Mouse IGSF2/CD101 Antibody

Catalog #: MAB3368
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB3368
MAB3368-SP

All IGSF2/CD101 Antibodies

Product Details

Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IGSF2/CD101 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse IGSF2/CD101.

Source

Monoclonal Rat IgG_2A Clone # 307707

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant mouse IGSF2/CD101
Gln21-Tyr1033
Accession # A8E0Y8

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Purity

Protein A or G purified from hybridoma culture supernatant

Applications

Recommended Concentration

Sample

Flow Cytometry

2.5 µg/10⁶ cells

Mouse peripheral blood GR‑1⁺ granulocytes

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IGSF2/CD101

IGSF2, also known as CD101, is an Ig-superfamily transmembrane protein. It is expressed on dendritic cells, Langerhans cells, granulocytes, and activated T cells. IGSF2 ligation is involved in T cell activation. Polymorphisms in IGSF2 are associated with susceptibility to type I diabetes. The extracellular domains of mouse and human IGSF2 share 70% amino acid sequence identity.

Long Name

Immunoglobulin Superfamily, Member 2

Entrez Gene IDs

9398 (Human); 630146 (Mouse)

Alternate Names

CD101 antigen; CD101 molecule; CD101; Cell surface glycoprotein V7; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; IGSF2; Leukocyte Surface Protein; member 2; V7

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse IGSF2/CD101 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice
Authors: J Mattner, JP Mohammed, ME Fusakio, C Giessler, CP Hackstein, R Opoka, M Wrage, R Schey, J Clark, HI Fraser, DB Rainbow, LS Wicker
PLoS Genet., 2019-06-14;15(6):e1008178.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

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