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Kinesore

Catalog #: 6664 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6664/50
6664/10
Kinesore | CAS No. 363571-83-9 | Kinesin Inhibitors
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Description: Kinesin-1 modulator; cell permeable

Chemical Name: 3,5-Dibromo-N'-((2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl)methylene)-4-hydroxybenzohydrazide

Purity: ≥98%

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Biological Activity

Kinesore is a kinesin-1 modulator. Inhibits SKIP-KLC2 interaction, but promotes kinesin-1 function in controlling the organization of the microtubule network. Induces remodeling of the microtubule network and the formation of extensive microtubule-rich projections. Cell permeable.

Technical Data

M.Wt:
536.17
Formula:
C20H16Br2N4O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
363571-83-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.
    Randall et al.
    Proc.Natl.Acad.Sci.USA, 2017;114:13743

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