin-like superfamily of proteins. Natural killer (NK) receptors are expressed in both NK cells and cytotoxic CD8+ T cells and have both activating and inhibitory members (1-3). Regulation of the balance between the activating and inhibitory receptors is important and lack of such regulation has been implicated in autoimmunity (4). The NKG2 family includes seven receptors: NKG2A, -B, -C, -D, -E, -F, and -H, which is the longer isoform of NKG2E. Except for NKG2D and NKG2F, the NKG2 family members form heterodimers with CD94 (5, 6). NKG2C interacts with the adapter molecule DAP12 and acts as activating receptor when heterodimerized with CD94 (7). Human NKG2C is synthesized as a 231 amino acid (aa) protein that includes a 70 aa cytoplasmic domain, a 23 aa transmembrane segment, and a 138 aa extracellular domain (ECD). Within the ECD, human NKG2C shares 40% sequence identity with mouse NKG2C. NKG2C-CD94 heterodimers bind to the widely expressed nonclassical MHC-I molecule, HLA-E (Qa-1b in mouse), which presents a peptide derived from the signal peptide of classical MHC-I molecules (8, 9). Triggering the NKG2C-CD94 complex may activate the cytolytic activity and cytokine production of NK and CD8+ T cells (8, 10). Human cytomegalovirus (HCMV) infection promotes the differentiation and expansion of NKG2C+ NK cell subsets, possibly involving a cognate interaction of CD94/NKG2C with ligand(s) displayed by HCMV‑infected cells (11, 12).
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- Lanier, L.L. (1998) Immunity 8:693.
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- Kaiser B.K. et al. (2005) J Immunol 174:2878.
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- Pupuleku A. et al. (2017) Front Immunol. 8:1317.
- Hammer Q. et al. (2018) Nat Immunol. 19:453.
Product Datasheets
Citations for Human NKG2C/CD159c PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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PGE2 expression by HPV6/11-induced respiratory papillomas blocks NK cell activation in patients with recurrent respiratory papillomatosis
Authors: M Israr, F Lam, J DeVoti, EM Mace, C Papayannak, A Abramson, BM Steinberg, VR Bonagura
European Journal of Immunology, 2023-01-31;0(0):e2250036.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency
Authors: S Wahlen, F Matthijsse, W Van Loocke, S Taveirne, L Kiekens, E Persyn, E Van Ammel, Z De Vos, S De Munter, P Matthys, F Van Nieuwe, T Taghon, B Vandekerck, P Van Vlierb, G Leclercq
Elife, 2022-07-06;11(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Increased Susceptibility of the CD57- NK Cells Expressing KIR2DL2/3 and NKG2C to iCasp9 Gene Retroviral Transduction and the Relationships with Proliferative Potential, Activation Degree, and Death Induction Response
Authors: AI Palamarchu, NA Alekseeva, MA Streltsova, MO Ustiuzhani, PA Kobyzeva, SA Kust, MV Grechikhin, AA Boyko, OA Shustova, AM Sapozhniko, EI Kovalenko
International Journal of Molecular Sciences, 2021-12-11;22(24):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults
Authors: VA Vieira, E Adland, DFG Malone, MP Martin, A Groll, MA Ansari, MC Garcia-Gue, MC Puertas, M Muenchhoff, CF Guash, C Brander, J Martinez-P, A Bamford, G Tudor-Will, T Ndung'u, BD Walker, V Ramsuran, J Frater, P Jooste, D Peppa, M Carrington, PJR Goulder
PloS Pathogens, 2021-11-18;17(11):e1010090.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Characterization of Adaptive-like gammadelta T Cells in Ugandan Infants during Primary Cytomegalovirus Infection
Authors: J Tuengel, S Ranchal, A Maslova, G Aulakh, M Papadopoul, S Drissler, B Cai, C Mohsenzade, H Soudeyns, S Mostafavi, P van den El, D Vermijlen, L Cook, S Gantt
Viruses, 2021-10-03;13(10):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
Authors: KV Woan, H Kim, R Bjordahl, ZB Davis, S Gaidarova, J Goulding, B Hancock, S Mahmood, R Abujarour, H Wang, K Tuininga, B Zhang, CY Wu, B Kodal, M Khaw, L Bendzick, P Rogers, MQ Ge, G Bonello, M Meza, M Felices, J Huffman, T Dailey, TT Lee, B Walcheck, KJ Malmberg, BR Blazar, YT Bryceson, B Valamehr, JS Miller, F Cichocki
Cell Stem Cell, 2021-09-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization
Authors: MA Streltsova, MO Ustiuzhani, EV Barsov, SA Kust, RA Velichinsk, EI Kovalenko
Biomedicines, 2021-06-09;9(6):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
IL-18 Responsiveness Defines Limitations in Immune Help for Specialized FcR&gamma- NK Cells
Authors: RR Anderko, CR Rinaldo, RB Mailliard
J Immunol, 2020-11-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma
Authors: HC Tseng, W Xiong, S Badeti, Y Yang, M Ma, T Liu, CA Ramos, G Dotti, L Fritzky, JG Jiang, Q Yi, J Guarrera, WX Zong, C Liu, D Liu
Nat Commun, 2020-09-23;11(1):4810.
Species: Human
Sample Types: Whole Cells, Whole Tissue
Applications: Flow Cytometry, IHC -
CD56dim CD57- NKG2C+ NK cells retaining proliferative potential are possible precursors of CD57+ NKG2C+ memory-like NK cells
Authors: PA Kobyzeva, MA Streltsova, SA Erokhina, LM Kanevskiy, WG Telford, AM Sapozhniko, EI Kovalenko
J. Leukoc. Biol., 2020-09-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Genetic and Molecular Basis of Heterogeneous NK Cell Responses against Acute Leukemia
Authors: DR Makanga, F Da Rin de, G David, C Willem, L Dubreuil, N Legrand, T Guillaume, P Peterlin, A Lebourgeoi, MC Béné, A Garnier, P Chevallier, K Gendzekhad, A Cesbron, K Gagne, B Clemenceau, C Retière
Cancers (Basel), 2020-07-16;12(7):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Ebola virus glycoprotein stimulates IL-18 dependent natural killer cell responses
Authors: HR Wagstaffe, EA Clutterbuc, V Bockstal, JN Stoop, K Luhn, MJ Douoguih, G Shukarev, MD Snape, AJ Pollard, EM Riley, M Goodier
J. Clin. Invest., 2020-07-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In�Vivo Persistence and Enhances Anti-tumor Activity
Authors: H Zhu, RH Blum, D Bernareggi, EH Ask, Z Wu, HJ Hoel, Z Meng, C Wu, KL Guan, KJ Malmberg, DS Kaufman
Cell Stem Cell, 2020-06-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Responsiveness to Influenza Vaccination Correlates with NKG2C-Expression on NK Cells
Authors: P Riese, S Trittel, RD Pathirana, F Klawonn, RJ Cox, CA Guzmán
Vaccines (Basel), 2020-06-05;8(2):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients.
Authors: Samarani S, Sagala P, Jantchou P, Grimard G, Faure C, Deslandres C, Amre D, Ahmad A
Mediators Inflamm, 2020-02-19;2020(0):6401969.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells
Authors: EO Ojo, AA Sharma, R Liu, S Moreton, MA Checkley-L, K Gupta, G Lee, DA Lee, F Otegbeye, RP Sekaly, M de Lima, DN Wald
Sci Rep, 2019-10-17;9(1):14916.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cryopreserved Human Natural Killer Cells Exhibit Potent Antitumor Efficacy against Orthotopic Pancreatic Cancer through Efficient Tumor-Homing and Cytolytic Ability (Running Title: Cryopreserved NK Cells Exhibit Antitumor Effect)
Authors: E Oh, B Min, Y Li, C Lian, J Hong, GM Park, B Yang, SY Cho, YK Hwang, CO Yun
Cancers (Basel), 2019-07-09;11(7):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8? T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia
Authors: WC Pump, T Kraemer, T Huyton, GT Hò, R Blasczyk, C Bade-Doedi
Int J Mol Sci, 2019-03-22;20(6):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses
Authors: ECY Wang, M Pjechova, K Nightingal, VM Vlahava, M Patel, E Ruckova, SK Forbes, L Nobre, R Antrobus, D Roberts, CA Fielding, S Seirafian, J Davies, I Murrell, B Lau, GS Wilkie, NM Suárez, RJ Stanton, B Vojtesek, A Davison, PJ Lehner, MP Weekes, GWG Wilkinson, P Tomasec
Proc. Natl. Acad. Sci. U.S.A., 2018-04-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Endometrial natural killer (NK) cells reveal a tissue-specific receptor repertoire
Authors: D Feyaerts, T Kuret, B van Cranen, S van der Ze, OWH van der He, A van der Me, I Joosten, RG van der Mo
Hum. Reprod., 2018-03-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Complete Remission with Reduction of High-risk Clones following Haploidentical NK Cell Therapy against MDS and AML
Authors: AT Björklund, M Carlsten, E Sohlberg, LL Liu, T Clancy, M Karimi, S Cooley, JS Miller, M Klimkowska, M Schaffer, E Watz, KI Wikstrom, P Blomberg, BE Wahlin, M Palma, L Hansson, P Ljungman, E Hellström-, HG Ljunggren, KJ Malmberg
Clin. Cancer Res., 2018-02-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The Clinical Features of Patients with Chronic Hepatitis C Virus Infections Are Associated with Killer Cell Immunoglobulin-Like Receptor Genes and Their Expression on the Surface of Natural Killer Cells
Authors: A Podhorzer, M Dirchwolf, A Machicote, S Belen, S Montal, S Paz, H Fainboim, LG Podestá, L Fainboim
Front Immunol, 2018-01-05;8(0):1912.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Elevated Neopterin Levels Predict Early Death in Older Hip-fracture Patients
Authors: M Larsen, C Bayard, H Lepetitcor, J Cohen-Bitt, V Appay, J Boddaert, D Sauce
EBioMedicine, 2017-11-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Antibody-Dependent NK Cell Activation Differentially Targets EBV-Infected Cells in Lytic Cycle and Bystander B Lymphocytes Bound to Viral Antigen-Containing Particles
Authors: M López-Mont, E Alari-Pahi, J Sintes, JE Martínez-R, A Muntasell, M López-Bote
J. Immunol., 2017-06-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Enhancement of cytokine-driven NK cell IFN-? production after vaccination of HCMV infected Africans
Authors: A Darboe, E Danso, E Clarke, A Umesi, E Touray, R Wegmuller, SE Moore, EM Riley, MR Goodier
Eur. J. Immunol., 2017-04-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
Immun Ageing, 2017-02-22;14(0):5.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
CD2-CD58 interactions are pivotal for the activation and function of adaptive natural killer cells in human cytomegalovirus infection
Eur J Immunol, 2016-08-29;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection
Authors: Martin R Goodier
J Immunol, 2016-05-27;197(1):313-25.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells
Authors: P Rettman, C Willem, G David, R Riou, N Legrand, J Esbelin, A Cesbron, D Senitzer, K Gagne, C Retière
J Leukoc Biol, 2016-04-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts.
Authors: Picardi A, Mengarelli A, Marino M, Gallo E, Benevolo M, Pescarmona E, Cocco R, Fraioli R, Tremante E, Petti M, De Fabritiis P, Giacomini P
J Exp Clin Cancer Res, 2015-09-11;34(0):98.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Natural Killer p46 Controls Hepatitis B Virus Replication and Modulates Liver Inflammation.
Authors: Li W, Jiang Y, Wang X, Jin J, Qi Y, Chi X, Zhang H, Feng X, Niu J
PLoS ONE, 2015-08-20;10(8):e0135874.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education.
Authors: Marquardt N, Ivarsson M, Blom K, Gonzalez V, Braun M, Falconer K, Gustafsson R, Fogdell-Hahn A, Sandberg J, Michaelsson J
J Immunol, 2015-08-17;195(7):3262-72.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
NK Cell and Ig Interplay in Defense against Herpes Simplex Virus Type 1: Epistatic Interaction of CD16A and IgG1 Allotypes of Variable Affinities Modulates Antibody-Dependent Cellular Cytotoxicity and Susceptibility to Clinical Reactivation.
Authors: Moraru M, Black L, Muntasell A, Portero F, Lopez-Botet M, Reyburn H, Pandey J, Vilches C
J Immunol, 2015-07-15;195(4):1676-84.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.
Authors: Dunphy S, Guinan K, Chorcora C, Jayaraman J, Traherne J, Trowsdale J, Pende D, Middleton D, Gardiner C
Genes Immun, 2015-05-07;16(5):301-10.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals.
Authors: Nielsen C, White M, Bottomley C, Lusa C, Rodriguez-Galan A, Turner S, Goodier M, Riley E
J Immunol, 2015-04-08;194(10):4657-67.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset.
Authors: van Meijgaarden K, Haks M, Caccamo N, Dieli F, Ottenhoff T, Joosten S
PLoS Pathog, 2015-03-24;11(3):e1004671.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
Authors: Marquardt N, Beziat V, Nystrom S, Hengst J, Ivarsson M, Kekalainen E, Johansson H, Mjosberg J, Westgren M, Lankisch T, Wedemeyer H, Ellis E, Ljunggren H, Michaelsson J, Bjorkstrom N
J Immunol, 2015-02-11;194(6):2467-71.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Elevated plasma soluble CD14 and skewed CD16+ monocyte distribution persist despite normalisation of soluble CD163 and CXCL10 by effective HIV therapy: a changing paradigm for routine HIV laboratory monitoring?
Authors: Castley, Alison, Berry, Cassandr, French, Martyn, Fernandez, Sonia, Krueger, Romano, Nolan, David
PLoS ONE, 2014-12-29;9(12):e115226.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Dopamine inhibits the effector functions of activated NK cells via the upregulation of the D5 receptor.
Authors: Mikulak J, Bozzo L, Roberto A, Pontarini E, Tentorio P, Hudspeth K, Lugli E, Mavilio D
J Immunol, 2014-08-15;193(6):2792-800.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection.
Authors: Golden-Mason L, Hahn Y, Strong M, Cheng L, Rosen H
PLoS ONE, 2014-07-30;9(7):e103219.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Tracking in vivo dynamics of NK cells transferred in patients undergoing stem cell transplantation.
Authors: Killig M, Friedrichs B, Meisig J, Gentilini C, Bluthgen N, Loddenkemper C, Labopin M, Basara N, Pfrepper C, Niederwieser D, Uharek L, Romagnani C
Eur J Immunol, 2014-06-30;44(9):2822-34.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Long-term effect on natural killer cells by interferon-alpha therapy on the outcomes of HCV infection.
Authors: Hu X, Jiang Y, Li X, Gao Y, Guo X, Chi X, Yan H, Feng J, Zhong J, Sun B, Shao X, Xiao W, Pan Y, Niu J
J Interferon Cytokine Res, 2013-12-24;34(5):366-75.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients.
Authors: Achour, Abla, Baychelier, Florence, Besson, Caroline, Arnoux, Armelle, Marty, Michel, Hannoun, Laurent, Samuel, Didier, Debre, Patrice, Vieillard, Vincent
J Immunol, 2013-12-04;192(1):503-11.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Human cytomegalovirus infection elicits new decidual natural killer cell effector functions.
Authors: Siewiera J, El Costa H, Tabiasco J, Berrebi A, Cartron G, Le Bouteiller P, Jabrane-Ferrat N
PLoS Pathog, 2013-04-04;9(4):e1003257.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Authors: Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M
Eur J Immunol, 2012-12-12;43(2):480-7.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Natural killer cells are characterized by the concomitantly increased interferon-gamma and cytotoxicity in acute resolved hepatitis B patients.
Authors: Zhao J, Li Y, Jin L, Zhang S, Fan R, Sun Y, Zhou C, Shang Q, Li W, Zhang Z, Wang F
PLoS ONE, 2012-11-01;7(11):e49135.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Human Cytomegalovirus (CMV)-Induced Memory-like NKG2C+ NK Cells Are Transplantable and Expand In Vivo in Response to Recipient CMV Antigen.
Authors: Foley, Bree, Cooley, Sarah, Verneris, Michael, Curtsinger, Julie, Luo, Xianghua, Waller, Edmund K, Anasetti, Claudio, Weisdorf, Daniel, Miller, Jeffrey
J Immunol, 2012-10-17;189(10):5082-8.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients.
Authors: Beziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, Boudifa A, Hervier B, Theodorou I, Martinot M, Debre P, Bjorkstrom NK, Malmberg KJ, Marcellin P, Vieillard V
Eur. J. Immunol., 2011-12-16;42(2):447-57.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus.
Authors: Bjorkstrom NK, Lindgren T, Stoltz M, Fauriat C, Braun M, Evander M, Michaelsson J, Malmberg KJ, Klingstrom J, Ahlm C, Ljunggren HG
J. Exp. Med., 2010-12-20;208(1):13-21.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Analysis of CD16+CD56dim NK cells from CLL patients: evidence supporting a therapeutic strategy with optimized anti-CD20 monoclonal antibodies.
Authors: Le Garff-Tavernier M, Decocq J, de Romeuf C, Parizot C, Dutertre CA, Chapiro E, Davi F, Debre P, Prost JF, Teillaud JL, Merle-Beral H, Vieillard V
Leukemia, 2010-10-26;25(1):101-9.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
NKG2A inhibits NKG2C effector functions of gammadelta T cells: implications in health and disease.
Authors: Angelini DF, Zambello R, Galandrini R, Diamantini A, Placido R, Micucci F, Poccia F, Semenzato G, Borsellino G, Santoni A, Battistini L
J. Leukoc. Biol., 2010-10-15;89(1):75-84.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs.
Authors: Beziat V, Descours B, Parizot C, Debre P, Vieillard V
PLoS ONE, 2010-08-06;5(8):e11966.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy.
Authors: Spanholtz J, Tordoir M, Eissens D, Preijers F, van der Meer A, Joosten I, Schaap N, de Witte TM, Dolstra H
PLoS ONE, 2010-02-15;5(2):e9221.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Shaping of iNKT cell repertoire after unrelated cord blood transplantation.
Authors: Beziat V, Nguyen S, Exley M, Achour A, Simon T, Chevallier P, Sirvent A, Vigouroux S, Debre P, Rio B, Vieillard V, Lubrano-Berthelier C, Alatrakchi N
Clin. Immunol., 2010-02-13;135(3):364-73.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia.
Authors: Brunetta E, Fogli M, Varchetta S, Bozzo L, Hudspeth KL, Marcenaro E, Moretta A, Mavilio D
Blood, 2009-08-26;114(18):3822-30.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.
Authors: Dulphy N, Haas P, Busson M, Belhadj S, Peffault de Latour R, Robin M, Carmagnat M, Loiseau P, Tamouza R, Scieux C, Rabian C, Di Santo JP, Charron D, Janin A, Socie G, Toubert A
J. Immunol., 2008-08-01;181(3):2227-37.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Establishment and characterization of SRIK-NKL: a novel CD8+ natural killer/T cell line derived from a patient with leukemic phase of acute lymphoblastic lymphoma.
Authors: Srivastava BI, Srivastava MD
Leuk. Res., 2005-07-01;29(7):771-83.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
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