Mca-SEVNLDAEFRK(Dnp)RR-NH2 Fluorogenic Peptide Substrate
Mca-SEVNLDAEFRK(Dnp)RR-NH2 Fluorogenic Peptide Substrate Summary
Product Specifications
Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2
Mca: (7-Methoxycoumarin-4-yl) acetyl, Dnp: 2, 4-Dinitrophenyl
Product Datasheets
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
ES004
Formulation | Supplied as a stock solution in dimethyl sulfoxide (DMSO) (100 μL) at a concentration of 10.0 mg/mL or 4.1 mM.. |
Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light |
Reconstitution Calculator
Citations for Mca-SEVNLDAEFRK(Dnp)RR-NH2 Fluorogenic Peptide Substrate
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 7
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Dual Inhibitors of AChE and BACE-1 for Reducing Abeta in Alzheimer's Disease: From In Silico to In Vivo
Authors: N Stern, A Gacs, E Tátrai, B Flachner, I Hajdú, K Dobi, I Bágyi, G Dormán, Z L?rincz, S Cseh, A Kígyós, J Tóvári, A Goldblum
International Journal of Molecular Sciences, 2022-10-28;23(21):.
Species: Human
Sample Types: Peptide
Applications: Bioassay -
The botanical origin and antioxidant, anti-BACE1 and antiproliferative properties of bee pollen from different regions of South Korea
Authors: Y Zou, J Hu, W Huang, L Zhu, M Shao, C Dordoe, YJ Ahn, D Wang, Y Zhao, Y Xiong, X Wang
BMC Complement Med Ther, 2020-07-25;20(1):236.
Applications: Enzyme Assay -
Evaluation of an Allosteric BACE inhibitor peptide to identify mimetics that can interact with the Loop F Region of the enzyme and prevent APP cleavage
Authors: J Campagna, K Vadivel, B Jagodzinsk, M Jun, T Bilousova, P Spilman, V John
J. Mol. Biol., 2018-04-10;0(0):.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay -
Gleevec shifts APP processing from a ?-cleavage to a nonamyloidogenic cleavage
Authors: WJ Netzer, K Bettayeb, SC Sinha, M Flajolet, P Greengard, V Bustos
Proc. Natl. Acad. Sci. U.S.A, 2017-01-23;0(0):.
Species: Human
Sample Types: Protein
Applications: Enzyme Assay -
Localization and Processing of�the�Amyloid-? Protein Precursor in�Mitochondria-Associated Membranes
Authors: Dolores Del Prete
J. Alzheimers Dis, 2017-01-01;0(0):.
Applications: Bioassay -
Inhibition of amyloid beta-peptide production by blockage of beta-secretase cleavage site of amyloid precursor protein.
Authors: Na CH, Jeon SH, Zhang G, Olson GL, Chae CB
J. Neurochem., 2007-06-01;101(6):1583-95.
Species: Human
Sample Types: Recombinant Protein
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BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors.
Authors: Andrau D, 107291, Dumanchin-Njock C, Ayral E, Vizzavona J, Farzan M, Boisbrun M, Fulcrand P, Hernandez JF, Martinez J, Lefranc-Jullien S, Checler F
Microglia activation and inflammation in hippocampus attenuates memory and mood functions during experimentally induced diabetes in rat, 2003-05-07;278(28):25859-66.
Species: Human
Sample Types: Cell Lysates
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