Human Osteocrin Antibody

Catalog # Availability Size / Price Qty
MAB96691-100
MAB96691-SP
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Human Osteocrin Antibody Summary

Species Reactivity
Human
Specificity
Detects human Osteocrin in direct ELISAs.
Source
Monoclonal Rat IgG2A Clone # 311326
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human Osteocrin
Val28-Gly133
Accession # P61366
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
ELISA

This antibody functions as an ELISA detection antibody when paired with Rat Anti-Human Osteocrin Monoclonal Antibody (Catalog # MAB9669).

This product is intended for assay development on various assay platforms requiring antibody pairs.

 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Osteocrin

Osteocrin, also known as Musclin, is a secreted protein that is primarily expressed in bone and muscle. It is synthesized as a proprotein that undergoes proteolytic processing to generate a mature 50 amino acid C-terminal active peptide. It was found to modulate osteoblast differentiation and to regulate glucose metabolism in muscles. Human Osteocrin proprotein shares 77% and 78% amino acid sequence identity with the rat and mouse protein, respectively.

Entrez Gene IDs
344901 (Human); 239790 (Mouse)
Alternate Names
Musclin; Osteocrin; OSTN

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