Human NKp30/NCR3 (NP_667341) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC1510
R&D Systems VersaClone cDNA Plasmids
1 Image
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Human NKp30/NCR3 (NP_667341) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: NKp30/NCR3

NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.

Entrez Gene IDs
259197 (Human); 294251 (Rat); 102133932 (Cynomolgus Monkey)
Alternate Names
Activating natural killer receptor p30; CD337 antigen; CD337; CD337activating NK-A1 receptor; LY117,1C7NK-p30; lymphocyte antigen 117; natural cytotoxicity triggering receptor 3; Natural killer cell p30-related protein; NCR3; NKp30; NKp30MALS

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