Home / Orexin R2/HCRTR2 / Human Orexin R2/HCRTR2 (AAC39602) VersaClone cDNA

Human Orexin R2/HCRTR2 (AAC39602) VersaClone cDNA

Catalog #: RDC0522 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
RDC0522
R&D Systems VersaClone cDNA Plasmids
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Human Orexin R2/HCRTR2 (AAC39602) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: Orexin R2/HCRTR2

Hypocretin receptor 2 (HCRTR2); also known as orexin receptor 2 or OX2R is a 40 kDa 7-transmembrane G-protein-coupled glycoprotein that is a high affinity receptor for orexins A and B (hypocretins 1 and 2). In mouse brain, engagement of HCRTRs promotes wakefulness, such that absence of either orexins or their receptors creates a narcolepsy-like state. HCRTR2 also influences reward circuits involving food or addictive drugs. The extracellular portions of human HCRTR2 share 92% and 93% aa identity with corresponding portions of mouse and rat HCRTR2, respectively.

Long Name
Hypocretin Receptor Type 2
Entrez Gene IDs
3062 (Human); 387285 (Mouse); 25605 (Rat)
Alternate Names
HCRTR2; hypocretin (orexin) receptor 2; Hypocretin receptor type 2; Orexin R2; Orexin Receptor 2; orexin receptor type 2; OrexinR2; OX2R; Ox-2-R; ox2-R

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