Mouse GFR alpha-4/GDNF R alpha-4 Antibody

Catalog #: MAB1677 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB1677
MAB1677-SP

All GFR alpha-4/GDNF R alpha-4 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse GFR alpha-4/GDNF R alpha-4 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse GFR alpha ‑4/GDNF R alpha ‑4 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse GFR alpha -2, recombinant human (rh) GFR alpha -3, recombinant rat GFR alpha -1, or rhGFR alpha -4 is observed.

Source

Monoclonal Rat IgG_2A Clone # 171217

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse GFR alpha ‑4/GDNF R alpha ‑4

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Immunohistochemistry

8-25 µg/mL

Perfusion fixed frozen sections of mouse brain (cortex, hippocampus, substantia nigra, and cerebellum)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: GFR alpha-4/GDNF R alpha-4

GFR alpha -4 is a GPI-linked cell surface protein that associates with the c-Ret transmembrane tyrosine kinase to form a functional receptor complex for the GDNF family ligand, persephin.

Long Name

Glial Cell line-derived Neurotrophic Factor Receptor alpha 4

Entrez Gene IDs

64096 (Human); 14588 (Mouse)

Alternate Names

GDNF family receptor alpha 4; GDNF family receptor alpha-4; GDNF R alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha4; GFR alpha-4; GFR receptor alpha 4; GFRA4; GFRa-4; GFR-alpha-4; Persephin receptor