Human SLC14A1 Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB8238R-100UG
R&D Systems Antibodies
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Human SLC14A1 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human SLC14A1 in direct ELISAs.
Source
Monoclonal Mouse IgG2b Clone # 888418
Immunogen
NS0 mouse myeloma cell line transfected with human SLC14A1
Accession # Q13336
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Human red blood cells and HEK293 human embryonic kidney cell line transfected with human SLC14A1 and eGFP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: SLC14A1

Urea transporter 1, designated Solute Carrier family 14 member 1 (SLC14A1) is a 43-54 kDa multipass urea transporter mainly expressed in erythrocytes, but also found in kidney, mesenchymal stem cells, and some carcinomas. It contains an epitope identified as the Kidd (JK) blood group antigen. The antigenic forms differ at only one amino acid (aa); Asp280 represents Jk(a) and Asn280 represents Jk(b). SLC14A1 Isoform 2 (445 aa) contains an extended N-terminus as compared to Isoform 1 (389 aa). Human SLC14A1 shares 83% and 81% aa sequence identity with mouse and rat SLC14A1, respectively.

Long Name
Solute Carrier Family 14 (Urea Transporter), Member 1 (Kidd Blood Group
Entrez Gene IDs
6563 (Human); 108052 (Mouse); 54301 (Rat)
Alternate Names
FLJ33745; HsT1341; HUT11; JK; JKFLJ41687; RACH1; RACH2; SLC14A1; solute carrier family 14 (urea transporter), member 1 (Kidd blood group); Solute carrier family 14 member 1; truncated urea transporter; urea transporter 1; urea transporter JK glycoprotein; Urea transporter, erythrocyte; urea transporter-B1; UT1; UT1UT-B1; UT-B1; UTE; UTEblood group Kidd urea transporter

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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