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Human/Primate VEGF Antibody

Catalog #: MAB293
110 Citations 8 Reviews Datasheet / COA / SDS
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MAB293-SP
MAB293-100
MAB293-500
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Detection of Recombinant Human VEGF by Western Blot.
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Citations (110)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Primate VEGF Antibody Summary

Species Reactivity
Human, Primate
Specificity
Detects human VEGF165 and human VEGF121 in ELISAs and Western blots. In ELISAs, approximately 10% cross-reactivity with recombinant mouse (rm) VEGF and recombinant rat (rr)VEGF and no cross-reactivity with recombinant human (rh) VEGF-D is obseved.
Source
Monoclonal Mouse IgG2B Clone # 26503
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF165
Ala27-Arg191
Accession # NP_001165097.1
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
See below

Human/Primate VEGF Sandwich Immunoassay

Recommended Concentration
Reagent
ELISA Capture (Matched Antibody Pair)
2-8 µg/mL 

Use in combination with:

Detection Reagent: Human/Primate VEGF165 Biotinylated Antibody (Catalog # BAF293)

Standard: Recombinant Human VEGF 165 Protein (Catalog # 293-VE)

Neutralization
Measured by its ability to neutralize VEGF165-induced proliferation in HUVEC human umbilical vein endothelial cells. The Neutralization Dose (ND50) is typically 10-60 ng/mL in the presence of 10 ng/mL Recombinant Human VEGF165.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Recombinant Human VEGF antibody by Western Blot. View Larger

Detection of Recombinant Human VEGF by Western Blot. Western blot shows 25 ng of Recombinant Human VEGF165(Catalog # 293-VE), Recombinant Human VEGF111(Catalog # 5336-VE), Recombinant Human VEGF121, aa 207-327 (Catalog # 4644-VS), Recombinant Human VEGF145(aa 27-171) (Catalog # 7626-VE), Recombinant Human VEGF162(Catalog # 2347-VE), Recombinant Human VEGF165b(Catalog # 3045-VE), Recombinant Human VEGF189(aa 27-215) (Catalog # 8147-VE), Recombinant Human VEGF165Extended Isoform (Catalog # 9018-VE), Recombinant Human VEGF-B167(Catalog # 751-VE), Recombinant Mouse VEGF164(Catalog # 493-MV), and Recombinant Rat VEGF164(Catalog # 564-RV). PVDF Membrane was probed with 0.1 µg/mL of Mouse Anti-Human/Primate VEGF Monoclonal Antibody (Catalog # MAB293) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for VEGF at approximately 15-25 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 3.

Neutralization Cell Proliferation Induced by VEGF<sub>165</sub>and Neutralization by Human VEGF Antibody. View Larger

Cell Proliferation Induced by VEGF165and Neutralization by Human VEGF Antibody. Recombinant Human VEGF165(Catalog # 293-VE) stimulates proliferation in HUVEC human umbilical vein endothelial cells in a dose-dependent manner (orange line) as measured by Resazurin (Catalog # AR002). Proliferation elicited by Recombinant Human VEGF165(10 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human/Primate VEGF Monoclonal Antibody (Catalog # MAB293). The ND50 is typically 10-60 ng/mL.

Western Blot Detection of Rat VEGF by Western Blot View Larger

Detection of Rat VEGF by Western Blot Protein levels of VEGF (A), KDR (VEGF receptor 2, B), Angiopoietin 1 (C) and Tie2 (D) from retinal endothelial cells cultured in normoxia or hypoxia only and cells in each condition treated with Compound 49b. Hypoxia increased protein levels of all proteins, which were significantly reduced after treatment with Compound 49b. Data is mean ± SEM. *P<0.05 vs. normoxia. #P<0.05 vs. hypoxia. N = 4. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/27439004), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VEGF

Vascular Endothelial Growth Factor (VEGF or VEGF-A), also known as Vascular Permeability Factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues and a cystine knot structure. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. Human VEGF165 is an approximately 44 kDa molecular weight homodimer sharing 88% aa sequence identity with corresponding regions of mouse and rat, 96% with porcine, 95% with canine, and 93% with feline, equine and bovine VEGF, respectively. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt-1) and VEGF R2 (Flk-1/KDR) on endothelial cells. Although VEGF affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity. VEGF165 binds the Semaphorin receptor, Neuropilin-1 and promotes complex formation with VEGF R2. VEGF is required during embryogenesis and functions to regulate the proliferation, migration, and survival of endothelial cells. In adults, VEGF functions mainly in wound healing and the female reproductive cycle. Pathologically, it is involved in tumor angiogenesis and vascular leakage. Circulating VEGF levels correlate with disease activity in autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus. VEGF is induced by hypoxia and cytokines such as IL-1, IL-6, IL-8, Oncostatin M (OSM) and TNF-alpha.

Long Name
Vascular Endothelial Growth Factor
Entrez Gene IDs
7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
Alternate Names
MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGF; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor

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Citations for Human/Primate VEGF Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

110 Citations: Showing 1 - 10
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  1. Overexpression of Antiangiogenic Vascular Endothelial Growth Factor Isoform and Splicing Regulatory Factors in Oral, Laryngeal and Pharyngeal Squamous Cell Carcinomas
    Authors: Patrícia Matos Biselli-Chicote, Joice Matos Biselli, Bianca R Cunha, Rodrigo Castro, José Victor Maniglia, Dalísio de Santi Neto et al.
    Asian Pac. J. Cancer Prev
  2. NFAT5/STAT3 interaction mediates synergism of high salt with IL-17 towards induction of VEGF-A expression in breast cancer cells
    Authors: Suneetha Amara, Dalal Alotaibi, Venkataswarup Tiriveedhi
    Oncology Letters
  3. Recombinant Human VEGF165b Inhibits Experimental Choroidal Neovascularization
    Authors: Jing Hua, Christine Spee, Satoru Kase, Emma S. Rennel, Anette L. Magnussen, Yan Qiu et al.
    Investigative Opthalmology & Visual Science
  4. Intrathecal B Cells in MS Have Significantly Greater Lymphangiogenic Potential Compared to B Cells Derived From Non-MS Subjects
    Authors: Jason Stein, Quangang Xu, Kayla C. Jackson, Elena Romm, Simone C. Wuest, Peter Kosa et al.
    Frontiers in Neurology
  5. Compound 49b Restores Retinal Thickness and Reduces Degenerate Capillaries in the Rat Retina following Ischemia/Reperfusion
    PLoS ONE, 2016-07-20;11(7):e0159532.
  6. Application of a Glucose Dehydrogenase-Fused with Zinc Finger Protein to Label DNA Aptamers for the Electrochemical Detection of VEGF
    Authors: Jinhee Lee, Atsuro Tatsumi, Kaori Tsukakoshi, Ellie D. Wilson, Koichi Abe, Koji Sode et al.
    Sensors (Basel)
  7. Small Extracellular Vesicle‐Derived vWF Induces a Positive Feedback Loop between Tumor and Endothelial Cells to Promote Angiogenesis and Metastasis in Hepatocellular Carcinoma
    Authors: Samuel Wan Ki Wong, Sze Keong Tey, Xiaowen Mao, Hiu Ling Fung, Zhi‐Jie Xiao, Danny Ka Ho Wong et al.
    Advanced Science
  8. Thymosin ?4 promotes endothelial progenitor cell angiogenesis via a vascular endothelial growth factor?dependent mechanism
    Authors: Y Zhao, J Song, X Bi, J Gao, Z Shen, J Zhu, G Fu
    Mol Med Rep, 2018-06-20;18(2):2314-2320.
  9. VEGF −460T → C polymorphism and its association with VEGF expression and outcome to FOLFOX-4 treatment in patients with colorectal carcinoma
    Authors: M-H Chen, C-H Tzeng, P-M Chen, J-K Lin, T-C Lin, W-S Chen et al.
    The Pharmacogenomics Journal
  10. Activated androgen receptor accelerates angiogenesis in cutaneous neurofibroma by regulating VEGFA transcription
    Authors: Jing Jia, Haibao Zhang, Hongke Zhang, Huicong Du, Wenbo Liu, Maoguo Shu
    International Journal of Oncology
  11. IL-4/IL-13 Stimulated Macrophages Enhance Breast Cancer Invasion Via Rho-GTPase Regulation of Synergistic VEGF/CCL-18 Signaling
    Authors: Andrew C. Little, Pragathi Pathanjeli, Zhifen Wu, Liwei Bao, Laura E. Goo, Joel A. Yates et al.
    Frontiers in Oncology
  12. Endocytosis and serpentine filopodia drive blebbishield-mediated resurrection of apoptotic cancer stem cells
    Authors: Goodwin G Jinesh, Ashish M Kamat
    Cell Death Discovery
  13. Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion
    Authors: J. Konen, E. Summerbell, B. Dwivedi, K. Galior, Y. Hou, L. Rusnak et al.
    Nature Communications
  14. Smad4 inhibits cell migration via suppression of JNK activity in human pancreatic carcinoma PANC-1 cells
    Authors: XUEYING ZHANG, JUNXIA CAO, YUJUN PEI, JIYAN ZHANG, QINGYANG WANG
    Oncology Letters
  15. Functional Relevance of the Switch of VEGF Receptors/Co-Receptors during Peritoneal Dialysis-Induced Mesothelial to Mesenchymal Transition
    Authors: María Luisa Pérez-Lozano, Pilar Sandoval, Ángela Rynne-Vidal, Abelardo Aguilera, José Antonio Jiménez-Heffernan, Patricia Albar-Vizcaíno et al.
    PLoS ONE
  16. The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1 alpha -dependent and -independent manners
    Authors: Yanan Zhang, Jie Liu, Shibin Wang, Xiaoli Luo, Yang Li, Zhaohui Lv et al.
    Oncotarget
  17. Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling
    Authors: Akiyoshi Komuro, Masakazu Yashiro, Caname Iwata, Yasuyuki Morishita, Erik Johansson, Yoshiko Matsumoto et al.
    JNCI: Journal of the National Cancer Institute
  18. Influence of VEGF-A, VEGFR-1-3, and neuropilin 1-2 on progression-free: and overall survival in WHO grade II and III meningioma patients
    Authors: Simon Bernatz, Daniel Monden, Florian Gessler, Tijana Radic, Elke Hattingen, Christian Senft et al.
    Journal of Molecular Histology
  19. NRP-1 interacts with GIPC1 and SYX to activate p38 MAPK signaling and cancer stem cell survival
    Authors: Daniel Grun, Gautam Adhikary, Richard L. Eckert
    Molecular Carcinogenesis
  20. Capecitabine metronomic chemotherapy inhibits the proliferation of gastric cancer cells through anti-angiogenesis
    Authors: FEI YUAN, HAILONG SHI, JUN JI, QU CAI, XUEHUA CHEN, YINGYAN YU et al.
    Oncology Reports
  21. FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol
    Authors: Rakesh K. Srivastava, Terry G. Unterman, Sharmila Shankar
    Molecular and Cellular Biochemistry
  22. Upregulation of stromal cell derived factor-1alpha in collagen vascular diseases-associated interstitial pneumonias (CVDs-IPs)
    Authors: Giorgos A. Margaritopoulos, Katerina M. Antoniou, Giannoula Soufla, Konstantinos Karagiannis, Athanasia Proklou, Ismini Lasithiotaki et al.
    Pulmonary Pharmacology & Therapeutics
  23. Anti-VEGF drug interference with VEGF quantitation in the R&D systems human quantikine VEGF ELISA kit
    Authors: Giane Sumner, Camille Georgaros, Ashique Rafique, Thomas DiCioccio, Joel Martin, Nicholas Papadopoulos et al.
    Bioanalysis
  24. Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity
    Authors: Lavinia Raimondi, Nicola Amodio, Maria Teresa Di Martino, Emanuela Altomare, Marzia Leotta, Daniele Caracciolo et al.
    Oncotarget
  25. The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer
    Authors: Yanan Zhang, Jie Liu, Jing Lin, Lei Zhou, Yuhua Song, Bo Wei et al.
    Oncotarget
  26. Unravelling heterogeneous effects of cancer?associated fibroblasts on poor prognosis markers in breast cancer EM?G3 cell line: In vitro?targeted treatment (anti?IL-6, anti?VEGF-A, anti?MFGE8) based on transcriptomic profiling
    Authors: Urban, L;Novák, Š;?oma, M;Dvo?ánková, B;Lacina, L;Šáchová, J;Hradilová, M;Svato?ová, P;Kolá?, M;Strnad, H;B?ezinová, J;Smetana, K;Gál, P;Szabo, P;
    Oncology reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  27. CD40 Ligand-CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy
    Authors: Abu El-Asrar, AM;Nawaz, MI;Ahmad, A;Dillemans, L;Siddiquei, M;Allegaert, E;Gikandi, PW;De Hertogh, G;Opdenakker, G;Struyf, S;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  28. Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system
    Authors: A Weigert, X Zheng, A Nenzel, K Turkowski, S Günther, E Strack, E Sirait-Fis, E Elwakeel, IM Kur, VS Nikam, C Valasaraja, H Winter, A Wissgott, R Voswinkel, F Grimminger, B Brüne, W Seeger, SS Pullamsett, R Savai
    Nature Communications, 2022-10-14;13(1):6078.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  29. Effects of Human Deciduous Dental Pulp-Derived Mesenchymal Stem Cell-Derived Conditioned Medium on the Metabolism of HUVECs, Osteoblasts, and BMSCs
    Authors: R Kunimatsu, T Hiraki, K Rikitake, K Nakajima, NAR Putranti, T Abe, K Ando, A Nakatani, S Sakata, K Tanimoto
    Cells, 2022-10-14;11(20):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ELISA Development, Neutralization
  30. Inhibition of the VEGF signaling pathway attenuates tumor?associated macrophage activity in liver cancer
    Authors: S Okikawa, Y Morine, Y Saito, S Yamada, K Tokuda, H Teraoku, K Miyazaki, S Yamashita, T Ikemoto, S Imura, M Shimada
    Oncology reports, 2022-02-16;47(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  31. Tissue Inhibitor of Metalloproteinase-3 Ameliorates Diabetes-Induced Retinal Inflammation
    Authors: AM Abu El-Asr, A Ahmad, MI Nawaz, MM Siddiquei, A De Zutter, L Vanbrabant, PW Gikandi, G Opdenakker, S Struyf
    Frontiers in Physiology, 2022-01-10;12(0):807747.
    Species: Rat
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  32. CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy
    Authors: AM Abu El-Asr, MI Nawaz, A Ahmad, MM Siddiquei, E Allegaert, PW Gikandi, G De Hertogh, G Opdenakker
    Investigative Ophthalmology & Visual Science, 2021-07-01;62(9):32.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  33. 3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration
    Authors: KV Manian, CA Galloway, S Dalvi, AA Emanuel, JA Mereness, W Black, L Winschel, C Soto, Y Li, Y Song, W DeMaria, A Kumar, I Slukvin, MP Schwartz, WL Murphy, B Anand-Apte, M Chung, DSW Benoit, R Singh
    Cell Stem Cell, 2021-03-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  34. Chrysin Inhibits High Glucose-Induced Migration on Chorioretinal Endothelial Cells via VEGF and VEGFR Down-Regulation
    Authors: ZY Liao, IC Liang, HJ Li, CC Wu, HM Lo, DC Chang, CF Hung
    Int J Mol Sci, 2020-08-02;21(15):.
    Species: Primate, Rhesus Macaque
    Sample Types: Cell Lysates
    Applications: Western Blot
  35. Snail promotes the generation of vascular endothelium by breast cancer cells
    Authors: Z Chang, Y Zhang, J Liu, Y Zheng, H Li, Y Kong, P Li, H Peng, Y Shi, B Cao, F Ran, Y Chen, Y Song, Q Ye, L Ding
    Cell Death Dis, 2020-06-15;11(6):457.
    Species: Human
    Sample Types: Transduced Whole Cells
    Applications: Neutralization
  36. Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth
    Authors: HA Oh, J Kwak, BJ Kim, HJ Jin, WS Park, SJ Choi, W Oh, S Um
    Cells, 2020-05-28;9(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  37. Quercetin attenuates adipose hypertrophy, in part through activation of adipogenesis in rats fed a high-fat diet
    Authors: DJ Perdicaro, C Rodriguez, J Gambarte T, RM Miatello, PI Oteiza, MA Vazquez Pr
    J. Nutr. Biochem., 2020-02-04;79(0):108352.
    Species: Rat
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  38. Contribution of the VEGF system to the follicular persistence associated with bovine cystic ovaries
    Authors: AF Stassi, F Gasser, MML Velázquez, EM Belotti, NC Gareis, F Rey, HH Ortega, NR Salvetti, ME Baravalle
    Theriogenology, 2019-07-03;138(0):52-65.
    Species: Bovine, Mouse
    Sample Types: Cell Lysates, Tissue Homogenates, Whole Tissue
    Applications: IHC, IHC-P, Western Blot
  39. TSP-1 is downregulated and inversely correlates with miR-449c expression in Cushing's disease
    Authors: J Ren, C Gu, Y Yang, J Xue, Y Sun, F Jian, D Chen, L Bian, Q Sun
    J. Cell. Mol. Med., 2019-04-23;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  40. TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment
    Authors: P Zizza, R Dinami, M Porru, C Cingolani, E Salvati, A Rizzo, C D'Angelo, E Petti, CA Amoreo, M Mottolese, I Sperduti, A Chambery, R Russo, P Ostano, G Chiorino, G Blandino, A Sacconi, J Cherfils-V, C Leonetti, E Gilson, A Biroccio
    Nucleic Acids Res., 2019-04-23;0(0):.
    Species: Human, Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Neutralization
  41. A Subset of Paracrine Factors as Efficient Biomarkers for Predicting Vascular Regenerative Efficacy of Mesenchymal Stromal/Stem Cells
    Authors: HK Kim, SG Lee, SW Lee, BJ Oh, JH Kim, JA Kim, G Lee, JD Jang, YA Joe
    Stem Cells, 2018-10-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  42. Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface
    Authors: MKS Tang, PYK Yue, PP Ip, RL Huang, HC Lai, ANY Cheung, KY Tse, HYS Ngan, AST Wong
    Nat Commun, 2018-06-11;9(1):2270.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  43. Grape pomace extract induced beige cells in white adipose tissue from rats and in 3T3-L1 adipocytes
    Authors: C Rodriguez, DJ Perdicaro, MS Landa, A Fontana, A Antoniolli, RM Miatello, PI Oteiza, MA Vazquez Pr
    J. Nutr. Biochem., 2018-03-10;56(0):224-233.
    Species: Rat
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  44. Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin� protein MP0250: a preclinical study
    Authors: L Rao, K De Veirman, D Giannico, I Saltarella, V Desantis, MA Frassanito, AG Solimando, D Ribatti, M Prete, A Harstrick, U Fiedler, H De Raeve, V Racanelli, K Vanderkerk, A Vacca
    Oncotarget, 2018-01-30;9(17):13366-13381.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  45. Investigating Colorimetric Protein Array Assay Schemes for Detection of Recurrence of Bladder Cancer
    Authors: S Gogalic, U Sauer, S Doppler, C Preininger
    Biosensors (Basel), 2018-01-24;8(1):.
    Species: Human
    Sample Types: Urine
    Applications: Array Development
  46. Application of an acellular dermal matrix to a rabbit model of oral mucosal defects
    Authors: X Xu, N Cui, E Wang
    Exp Ther Med, 2018-01-05;15(3):2450-2456.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  47. Predictive Value of Clinical Findings and Plasma Biomarkers after Fourteen Days of Prednisone Treatment for Acute Graft-versus-host Disease.
    Authors: McDonald G, Tabellini L, Storer B, Martin P, Lawler R, Rosinski S, Schoch H, Hansen J
    Biol Blood Marrow Transplant, 2017-05-03;23(8):1257-1263.
    Species: Human
    Sample Types: Plasma
  48. HIF1? regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia
    Authors: P Wang, C Lan, S Xiong, X Zhao, Y Shan, R Hu, W Wan, S Yu, B Liao, G Li, J Wang, D Zou, B Chen, H Feng, N Wu
    Oncotarget, 2017-04-25;8(17):28074-28092.
    Species: Human
    Sample Types: Cell Lysates, Whole Cells
    Applications: ICC, Western Blot
  49. Vessel morphometric parameters-correlation with histologic grade and VEGF expression in oligodendroglioma
    Authors: LB Strickland, S Brem, AM Rojiani, MV Rojiani
    Am J Cancer Res, 2017-04-01;7(4):973-981.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  50. Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells
    Authors: W Katagiri, T Kawai, M Osugi, Y Sugimura-W, K Sakaguchi, T Kojima, T Kobayashi
    Maxillofac Plast Reconstr Surg, 2017-03-25;39(1):8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  51. Development of a surrogate potency assay to determine the angiogenic activity of Stempeucel�, a pooled, ex-vivo expanded, allogeneic human bone marrow mesenchymal stromal cell product
    Authors: C Thej, B Ramadasse, A Walvekar, AS Majumdar, S Balasubram
    Stem Cell Res Ther, 2017-02-28;8(1):47.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  52. Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: Junctional dynamics and putative mechanisms
    Authors: Lopa Leach
    Placenta, 2016-10-21;48(0):87-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC, Neutralization
  53. The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer
    Authors: Z Jing, H Xu, X Chen, Q Zhong, J Huang, Y Zhang, W Guo, Z Yang, S Ding, P Chen, Z Huang
    PLoS ONE, 2016-04-14;11(4):e0152789.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  54. VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors
    Authors: D Grun, G Adhikary, RL Eckert
    Oncogene, 2016-01-25;35(33):4379-87.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  55. Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis.
    Authors: Mar A, Chu C, Lee H, Chien C, Cheng J, Yang S, Jiang J, Lee T
    J Biol Chem, 2015-07-24;290(36):22212-24.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  56. Pericytes contribute to the disruption of the cerebral endothelial barrier via increasing VEGF expression: implications for stroke.
    Authors: Bai Y, Zhu X, Chao J, Zhang Y, Qian C, Li P, Liu D, Han B, Zhao L, Zhang J, Buch S, Teng G, Hu G, Yao H
    PLoS ONE, 2015-04-17;10(4):e0124362.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  57. Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced beta-catenin/Tcf-Lef dependent transcription.
    Authors: Fernandez J, Rodriguez D, Valenzuela M, Calderon C, Urzua U, Munroe D, Rosas C, Lemus D, Diaz N, Wright M, Leyton L, Tapia J, Quest A
    Mol Cancer, 2014-09-09;13(0):209.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  58. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.
    Authors: Lee E, Fertig E, Jin K, Sukumar S, Pandey N, Popel A
    Nat Commun, 2014-09-02;5(0):4715.
    Species: Human
    Sample Types: In Vivo, Whole Tissue
    Applications: IHC, Neutralization
  59. Interleukin 4, interleukin 6 and osteopontin-serological markers of head and neck malignancy in primary diagnostics: A pilot study.
    Authors: Aderhold C, Grobschmidt G, Sauter A, Faber A, Hormann K, Schultz J
    Oncol Lett, 2014-07-04;8(3):1112-1118.
    Species: Human
    Sample Types: Serum
    Applications: Bioassay
  60. Control of angiogenesis by galectins involves the release of platelet-derived proangiogenic factors.
    Authors: Etulain J, Negrotto S, Tribulatti M, Croci D, Carabelli J, Campetella O, Rabinovich G, Schattner M
    PLoS ONE, 2014-04-30;9(4):e96402.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  61. Enhanced efficacy of combination therapy with adenoassociated virus-delivered pigment epithelium-derived factor and cisplatin in a mouse model of Lewis lung carcinoma.
    Authors: He S, Wu Q, Gong C, Luo S, Zhang S, Li M, Lu L, Wei Y, Yang L
    Mol Med Rep, 2014-04-04;9(6):2069-76.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  62. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
    Authors: Smith A, Bowers S, Stratman A, Davis G
    PLoS ONE, 2013-12-31;8(12):e85147.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  63. Markers of T cell infiltration and function associate with favorable outcome in vascularized high-grade serous ovarian carcinoma.
    Authors: Townsend, Katelin, Spowart, Jaeline, Huwait, Hassan, Eshragh, Sima, West, Nathan R, Elrick, Mary A, Kalloger, Steve E, Anglesio, Michael, Watson, Peter H, Huntsman, David G, Lum, Julian J
    PLoS ONE, 2013-12-23;8(12):e82406.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  64. Heat shock protein 27 attenuates neointima formation and accelerates reendothelialization after arterial injury and stent implantation: importance of vascular endothelial growth factor up-regulation.
    Authors: Ma X, Hibbert B, McNulty M, Hu T, Zhao X, Ramirez F, Simard T, de Belleroche J, O'Brien E
    FASEB J, 2013-10-18;28(2):594-602.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  65. High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1alpha.
    Authors: Tan J, Prosser H, Vanags L, Monger S, Ng M, Bursill C
    FASEB J, 2013-09-10;28(1):206-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  66. The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo.
    Authors: Merdzhanova G, Gout S, Keramidas M, Edmond V, Coll JL, Brambilla C, Brambilla E, Gazzeri S, Eymin B
    Oncogene, 2010-07-19;29(39):5392-403.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Western Blot
  67. VEGF in the lung: a role for novel isoforms.
    Authors: Varet J, Varet, Julia, Douglas SK, Douglas, Samantha, Gilmartin L, Gilmartin, Laura, Medford, Andrew R, Bates, David O, Harper, Steven J, Millar, Ann B
    Am J Physiol Lung Cell Mol Physiol, 2010-03-12;298(6):L768-74.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  68. Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.
    Authors: Hashizume H, Falcon BL, Kuroda T, Baluk P, Coxon A, Yu D, Bready JV, Oliner JD, McDonald DM
    Cancer Res., 2010-03-02;70(6):2213-23.
    Species: Human
    Sample Types: In Vivo
    Applications: Neutralization
  69. A small-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway.
    Authors: Zhu W, Ou Y, Li Y, Xiao R, Shu M, Zhou Y, Xie J, He S, Qiu P, Yan G
    Mol. Pharmacol., 2009-01-21;75(4):812-9.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  70. Development and validation of sandwich ELISA microarrays with minimal assay interference.
    Authors: Gonzalez RM, Seurynck-Servoss SL, Crowley SA
    J. Proteome Res., 2008-04-19;7(6):2406-14.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Microarray Development
  71. FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities.
    Authors: Allerstorfer S, Sonvilla G, Fischer H, Spiegl-Kreinecker S, Gauglhofer C, Setinek U, Czech T, Marosi C, Buchroithner J, Pichler J, Silye R, Mohr T, Holzmann K, Grasl-Kraupp B, Marian B, Grusch M, Fischer J, Micksche M, Berger W
    Oncogene, 2008-03-24;27(30):4180-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  72. Ultrasensitive flow-based immunoassays using single-molecule counting.
    Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
    Clin. Chem., 2007-09-21;53(11):1990-5.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Development
  73. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
    Authors: Ball SG, Shuttleworth CA, Kielty CM
    J. Cell Biol., 2007-04-30;177(3):489-500.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  74. Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts.
    Authors: Hatfield K, Ryningen A, Corbascio M, Bruserud O
    Int. J. Cancer, 2006-11-15;119(10):2313-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  75. Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential.
    Authors: Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal PM, Pesce M, Capogrossi MC, Failla CM, Napolitano M, Odorisio T
    Am. J. Pathol., 2006-10-01;169(4):1167-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  76. Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment.
    Authors: Lucerna M, Zernecke A, de Nooijer R, de Jager SC, Bot I, van der Lans C, Kholova I, Liehn EA, van Berkel TJ, Yla-Herttuala S, Weber C, Biessen EA
    Blood, 2006-09-21;109(1):122-9.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Neutralization
  77. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.
    Authors: Rofstad EK, Mathiesen B, Kindem K, Galappathi K
    Cancer Res., 2006-07-01;66(13):6699-707.
    Species: Complex Species Category
    Sample Types: In Vivo
    Applications: Neutralization
  78. The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term.
    Authors: Bates DO, MacMillan PP, Manjaly JG, Qiu Y, Hudson SJ, Bevan HS, Hunter AJ, Soothill PW, Read M, Donaldson LF, Harper SJ
    Clin. Sci., 2006-05-01;110(5):575-85.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  79. Increased vascular endothelial growth factor and receptors: relationship to angiogenesis in asthma.
    Authors: Feltis BN, Wignarajah D, Zheng L, Ward C, Reid D, Harding R, Walters EH
    Am. J. Respir. Crit. Care Med., 2006-03-09;173(11):1201-7.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  80. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
    Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
    J. Immunol., 2005-11-01;175(9):6177-89.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Neutralization
  81. Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension.
    Authors: Rodriguez-Porcel M, Zhu XY, Chade AR, Amores-Arriaga B, Caplice NM, Ritman EL, Lerman A, Lerman LO
    Am. J. Physiol. Heart Circ. Physiol., 2005-10-07;290(3):H978-84.
    Species: Porcine
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  82. Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo.
    Authors: Li L, Lin X, Staver M, Shoemaker A, Semizarov D, Fesik SW, Shen Y
    Cancer Res., 2005-08-15;65(16):7249-58.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  83. Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas.
    Authors: Shikada Y, Yonemitsu Y, Koga T, Onimaru M, Nakano T, Okano S, Sata S, Nakagawa K, Yoshino I, Maehara Y, Sueishi K
    Cancer Res., 2005-08-15;65(16):7241-8.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  84. Possible mechanisms inducing glomerulations in interstitial cystitis: relationship between endoscopic findings and expression of angiogenic growth factors.
    Authors: Tamaki M, Saito R, Ogawa O, Yoshimura N, Ueda T
    J. Urol., 2004-09-01;172(3):945-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  85. Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1.
    Authors: Caine GJ, Blann AD, Stonelake PS, Ryan P, Lip GY
    Eur. J. Clin. Invest., 2003-10-01;33(10):883-90.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Development
  86. Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3.
    Authors: Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC
    Cancer Res., 2003-02-15;63(4):887-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  87. Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome.
    Authors: Zhou Y, 2019, McMaster M, Woo K, Janatpour M, Perry J, Karpanen T, Alitalo K, Damsky C, Fisher SJ
    2002-04-01;160(4):1405-23.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  88. Hepatocyte growth factor and vascular endothelial growth factor expression in pig-to-primate xenotransplanted hearts.
    Authors: Takayama K, Suzuki J, Kawauchi M, Tsukioka K, Wada Y, Zhang T, Endoh M, Takamoto S, Amano J, Isobe M
    Transplant. Proc., 2000-08-01;32(5):987-9.
    Species: Porcine
    Sample Types: Whole Tissue
    Applications: IHC-P
  89. Inhibition of Semaphorin As a Novel Strategy for Therapeutic Angiogenesis
    Authors: Junji Moriya, Tohru Minamino, Kaoru Tateno, Sho Okada, Akiyoshi Uemura, Ippei Shimizu et al.
    Circulation Research
  90. Ionizing Radiation-Induced GDF15 Promotes Angiogenesis in Human Glioblastoma Models by Promoting VEGFA Expression Through p-MAPK1/SP1 Signaling
    Authors: Hyejin Park, Ki-Seok Nam, Hae-June Lee, Kwang Seok Kim
    Frontiers in Oncology
  91. Induction of Angiogenesis by Genetically Modified Human Umbilical Cord Blood Mononuclear Cells
    Authors: Dilara Z. Gatina, Ilnaz M. Gazizov, Margarita N. Zhuravleva, Svetlana S. Arkhipova, Maria A. Golubenko, Marina O. Gomzikova et al.
    International Journal of Molecular Sciences
  92. Interleukin-6 as a potential molecular target in esophageal squamous cell carcinoma
    Authors: ZHI-FEI ZHAO, JIAN-XIONG LI, RUI YE, XUAN WU, LING-LING GAO, BAO-LONG NIU
    Oncology Letters
  93. Anti-human Vascular Endothelial Growth Factor (VEGF) Antibody Selection for Immunohistochemical Staining of Proliferating Blood Vessels
    Authors: Chris M. van der Loos, Lorine B. Meijer-Jorna, Marloes E.C. Broekmans, Hanneke P.H.M. Ploegmakers, Peter Teeling, Onno J. de Boer et al.
    Journal of Histochemistry & Cytochemistry
  94. A robust automated measure of average antibody staining in immunohistochemistry images.
    Authors: Choudhury KR, Yagle KJ, Swanson PE et al.
    J Histochem Cytochem
  95. Hypoxia-induced expression of VEGF is reversible in myocardial vascular smooth muscle cells.
    Authors: Gu JW, Adair TH
    Am. J. Physiol., 1997-08-01;273(2):H628-33.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Neutralization
  96. The Proinflammatory and Proangiogenic Macrophage Migration Inhibitory Factor Is a Potential Regulator in Proliferative Diabetic Retinopathy
    Authors: Ahmed M. Abu El-Asrar, Ajmal Ahmad, Mohammad Mairaj Siddiquei, Alexandra De Zutter, Eef Allegaert, Priscilla W. Gikandi et al.
    Frontiers in Immunology
  97. Contrast-Enhanced Ultrasonography Features of Breast Malignancies with Different Sizes: Correlation with Prognostic Factors
    Authors: Li-Xia Zhao, Hui Liu, Qing Wei, Guang Xu, Jian Wu, Hui-Xiong Xu et al.
    BioMed Research International
  98. Tie2/TEK Modulates the Interaction of Glioma and Brain Tumor Stem Cells with Endothelial Cells and Promotes an Invasive Phenotype
    Authors: Dan Liu, Vanesa Martin, Juan Fueyo, Ok-Hee Lee, Jing Xu, Nahir Cortes-Santiago et al.
    ImpactJ
  99. Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription
    Authors: Yang Gao, Kaijie Wu, Yule Chen, Jiancheng Zhou, Chong Du, Qi Shi et al.
    Oncotarget
  100. DCE-MRI in Glioma, Infiltration Zone and Healthy Brain to Assess Angiogenesis: A Biopsy Study
    Authors: Vera C. Keil, Gerrit H. Gielen, Bogdan Pintea, Peter Baumgarten, Angeliki Datsi, Kanishka Hittatiya et al.
    Clinical Neuroradiology
  101. Upregulation of Thrombin/Matrix Metalloproteinase-1/Protease-Activated Receptor-1 Chain in Proliferative Diabetic Retinopathy
    Authors: Ahmed M. Abu El-Asrar, Kaiser Alam, Mohd Imtiaz Nawaz, Ghulam Mohammad, Kathleen Van den Eynde, Mohammad Mairaj Siddiquei et al.
    Current Eye Research
  102. Dimethyloxalyglycine stimulates the early stages of gastrointestinal repair processes through VEGF-dependent mechanisms
    Authors: Tania Marchbank, Asif Mahmood, Sarah Harten, Patrick H Maxwell, Raymond J Playford
    Laboratory Investigation
  103. Identification of novel neutralizing single-chain antibodies against vascular endothelial growth factor receptor 2
    Authors: Berrin Erdag, B Koray Koray Balcioglu, Aylin Ozdemir Ozdemir Bahadir, Muge Serhatli, Omer Kacar, Aydin Bahar et al.
    Biotechnology and Applied Biochemistry
  104. Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake
    Authors: Song Yi Ko, WonJae Lee, Hilary A. Kenny, Long H. Dang, Lee M. Ellis, Eric Jonasch et al.
    Communications Biology
  105. VEGF, FLT3 ligand, PlGF and HGF can substitute for M-CSF to induce human osteoclast formation: implications for giant cell tumour pathobiology
    Authors: Richard M Taylor, Takeshi G Kashima, Helen J Knowles, Nicholas A Athanasou
    Laboratory Investigation
  106. B7-H3 promotes colorectal cancer angiogenesis through activating the NF-kappa B pathway to induce VEGFA expression
    Authors: Ruoqin Wang, Yanchao Ma, Shenghua Zhan, Guangbo Zhang, Lei Cao, Xueguang Zhang et al.
    Cell Death & Disease
  107. Roundabout4 Suppresses Glioma-Induced Endothelial Cell Proliferation, Migration and Tube Formation in Vitro by Inhibiting VEGR2-Mediated PI3K/AKT and FAK Signaling Pathways
    Authors: Heng Cai, Yixue Xue, Zhen Li, Yi Hu, Zhenhua Wang, Wenjing Liu et al.
    Cellular Physiology and Biochemistry
  108. Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy
    Authors: Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Ajmal Ahmad, Alexandra De Zutter, Mohammad Mairaj Siddiquei, Marfa Blanter et al.
    Frontiers in Immunology
  109. Strong Expression of Hypoxia-Inducible Factor-1alpha (HIF-1alpha) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer.
    Authors: Nalwoga H, Ahmed L, Arnes J, Wabinga H, Akslen L
    PLoS ONE, 2016-01-13;11(1):e0146823.
  110. Platelet-derived adenosine 5′-triphosphate suppresses activation of human hepatic stellate cell: In vitro study
    Authors: Naoya Ikeda, Soichiro Murata, Takehito Maruyama, Takafumi Tamura, Reiji Nozaki, Takuya Kawasaki et al.
    Hepatology Research

FAQs

  1. What are the differences between MAB293 and MAB293R?

    • MAB293 is produced by culturing a hybridoma cell line, whereas MAB293R is produced via recombinant DNA technology, based on the known, proprietary sequence of MAB293.  The benefit of recombinant antibodies is the ability to offer a more consistent antibody, with an indefinite supply.  As far as research applications, both products will work the same.

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Reviews for Human/Primate VEGF Antibody

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Human/Primate VEGF Antibody
By Anonymous on 02/14/2022
Application: WB Sample Tested: THP-1 human acute monocytic leukemia cell line Species: Human
Human/Primate VEGF Antibody
By Anonymous on 08/09/2021
Application: WB Sample Tested: Metastatic breast cancer Species: Human
Human/Primate VEGF Antibody
By Karina Kinghorn on 07/16/2021
Application: Immunocytochemistry/Immunofluorescence Sample Tested: HUVEC human umbilical vein endothelial cells Species: Human

IF of HUVEC cells with exogenous VEGF internalized (red) and colocalizing with VEGF receptor (green)

Human/Primate VEGF Antibody
By Anonymous on 05/27/2019
Application: B/N Sample Tested: Breast cancer cells,Serum-free Cell Culture Media Species: Human
Human/Primate VEGF Antibody
By Anonymous on 03/13/2019
Application: B/N Sample Tested: HUVEC human umbilical vein endothelial cells Species: Human

We used this VEGF-A neutralizing antibody (10 ng/mL) as part of an antibody cocktail containing several other antibodies to neutralize VEGF-A present in the Conditioned Medium (CM) from BT549 Cells treated with Angiotensin II CM (+/- VEGF-A Neutralizing ab Cocktail) was used to further look at Endothelial (HUVEC) Cell migration using Incucyte Chemotaxis Assay.
Cancer Res; 78(5) March 1, 2018 (Fig 6F)

Block/Neutralize Human/Primate VEGF Antibody MAB293
Human/Primate VEGF Antibody
By Zoia Levashova on 06/22/2018
Application: Meso Scale Discovery Sample Tested: Aqueous humor,Retina/choroid,Vitreous humor Species: Porcine

After biotinylation, used as a capture reagent in MSD assay to detect ocular VEGF level in a swine model of laser-induced choroidal neovascularization. A standard curve with pig VEGF from Bio-Rad (Cat# PPP030) is shown (2-8,000 pg/ml).

Other Human/Primate VEGF Antibody MAB293
Human/Primate VEGF Antibody
By Alisha Freeman on 11/04/2017
Application: ELISA Sample Tested: CHO Chinese hamster ovary cell line Species: Hamster
Human/Primate VEGF Antibody
By Anonymous on 08/18/2017
Application: ELISA Sample Tested: THP-1 human acute monocytic leukemia cell line Species: Human
ELISA Human/Primate VEGF Antibody MAB293