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Human STAT2 (NP_005410.1) VersaClone cDNA

Catalog #: RDC3294 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
RDC3294
Human STAT2 (NP_005410.1) VersaClone cDNA
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Human STAT2 (NP_005410.1) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Product Datasheet
COA
SDS
SDS

Background: STAT2

Signal transducer and activator of transcription 2 (STAT2) has an apparent M.W. of 113 kDa in SDS-PAGE gels. Human STAT2 is 851 amino acids (aa) in length and contains one SH2 domain (aa 572-667). Splicing variants produce two isoforms for human STAT2. The short isoform has a 32 aa substitution and a 199 aa deletion corresponding to aa 621 - 652 and aa 653 - 851 in the long isoform, respectively. Human STAT2 shares 73% and 65% aa sequence identity with rat and mouse STAT2, in that order. STAT2 functions as a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-α and IFN-β), and it is also required for myogenic differentiation.

Long Name
Signal Transducer and Activator of Transcription 2
Entrez Gene IDs
6773 (Human); 20847 (Mouse)
Alternate Names
interferon alpha induced transcriptional activator; ISGF-3; MGC59816; P113; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kD; signal transducer and activator of transcription 2, 113kDa; STAT113; STAT2

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