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Human Stanniocalcin 2/STC-2 Antibody

Catalog #: AF2830
4 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF2830
AF2830-SP
Product Details
Citations (4)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Stanniocalcin 2/STC-2 Antibody Summary

Species Reactivity
Human
Specificity
Detects human and mouse Stanniocalcin 2/STC‑2 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross‑reactivity with recombinant human STC-1 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Stanniocalcin 2/STC‑2
Thr25-Arg302
Accession # O76061
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human Stanniocalcin 2/STC‑2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Stanniocalcin 2/STC-2

STC-2 is a secreted disulfide-linked homodimeric glycoprotein hormone that is related to the STC protein first discovered from corpuscles of stannius in fish. STC2 is expressed in a wide variety of tissues. In the ovary, STC2 has been shown to be a paracrine hormone that regulates granulosa cell function. The amino acid sequence of human mature STC2 is 36% identical to that of human STC1. It is also 99%, and 88% identical to that of mature monkey and mouse STC2, respectively.

Entrez Gene IDs
8614 (Human); 20856 (Mouse)
Alternate Names
Stanniocalcin 2; stanniocalcin-2; STC2; STC-2; STC-2Stanniocalcin-related protein; STC-related protein; STCRP

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Citations for Human Stanniocalcin 2/STC-2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. Rare and low-frequency coding variants alter human adult height
    Authors: E Marouli, M Graff, C Medina-Gom, KS Lo, AR Wood, TR Kjaer, RS Fine, Y Lu, C Schurmann, HM Highland, S Reger, G Thorleifss, AE Justice, D Lamparter, KE Stirrups, V Turcot, KL Young, TW Winkler, T Esko, T Karaderi, AE Locke, NG Masca, MC Ng, P Mudgal, MA Rivas, S Vedantam, A Mahajan, X Guo, G Abecasis, KK Aben, LS Adair, DS Alam, E Albrecht, KH Allin, M Allison, P Amouyel, EV Appel, D Arveiler, FW Asselbergs, PL Auer, B Balkau, B Banas, LE Bang, M Benn, S Bergmann, LF Bielak, M Blher, H Boeing, E Boerwinkle, CA B”ger, LL Bonnycastl, J Bork-Jense, ML Bots, EP Bottinger, DW Bowden, I Brandslund, G Breen, MH Brilliant, L Broer, AA Burt, AS Butterwort, DJ Carey, MJ Caulfield, JC Chambers, DI Chasman, YI Chen, R Chowdhury, C Christense, AY Chu, M Cocca, FS Collins, JP Cook, J Corley, JC Galbany, AJ Cox, G Cuellar-Pa, J Danesh, G Davies, PI de Bakker, GJ de Borst, S de Denus, MC de Groot, R de Mutsert, IJ Deary, G Dedoussis, EW Demerath, AI den Hollan, JG Dennis, E Di Angelan, F Drenos, M Du, AM Dunning, DF Easton, T Ebeling, TL Edwards, PT Ellinor, P Elliott, E Evangelou, AE Farmaki, JD Faul, MF Feitosa, S Feng, E Ferrannini, MM Ferrario, J Ferrieres, JC Florez, I Ford, M Fornage, PW Franks, R Frikke-Sch, TE Galesloot, W Gan, I Gandin, P Gasparini, V Giedraitis, A Giri, G Girotto, SD Gordon, P Gordon-Lar, M Gorski, N Grarup, ML Grove, V Gudnason, S Gustafsson, T Hansen, KM Harris, TB Harris, AT Hattersley, C Hayward, L He, IM Heid, K Heikkil„, ? Helgeland, J Hernesniem, AW Hewitt, LJ Hocking, M Hollensted, OL Holmen, GK Hovingh, JM Howson, CB Hoyng, PL Huang, K Hveem, MA Ikram, E Ingelsson, AU Jackson, JH Jansson, GP Jarvik, GB Jensen, MA Jhun, Y Jia, X Jiang, S Johansson, ME J?rgensen, T J?rgensen, P Jousilahti, JW Jukema, B Kahali, RS Kahn, M K„h”nen, PR Kamstrup, S Kanoni, J Kaprio, M Karalefthe, SL Kardia, F Karpe, F Kee, R Keeman, LA Kiemeney, H Kitajima, KB Kluivers, T Kocher, P Komulainen, J Kontto, JS Kooner, C Kooperberg, P Kovacs, J Kriebel, H Kuivaniemi, S Kry, J Kuusisto, M La Bianca, M Laakso, TA Lakka, EM Lange, LA Lange, CD Langefeld, C Langenberg, EB Larson, IT Lee, T Lehtim„ki, CE Lewis, H Li, J Li, R Li-Gao, H Lin, LA Lin, X Lin, L Lind, J Lindstr”m, A Linneberg, Y Liu, Y Liu, A Lophatanan, J Luan, SA Lubitz, LP Lyytik„ine, DA Mackey, PA Madden, AK Manning, S M„nnist”, G Marenne, J Marten, NG Martin, AL Mazul, K Meidtner, A Metspalu, P Mitchell, KL Mohlke, DO Mook-Kanam, A Morgan, AD Morris, AP Morris, M Mller-Nur, PB Munroe, MA Nalls, M Nauck, CP Nelson, M Neville, SF Nielsen, K Nikus, PR Nj?lstad, BG Nordestgaa, I Ntalla, JR O'Connel, H Oksa, LM Loohuis, RA Ophoff, KR Owen, CJ Packard, S Padmanabha, CN Palmer, G Pasterkamp, AP Patel, A Pattie, O Pedersen, PL Peissig, GM Peloso, CE Pennell, M Perola, JA Perry, JR Perry, TN Person, A Pirie, O Polasek, D Posthuma, OT Raitakari, A Rasheed, R Rauramaa, DF Reilly, AP Reiner, F Renstr”m, PM Ridker, JD Rioux, N Robertson, A Robino, O Rolandsson, I Rudan, KS Ruth, D Saleheen, V Salomaa, NJ Samani, K Sandow, Y Sapkota, N Sattar, MK Schmidt, PJ Schreiner, MB Schulze, RA Scott, MP Segura-Lep, S Shah, X Sim, S Sivapalara, KS Small, AV Smith, JA Smith, L Southam, TD Spector, EK Speliotes, JM Starr, V Steinthors, HM Stringham, M Stumvoll, P Surendran, LM 't Hart, KE Tansey, JC Tardif, KD Taylor, A Teumer, DJ Thompson, U Thorsteins, BH Thuesen, A T”njes, G Tromp, S Trompet, E Tsafantaki, J Tuomilehto, A Tybjaerg-H, JP Tyrer, R Uher, AG Uitterlind, S Ulivi, SW van der La, AR Van Der Le, CM van Duijn, NM van Schoor, J van Setten, A Varbo, TV Varga, R Varma, DR Edwards, SH Vermeulen, H Vestergaar, V Vitart, TF Vogt, D Vozzi, M Walker, F Wang, CA Wang, S Wang, Y Wang, NJ Wareham, HR Warren, J Wessel, SM Willems, JG Wilson, DR Witte, MO Woods, Y Wu, H Yaghootkar, J Yao, P Yao, LM Yerges-Arm, R Young, E Zeggini, X Zhan, W Zhang, JH Zhao, W Zhao, W Zhao, H Zheng, W Zhou, JI Rotter, M Boehnke, S Kathiresan, MI McCarthy, CJ Willer, K Stefansson, IB Borecki, DJ Liu, KE North, NL Heard-Cost, TH Pers, CM Lindgren, C Oxvig, Z Kutalik, F Rivadeneir, RJ Loos, TM Frayling, JN Hirschhorn, P Deloukas, G Lettre
    Nature, 2017-02-01;0(0):.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Western Blot
  2. Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A.
    Authors: Kloverpris S, Mikkelsen J, Pedersen J, Jepsen M, Laursen L, Petersen S, Oxvig C
    J Biol Chem, 2015-07-20;290(36):21915-24.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Western Blot
  3. Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis.
    Authors: Jepsen M, Kloverpris S, Mikkelsen J, Pedersen J, Fuchtbauer E, Laursen L, Oxvig C
    J Biol Chem, 2014-12-22;290(6):3430-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Western Blot
  4. Survival analyses correlate stanniocalcin 2 overexpression to poor prognosis of nasopharyngeal carcinomas.
    Authors: Lin S, Guo Q, Wen J, Li C, Lin J, Cui X, Sang N, Pan J
    J Exp Clin Cancer Res, 2014-03-08;33(0):26.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC

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