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Human PNR/NR2E3 Antibody

Catalog #: PP-H7223-00
11 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
PP-H7223-00
Product Details
Citations (11)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PNR/NR2E3 Antibody Summary

Species Reactivity
Human
Source
Monoclonal Mouse IgG2a Clone # H7223
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
Please refer to the PDF datasheet for specifications.
Immunohistochemistry
5-15 µg/mL
Perfusion fixed paraffin-embedded sections of rat retina (outer nuclear layer)
Direct ELISA
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: PNR/NR2E3

Photoreceptor-specific Nuclear Receptor (PNR, RNR; NR2E3) is a member of the orphan nuclear receptor superfamily. PNR is expressed in the retina and plays a role in retinal photoreceptor cell differentiation and degeneration.

Long Name
Photoreceptor-specific Nuclear Receptor
Entrez Gene IDs
10002 (Human)
Alternate Names
NR2E3; Nuclear receptor subfamily 2 group E member 3; nuclear receptor subfamily 2, group E, member 3; photoreceptor-specific nuclear receptor; PNR; PNRESCS; rd7; Retina-specific nuclear receptor; RNR; RP37MGC49976

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Citations for Human PNR/NR2E3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

11 Citations: Showing 1 - 10
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  1. Lamin A upregulation reorganizes the genome during rod photoreceptor degeneration
    Authors: Herrera, I;Fernandes, JAL;Shir-Mohammadi, K;Levesque, J;Mattar, P;
    Cell death & disease
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  2. Automating iPSC generation to enable autologous photoreceptor cell replacement therapy
    Authors: LR Bohrer, NE Stone, NK Mullin, AP Voigt, KR Anfinson, JL Fick, V Luangphakd, B Hittle, K Powell, GF Muschler, RF Mullins, EM Stone, BA Tucker
    Journal of Translational Medicine, 2023-02-28;21(1):161.
    Species: Human
    Sample Types: Organoid
    Applications: IHC
  3. Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats
    Authors: IC Han, LR Bohrer, KN Gibson-Cor, LA Wiley, A Shrestha, BE Harman, C Jiao, EH Sohn, R Wendland, BN Allen, KS Worthingto, RF Mullins, EM Stone, BA Tucker
    Cell Transplantation, 2022-01-01;31(0):9636897221104.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  4. Setd1a Plays Pivotal Roles for the Survival and Proliferation of Retinal Progenitors via Histone Modifications of Uhrf1
    Authors: X Deng, T Iwagawa, M Fukushima, Y Suzuki, S Watanabe
    Investigative Ophthalmology & Visual Science, 2021-05-03;62(6):1.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids
    Authors: H Xie, W Zhang, M Zhang, T Akhtar, Y Li, W Yi, X Sun, Z Zuo, M Wei, X Fang, Z Yao, K Dong, S Zhong, Q Liu, Y Shen, Q Wu, X Wang, H Zhao, J Bao, K Qu, T Xue
    Sci Adv, 2020-02-07;6(6):eaay5247.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  6. Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors
    Authors: Diego F. Buenaventura, Adrianne Corseri, Mark M. Emerson
    Investigative Opthalmology & Visual Science
  7. Identification and characterization of early photoreceptor cis-regulatory elements and their relation to Onecut1
    Authors: Nathalie Jean-Charles, Diego F. Buenaventura, Mark M. Emerson
    Neural Development
  8. Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis
    Authors: Angelica M. Kowalchuk, Kate A. Maurer, Farnaz Shoja-Taheri, Nadean L. Brown
    Developmental Biology
  9. Small molecule Photoregulin3 prevents retinal degeneration in the RhoP23H mouse model of retinitis pigmentosa
    Authors: PA Nakamura, AA Shimchuk, S Tang, Z Wang, K DeGolier, S Ding, TA Reh
    Elife, 2017-11-17;6(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation
  10. Transplantation of photoreceptors derived from human Muller glia restore rod function in the P23H rat.
    Authors: Jayaram H, Jones M, Eastlake K, Cottrill P, Becker S, Wiseman J, Khaw P, Limb G
    Stem Cells Transl Med, 2014-01-29;3(3):323-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  11. Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures
    Authors: A Sridhar, A Hoshino, CR Finkbeiner, A Chitsazan, L Dai, AK Haugan, KM Eschenbach, DL Jackson, C Trapnell, O Bermingham, I Glass, TA Reh
    Cell Rep, 2020-02-04;30(5):1644-1659.e4.

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