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L-DOPA

Catalog #: 3788
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3788/50
L-DOPA | CAS No. 59-92-7 | Non-selective Dopamine Receptor Products
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Description: Dopamine precursor
Alternative Names: Levodopa

Chemical Name: L-3,4-Dihydroxyphenylalanine

Purity: ≥98%

Product Details
Citations (5)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

L-DOPA is an immediate precursor of dopamine, produced by tyrosine hydroxylase. Displays antiParkinsonian activity.

Technical Data

M.Wt:
197.19
Formula:
C9H11NO4
Solubility:
Soluble to 5 mM in water and to 50 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
59-92-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Levodopa-induced dyskinesia and striatal signaling pathways.
    Pisani and Shen
    Proc.Natl.Acad.Sci.USA, 2009;106:2973

Product Datasheets

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

⚠ WARNING: This product can expose you to chemicals including Levodopa, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citations for L-DOPA

The citations listed below are publications that use Tocris products. Selected citations for L-DOPA include:

5 Citations: Showing 1 - 5

  1. Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson's disease.
    Authors: Robert Et al.
    J Neuroinflammation  2022;19:50
  2. Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways.
    Authors: Marc Et al.
    Cell Rep  2021;35:109136
  3. Cocaine shifts dopamine D2 receptor sensitivity to gate conditioned behaviors.
    Authors: Christopher P Et al.
    Neuron  2021;109:3421-3435.e5
  4. Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum.
    Authors: Alexander G Et al.
    Elife  2021;10
  5. A Basal Ganglia Circuit Sufficient to Guide Birdsong Learning.
    Authors: Xiao Et al.
    Neuron  2018;98:208

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