Mag-Fura-2 AM
Chemical Name: Bis(acetoxymethyl) 2,2'-((5-(2-(acetoxymethoxy)-2-oxoethoxy)-2-(5-((acetoxymethoxy)carbonyl)oxazol-2-yl)benzofuran-6-yl)azanediyl)diacetate
Purity: ≥95%
Biological Activity
Mag-Fura-2 AM is a cell-permeable fluorescent magnesium ion (Mg2+) indicator. It shows selectivity for Mg2+ over other bivalent ions (Zn2+, Cu2+ and Ca2+). It exhibits >13,000-fold selectivity for Mg2+ ions over Ca2+ ions (Mg2+ Kd = 1.9 nM vs Ca2+ Kd = 25 μM). Excitation and emission maxima (λ) are 369 and 511 nm, respectively. Mag-Fura-2 AM can be used as an indirect indicator of ATP consumption/production.It is recommended to prepare stock solutions in DMSO.
Optical Data for Mag-Fura-2 AM
| λabs | 369 nm |
|---|---|
| λem | 511 nm |
| Extinction Coefficient (ε) | 31000 M-1cm-1 |
| Cell Permeable | Yes |
| Application | Confocal Imaging, Flow Cytometry |
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Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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